Apellis Pharmaceuticals, Inc.
APLSDelisted May 14, 2026- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001492422
Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.
13F holders, Q4 2025
Institutional positions in Apellis Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 280
- +13 vs. Q3 2025
- Shares held
- 126.4M
- +3.50M (+2.8%) vs. Q3 2025
- Total value
- $3.17B
- +$389.1M (+14.0%) vs. Q3 2025
- New holders
- 60
- 90 more added
- Sold out
- 47
- 102 more reduced
7 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1 | $10.2K |
| Q1 2026 | 324 | $5.56B |
| Q4 2025 | 280 | $3.17B |
| Q3 2025 | 274 | $2.80B |
| Q2 2025 | 247 | $2.28B |
| Q1 2025 | 255 | $2.80B |
| Q4 2024 | 260 | $4.04B |
| Q3 2024 | 267 | $3.41B |
| Q2 2024 | 263 | $4.43B |
| Q1 2024 | 302 | $6.65B |
| Q4 2023 | 284 | $6.82B |
| Q3 2023 | 256 | $4.34B |
| Q2 2023 | 317 | $9.71B |
| Q1 2023 | 282 | $7.28B |
| Q4 2022 | 244 | $5.20B |
| Q3 2022 | 250 | $6.66B |
| Q2 2022 | 212 | $4.15B |
| Q1 2022 | 212 | $4.62B |
| Q4 2021 | 187 | $3.83B |
| Q3 2021 | 181 | $2.29B |
| Q2 2021 | 205 | $4.08B |
| Q1 2021 | 175 | $2.80B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Wellington Management Group LLP | 12,721,352 | $319.6M | 0.06% | +3,430,392+36.9% | Added |
| Avoro Capital Advisors LLC | 12,222,222 | $307.0M | 3.02% | 00.0% | Unchanged |
| Vanguard Group Inc | 10,674,865 | $268.2M | 0.00% | +687,471+6.9% | Added |
| Morgan Stanley | 9,173,004 | $230.4M | 0.01% | −470,244−4.9% | Reduced |
| Deep Track Capital, LP | 7,750,000 | $194.7M | 4.44% | −250,382−3.1% | Reduced |
| RTW Investments, LP | 7,666,764 | $192.6M | 1.93% | +7,666,764 | New |
| BlackRock, Inc. | 6,260,113 | $157.3M | 0.00% | −8,352−0.1% | Reduced |
| State Street Corp | 4,613,446 | $115.9M | 0.00% | +575,802+14.3% | Added |
| UBS Group AG | 4,186,222 | $105.2M | 0.02% | +756,317+22.1% | Added |
| Suvretta Capital Management, LLC | 4,139,426 | $104.0M | 2.59% | +1,261,426+43.8% | Added |
| Polar Capital Holdings Plc | 3,706,510 | $93.1M | 0.43% | +1,056,280+39.9% | Added |
| Siren, L.L.C. | 2,578,396 | $64.8M | 1.93% | 00.0% | Unchanged |
| OrbiMed Advisors LLC | 2,429,868 | $61.0M | 1.25% | +106,500+4.6% | Added |
| AQR Capital Management LLC | 2,276,687 | $57.2M | 0.03% | −2,210,667−49.3% | Reduced |
| Geode Capital Management, LLC | 2,025,669 | $50.9M | 0.00% | −47,244−2.3% | Reduced |
| Jennison Associates LLC | 1,504,299 | $37.8M | 0.02% | −2,843,756−65.4% | Reduced |
| Deutsche Bank AG | 1,385,263 | $34.8M | 0.01% | −119,194−7.9% | Reduced |
| Norges Bank | 1,198,444 | $30.1M | 0.00% | +52,632+4.6% | Added |
| Hudson Bay Capital Management LP | 1,179,828 | $29.6M | 0.17% | +761,328+181.9% | Added |
| Bank of Nova Scotia | 1,070,141 | $26.9M | 0.04% | −386,084−26.5% | Reduced |
| Marshall Wace, LLP | 990,848 | $24.9M | 0.02% | +594,113+149.8% | Added |
| Bank of America Corp | 956,773 | $24.0M | 0.00% | −520,752−35.2% | Reduced |
| Millennium Management LLC | 946,459 | $23.8M | 0.02% | −397,267−29.6% | Reduced |
| Kynam Capital Management, LP | 908,607 | $22.8M | 1.49% | +100,000+12.4% | Added |
| Los Angeles Capital Management LLC | 951,716 | $19.7M | 0.07% | +330,926+53.3% | Added |
| Northern Trust Corp | 696,521 | $17.5M | 0.00% | +147,273+26.8% | Added |
| Nuveen, LLC | 681,819 | $17.1M | 0.00% | +16,771+2.5% | Added |
| Citadel Advisors LLC | 648,229 | $16.3M | 0.01% | +61,777+10.5% | Added |
| Charles Schwab Investment Management Inc | 644,445 | $16.2M | 0.00% | −2,637−0.4% | Reduced |
| Renaissance Technologies LLC | 633,058 | $15.9M | 0.02% | −89,837−12.4% | Reduced |
| Citigroup Inc | 622,158 | $15.6M | 0.01% | +177,186+39.8% | Added |
| Point72 Asset Management, L.P. | 597,672 | $15.0M | 0.02% | +380,601+175.3% | Added |
| Ameriprise Financial Inc | 589,597 | $14.8M | 0.00% | −128,106−17.8% | Reduced |
| SG Americas Securities, LLC | 567,046 | $14.2M | 0.02% | +149,654+35.9% | Added |
| Two Sigma Investments, LP | 562,361 | $14.1M | 0.02% | +310,293+123.1% | Added |
| BNP Paribas Arbitrage, SA | 557,591 | $14.0M | 0.01% | −414,883−42.7% | Reduced |
| Woodline Partners LP | 542,981 | $13.6M | 0.05% | 00.0% | Unchanged |
| Simplify Asset Management Inc. | 538,008 | $13.5M | 0.22% | +431,120+403.3% | Added |
| Susquehanna International Group, LLP | 533,909 | $13.4M | 0.02% | +220,025+70.1% | Added |
| First Trust Advisors LP | 495,947 | $12.5M | 0.01% | +495,947 | New |
| Voloridge Investment Management, LLC | 461,186 | $11.6M | 0.04% | −531,083−53.5% | Reduced |
| D. E. Shaw & Co., Inc. | 449,676 | $11.3M | 0.01% | −7,115−1.6% | Reduced |
| Ossiam | 431,779 | $10.8M | 0.22% | −124,174−22.3% | Reduced |
| Pictet Asset Management Holding SA | 390,884 | $9.84M | 0.01% | +27,434+7.5% | Added |
| Rhenman & Partners Asset Management AB | 374,450 | $9.41M | 0.88% | +142,200+61.2% | Added |
| Schroder Investment Management Group | 329,134 | $8.31M | 0.01% | +156,047+90.2% | Added |
| 683 Capital Management, LLC | 330,000 | $8.29M | 0.69% | +42,000+14.6% | Added |
| Granite Investment Partners, LLC | 327,094 | $8.22M | 0.49% | +327,094 | New |
| J. Goldman & Co LP | 285,992 | $7.18M | 0.28% | +2,839+1.0% | Added |
| Bank of New York Mellon Corp | 271,925 | $6.83M | 0.00% | +23,731+9.6% | Added |
| Natixis | 257,268 | $6.46M | 0.03% | +205,029+392.5% | Added |
| Caption Management, LLC | 254,563 | $6.39M | 0.28% | −50,437−16.5% | Reduced |
| Sphera Funds Management Ltd. | 250,961 | $6.30M | 1.32% | +187,301+294.2% | Added |
| Janus Henderson Group PLC | 230,320 | $5.79M | 0.00% | +195,908+569.3% | Added |
| Invesco Ltd. | 225,976 | $5.68M | 0.00% | +42,960+23.5% | Added |
| Canada Pension Plan Investment Board | 222,200 | $5.58M | 0.00% | +5,200+2.4% | Added |
| Tudor Investment Corp Et Al | 215,000 | $5.40M | 0.03% | +215,000 | New |
| Acadian Asset Management LLC | 205,986 | $5.17M | 0.01% | +193,533+1,554.1% | Added |
| Integral Health Asset Management, LLC | 200,000 | $5.02M | 0.25% | −50,000−20.0% | Reduced |
| Trexquant Investment LP | 194,592 | $4.89M | 0.04% | −392,347−66.8% | Reduced |
| Jump Financial, LLC | 193,876 | $4.87M | 0.06% | −83,772−30.2% | Reduced |
| HRT Financial LP | 192,488 | $4.83M | 0.02% | −161,161−45.6% | Reduced |
| Squarepoint Ops LLC | 192,156 | $4.83M | 0.01% | +139,322+263.7% | Added |
| Apis Capital Advisors, LLC | 192,000 | $4.82M | 0.84% | +192,000 | New |
| Silvercrest Asset Management Group LLC | 190,759 | $4.79M | 0.03% | +233+0.1% | Added |
| Goldman Sachs Group Inc | 189,205 | $4.75M | 0.00% | +64,832+52.1% | Added |
| Barclays PLC | 187,712 | $4.72M | 0.00% | −81,815−30.4% | Reduced |
| California Public Employees Retirement System | 186,328 | $4.68M | 0.00% | +40,140+27.5% | Added |
| Dimensional Fund Advisors LP | 180,925 | $4.54M | 0.00% | +162,235+868.0% | Added |
| Fiduciary Trust Co | 180,254 | $4.53M | 0.05% | −17,925−9.0% | Reduced |
| UBS Asset Management Americas Inc | 178,888 | $4.49M | 0.00% | +11,424+6.8% | Added |
| Bank of Montreal | 176,571 | $4.44M | 0.00% | +16,265+10.1% | Added |
| Rafferty Asset Management, LLC | 171,456 | $4.31M | 0.01% | +3,104+1.8% | Added |
| ExodusPoint Capital Management, LP | 171,156 | $4.30M | 0.05% | −23,602−12.1% | Reduced |
| Gotham Asset Management, LLC | 168,455 | $4.23M | 0.02% | +41,297+32.5% | Added |
| JPMorgan Chase & Co | 157,754 | $3.96M | 0.00% | +104,238+194.8% | Added |
| HighVista Strategies LLC | 150,776 | $3.79M | 0.98% | +5,047+3.5% | Added |
| Rock Springs Capital Management LP | 150,500 | $3.78M | 0.19% | +58,500+63.6% | Added |
| Swiss National Bank | 149,500 | $3.76M | 0.00% | +3,300+2.3% | Added |
| Man Group plc | 144,271 | $3.62M | 0.01% | +77,069+114.7% | Added |
| Bridgewater Associates, LP | 143,805 | $3.61M | 0.01% | +143,805 | New |
| DekaBank Deutsche Girozentrale | 55,000 | $3.50M | 0.01% | 00.0% | Unchanged |
| ING Groep NV | 139,000 | $3.49M | 0.02% | −1,035,500−88.2% | Reduced |
| Exome Asset Management LLC | 135,849 | $3.41M | 1.69% | +135,849 | New |
| Rhumbline Advisers | 116,917 | $2.94M | 0.00% | −512−0.4% | Reduced |
| Two Sigma Advisers, LP | 110,900 | $2.79M | 0.01% | +110,900 | New |
| Algert Global LLC | 109,733 | $2.76M | 0.04% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 104,018 | $2.61M | 0.00% | +55,181+113.0% | Added |
| Wells Fargo & Company | 103,815 | $2.61M | 0.00% | +101,352+4,115.0% | Added |
| Alps Advisors Inc | 103,696 | $2.60M | 0.02% | +40,881+65.1% | Added |
| Edgestream Partners, L.P. | 97,443 | $2.45M | 0.07% | −32,308−24.9% | Reduced |
| Mackenzie Financial Corp | 96,211 | $2.42M | 0.00% | +19,500+25.4% | Added |
| State Board of Administration of Florida Retirement System | 96,125 | $2.41M | 0.00% | +530+0.6% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 95,755 | $2.41M | 0.00% | +49,642+107.7% | Added |
| Price T Rowe Associates Inc | 95,035 | $2.39M | 0.00% | −2,905−3.0% | Reduced |
| Royal Bank of Canada | 88,687 | $2.23M | 0.00% | −57,520−39.3% | Reduced |
| Winton Group Ltd | 86,653 | $2.18M | 0.08% | +86,653 | New |
| Legal & General Group Plc | 85,489 | $2.15M | 0.00% | −6,903−7.5% | Reduced |
| Steward Partners Investment Advisory, LLC | 81,698 | $2.05M | 0.01% | −32,390−28.4% | Reduced |
| Coppell Advisory Solutions LLC | 77,390 | $1.95M | 0.20% | +77,390 | New |