Apellis Pharmaceuticals, Inc.
APLSDelisted May 14, 2026- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001492422
Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.
13F holders, Q4 2025
Institutional positions in Apellis Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 280
- +14 vs. Q3 2025
- Shares held
- 126.4M
- +4.65M (+3.8%) vs. Q3 2025
- Total value
- $3.17B
- +$415.1M (+15.0%) vs. Q3 2025
- New holders
- 61
- 89 more added
- Sold out
- 47
- 102 more reduced
7 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1 | $10.2K |
| Q1 2026 | 324 | $5.56B |
| Q4 2025 | 280 | $3.17B |
| Q3 2025 | 273 | $2.77B |
| Q2 2025 | 247 | $2.28B |
| Q1 2025 | 255 | $2.80B |
| Q4 2024 | 260 | $4.04B |
| Q3 2024 | 265 | $3.41B |
| Q2 2024 | 263 | $4.43B |
| Q1 2024 | 302 | $6.65B |
| Q4 2023 | 284 | $6.82B |
| Q3 2023 | 256 | $4.34B |
| Q2 2023 | 317 | $9.71B |
| Q1 2023 | 282 | $7.28B |
| Q4 2022 | 244 | $5.20B |
| Q3 2022 | 250 | $6.66B |
| Q2 2022 | 212 | $4.15B |
| Q1 2022 | 212 | $4.62B |
| Q4 2021 | 187 | $3.83B |
| Q3 2021 | 181 | $2.29B |
| Q2 2021 | 205 | $4.08B |
| Q1 2021 | 175 | $2.80B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| California State Teachers Retirement System | 73,203 | $1.84M | 0.00% | −95−0.1% | Reduced |
| Ikarian Capital, LLC | 71,747 | $1.80M | 0.23% | −380,155−84.1% | Reduced |
| Raymond James Financial Inc | 66,997 | $1.68M | 0.00% | −10,681−13.8% | Reduced |
| State of Wisconsin Investment Board | 66,916 | $1.68M | 0.00% | −18,845−22.0% | Reduced |
| Balyasny Asset Management LLC | 65,133 | $1.64M | 0.00% | +65,133 | New |
| Profund Advisors LLC | 61,832 | $1.55M | 0.05% | +27,120+78.1% | Added |
| SEI Investments Co | 60,291 | $1.51M | 0.00% | −94,831−61.1% | Reduced |
| PDT Partners, LLC | 53,951 | $1.36M | 0.09% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 53,526 | $1.34M | 0.00% | −526−1.0% | Reduced |
| Hennion & Walsh Asset Management, Inc. | 51,933 | $1.30M | 0.05% | +3,804+7.9% | Added |
| Jane Street Group, LLC | 50,114 | $1.26M | 0.00% | −243,085−82.9% | Reduced |
| Elmind Capital, LP | 50,000 | $1.26M | 0.37% | +50,000 | New |
| Ishara Investments LP | 50,000 | $1.26M | 1.46% | +50,000 | New |
| Police & Firemen's Retirement System of New Jersey | 46,009 | $1.16M | 0.01% | −2,361−4.9% | Reduced |
| Treasurer of the State of North Carolina | 45,170 | $1.14M | 0.00% | −3,296−6.8% | Reduced |
| Voya Investment Management LLC | 43,661 | $1.10M | 0.00% | −129,273−74.8% | Reduced |
| Panagora Asset Management Inc | 42,134 | $1.06M | 0.00% | +42,134 | New |
| CWM, LLC | 41,880 | $1.05M | 0.00% | −52,353−55.6% | Reduced |
| Prelude Capital Management, LLC | 38,521 | $967.6K | 0.07% | +38,521 | New |
| Stifel Financial Corp | 36,661 | $920.9K | 0.00% | +36,661 | New |
| Guggenheim Capital LLC | 36,647 | $920.6K | 0.01% | +2,813+8.3% | Added |
| Handelsbanken Fonder AB | 35,400 | $889.0K | 0.00% | −3,700−9.5% | Reduced |
| Alliancebernstein L.P. | 34,530 | $867.4K | 0.00% | −46,075−57.2% | Reduced |
| Vontobel Holding Ltd. | 34,039 | $855.1K | 0.00% | +34,039 | New |
| Public Employees Retirement System of Ohio | 32,448 | $815.1K | 0.00% | −1,231−3.7% | Reduced |
| FMR LLC | 32,163 | $807.9K | 0.00% | +13,660+73.8% | Added |
| Quantinno Capital Management LP | 31,763 | $797.9K | 0.00% | −16,656−34.4% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 31,581 | $793.3K | 0.02% | −132,232−80.7% | Reduced |
| Dark Forest Capital Management LP | 31,091 | $781.0K | 0.04% | +31,091 | New |
| Amundi | 30,721 | $771.7K | 0.00% | −1,462,957−97.9% | Reduced |
| Wealth Enhancement Advisory Services, LLC | 30,175 | $722.4K | 0.00% | −47,333−61.1% | Reduced |
| Simplex Trading, LLC | 27,187 | $682.9K | 0.02% | −26,714−49.6% | Reduced |
| Virtus Investment Advisers, Inc. | 27,086 | $680.4K | 0.18% | +4,013+17.4% | Added |
| State of New Jersey Common Pension Fund D | 25,863 | $649.7K | 0.00% | +25,863 | New |
| Ieq Capital, LLC | 25,500 | $640.6K | 0.00% | −271,284−91.4% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 25,364 | $637.1K | 0.00% | +4,047+19.0% | Added |
| Erste Asset Management GmbH | 25,300 | $636.8K | 0.01% | 00.0% | Unchanged |
| Virginia Retirement Systems Et Al | 24,365 | $612.0K | 0.00% | −1,100−4.3% | Reduced |
| Quadrature Capital Ltd | 24,075 | $604.8K | 0.01% | +24,075 | New |
| Cerity Partners LLC | 23,971 | $602.2K | 0.00% | −104,139−81.3% | Reduced |
| Entropy Technologies, LP | 23,128 | $581.0K | 0.03% | −1,475−6.0% | Reduced |
| Marex Group plc | 23,000 | $577.8K | 0.01% | +23,000 | New |
| Manufacturers Life Insurance Company, The | 22,852 | $574.0K | 0.00% | +143+0.6% | Added |
| PSP Research LLC | 21,866 | $549.3K | 0.48% | +21,866 | New |
| Boothbay Fund Management, LLC | 21,415 | $537.9K | 0.01% | −157,811−88.1% | Reduced |
| IMC-Chicago, LLC | 21,324 | $535.7K | 0.01% | +21,324 | New |
| Arizona State Retirement System | 21,010 | $527.8K | 0.00% | −1,288−5.8% | Reduced |
| China Universal Asset Management Co., Ltd. | 20,617 | $517.9K | 0.04% | −1,520−6.9% | Reduced |
| ADAR1 Capital Management, LLC | 20,000 | $502.4K | 0.04% | 00.0% | Unchanged |
| Odyssean, LLC | 19,207 | $482.5K | 0.35% | +19,207 | New |
| Diversified Trust Co | 18,942 | $475.8K | 0.01% | +18,942 | New |
| Qube Research & Technologies Ltd | 18,843 | $473.3K | 0.00% | −101,160−84.3% | Reduced |
| Xponance, Inc. | 18,164 | $456.3K | 0.00% | +681+3.9% | Added |
| Advent Capital Management | 18,000 | $452.2K | 0.01% | +18,000 | New |
| Mercer Global Advisors Inc | 17,668 | $443.8K | 0.00% | −21,375−54.7% | Reduced |
| Allianz Asset Management GmbH | 17,000 | $427.0K | 0.00% | 00.0% | Unchanged |
| Jain Global LLC | 16,877 | $423.9K | 0.00% | +16,877 | New |
| Creative Planning | 16,439 | $412.9K | 0.00% | −19,206−53.9% | Reduced |
| KLP Kapitalforvaltning AS | 16,200 | $406.9K | 0.00% | +600+3.8% | Added |
| Brevan Howard Capital Management LP | 16,117 | $404.9K | 0.01% | −74,904−82.3% | Reduced |
| Duncan Williams Asset Management, LLC | 17,005 | $393.7K | 0.10% | 00.0% | Unchanged |
| Vident Advisory, LLC | 15,553 | $390.7K | 0.00% | −19,828−56.0% | Reduced |
| Victory Capital Management Inc | 15,197 | $381.7K | 0.00% | −75−0.5% | Reduced |
| Maven Securities LTD | 15,000 | $376.8K | 0.05% | +15,000 | New |
| GWM Advisors LLC | 14,570 | $366.0K | 0.00% | +14,570 | New |
| M&T Bank Corp | 14,477 | $363.8K | 0.00% | +1,452+11.1% | Added |
| Nomura Holdings Inc | 14,200 | $356.7K | 0.00% | −22,400−61.2% | Reduced |
| Birchview Capital, LP | 14,000 | $351.7K | 0.21% | 00.0% | Unchanged |
| Pallas Capital Advisors LLC | 13,885 | $348.8K | 0.01% | −19,192−58.0% | Reduced |
| Summit Trail Advisors, LLC | 13,851 | $347.9K | 0.01% | +3,575+34.8% | Added |
| Empowered Funds, LLC | 13,381 | $336.1K | 0.01% | +40+0.3% | Added |
| Twinbeech Capital LP | 13,152 | $330.4K | 0.02% | +4,225+47.3% | Added |
| Walleye Trading LLC | 12,699 | $319.0K | 0.01% | +2,258+21.6% | Added |
| Freestone Grove Partners LP | 12,537 | $314.9K | 0.00% | +12,537 | New |
| Wedmont Private Capital | 11,883 | $314.8K | 0.01% | +468+4.1% | Added |
| Quest Partners LLC | 11,741 | $294.9K | 0.02% | −11,358−49.2% | Reduced |
| Bridgefront Capital, LLC | 11,326 | $284.5K | 0.07% | +11,326 | New |
| Franklin Resources Inc | 11,304 | $284.0K | 0.00% | +11,304 | New |
| Teacher Retirement System of Texas | 11,225 | $282.0K | 0.00% | −7,287−39.4% | Reduced |
| Swiss Life Asset Management Ltd | 10,832 | $272.1K | 0.00% | +10,832 | New |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 10,806 | $271.4K | 0.04% | +10,806 | New |
| Perbak Capital Partners LLP | 10,217 | $256.7K | 0.08% | +10,217 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 10,044 | $253.5K | 0.00% | +1,435+16.7% | Added |
| Russell Investments Group, Ltd. | 9,998 | $251.2K | 0.00% | +97+1.0% | Added |
| Graham Capital Management, L.P. | 9,302 | $233.7K | 0.01% | −13,894−59.9% | Reduced |
| Dynasty Wealth Management, LLC | 9,227 | $231.8K | 0.00% | +9,227 | New |
| Mirabella Financial Services LLP | 9,078 | $228.0K | 0.02% | +9,078 | New |
| Vise Technologies, Inc. | 9,012 | $226.4K | 0.00% | +9,012 | New |
| Amalgamated Bank | 8,736 | $219.0K | 0.00% | +62+0.7% | Added |
| Jefferies Financial Group Inc. | 8,718 | $219.0K | 0.00% | −242,837−96.5% | Reduced |
| Quantitative Investment Management, LLC | 8,611 | $216.0K | 0.02% | +8,611 | New |
| Great West Life Assurance Co | 8,495 | $214.0K | 0.00% | −9,252−52.1% | Reduced |
| Laurel Oak Wealth Management, LLC | 8,465 | $212.6K | 0.04% | +8,465 | New |
| Public Employees Retirement Association of Colorado | 8,362 | $210.0K | 0.00% | 00.0% | Unchanged |
| AlphaGrep UK Ltd | 8,323 | $209.1K | 0.07% | +8,323 | New |
| MetLife Investment Management | 6,962 | $174.9K | 0.00% | +60+0.9% | Added |
| Mirae Asset Global Investments Co., Ltd. | 6,148 | $154.4K | 0.00% | +1,266+25.9% | Added |
| Quantbot Technologies LP | 5,608 | $140.9K | 0.00% | +2,795+99.4% | Added |
| Stelac Advisory Services LLC | 5,520 | $138.7K | 0.05% | 00.0% | Unchanged |
| Essential Partners LLC | 5,107 | $128.3K | 0.04% | −12,652−71.2% | Reduced |