Apellis Pharmaceuticals, Inc.
APLS已下市- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0001492422
Apellis Pharmaceuticals, Inc. 已在 2026 年下市；內部人最後一份 Form 4 在 2026/5/14 申報；2026 年第 1 季末有 324 家機構在 13F 申報持有，市值合計 $55.6 億；大師中只有索羅斯基金管理持有。
2025 年第 4 季 13F 持有人
Apellis Pharmaceuticals, Inc. 在 2025/12/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 280
- 較 2025 年第 3 季 +14 家
- 持有股數
- 1.26 億
- 較 2025 年第 3 季 +464.5 萬 (+3.8%)
- 總市值
- $31.7 億
- 較 2025 年第 3 季 +$4.15 億 (+15.0%)
- 新進機構
- 61
- 另有 89 家加碼
- 清倉機構
- 47
- 另有 102 家減碼
另有 7 家機構在 2025 年第 3 季持有、還沒有申報 2025 年第 4 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 APLS 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 1 | $1.02 萬 |
| 2026 年第 1 季 | 324 | $55.6 億 |
| 2025 年第 4 季 | 280 | $31.7 億 |
| 2025 年第 3 季 | 273 | $27.7 億 |
| 2025 年第 2 季 | 247 | $22.9 億 |
| 2025 年第 1 季 | 255 | $28.0 億 |
| 2024 年第 4 季 | 260 | $40.5 億 |
| 2024 年第 3 季 | 265 | $35.2 億 |
| 2024 年第 2 季 | 263 | $45.6 億 |
| 2024 年第 1 季 | 302 | $69.7 億 |
| 2023 年第 4 季 | 284 | $71.6 億 |
| 2023 年第 3 季 | 256 | $43.4 億 |
| 2023 年第 2 季 | 317 | $98.1 億 |
| 2023 年第 1 季 | 282 | $74.9 億 |
| 2022 年第 4 季 | 244 | $52.6 億 |
| 2022 年第 3 季 | 250 | $66.7 億 |
| 2022 年第 2 季 | 212 | $41.5 億 |
| 2022 年第 1 季 | 212 | $46.2 億 |
| 2021 年第 4 季 | 187 | $39.1 億 |
| 2021 年第 3 季 | 181 | $22.9 億 |
| 2021 年第 2 季 | 205 | $41.3 億 |
| 2021 年第 1 季 | 175 | $28.0 億 |
2025 年第 4 季持有機構
每家機構持有 Apellis Pharmaceuticals, Inc. 的股數、市值與佔組合比重；股數變化跟 2025 年第 3 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Wellington Management Group LLP | 12,721,352 | $3.20 億 | 0.06% | +3,430,392+36.9% | 加碼 |
| Avoro Capital Advisors LLC | 12,222,222 | $3.07 億 | 3.02% | 00.0% | 不變 |
| Vanguard Group Inc | 10,674,865 | $2.68 億 | 0.00% | +687,471+6.9% | 加碼 |
| Morgan Stanley | 9,173,004 | $2.30 億 | 0.01% | −470,244−4.9% | 減碼 |
| Deep Track Capital, LP | 7,750,000 | $1.95 億 | 4.44% | −250,382−3.1% | 減碼 |
| RTW Investments, LP | 7,666,764 | $1.93 億 | 1.93% | +7,666,764 | 新進 |
| BlackRock, Inc. | 6,260,113 | $1.57 億 | 0.00% | −8,352−0.1% | 減碼 |
| State Street Corp | 4,613,446 | $1.16 億 | 0.00% | +575,802+14.3% | 加碼 |
| UBS Group AG | 4,186,222 | $1.05 億 | 0.02% | +756,317+22.1% | 加碼 |
| Suvretta Capital Management, LLC | 4,139,426 | $1.04 億 | 2.59% | +1,261,426+43.8% | 加碼 |
| Polar Capital Holdings Plc | 3,706,510 | $9,311 萬 | 0.43% | +1,056,280+39.9% | 加碼 |
| Siren, L.L.C. | 2,578,396 | $6,477 萬 | 1.93% | 00.0% | 不變 |
| OrbiMed Advisors LLC | 2,429,868 | $6,104 萬 | 1.25% | +106,500+4.6% | 加碼 |
| AQR Capital Management LLC | 2,276,687 | $5,719 萬 | 0.03% | −2,210,667−49.3% | 減碼 |
| Geode Capital Management, LLC | 2,025,669 | $5,090 萬 | 0.00% | −47,244−2.3% | 減碼 |
| Jennison Associates LLC | 1,504,299 | $3,779 萬 | 0.02% | −2,843,756−65.4% | 減碼 |
| Deutsche Bank AG | 1,385,263 | $3,480 萬 | 0.01% | −119,194−7.9% | 減碼 |
| Norges Bank | 1,198,444 | $3,010 萬 | 0.00% | +1,198,444 | 新進 |
| Hudson Bay Capital Management LP | 1,179,828 | $2,964 萬 | 0.17% | +761,328+181.9% | 加碼 |
| Bank of Nova Scotia | 1,070,141 | $2,688 萬 | 0.04% | −386,084−26.5% | 減碼 |
| Marshall Wace, LLP | 990,848 | $2,489 萬 | 0.02% | +594,113+149.8% | 加碼 |
| Bank of America Corp | 956,773 | $2,403 萬 | 0.00% | −520,752−35.2% | 減碼 |
| Millennium Management LLC | 946,459 | $2,378 萬 | 0.02% | −397,267−29.6% | 減碼 |
| Kynam Capital Management, LP | 908,607 | $2,282 萬 | 1.49% | +100,000+12.4% | 加碼 |
| Los Angeles Capital Management LLC | 951,716 | $1,973 萬 | 0.07% | +330,926+53.3% | 加碼 |
| Northern Trust Corp | 696,521 | $1,750 萬 | 0.00% | +147,273+26.8% | 加碼 |
| Nuveen, LLC | 681,819 | $1,713 萬 | 0.00% | +16,771+2.5% | 加碼 |
| Citadel Advisors LLC | 648,229 | $1,628 萬 | 0.01% | +61,777+10.5% | 加碼 |
| Charles Schwab Investment Management Inc | 644,445 | $1,619 萬 | 0.00% | −2,637−0.4% | 減碼 |
| Renaissance Technologies LLC | 633,058 | $1,590 萬 | 0.02% | −89,837−12.4% | 減碼 |
| Citigroup Inc | 622,158 | $1,563 萬 | 0.01% | +177,186+39.8% | 加碼 |
| Point72 Asset Management, L.P. | 597,672 | $1,501 萬 | 0.02% | +380,601+175.3% | 加碼 |
| Ameriprise Financial Inc | 589,597 | $1,481 萬 | 0.00% | −128,106−17.8% | 減碼 |
| SG Americas Securities, LLC | 567,046 | $1,424 萬 | 0.02% | +149,654+35.9% | 加碼 |
| Two Sigma Investments, LP | 562,361 | $1,413 萬 | 0.02% | +310,293+123.1% | 加碼 |
| BNP Paribas Arbitrage, SA | 557,591 | $1,401 萬 | 0.01% | −414,883−42.7% | 減碼 |
| Woodline Partners LP | 542,981 | $1,364 萬 | 0.05% | 00.0% | 不變 |
| Simplify Asset Management Inc. | 538,008 | $1,351 萬 | 0.22% | +431,120+403.3% | 加碼 |
| Susquehanna International Group, LLP | 533,909 | $1,341 萬 | 0.02% | +220,025+70.1% | 加碼 |
| First Trust Advisors LP | 495,947 | $1,246 萬 | 0.01% | +495,947 | 新進 |
| Voloridge Investment Management, LLC | 461,186 | $1,158 萬 | 0.04% | −531,083−53.5% | 減碼 |
| D. E. Shaw & Co., Inc. | 449,676 | $1,130 萬 | 0.01% | −7,115−1.6% | 減碼 |
| Ossiam | 431,779 | $1,085 萬 | 0.22% | −124,174−22.3% | 減碼 |
| Pictet Asset Management Holding SA | 390,884 | $983.8 萬 | 0.01% | +27,434+7.5% | 加碼 |
| Rhenman & Partners Asset Management AB | 374,450 | $940.6 萬 | 0.88% | +142,200+61.2% | 加碼 |
| Schroder Investment Management Group | 329,134 | $830.7 萬 | 0.01% | +156,047+90.2% | 加碼 |
| 683 Capital Management, LLC | 330,000 | $829.0 萬 | 0.69% | +42,000+14.6% | 加碼 |
| Granite Investment Partners, LLC | 327,094 | $821.7 萬 | 0.49% | +327,094 | 新進 |
| J. Goldman & Co LP | 285,992 | $718.4 萬 | 0.28% | +2,839+1.0% | 加碼 |
| Bank of New York Mellon Corp | 271,925 | $683.1 萬 | 0.00% | +23,731+9.6% | 加碼 |
| Natixis | 257,268 | $646.3 萬 | 0.03% | +205,029+392.5% | 加碼 |
| Caption Management, LLC | 254,563 | $639.5 萬 | 0.28% | −50,437−16.5% | 減碼 |
| Sphera Funds Management Ltd. | 250,961 | $630.4 萬 | 1.32% | +187,301+294.2% | 加碼 |
| Janus Henderson Group PLC | 230,320 | $578.6 萬 | 0.00% | +195,908+569.3% | 加碼 |
| Invesco Ltd. | 225,976 | $567.7 萬 | 0.00% | +42,960+23.5% | 加碼 |
| Canada Pension Plan Investment Board | 222,200 | $558.2 萬 | 0.00% | +5,200+2.4% | 加碼 |
| Tudor Investment Corp Et Al | 215,000 | $540.1 萬 | 0.03% | +215,000 | 新進 |
| Acadian Asset Management LLC | 205,986 | $516.5 萬 | 0.01% | +193,533+1,554.1% | 加碼 |
| Integral Health Asset Management, LLC | 200,000 | $502.4 萬 | 0.25% | −50,000−20.0% | 減碼 |
| Trexquant Investment LP | 194,592 | $488.8 萬 | 0.04% | −392,347−66.8% | 減碼 |
| Jump Financial, LLC | 193,876 | $487.0 萬 | 0.06% | −83,772−30.2% | 減碼 |
| HRT Financial LP | 192,488 | $483.5 萬 | 0.02% | −161,161−45.6% | 減碼 |
| Squarepoint Ops LLC | 192,156 | $482.7 萬 | 0.01% | +139,322+263.7% | 加碼 |
| Apis Capital Advisors, LLC | 192,000 | $482.3 萬 | 0.84% | +192,000 | 新進 |
| Silvercrest Asset Management Group LLC | 190,759 | $479.2 萬 | 0.03% | +233+0.1% | 加碼 |
| Goldman Sachs Group Inc | 189,205 | $475.3 萬 | 0.00% | +64,832+52.1% | 加碼 |
| Barclays PLC | 187,712 | $471.5 萬 | 0.00% | −81,815−30.4% | 減碼 |
| California Public Employees Retirement System | 186,328 | $468.1 萬 | 0.00% | +40,140+27.5% | 加碼 |
| Dimensional Fund Advisors LP | 180,925 | $454.5 萬 | 0.00% | +162,235+868.0% | 加碼 |
| Fiduciary Trust Co | 180,254 | $452.8 萬 | 0.05% | −17,925−9.0% | 減碼 |
| UBS Asset Management Americas Inc | 178,888 | $449.4 萬 | 0.00% | +11,424+6.8% | 加碼 |
| Bank of Montreal | 176,571 | $443.5 萬 | 0.00% | +16,265+10.1% | 加碼 |
| Rafferty Asset Management, LLC | 171,456 | $430.7 萬 | 0.01% | +3,104+1.8% | 加碼 |
| ExodusPoint Capital Management, LP | 171,156 | $429.9 萬 | 0.05% | −23,602−12.1% | 減碼 |
| Gotham Asset Management, LLC | 168,455 | $423.2 萬 | 0.02% | +41,297+32.5% | 加碼 |
| JPMorgan Chase & Co | 157,754 | $396.3 萬 | 0.00% | +104,238+194.8% | 加碼 |
| HighVista Strategies LLC | 150,776 | $378.7 萬 | 0.98% | +5,047+3.5% | 加碼 |
| Rock Springs Capital Management LP | 150,500 | $378.1 萬 | 0.19% | +58,500+63.6% | 加碼 |
| Swiss National Bank | 149,500 | $375.5 萬 | 0.00% | +3,300+2.3% | 加碼 |
| Man Group plc | 144,271 | $362.4 萬 | 0.01% | +77,069+114.7% | 加碼 |
| Bridgewater Associates, LP | 143,805 | $361.2 萬 | 0.01% | +143,805 | 新進 |
| DekaBank Deutsche Girozentrale | 55,000 | $349.7 萬 | 0.01% | 00.0% | 不變 |
| ING Groep NV | 139,000 | $349.2 萬 | 0.02% | −1,035,500−88.2% | 減碼 |
| Exome Asset Management LLC | 135,849 | $341.3 萬 | 1.69% | +135,849 | 新進 |
| Rhumbline Advisers | 116,917 | $293.7 萬 | 0.00% | −512−0.4% | 減碼 |
| Two Sigma Advisers, LP | 110,900 | $278.6 萬 | 0.01% | +110,900 | 新進 |
| Algert Global LLC | 109,733 | $275.6 萬 | 0.04% | 00.0% | 不變 |
| New York State Common Retirement Fund | 104,018 | $261.3 萬 | 0.00% | +55,181+113.0% | 加碼 |
| Wells Fargo & Company | 103,815 | $260.8 萬 | 0.00% | +101,352+4,115.0% | 加碼 |
| Alps Advisors Inc | 103,696 | $260.5 萬 | 0.02% | +40,881+65.1% | 加碼 |
| Edgestream Partners, L.P. | 97,443 | $244.8 萬 | 0.07% | −32,308−24.9% | 減碼 |
| Mackenzie Financial Corp | 96,211 | $242.4 萬 | 0.00% | +19,500+25.4% | 加碼 |
| State Board of Administration of Florida Retirement System | 96,125 | $241.5 萬 | 0.00% | +530+0.6% | 加碼 |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 95,755 | $240.5 萬 | 0.00% | +49,642+107.7% | 加碼 |
| Price T Rowe Associates Inc | 95,035 | $238.8 萬 | 0.00% | −2,905−3.0% | 減碼 |
| Royal Bank of Canada | 88,687 | $222.8 萬 | 0.00% | −57,520−39.3% | 減碼 |
| Winton Group Ltd | 86,653 | $217.7 萬 | 0.08% | +86,653 | 新進 |
| Legal & General Group Plc | 85,489 | $214.7 萬 | 0.00% | −6,903−7.5% | 減碼 |
| Steward Partners Investment Advisory, LLC | 81,698 | $205.2 萬 | 0.01% | −32,390−28.4% | 減碼 |
| Coppell Advisory Solutions LLC | 77,390 | $195.3 萬 | 0.19% | +77,390 | 新進 |