Apellis Pharmaceuticals, Inc.
APLS已下市- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0001492422
Apellis Pharmaceuticals, Inc. 已在 2026 年下市；內部人最後一份 Form 4 在 2026/5/14 申報；2026 年第 1 季末有 324 家機構在 13F 申報持有，市值合計 $55.6 億；大師中只有索羅斯基金管理持有。
2025 年第 3 季 13F 持有人
Apellis Pharmaceuticals, Inc. 在 2025/9/30 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 273
- 較 2025 年第 2 季 +31 家
- 持有股數
- 1.22 億
- 較 2025 年第 2 季 −595.7 萬 (−4.6%)
- 總市值
- $27.7 億
- 較 2025 年第 2 季 +$5.49 億 (+24.7%)
- 新進機構
- 61
- 另有 92 家加碼
- 清倉機構
- 30
- 另有 91 家減碼
另有 5 家機構在 2025 年第 2 季持有、還沒有申報 2025 年第 3 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 APLS 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 1 | $1.02 萬 |
| 2026 年第 1 季 | 324 | $55.6 億 |
| 2025 年第 4 季 | 280 | $31.7 億 |
| 2025 年第 3 季 | 273 | $27.7 億 |
| 2025 年第 2 季 | 247 | $22.9 億 |
| 2025 年第 1 季 | 255 | $28.0 億 |
| 2024 年第 4 季 | 260 | $40.5 億 |
| 2024 年第 3 季 | 265 | $35.2 億 |
| 2024 年第 2 季 | 263 | $45.6 億 |
| 2024 年第 1 季 | 302 | $69.7 億 |
| 2023 年第 4 季 | 284 | $71.6 億 |
| 2023 年第 3 季 | 256 | $43.4 億 |
| 2023 年第 2 季 | 317 | $98.1 億 |
| 2023 年第 1 季 | 282 | $74.9 億 |
| 2022 年第 4 季 | 244 | $52.6 億 |
| 2022 年第 3 季 | 250 | $66.7 億 |
| 2022 年第 2 季 | 212 | $41.5 億 |
| 2022 年第 1 季 | 212 | $46.2 億 |
| 2021 年第 4 季 | 187 | $39.1 億 |
| 2021 年第 3 季 | 181 | $22.9 億 |
| 2021 年第 2 季 | 205 | $41.3 億 |
| 2021 年第 1 季 | 175 | $28.0 億 |
2025 年第 3 季持有機構
每家機構持有 Apellis Pharmaceuticals, Inc. 的股數、市值與佔組合比重；股數變化跟 2025 年第 2 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Avoro Capital Advisors LLC | 12,222,222 | $2.77 億 | 3.58% | 00.0% | 不變 |
| Vanguard Group Inc | 9,987,394 | $2.26 億 | 0.00% | −167,357−1.6% | 減碼 |
| Morgan Stanley | 9,643,248 | $2.18 億 | 0.01% | −108,953−1.1% | 減碼 |
| Wellington Management Group LLP | 9,290,960 | $2.10 億 | 0.04% | +313,998+3.5% | 加碼 |
| Deep Track Capital, LP | 8,000,382 | $1.81 億 | 5.05% | +1,000,382+14.3% | 加碼 |
| BlackRock, Inc. | 6,268,465 | $1.42 億 | 0.00% | −136,534−2.1% | 減碼 |
| AQR Capital Management LLC | 4,487,354 | $1.02 億 | 0.07% | −1,489,060−24.9% | 減碼 |
| Jennison Associates LLC | 4,348,055 | $9,840 萬 | 0.06% | +1,686,232+63.3% | 加碼 |
| State Street Corp | 4,037,644 | $9,137 萬 | 0.00% | +474,923+13.3% | 加碼 |
| EcoR1 Capital, LLC | 3,447,156 | $7,801 萬 | 3.74% | −8,448,652−71.0% | 減碼 |
| UBS Group AG | 3,429,905 | $7,762 萬 | 0.02% | −1,305,406−27.6% | 減碼 |
| Suvretta Capital Management, LLC | 2,878,000 | $6,513 萬 | 1.97% | 00.0% | 不變 |
| Polar Capital Holdings Plc | 2,650,230 | $5,997 萬 | 0.29% | +1,298,055+96.0% | 加碼 |
| Siren, L.L.C. | 2,578,396 | $5,835 萬 | 2.28% | 00.0% | 不變 |
| OrbiMed Advisors LLC | 2,323,368 | $5,258 萬 | 1.26% | +841,068+56.7% | 加碼 |
| Geode Capital Management, LLC | 2,072,913 | $4,692 萬 | 0.00% | +77,642+3.9% | 加碼 |
| Amundi | 1,493,678 | $3,639 萬 | 0.01% | −110,427−6.9% | 減碼 |
| Deutsche Bank AG | 1,504,457 | $3,405 萬 | 0.01% | +8,161+0.5% | 加碼 |
| Bank of America Corp | 1,477,525 | $3,344 萬 | 0.00% | −949,103−39.1% | 減碼 |
| Bank of Nova Scotia | 1,456,225 | $3,295 萬 | 0.06% | +861,413+144.8% | 加碼 |
| Millennium Management LLC | 1,343,726 | $3,041 萬 | 0.02% | +1,141,274+563.7% | 加碼 |
| ING Groep NV | 1,174,500 | $2,658 萬 | 0.14% | +866,200+281.0% | 加碼 |
| Voloridge Investment Management, LLC | 992,269 | $2,246 萬 | 0.08% | +523,559+111.7% | 加碼 |
| BNP Paribas Arbitrage, SA | 972,474 | $2,201 萬 | 0.02% | −325,985−25.1% | 減碼 |
| Octagon Capital Advisors LP | 903,500 | $2,045 萬 | 3.19% | 00.0% | 不變 |
| Kynam Capital Management, LP | 808,607 | $1,830 萬 | 1.36% | +808,607 | 新進 |
| Renaissance Technologies LLC | 722,895 | $1,636 萬 | 0.02% | +711,907+6,478.9% | 加碼 |
| Ameriprise Financial Inc | 717,703 | $1,624 萬 | 0.00% | −32,458−4.3% | 減碼 |
| Nuveen, LLC | 665,048 | $1,505 萬 | 0.00% | +195,795+41.7% | 加碼 |
| Charles Schwab Investment Management Inc | 647,082 | $1,464 萬 | 0.00% | −342,061−34.6% | 減碼 |
| Los Angeles Capital Management LLC | 620,790 | $1,405 萬 | 0.05% | +620,790 | 新進 |
| Trexquant Investment LP | 586,939 | $1,328 萬 | 0.14% | +259,518+79.3% | 加碼 |
| Citadel Advisors LLC | 586,452 | $1,327 萬 | 0.01% | +143,892+32.5% | 加碼 |
| Ossiam | 555,953 | $1,258 萬 | 0.16% | 00.0% | 不變 |
| Northern Trust Corp | 549,248 | $1,243 萬 | 0.00% | +23,366+4.4% | 加碼 |
| Woodline Partners LP | 542,981 | $1,229 萬 | 0.06% | +12,058+2.3% | 加碼 |
| D. E. Shaw & Co., Inc. | 456,791 | $1,034 萬 | 0.01% | +205,722+81.9% | 加碼 |
| Ikarian Capital, LLC | 451,902 | $1,023 萬 | 2.07% | +376,902+502.5% | 加碼 |
| Citigroup Inc | 444,972 | $1,007 萬 | 0.01% | +306,521+221.4% | 加碼 |
| Hudson Bay Capital Management LP | 418,500 | $947.1 萬 | 0.06% | −56,500−11.9% | 減碼 |
| SG Americas Securities, LLC | 417,392 | $944.6 萬 | 0.03% | +372,289+825.4% | 加碼 |
| Marshall Wace, LLP | 396,735 | $897.8 萬 | 0.01% | −2,308,102−85.3% | 減碼 |
| Pictet Asset Management Holding SA | 363,450 | $823.2 萬 | 0.01% | +15,101+4.3% | 加碼 |
| HRT Financial LP | 353,649 | $800.3 萬 | 0.03% | +246,449+229.9% | 加碼 |
| Susquehanna International Group, LLP | 313,884 | $710.3 萬 | 0.01% | −14,842−4.5% | 減碼 |
| Caption Management, LLC | 305,000 | $690.2 萬 | 0.40% | +74,112+32.1% | 加碼 |
| Cubist Systematic Strategies, LLC | 299,783 | $678.4 萬 | 0.10% | +299,783 | 新進 |
| Ieq Capital, LLC | 296,784 | $671.6 萬 | 0.02% | −50,139−14.5% | 減碼 |
| Jane Street Group, LLC | 293,199 | $663.5 萬 | 0.01% | +47,000+19.1% | 加碼 |
| 683 Capital Management, LLC | 288,000 | $651.7 萬 | 0.59% | −122,000−29.8% | 減碼 |
| J. Goldman & Co LP | 283,153 | $640.8 萬 | 0.24% | +189,579+202.6% | 加碼 |
| Jump Financial, LLC | 277,648 | $628.3 萬 | 0.08% | −281,020−50.3% | 減碼 |
| Barclays PLC | 269,527 | $609.9 萬 | 0.00% | −4,385−1.6% | 減碼 |
| Two Sigma Investments, LP | 252,068 | $570.4 萬 | 0.01% | −154,845−38.1% | 減碼 |
| Jefferies Financial Group Inc. | 251,555 | $569.3 萬 | 0.05% | −326,650−56.5% | 減碼 |
| Integral Health Asset Management, LLC | 250,000 | $565.8 萬 | 0.41% | +250,000 | 新進 |
| Bank of New York Mellon Corp | 248,194 | $561.7 萬 | 0.00% | +4,867+2.0% | 加碼 |
| Readystate Asset Management LP | 241,977 | $547.6 萬 | 0.27% | +241,977 | 新進 |
| Rhenman & Partners Asset Management AB | 232,250 | $525.6 萬 | 0.58% | +139,000+149.1% | 加碼 |
| Point72 Asset Management, L.P. | 217,071 | $491.2 萬 | 0.01% | +217,071 | 新進 |
| Canada Pension Plan Investment Board | 217,000 | $491.1 萬 | 0.00% | −119,800−35.6% | 減碼 |
| Fiduciary Trust Co | 198,179 | $448.5 萬 | 0.05% | −4,357−2.2% | 減碼 |
| ExodusPoint Capital Management, LP | 194,758 | $440.7 萬 | 0.06% | +194,758 | 新進 |
| Silvercrest Asset Management Group LLC | 190,526 | $431.2 萬 | 0.03% | +190,526 | 新進 |
| Invesco Ltd. | 183,016 | $414.2 萬 | 0.00% | +16,881+10.2% | 加碼 |
| Boothbay Fund Management, LLC | 179,226 | $405.6 萬 | 0.10% | +156,229+679.3% | 加碼 |
| Schroder Investment Management Group | 173,087 | $392.0 萬 | 0.00% | −312,528−64.4% | 減碼 |
| Voya Investment Management LLC | 172,934 | $391.3 萬 | 0.00% | +22,341+14.8% | 加碼 |
| Rafferty Asset Management, LLC | 168,352 | $381.0 萬 | 0.01% | +24,500+17.0% | 加碼 |
| UBS Asset Management Americas Inc | 167,464 | $379.0 萬 | 0.00% | −134,475−44.5% | 減碼 |
| Y-Intercept (Hong Kong) Ltd | 163,813 | $370.7 萬 | 0.09% | −462−0.3% | 減碼 |
| Bank of Montreal | 160,306 | $362.8 萬 | 0.00% | +693+0.4% | 加碼 |
| EFG Asset Management (North America) Corp. | 155,399 | $351.7 萬 | 0.45% | +50,375+48.0% | 加碼 |
| SEI Investments Co | 155,122 | $351.0 萬 | 0.00% | +132,763+593.8% | 加碼 |
| Swiss National Bank | 146,200 | $330.9 萬 | 0.00% | +2,400+1.7% | 加碼 |
| California Public Employees Retirement System | 146,188 | $330.8 萬 | 0.00% | +11,551+8.6% | 加碼 |
| Royal Bank of Canada | 146,207 | $330.8 萬 | 0.00% | −651,378−81.7% | 減碼 |
| HighVista Strategies LLC | 145,729 | $329.8 萬 | 0.81% | +59,066+68.2% | 加碼 |
| Walleye Capital LLC | 142,158 | $321.7 萬 | 0.03% | +60,888+74.9% | 加碼 |
| Aquatic Capital Management LLC | 130,828 | $296.1 萬 | 0.05% | −45,876−26.0% | 減碼 |
| Edgestream Partners, L.P. | 129,751 | $293.6 萬 | 0.09% | −88,641−40.6% | 減碼 |
| Cerity Partners LLC | 128,110 | $289.9 萬 | 0.00% | +13,365+11.6% | 加碼 |
| Gotham Asset Management, LLC | 127,158 | $287.8 萬 | 0.01% | +7,929+6.7% | 加碼 |
| Goldman Sachs Group Inc | 124,373 | $281.5 萬 | 0.00% | −91,626−42.4% | 減碼 |
| Qube Research & Technologies Ltd | 120,003 | $271.6 萬 | 0.00% | +120,003 | 新進 |
| Rhumbline Advisers | 117,429 | $265.7 萬 | 0.00% | −4,573−3.7% | 減碼 |
| Steward Partners Investment Advisory, LLC | 114,088 | $258.2 萬 | 0.01% | −26,887−19.1% | 減碼 |
| Worldquant Millennium Advisors LLC | 111,979 | $253.4 萬 | 0.01% | +111,979 | 新進 |
| Algert Global LLC | 109,733 | $248.3 萬 | 0.04% | −44,380−28.8% | 減碼 |
| Simplify Asset Management Inc. | 106,888 | $241.9 萬 | 0.05% | +106,888 | 新進 |
| Price T Rowe Associates Inc | 97,940 | $221.7 萬 | 0.00% | +5,789+6.3% | 加碼 |
| State Board of Administration of Florida Retirement System | 95,595 | $216.3 萬 | 0.00% | +4,187+4.6% | 加碼 |
| CWM, LLC | 94,233 | $213.2 萬 | 0.01% | −33,351−26.1% | 減碼 |
| Legal & General Group Plc | 92,392 | $209.1 萬 | 0.00% | −3,658−3.8% | 減碼 |
| Rock Springs Capital Management LP | 92,000 | $208.2 萬 | 0.12% | +7,700+9.1% | 加碼 |
| Brevan Howard Capital Management LP | 91,021 | $206.0 萬 | 0.03% | +91,021 | 新進 |
| Wealth Enhancement Advisory Services, LLC | 77,508 | $195.4 萬 | 0.00% | −23,158−23.0% | 減碼 |
| State of Wisconsin Investment Board | 85,761 | $194.1 萬 | 0.00% | −8,643−9.2% | 減碼 |
| SRS Capital Advisors, Inc. | 82,067 | $185.7 萬 | 0.03% | +82,067 | 新進 |
| Alliancebernstein L.P. | 80,605 | $182.4 萬 | 0.00% | +48,676+152.5% | 加碼 |