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Apellis Pharmaceuticals, Inc.

APLSDelisted
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted in 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q2 2023

Institutional positions in Apellis Pharmaceuticals, Inc. as of Jun 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
317
+37 vs. Q1 2023
Shares held
106.6M
−3.79M (−3.4%) vs. Q1 2023
Total value
$9.71B
+$2.43B (+33.4%) vs. Q1 2023
New holders
69
100 more added
Sold out
32
120 more reduced

2 institutions that held it in Q1 2023 haven't filed for Q2 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2023: 317 institutions
Q1 2021: 175 institutionsQ2 2021: 205 institutionsQ3 2021: 181 institutionsQ4 2021: 187 institutionsQ1 2022: 212 institutionsQ2 2022: 212 institutionsQ3 2022: 250 institutionsQ4 2022: 244 institutionsQ1 2023: 282 institutionsQ2 2023: 317 institutionsQ3 2023: 256 institutionsQ4 2023: 284 institutionsQ1 2024: 302 institutionsQ2 2024: 263 institutionsQ3 2024: 265 institutionsQ4 2024: 260 institutionsQ1 2025: 255 institutionsQ2 2025: 247 institutionsQ3 2025: 273 institutionsQ4 2025: 280 institutionsQ1 2026: 324 institutionsQ2 2026: 1 institution
Value heldQ2 2023: $9.81B
Q1 2021: $2.80BQ2 2021: $4.13BQ3 2021: $2.29BQ4 2021: $3.91BQ1 2022: $4.62BQ2 2022: $4.15BQ3 2022: $6.67BQ4 2022: $5.26BQ1 2023: $7.49BQ2 2023: $9.81BQ3 2023: $4.34BQ4 2023: $7.16BQ1 2024: $6.97BQ2 2024: $4.56BQ3 2024: $3.52BQ4 2024: $4.05BQ1 2025: $2.80BQ2 2025: $2.29BQ3 2025: $2.77BQ4 2025: $3.17BQ1 2026: $5.56BQ2 2026: $10.2K
Institutions holding APLS and their total value by quarter
QuarterHoldersValue
Q2 20261$10.2K
Q1 2026324$5.56B
Q4 2025280$3.17B
Q3 2025273$2.77B
Q2 2025247$2.29B
Q1 2025255$2.80B
Q4 2024260$4.05B
Q3 2024265$3.52B
Q2 2024263$4.56B
Q1 2024302$6.97B
Q4 2023284$7.16B
Q3 2023256$4.34B
Q2 2023317$9.81B
Q1 2023282$7.49B
Q4 2022244$5.26B
Q3 2022250$6.67B
Q2 2022212$4.15B
Q1 2022212$4.62B
Q4 2021187$3.91B
Q3 2021181$2.29B
Q2 2021205$4.13B
Q1 2021175$2.80B

Institutions, Q2 2023

Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q1 2023.

Institutions holding APLS in Q2 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Avoro Capital Advisors LLC11,111,111$1.01B13.73%00.0%Unchanged
Vanguard Group Inc9,401,290$856.5M0.02%−127,654−1.3%Reduced
Price T Rowe Associates Inc7,072,226$644.3M0.09%+2,482,186+54.1%Added
Wellington Management Group LLP6,664,275$607.1M0.12%−1,614,164−19.5%Reduced
BlackRock Inc.5,747,627$523.6M0.01%−1,907,824−24.9%Reduced
T. Rowe Price Investment Management, Inc.5,638,875$513.7M0.35%−121,789−2.1%Reduced
EcoR1 Capital, LLC5,451,647$496.6M13.09%00.0%Unchanged
FMR LLC4,225,595$385.0M0.03%+2,100,158+98.8%Added
Octagon Capital Advisors LP2,618,300$238.5M33.28%−631,700−19.4%Reduced
State Street Corp2,283,085$208.0M0.01%−696,777−23.4%Reduced
Jennison Associates LLC1,970,603$179.5M0.15%−642,164−24.6%Reduced
JPMorgan Chase & Co1,786,982$162.8M0.02%+138,530+8.4%Added
Janus Henderson Group PLC1,776,905$161.9M0.10%−2,904,577−62.0%Reduced
Boxer Capital, LLC1,576,000$143.6M6.66%00.0%Unchanged
Geode Capital Management, LLC1,498,389$136.5M0.02%−339,890−18.5%Reduced
Cormorant Asset Management, LP1,310,000$119.3M6.80%−50,000−3.7%Reduced
Point72 Asset Management, L.P.1,239,361$112.9M0.39%−640,363−34.1%Reduced
Invesco Ltd.1,152,396$105.0M0.03%+111,415+10.7%Added
Lord, Abbett & Co. LLC1,068,143$97.3M0.33%+163,915+18.1%Added
Artal Group S.A.1,050,067$95.7M3.06%−166,245−13.7%Reduced
Norges Bank1,023,026$93.2M0.02%+91,516+9.8%Added
Pictet Asset Management SA928,624$84.6M0.10%+478,585+106.3%Added
Millennium Management LLC918,811$83.7M0.09%+370,610+67.6%Added
OrbiMed Advisors LLC910,200$82.9M1.51%00.0%Unchanged
Northern Trust Corp852,272$77.6M0.01%−16,916−1.9%Reduced
Charles Schwab Investment Management Inc828,522$75.5M0.02%−154,987−15.8%Reduced
Perceptive Advisors LLC812,037$74.0M2.15%+256,693+46.2%Added
Macquarie Group Ltd775,480$70.6M0.08%−635,999−45.1%Reduced
Morgan Stanley756,665$68.9M0.01%+3,803+0.5%Added
1832 Asset Management L.P.661,700$60.3M0.12%+530,800+405.5%Added
Goldman Sachs Group Inc634,897$57.8M0.01%−28,298−4.3%Reduced
Logos Global Management LP625,000$56.9M7.86%−175,000−21.9%Reduced
Westfield Capital Management Co LP596,232$54.3M0.35%−196,014−24.7%Reduced
Citadel Advisors LLC528,572$48.2M0.05%+354,512+203.7%Added
Fiera Capital Corp527,920$48.1M0.14%−12,462−2.3%Reduced
D. E. Shaw & Co., Inc.527,811$48.1M0.07%+114,958+27.8%Added
Laurion Capital Management LP522,929$47.6M2.04%+148,590+39.7%Added
Bellevue Group AG518,495$47.2M0.67%−590,887−53.3%Reduced
Assenagon Asset Management S.A.498,710$45.4M0.18%−244,536−32.9%Reduced
Jane Street Group, LLC481,082$43.8M0.06%+417,698+659.0%Added
TD Asset Management Inc478,726$43.6M0.05%+100,758+26.7%Added
Deutsche Bank AG478,366$43.6M0.02%−121,062−20.2%Reduced
Avidity Partners Management LP468,700$42.7M1.49%+468,700New
Polar Capital Holdings Plc465,000$42.4M0.29%00.0%Unchanged
Eagle Asset Management Inc450,932$41.1M0.23%+221,550+96.6%Added
Nicholas Investment Partners, LP414,419$37.8M2.58%+77,468+23.0%Added
Bank of America Corp409,842$37.3M0.00%−197,893−32.6%Reduced
Victory Capital Management Inc400,957$36.5M0.04%−161,212−28.7%Reduced
Eventide Asset Management, LLC397,141$36.2M0.61%−97,859−19.8%Reduced
Bank of New York Mellon Corp357,289$32.5M0.01%−35,107−8.9%Reduced
Driehaus Capital Management LLC347,376$31.6M0.40%+76,683+28.3%Added
Marshall Wace, LLP342,352$31.2M0.07%+249,906+270.3%Added
Candriam Luxembourg S.C.A.326,507$29.7M0.21%−117,000−26.4%Reduced
Susquehanna International Group, LLP315,910$28.8M0.05%+234,114+286.2%Added
Deerfield Management Company, L.P. (Series C)313,289$28.5M0.61%+313,289New
Barclays PLC312,230$28.4M0.02%+70,049+28.9%Added
HRT Financial LP309,024$28.2M0.26%+309,024New
Balyasny Asset Management LLC304,169$27.7M0.08%−313,728−50.8%Reduced
New York State Common Retirement Fund300,995$27.4M0.04%+57,875+23.8%Added
Acuta Capital Partners, LLC297,596$27.1M18.37%+7,096+2.4%Added
PFM Health Sciences, LP274,498$25.0M1.01%−9,771−3.4%Reduced
Fiduciary Trust Co273,916$25.0M0.44%−268,375−49.5%Reduced
Nuveen Asset Management, LLC262,398$23.9M0.01%−87,156−24.9%Reduced
Finepoint Capital LP241,690$22.0M7.62%−42,000−14.8%Reduced
Voya Investment Management LLC221,414$20.2M0.02%−57,772−20.7%Reduced
Rhenman & Partners Asset Management AB190,000$17.3M1.82%+5,000+2.7%Added
California Public Employees Retirement System182,188$16.6M0.01%+40,182+28.3%Added
Fred Alger Management, LLC181,995$16.6M0.08%−249−0.1%Reduced
Ghost Tree Capital, LLC180,000$16.4M5.92%+15,380+9.3%Added
Prudential Financial Inc177,080$16.1M0.02%−259−0.1%Reduced
Swiss National Bank175,700$16.0M0.01%−15,300−8.0%Reduced
AXA S.A.173,495$15.8M0.05%+2,386+1.4%Added
Tekla Capital Management LLC173,248$15.8M0.62%+38,124+28.2%Added
Manufacturers Life Insurance Company, The169,673$15.5M0.01%+33,077+24.2%Added
Franklin Resources Inc165,710$15.1M0.01%+65,449+65.3%Added
Schonfeld Strategic Advisors LLC164,203$15.0M0.13%+88,176+116.0%Added
Connor, Clark & Lunn Investment Management Ltd.149,976$13.7M0.07%−2,019−1.3%Reduced
Federated Hermes, Inc.147,465$13.4M0.03%−363,837−71.2%Reduced
Sectoral Asset Management Inc143,859$13.1M2.19%−28,631−16.6%Reduced
Voloridge Investment Management, LLC143,402$13.1M0.06%+77,167+116.5%Added
Ameriprise Financial Inc141,078$12.9M0.00%+61,405+77.1%Added
Royal Bank of Canada140,485$12.8M0.00%+3,242+2.4%Added
Renaissance Technologies LLC138,513$12.6M0.02%+138,513New
Russell Investments Group, Ltd.137,527$12.5M0.02%−673−0.5%Reduced
Ikarian Capital, LLC133,800$12.2M4.30%+33,800+33.8%Added
Rhumbline Advisers132,873$12.1M0.01%+1,912+1.5%Added
Dimensional Fund Advisors LP131,787$12.0M0.00%+37,801+40.2%Added
Senator Investment Group LP130,000$11.8M0.53%+130,000New
International Biotechnology Trust PLC129,700$11.8M3.60%+98,000+309.1%Added
Allspring Global Investments Holdings, LLC128,655$11.7M0.02%−2,256−1.7%Reduced
The PNC Financial Services Group, Inc.122,351$11.1M0.01%+60,886+99.1%Added
Ergoteles LLC114,713$10.5M0.50%+114,713New
Granahan Investment Management Inc113,775$10.4M0.32%−49,676−30.4%Reduced
Saturn V Capital Management LLC107,406$9.78M5.43%−15,759−12.8%Reduced
Banque Pictet & Cie SA107,135$9.76M0.09%−31,467−22.7%Reduced
Polar Asset Management Partners Inc.105,810$9.64M0.19%+6,600+6.7%Added
California State Teachers Retirement System104,487$9.52M0.01%−8,116−7.2%Reduced
Artia Global Partners LP102,940$9.38M3.23%+102,940New
SG Americas Securities, LLC101,111$9.21M0.08%+90,048+814.0%Added
Kornitzer Capital Management Inc100,545$9.16M0.18%+100,545New