Apellis Pharmaceuticals, Inc.
APLSDelisted- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001492422
Apellis Pharmaceuticals, Inc. was delisted in 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.
13F holders, Q3 2025
Institutional positions in Apellis Pharmaceuticals, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 273
- +31 vs. Q2 2025
- Shares held
- 122.3M
- −5.96M (−4.6%) vs. Q2 2025
- Total value
- $2.77B
- +$549.5M (+24.7%) vs. Q2 2025
- New holders
- 61
- 92 more added
- Sold out
- 30
- 91 more reduced
5 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1 | $10.2K |
| Q1 2026 | 324 | $5.56B |
| Q4 2025 | 280 | $3.17B |
| Q3 2025 | 273 | $2.77B |
| Q2 2025 | 247 | $2.29B |
| Q1 2025 | 255 | $2.80B |
| Q4 2024 | 260 | $4.05B |
| Q3 2024 | 265 | $3.52B |
| Q2 2024 | 263 | $4.56B |
| Q1 2024 | 302 | $6.97B |
| Q4 2023 | 284 | $7.16B |
| Q3 2023 | 256 | $4.34B |
| Q2 2023 | 317 | $9.81B |
| Q1 2023 | 282 | $7.49B |
| Q4 2022 | 244 | $5.26B |
| Q3 2022 | 250 | $6.67B |
| Q2 2022 | 212 | $4.15B |
| Q1 2022 | 212 | $4.62B |
| Q4 2021 | 187 | $3.91B |
| Q3 2021 | 181 | $2.29B |
| Q2 2021 | 205 | $4.13B |
| Q1 2021 | 175 | $2.80B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Avoro Capital Advisors LLC | 12,222,222 | $276.6M | 3.58% | 00.0% | Unchanged |
| Vanguard Group Inc | 9,987,394 | $226.0M | 0.00% | −167,357−1.6% | Reduced |
| Morgan Stanley | 9,643,248 | $218.2M | 0.01% | −108,953−1.1% | Reduced |
| Wellington Management Group LLP | 9,290,960 | $210.3M | 0.04% | +313,998+3.5% | Added |
| Deep Track Capital, LP | 8,000,382 | $181.0M | 5.05% | +1,000,382+14.3% | Added |
| BlackRock, Inc. | 6,268,465 | $141.9M | 0.00% | −136,534−2.1% | Reduced |
| AQR Capital Management LLC | 4,487,354 | $101.5M | 0.07% | −1,489,060−24.9% | Reduced |
| Jennison Associates LLC | 4,348,055 | $98.4M | 0.06% | +1,686,232+63.3% | Added |
| State Street Corp | 4,037,644 | $91.4M | 0.00% | +474,923+13.3% | Added |
| EcoR1 Capital, LLC | 3,447,156 | $78.0M | 3.74% | −8,448,652−71.0% | Reduced |
| UBS Group AG | 3,429,905 | $77.6M | 0.02% | −1,305,406−27.6% | Reduced |
| Suvretta Capital Management, LLC | 2,878,000 | $65.1M | 1.97% | 00.0% | Unchanged |
| Polar Capital Holdings Plc | 2,650,230 | $60.0M | 0.29% | +1,298,055+96.0% | Added |
| Siren, L.L.C. | 2,578,396 | $58.3M | 2.28% | 00.0% | Unchanged |
| OrbiMed Advisors LLC | 2,323,368 | $52.6M | 1.26% | +841,068+56.7% | Added |
| Geode Capital Management, LLC | 2,072,913 | $46.9M | 0.00% | +77,642+3.9% | Added |
| Amundi | 1,493,678 | $36.4M | 0.01% | −110,427−6.9% | Reduced |
| Deutsche Bank AG | 1,504,457 | $34.0M | 0.01% | +8,161+0.5% | Added |
| Bank of America Corp | 1,477,525 | $33.4M | 0.00% | −949,103−39.1% | Reduced |
| Bank of Nova Scotia | 1,456,225 | $33.0M | 0.06% | +861,413+144.8% | Added |
| Millennium Management LLC | 1,343,726 | $30.4M | 0.02% | +1,141,274+563.7% | Added |
| ING Groep NV | 1,174,500 | $26.6M | 0.14% | +866,200+281.0% | Added |
| Voloridge Investment Management, LLC | 992,269 | $22.5M | 0.08% | +523,559+111.7% | Added |
| BNP Paribas Arbitrage, SA | 972,474 | $22.0M | 0.02% | −325,985−25.1% | Reduced |
| Octagon Capital Advisors LP | 903,500 | $20.4M | 3.19% | 00.0% | Unchanged |
| Kynam Capital Management, LP | 808,607 | $18.3M | 1.36% | +808,607 | New |
| Renaissance Technologies LLC | 722,895 | $16.4M | 0.02% | +711,907+6,478.9% | Added |
| Ameriprise Financial Inc | 717,703 | $16.2M | 0.00% | −32,458−4.3% | Reduced |
| Nuveen, LLC | 665,048 | $15.1M | 0.00% | +195,795+41.7% | Added |
| Charles Schwab Investment Management Inc | 647,082 | $14.6M | 0.00% | −342,061−34.6% | Reduced |
| Los Angeles Capital Management LLC | 620,790 | $14.0M | 0.05% | +620,790 | New |
| Trexquant Investment LP | 586,939 | $13.3M | 0.14% | +259,518+79.3% | Added |
| Citadel Advisors LLC | 586,452 | $13.3M | 0.01% | +143,892+32.5% | Added |
| Ossiam | 555,953 | $12.6M | 0.16% | 00.0% | Unchanged |
| Northern Trust Corp | 549,248 | $12.4M | 0.00% | +23,366+4.4% | Added |
| Woodline Partners LP | 542,981 | $12.3M | 0.06% | +12,058+2.3% | Added |
| D. E. Shaw & Co., Inc. | 456,791 | $10.3M | 0.01% | +205,722+81.9% | Added |
| Ikarian Capital, LLC | 451,902 | $10.2M | 2.07% | +376,902+502.5% | Added |
| Citigroup Inc | 444,972 | $10.1M | 0.01% | +306,521+221.4% | Added |
| Hudson Bay Capital Management LP | 418,500 | $9.47M | 0.06% | −56,500−11.9% | Reduced |
| SG Americas Securities, LLC | 417,392 | $9.45M | 0.03% | +372,289+825.4% | Added |
| Marshall Wace, LLP | 396,735 | $8.98M | 0.01% | −2,308,102−85.3% | Reduced |
| Pictet Asset Management Holding SA | 363,450 | $8.23M | 0.01% | +15,101+4.3% | Added |
| HRT Financial LP | 353,649 | $8.00M | 0.03% | +246,449+229.9% | Added |
| Susquehanna International Group, LLP | 313,884 | $7.10M | 0.01% | −14,842−4.5% | Reduced |
| Caption Management, LLC | 305,000 | $6.90M | 0.40% | +74,112+32.1% | Added |
| Cubist Systematic Strategies, LLC | 299,783 | $6.78M | 0.10% | +299,783 | New |
| Ieq Capital, LLC | 296,784 | $6.72M | 0.02% | −50,139−14.5% | Reduced |
| Jane Street Group, LLC | 293,199 | $6.64M | 0.01% | +47,000+19.1% | Added |
| 683 Capital Management, LLC | 288,000 | $6.52M | 0.59% | −122,000−29.8% | Reduced |
| J. Goldman & Co LP | 283,153 | $6.41M | 0.24% | +189,579+202.6% | Added |
| Jump Financial, LLC | 277,648 | $6.28M | 0.08% | −281,020−50.3% | Reduced |
| Barclays PLC | 269,527 | $6.10M | 0.00% | −4,385−1.6% | Reduced |
| Two Sigma Investments, LP | 252,068 | $5.70M | 0.01% | −154,845−38.1% | Reduced |
| Jefferies Financial Group Inc. | 251,555 | $5.69M | 0.05% | −326,650−56.5% | Reduced |
| Integral Health Asset Management, LLC | 250,000 | $5.66M | 0.41% | +250,000 | New |
| Bank of New York Mellon Corp | 248,194 | $5.62M | 0.00% | +4,867+2.0% | Added |
| Readystate Asset Management LP | 241,977 | $5.48M | 0.27% | +241,977 | New |
| Rhenman & Partners Asset Management AB | 232,250 | $5.26M | 0.58% | +139,000+149.1% | Added |
| Point72 Asset Management, L.P. | 217,071 | $4.91M | 0.01% | +217,071 | New |
| Canada Pension Plan Investment Board | 217,000 | $4.91M | 0.00% | −119,800−35.6% | Reduced |
| Fiduciary Trust Co | 198,179 | $4.48M | 0.05% | −4,357−2.2% | Reduced |
| ExodusPoint Capital Management, LP | 194,758 | $4.41M | 0.06% | +194,758 | New |
| Silvercrest Asset Management Group LLC | 190,526 | $4.31M | 0.03% | +190,526 | New |
| Invesco Ltd. | 183,016 | $4.14M | 0.00% | +16,881+10.2% | Added |
| Boothbay Fund Management, LLC | 179,226 | $4.06M | 0.10% | +156,229+679.3% | Added |
| Schroder Investment Management Group | 173,087 | $3.92M | 0.00% | −312,528−64.4% | Reduced |
| Voya Investment Management LLC | 172,934 | $3.91M | 0.00% | +22,341+14.8% | Added |
| Rafferty Asset Management, LLC | 168,352 | $3.81M | 0.01% | +24,500+17.0% | Added |
| UBS Asset Management Americas Inc | 167,464 | $3.79M | 0.00% | −134,475−44.5% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 163,813 | $3.71M | 0.09% | −462−0.3% | Reduced |
| Bank of Montreal | 160,306 | $3.63M | 0.00% | +693+0.4% | Added |
| EFG Asset Management (North America) Corp. | 155,399 | $3.52M | 0.45% | +50,375+48.0% | Added |
| SEI Investments Co | 155,122 | $3.51M | 0.00% | +132,763+593.8% | Added |
| Swiss National Bank | 146,200 | $3.31M | 0.00% | +2,400+1.7% | Added |
| California Public Employees Retirement System | 146,188 | $3.31M | 0.00% | +11,551+8.6% | Added |
| Royal Bank of Canada | 146,207 | $3.31M | 0.00% | −651,378−81.7% | Reduced |
| HighVista Strategies LLC | 145,729 | $3.30M | 0.81% | +59,066+68.2% | Added |
| Walleye Capital LLC | 142,158 | $3.22M | 0.03% | +60,888+74.9% | Added |
| Aquatic Capital Management LLC | 130,828 | $2.96M | 0.05% | −45,876−26.0% | Reduced |
| Edgestream Partners, L.P. | 129,751 | $2.94M | 0.09% | −88,641−40.6% | Reduced |
| Cerity Partners LLC | 128,110 | $2.90M | 0.00% | +13,365+11.6% | Added |
| Gotham Asset Management, LLC | 127,158 | $2.88M | 0.01% | +7,929+6.7% | Added |
| Goldman Sachs Group Inc | 124,373 | $2.81M | 0.00% | −91,626−42.4% | Reduced |
| Qube Research & Technologies Ltd | 120,003 | $2.72M | 0.00% | +120,003 | New |
| Rhumbline Advisers | 117,429 | $2.66M | 0.00% | −4,573−3.7% | Reduced |
| Steward Partners Investment Advisory, LLC | 114,088 | $2.58M | 0.01% | −26,887−19.1% | Reduced |
| Worldquant Millennium Advisors LLC | 111,979 | $2.53M | 0.01% | +111,979 | New |
| Algert Global LLC | 109,733 | $2.48M | 0.04% | −44,380−28.8% | Reduced |
| Simplify Asset Management Inc. | 106,888 | $2.42M | 0.05% | +106,888 | New |
| Price T Rowe Associates Inc | 97,940 | $2.22M | 0.00% | +5,789+6.3% | Added |
| State Board of Administration of Florida Retirement System | 95,595 | $2.16M | 0.00% | +4,187+4.6% | Added |
| CWM, LLC | 94,233 | $2.13M | 0.01% | −33,351−26.1% | Reduced |
| Legal & General Group Plc | 92,392 | $2.09M | 0.00% | −3,658−3.8% | Reduced |
| Rock Springs Capital Management LP | 92,000 | $2.08M | 0.12% | +7,700+9.1% | Added |
| Brevan Howard Capital Management LP | 91,021 | $2.06M | 0.03% | +91,021 | New |
| Wealth Enhancement Advisory Services, LLC | 77,508 | $1.95M | 0.00% | −23,158−23.0% | Reduced |
| State of Wisconsin Investment Board | 85,761 | $1.94M | 0.00% | −8,643−9.2% | Reduced |
| SRS Capital Advisors, Inc. | 82,067 | $1.86M | 0.03% | +82,067 | New |
| Alliancebernstein L.P. | 80,605 | $1.82M | 0.00% | +48,676+152.5% | Added |