Apellis Pharmaceuticals, Inc.
APLSDelisted- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001492422
Apellis Pharmaceuticals, Inc. was delisted in 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.
13F holders, Q2 2025
Institutional positions in Apellis Pharmaceuticals, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 247
- −6 vs. Q1 2025
- Shares held
- 131.5M
- +3.54M (+2.8%) vs. Q1 2025
- Total value
- $2.28B
- −$523.6M (−18.7%) vs. Q1 2025
- New holders
- 43
- 108 more added
- Sold out
- 49
- 68 more reduced
2 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1 | $10.2K |
| Q1 2026 | 324 | $5.56B |
| Q4 2025 | 280 | $3.17B |
| Q3 2025 | 273 | $2.77B |
| Q2 2025 | 247 | $2.29B |
| Q1 2025 | 255 | $2.80B |
| Q4 2024 | 260 | $4.05B |
| Q3 2024 | 265 | $3.52B |
| Q2 2024 | 263 | $4.56B |
| Q1 2024 | 302 | $6.97B |
| Q4 2023 | 284 | $7.16B |
| Q3 2023 | 256 | $4.34B |
| Q2 2023 | 317 | $9.81B |
| Q1 2023 | 282 | $7.49B |
| Q4 2022 | 244 | $5.26B |
| Q3 2022 | 250 | $6.67B |
| Q2 2022 | 212 | $4.15B |
| Q1 2022 | 212 | $4.62B |
| Q4 2021 | 187 | $3.91B |
| Q3 2021 | 181 | $2.29B |
| Q2 2021 | 205 | $4.13B |
| Q1 2021 | 175 | $2.80B |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Avoro Capital Advisors LLC | 12,222,222 | $211.6M | 3.71% | 00.0% | Unchanged |
| EcoR1 Capital, LLC | 11,895,808 | $205.9M | 12.20% | 00.0% | Unchanged |
| Vanguard Group Inc | 10,154,751 | $175.8M | 0.00% | +24,395+0.2% | Added |
| Morgan Stanley | 9,752,201 | $168.8M | 0.01% | +126,078+1.3% | Added |
| Wellington Management Group LLP | 8,976,962 | $155.4M | 0.03% | −3,326,290−27.0% | Reduced |
| Deep Track Capital, LP | 7,000,000 | $121.2M | 3.90% | +2,000,000+40.0% | Added |
| BlackRock, Inc. | 6,404,999 | $110.9M | 0.00% | +75,401+1.2% | Added |
| AQR Capital Management LLC | 5,976,414 | $103.5M | 0.09% | +1,898,995+46.6% | Added |
| UBS Group AG | 4,735,311 | $82.0M | 0.02% | +1,463,117+44.7% | Added |
| State Street Corp | 3,562,721 | $61.7M | 0.00% | −378,684−9.6% | Reduced |
| Suvretta Capital Management, LLC | 2,878,000 | $49.8M | 1.88% | +1,231,385+74.8% | Added |
| Marshall Wace, LLP | 2,704,837 | $46.8M | 0.06% | +2,681,263+11,373.8% | Added |
| Jennison Associates LLC | 2,661,823 | $46.1M | 0.03% | +184,292+7.4% | Added |
| Siren, L.L.C. | 2,578,396 | $44.6M | 2.31% | 00.0% | Unchanged |
| Bank of America Corp | 2,426,628 | $42.0M | 0.00% | −704,808−22.5% | Reduced |
| Norges Bank | 2,367,224 | $41.0M | 0.01% | +793,623+50.4% | Added |
| Geode Capital Management, LLC | 1,995,271 | $34.5M | 0.00% | +45,225+2.3% | Added |
| Amundi | 1,604,105 | $28.6M | 0.01% | +1,274,523+386.7% | Added |
| Deutsche Bank AG | 1,496,296 | $25.9M | 0.01% | −280,280−15.8% | Reduced |
| OrbiMed Advisors LLC | 1,482,300 | $25.7M | 0.65% | +50,000+3.5% | Added |
| Polar Capital Holdings Plc | 1,352,175 | $23.4M | 0.12% | −225,000−14.3% | Reduced |
| BNP Paribas Arbitrage, SA | 1,298,459 | $22.5M | 0.02% | +187,750+16.9% | Added |
| Braidwell LP | 1,121,034 | $19.4M | 0.66% | −531,300−32.2% | Reduced |
| Wells Fargo & Company | 1,043,655 | $18.1M | 0.00% | +1,039,031+22,470.4% | Added |
| Charles Schwab Investment Management Inc | 989,143 | $17.1M | 0.00% | +24,644+2.6% | Added |
| Octagon Capital Advisors LP | 903,500 | $15.6M | 3.43% | −1,190,500−56.9% | Reduced |
| Camber Capital Management LP | 850,000 | $14.7M | 2.05% | +850,000 | New |
| Royal Bank of Canada | 797,585 | $13.8M | 0.00% | +2,650+0.3% | Added |
| Ameriprise Financial Inc | 750,161 | $13.0M | 0.00% | +283,500+60.8% | Added |
| Bank of Nova Scotia | 594,812 | $10.3M | 0.02% | +594,812 | New |
| Jefferies Financial Group Inc. | 578,205 | $10.0M | 0.17% | −21,050−3.5% | Reduced |
| Jump Financial, LLC | 558,668 | $9.67M | 0.12% | +293,075+110.3% | Added |
| Ossiam | 555,953 | $9.62M | 0.11% | +555,953 | New |
| Capitolis Liquid Global Markets LLC | 544,600 | $9.43M | 0.07% | +544,600 | New |
| Woodline Partners LP | 530,923 | $9.19M | 0.05% | +312,073+142.6% | Added |
| Northern Trust Corp | 525,882 | $9.10M | 0.00% | +7,188+1.4% | Added |
| Schroder Investment Management Group | 485,615 | $8.41M | 0.01% | +232,506+91.9% | Added |
| Hudson Bay Capital Management LP | 475,000 | $8.22M | 0.05% | +164,300+52.9% | Added |
| Nuveen, LLC | 469,253 | $8.12M | 0.00% | −22,985−4.7% | Reduced |
| Voloridge Investment Management, LLC | 468,710 | $8.11M | 0.03% | +214,920+84.7% | Added |
| Citadel Advisors LLC | 442,560 | $7.66M | 0.01% | +218,464+97.5% | Added |
| 683 Capital Management, LLC | 410,000 | $7.10M | 0.72% | +77,000+23.1% | Added |
| Two Sigma Investments, LP | 406,913 | $7.04M | 0.01% | +144,009+54.8% | Added |
| Pictet Asset Management Holding SA | 348,349 | $6.07M | 0.01% | +33,507+10.6% | Added |
| Ieq Capital, LLC | 346,923 | $6.01M | 0.04% | +55,065+18.9% | Added |
| Canada Pension Plan Investment Board | 336,800 | $5.83M | 0.00% | −711,900−67.9% | Reduced |
| Squarepoint Ops LLC | 329,392 | $5.70M | 0.01% | −113,401−25.6% | Reduced |
| Susquehanna International Group, LLP | 328,726 | $5.69M | 0.01% | +299,221+1,014.1% | Added |
| Trexquant Investment LP | 327,421 | $5.67M | 0.06% | −57,501−14.9% | Reduced |
| ING Groep NV | 308,300 | $5.34M | 0.03% | +124,100+67.4% | Added |
| UBS Asset Management Americas Inc | 301,939 | $5.23M | 0.00% | +79,305+35.6% | Added |
| Barclays PLC | 273,912 | $4.74M | 0.00% | +82,675+43.2% | Added |
| Two Sigma Advisers, LP | 256,800 | $4.45M | 0.01% | +65,000+33.9% | Added |
| D. E. Shaw & Co., Inc. | 251,069 | $4.35M | 0.00% | +251,069 | New |
| Jane Street Group, LLC | 246,199 | $4.26M | 0.01% | −9,893−3.9% | Reduced |
| Bank of New York Mellon Corp | 243,327 | $4.21M | 0.00% | −85,846−26.1% | Reduced |
| JPMorgan Chase & Co | 234,801 | $4.06M | 0.00% | −188,999−44.6% | Reduced |
| Caption Management, LLC | 230,888 | $4.00M | 0.37% | +218,888+1,824.1% | Added |
| Edgestream Partners, L.P. | 218,392 | $3.78M | 0.11% | −22,895−9.5% | Reduced |
| Goldman Sachs Group Inc | 215,999 | $3.74M | 0.00% | −91,710−29.8% | Reduced |
| Fiduciary Trust Co | 202,536 | $3.51M | 0.04% | −800−0.4% | Reduced |
| Millennium Management LLC | 202,452 | $3.50M | 0.00% | −249,521−55.2% | Reduced |
| Aquatic Capital Management LLC | 176,704 | $3.06M | 0.06% | −39,172−18.1% | Reduced |
| Invesco Ltd. | 166,135 | $2.88M | 0.00% | −475,262−74.1% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 164,275 | $2.84M | 0.07% | +134,698+455.4% | Added |
| PDT Partners, LLC | 160,058 | $2.77M | 0.16% | −35,107−18.0% | Reduced |
| Bank of Montreal | 159,613 | $2.76M | 0.00% | +1,040+0.7% | Added |
| Algert Global LLC | 154,113 | $2.67M | 0.06% | −184,500−54.5% | Reduced |
| Prudential Financial Inc | 154,010 | $2.67M | 0.00% | −63,870−29.3% | Reduced |
| Voya Investment Management LLC | 150,593 | $2.61M | 0.00% | +25,192+20.1% | Added |
| Rafferty Asset Management, LLC | 143,852 | $2.49M | 0.01% | −36,282−20.1% | Reduced |
| Swiss National Bank | 143,800 | $2.49M | 0.00% | +11,200+8.4% | Added |
| Steward Partners Investment Advisory, LLC | 140,975 | $2.44M | 0.02% | +18,800+15.4% | Added |
| Citigroup Inc | 138,451 | $2.40M | 0.00% | −278,168−66.8% | Reduced |
| California Public Employees Retirement System | 134,637 | $2.33M | 0.00% | +7,931+6.3% | Added |
| CWM, LLC | 127,584 | $2.21M | 0.01% | +29,326+29.8% | Added |
| Rhumbline Advisers | 122,002 | $2.11M | 0.00% | −2,452−2.0% | Reduced |
| Gotham Asset Management, LLC | 119,229 | $2.06M | 0.01% | +84,944+247.8% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 118,724 | $2.06M | 0.01% | −13,171−10.0% | Reduced |
| J. Safra Sarasin Holding AG | 115,684 | $2.00M | 0.03% | +68,588+145.6% | Added |
| Cerity Partners LLC | 114,745 | $1.99M | 0.00% | +60,301+110.8% | Added |
| Sphera Funds Management Ltd. | 114,346 | $1.98M | 0.52% | −67,000−36.9% | Reduced |
| HRT Financial LP | 107,200 | $1.85M | 0.01% | +107,200 | New |
| Wealth Enhancement Advisory Services, LLC | 100,666 | $1.84M | 0.00% | +30,507+43.5% | Added |
| EFG Asset Management (North America) Corp. | 105,024 | $1.82M | 0.26% | +65,661+166.8% | Added |
| Dark Forest Capital Management LP | 104,725 | $1.81M | 0.07% | +104,725 | New |
| Exome Asset Management LLC | 98,600 | $1.71M | 1.41% | +98,600 | New |
| Legal & General Group Plc | 96,050 | $1.66M | 0.00% | +16,980+21.5% | Added |
| Verition Fund Management LLC | 95,605 | $1.65M | 0.01% | −14,905−13.5% | Reduced |
| State of Wisconsin Investment Board | 94,404 | $1.63M | 0.00% | +9,789+11.6% | Added |
| J. Goldman & Co LP | 93,574 | $1.62M | 0.05% | +93,574 | New |
| Rhenman & Partners Asset Management AB | 93,250 | $1.61M | 0.20% | +65,000+230.1% | Added |
| Price T Rowe Associates Inc | 92,151 | $1.60M | 0.00% | +1,451+1.6% | Added |
| State Board of Administration of Florida Retirement System | 91,408 | $1.58M | 0.00% | −410−0.4% | Reduced |
| Natixis | 90,666 | $1.57M | 0.01% | −564,361−86.2% | Reduced |
| California State Teachers Retirement System | 87,929 | $1.52M | 0.00% | +28,151+47.1% | Added |
| HighVista Strategies LLC | 86,663 | $1.50M | 0.55% | −22,051−20.3% | Reduced |
| Rock Springs Capital Management LP | 84,300 | $1.46M | 0.09% | +4,300+5.4% | Added |
| Schonfeld Strategic Advisors LLC | 83,916 | $1.45M | 0.01% | −97,484−53.7% | Reduced |
| Walleye Capital LLC | 81,270 | $1.41M | 0.01% | −236,172−74.4% | Reduced |