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Apellis Pharmaceuticals, Inc.

APLSDelisted
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted in 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q4 2021

Institutional positions in Apellis Pharmaceuticals, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
187
+8 vs. Q3 2021
Shares held
81.0M
+11.5M (+16.6%) vs. Q3 2021
Total value
$3.83B
+$1.54B (+67.1%) vs. Q3 2021
New holders
44
73 more added
Sold out
36
53 more reduced

2 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 187 institutions
Q1 2021: 175 institutionsQ2 2021: 205 institutionsQ3 2021: 181 institutionsQ4 2021: 187 institutionsQ1 2022: 212 institutionsQ2 2022: 212 institutionsQ3 2022: 250 institutionsQ4 2022: 244 institutionsQ1 2023: 282 institutionsQ2 2023: 317 institutionsQ3 2023: 256 institutionsQ4 2023: 284 institutionsQ1 2024: 302 institutionsQ2 2024: 263 institutionsQ3 2024: 265 institutionsQ4 2024: 260 institutionsQ1 2025: 255 institutionsQ2 2025: 247 institutionsQ3 2025: 273 institutionsQ4 2025: 280 institutionsQ1 2026: 324 institutionsQ2 2026: 1 institution
Value heldQ4 2021: $3.91B
Q1 2021: $2.80BQ2 2021: $4.13BQ3 2021: $2.29BQ4 2021: $3.91BQ1 2022: $4.62BQ2 2022: $4.15BQ3 2022: $6.67BQ4 2022: $5.26BQ1 2023: $7.49BQ2 2023: $9.81BQ3 2023: $4.34BQ4 2023: $7.16BQ1 2024: $6.97BQ2 2024: $4.56BQ3 2024: $3.52BQ4 2024: $4.05BQ1 2025: $2.80BQ2 2025: $2.29BQ3 2025: $2.77BQ4 2025: $3.17BQ1 2026: $5.56BQ2 2026: $10.2K
Institutions holding APLS and their total value by quarter
QuarterHoldersValue
Q2 20261$10.2K
Q1 2026324$5.56B
Q4 2025280$3.17B
Q3 2025273$2.77B
Q2 2025247$2.29B
Q1 2025255$2.80B
Q4 2024260$4.05B
Q3 2024265$3.52B
Q2 2024263$4.56B
Q1 2024302$6.97B
Q4 2023284$7.16B
Q3 2023256$4.34B
Q2 2023317$9.81B
Q1 2023282$7.49B
Q4 2022244$5.26B
Q3 2022250$6.67B
Q2 2022212$4.15B
Q1 2022212$4.62B
Q4 2021187$3.91B
Q3 2021181$2.29B
Q2 2021205$4.13B
Q1 2021175$2.80B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q3 2021.

Institutions holding APLS in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Wellington Management Group LLP12,330,653$583.0M0.09%+1,159,081+10.4%Added
Avoro Capital Advisors LLC8,555,555$404.5M6.89%+3,555,555+71.1%Added
Vanguard Group Inc7,917,099$374.3M0.01%+1,164,814+17.3%Added
BlackRock Inc.5,865,712$277.3M0.01%+399,521+7.3%Added
Price T Rowe Associates Inc5,298,491$250.5M0.02%+491,414+10.2%Added
EcoR1 Capital, LLC4,033,882$190.7M6.09%+4,033,882New
State Street Corp2,719,368$128.6M0.01%−106,827−3.8%Reduced
Octagon Capital Advisors LP2,020,911$95.5M18.59%+425,000+26.6%Added
RTW Investments, LP1,990,404$94.1M1.37%+1,990,404New
Jennison Associates LLC1,862,157$88.0M0.06%−216,688−10.4%Reduced
FMR LLC1,614,859$76.4M0.01%00.0%Unchanged
JPMorgan Chase & Co1,587,878$75.1M0.01%+54,736+3.6%Added
Victory Capital Management Inc1,565,977$74.0M0.07%−204,830−11.6%Reduced
Perceptive Advisors LLC1,451,700$68.6M1.06%+836,700+136.0%Added
Geode Capital Management, LLC1,352,829$64.0M0.01%+164,437+13.8%Added
Macquarie Group Ltd1,291,783$61.1M0.05%+171,693+15.3%Added
Logos Global Management LP1,000,000$47.3M4.88%−450,000−31.0%Reduced
Citadel Advisors LLC953,731$45.1M0.05%−904,701−48.7%Reduced
Northern Trust Corp743,867$35.2M0.01%+81,181+12.3%Added
Candriam Luxembourg S.C.A.694,425$32.8M0.21%+439,395+172.3%Added
Bellevue Group AG650,591$30.8M0.32%+602,591+1,255.4%Added
Pictet Asset Management SA646,359$30.6M0.03%+646,359New
Norges Bank640,167$30.3M0.01%+129,989+25.5%Added
Cormorant Asset Management, LP625,000$29.6M1.76%−300,000−32.4%Reduced
Charles Schwab Investment Management Inc591,914$28.0M0.01%+73,103+14.1%Added
Fiduciary Trust Co564,841$26.7M0.44%−350.0%Reduced
Acuta Capital Partners, LLC535,000$25.3M10.63%+459,500+608.6%Added
Goldman Sachs Group Inc498,082$23.5M0.01%−525,088−51.3%Reduced
Rhenman & Partners Asset Management AB430,000$20.6M1.37%−131,269−23.4%Reduced
Lombard Odier Asset Management (Switzerland) SA423,676$20.0M1.28%+216,930+104.9%Added
UBS Asset Management Americas Inc373,674$17.7M0.01%+169,684+83.2%Added
Deerfield Management Company, L.P. (Series C)343,213$16.2M0.34%+343,213New
Deutsche Bank AG338,753$16.0M0.01%+47,744+16.4%Added
Ghost Tree Capital, LLC325,000$15.4M5.88%+125,000+62.5%Added
Tri Locum Partners LP318,269$15.0M6.03%+318,269New
Millennium Management LLC312,002$14.8M0.02%−93,380−23.0%Reduced
Jacobs Levy Equity Management, Inc310,594$14.7M0.10%−203,047−39.5%Reduced
Bank of New York Mellon Corp298,193$14.1M0.00%+28,709+10.7%Added
Bank of America Corp274,906$13.0M0.00%−5,066−1.8%Reduced
Driehaus Capital Management LLC262,897$12.4M0.13%−12,655−4.6%Reduced
Nuveen Asset Management, LLC256,441$10.8M0.00%−9,803−3.7%Reduced
Pier Capital, LLC221,901$10.5M1.11%+65,870+42.2%Added
Caption Management, LLC220,000$10.4M0.65%+198,557+926.0%Added
Tekla Capital Management LLC195,820$9.26M0.30%00.0%Unchanged
Bank of Montreal179,681$8.77M0.00%−73,847−29.1%Reduced
Prudential Financial Inc180,270$8.74M0.01%+8,875+5.2%Added
SG Americas Securities, LLC177,734$8.40M0.06%−6,280−3.4%Reduced
Swiss National Bank168,900$7.99M0.00%+35,500+26.6%Added
Banque Pictet & Cie SA168,489$7.97M0.06%+151,606+898.0%Added
Ameriprise Financial Inc166,688$7.88M0.00%−36,024−17.8%Reduced
TD Asset Management Inc161,045$7.61M0.01%+41,381+34.6%Added
Barclays PLC145,248$6.87M0.00%+112,555+344.3%Added
Asymmetry Capital Management, L.P.139,445$6.59M3.50%+139,445New
Teachers Retirement System of the State of Kentucky138,931$6.57M0.06%+7,741+5.9%Added
Hennion & Walsh Asset Management, Inc.136,760$6.47M0.32%−45,445−24.9%Reduced
Clough Capital Partners L P131,749$6.23M0.42%−6,000−4.4%Reduced
Privium Fund Management B.V.127,616$6.12M1.22%+127,616New
Balyasny Asset Management LLC128,514$6.08M0.03%−54,633−29.8%Reduced
Rafferty Asset Management, LLC125,910$5.95M0.03%+36,711+41.2%Added
Frontier Capital Management Co LLC123,490$5.84M0.05%−152,420−55.2%Reduced
Integral Health Asset Management, LLC120,000$5.67M1.58%−70,000−36.8%Reduced
Citigroup Inc119,688$5.66M0.01%+49,396+70.3%Added
Schonfeld Strategic Advisors LLC118,558$5.61M0.05%+107,258+949.2%Added
Walleye Capital LLC115,133$5.44M0.18%+115,133New
UBS Group AG109,387$5.17M0.00%−87,495−44.4%Reduced
Russell Investments Group, Ltd.107,951$5.10M0.01%−16,483−13.2%Reduced
Royal Bank of Canada105,190$4.97M0.00%+13,309+14.5%Added
Voya Investment Management LLC103,876$4.91M0.01%+78,732+313.1%Added
California State Teachers Retirement System103,701$4.90M0.01%+19,084+22.6%Added
Lisanti Capital Growth, LLC103,425$4.89M0.71%+103,425New
Jane Street Group, LLC100,711$4.76M0.01%+84,768+531.7%Added
Neuberger Berman Group LLC101,123$4.68M0.00%+36,927+57.5%Added
State of Wisconsin Investment Board95,700$4.53M0.01%+5,700+6.3%Added
Polar Asset Management Partners Inc.86,600$4.09M0.05%+58,600+209.3%Added
Ensign Peak Advisors, Inc85,589$4.05M0.01%+82,647+2,809.2%Added
Verition Fund Management LLC84,493$4.00M0.05%+84,493New
Granahan Investment Management Inc83,601$3.95M0.08%+83,601New
Alliancebernstein L.P.80,000$3.78M0.00%+800+1.0%Added
Voloridge Investment Management, LLC76,162$3.60M0.02%−272,546−78.2%Reduced
Rhumbline Advisers73,929$3.50M0.00%+4,534+6.5%Added
Private Advisor Group, LLC73,242$3.46M0.03%−72,626−49.8%Reduced
Legal & General Group Plc69,167$3.27M0.00%+11,268+19.5%Added
Susquehanna International Group, LLP68,749$3.25M0.00%−40,661−37.2%Reduced
Morgan Stanley67,659$3.20M0.00%−109,637−61.8%Reduced
Assenagon Asset Management S.A.67,282$3.18M0.01%+67,282New
New York State Common Retirement Fund65,814$3.11M0.00%+18,810+40.0%Added
State of New Jersey Common Pension Fund D63,934$3.02M0.01%+20,250+46.4%Added
Wells Fargo & Company63,925$3.02M0.00%+13,336+26.4%Added
Credit Suisse AG63,032$2.98M0.00%+3,845+6.5%Added
EFG Asset Management (North America) Corp.57,055$2.70M0.35%+57,055New
Castleark Management LLC53,130$2.51M0.09%+53,130New
Baird Financial Group, Inc.53,075$2.51M0.01%+22,377+72.9%Added
Invesco Ltd.48,549$2.29M0.00%−6,189−11.3%Reduced
Guggenheim Capital LLC48,251$2.28M0.01%+4,607+10.6%Added
J. Goldman & Co LP48,013$2.27M0.21%+48,013New
Aufman Associates Inc46,751$2.21M1.63%−6,891−12.8%Reduced
Parametric Portfolio Associates LLC43,733$2.07M0.00%−6,157−12.3%Reduced
DekaBank Deutsche Girozentrale43,400$2.04M0.00%+18,700+75.7%Added
Woodline Partners LP41,199$1.95M0.03%−66,877−61.9%Reduced
Toronto Dominion Bank38,421$1.82M0.00%+38,421New