Apellis Pharmaceuticals, Inc.
APLSDelisted- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001492422
Apellis Pharmaceuticals, Inc. was delisted in 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.
13F holders, Q1 2022
Institutional positions in Apellis Pharmaceuticals, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 212
- +28 vs. Q4 2021
- Shares held
- 91.0M
- +10.1M (+12.5%) vs. Q4 2021
- Total value
- $4.62B
- +$799.1M (+20.9%) vs. Q4 2021
- New holders
- 52
- 73 more added
- Sold out
- 24
- 64 more reduced
3 institutions that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1 | $10.2K |
| Q1 2026 | 324 | $5.56B |
| Q4 2025 | 280 | $3.17B |
| Q3 2025 | 273 | $2.77B |
| Q2 2025 | 247 | $2.29B |
| Q1 2025 | 255 | $2.80B |
| Q4 2024 | 260 | $4.05B |
| Q3 2024 | 265 | $3.52B |
| Q2 2024 | 263 | $4.56B |
| Q1 2024 | 302 | $6.97B |
| Q4 2023 | 284 | $7.16B |
| Q3 2023 | 256 | $4.34B |
| Q2 2023 | 317 | $9.81B |
| Q1 2023 | 282 | $7.49B |
| Q4 2022 | 244 | $5.26B |
| Q3 2022 | 250 | $6.67B |
| Q2 2022 | 212 | $4.15B |
| Q1 2022 | 212 | $4.62B |
| Q4 2021 | 187 | $3.91B |
| Q3 2021 | 181 | $2.29B |
| Q2 2021 | 205 | $4.13B |
| Q1 2021 | 175 | $2.80B |
Institutions, Q1 2022
Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q4 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Wellington Management Group LLP | 14,199,294 | $721.5M | 0.12% | +1,868,641+15.2% | Added |
| Avoro Capital Advisors LLC | 9,450,000 | $480.2M | 8.77% | +894,445+10.5% | Added |
| Vanguard Group Inc | 8,569,170 | $435.4M | 0.01% | +652,071+8.2% | Added |
| Price T Rowe Associates Inc | 7,884,839 | $400.6M | 0.04% | +2,586,348+48.8% | Added |
| BlackRock Inc. | 5,923,920 | $301.0M | 0.01% | +58,208+1.0% | Added |
| EcoR1 Capital, LLC | 5,183,431 | $263.4M | 8.24% | +1,149,549+28.5% | Added |
| State Street Corp | 2,906,456 | $147.7M | 0.01% | +187,088+6.9% | Added |
| Jennison Associates LLC | 2,704,390 | $137.4M | 0.10% | +842,233+45.2% | Added |
| Octagon Capital Advisors LP | 2,340,059 | $118.9M | 25.70% | +319,148+15.8% | Added |
| Geode Capital Management, LLC | 1,493,520 | $75.9M | 0.01% | +140,691+10.4% | Added |
| Perceptive Advisors LLC | 1,481,700 | $75.3M | 1.51% | +30,000+2.1% | Added |
| FMR LLC | 1,397,592 | $71.0M | 0.01% | −217,267−13.5% | Reduced |
| Victory Capital Management Inc | 1,324,964 | $67.2M | 0.07% | −241,013−15.4% | Reduced |
| Macquarie Group Ltd | 1,321,558 | $67.1M | 0.05% | +29,775+2.3% | Added |
| Boxer Capital, LLC | 1,303,700 | $66.2M | 3.40% | +1,303,700 | New |
| JPMorgan Chase & Co | 1,266,238 | $64.3M | 0.01% | −321,640−20.3% | Reduced |
| Cormorant Asset Management, LP | 1,125,000 | $57.2M | 4.39% | +500,000+80.0% | Added |
| Bellevue Group AG | 1,098,712 | $55.8M | 0.65% | +448,121+68.9% | Added |
| Marshall Wace, LLP | 915,163 | $46.5M | 0.10% | +915,163 | New |
| Logos Global Management LP | 900,000 | $45.7M | 5.93% | −100,000−10.0% | Reduced |
| Pictet Asset Management SA | 897,956 | $45.6M | 0.05% | +251,597+38.9% | Added |
| Norges Bank | 814,965 | $41.4M | 0.01% | +174,798+27.3% | Added |
| Northern Trust Corp | 765,202 | $38.9M | 0.01% | +21,335+2.9% | Added |
| Charles Schwab Investment Management Inc | 655,308 | $33.3M | 0.01% | +63,394+10.7% | Added |
| Driehaus Capital Management LLC | 628,645 | $31.9M | 0.39% | +365,748+139.1% | Added |
| Fiduciary Trust Co | 564,826 | $28.7M | 0.51% | −150.0% | Reduced |
| Acuta Capital Partners, LLC | 554,000 | $28.1M | 13.39% | +19,000+3.6% | Added |
| Deutsche Bank AG | 544,311 | $27.7M | 0.01% | +205,558+60.7% | Added |
| Assenagon Asset Management S.A. | 513,027 | $26.1M | 0.08% | +445,745+662.5% | Added |
| Goldman Sachs Group Inc | 500,254 | $25.4M | 0.01% | +2,172+0.4% | Added |
| Candriam Luxembourg S.C.A. | 466,095 | $23.7M | 0.16% | −228,330−32.9% | Reduced |
| Citadel Advisors LLC | 429,252 | $21.8M | 0.03% | −524,479−55.0% | Reduced |
| UBS Asset Management Americas Inc | 390,140 | $19.8M | 0.01% | +16,466+4.4% | Added |
| Bank of America Corp | 381,958 | $19.4M | 0.00% | +107,052+38.9% | Added |
| Rhenman & Partners Asset Management AB | 377,000 | $19.2M | 1.89% | −53,000−12.3% | Reduced |
| Prudential Financial Inc | 332,202 | $16.9M | 0.02% | +151,932+84.3% | Added |
| Adage Capital Partners GP, L.L.C. | 325,000 | $16.5M | 0.03% | +325,000 | New |
| Bank of New York Mellon Corp | 315,480 | $16.0M | 0.00% | +17,287+5.8% | Added |
| Nuveen Asset Management, LLC | 263,645 | $13.7M | 0.00% | +7,204+2.8% | Added |
| Natixis | 268,100 | $13.6M | 0.05% | +268,100 | New |
| Morgan Stanley | 253,389 | $12.9M | 0.00% | +185,730+274.5% | Added |
| Ghost Tree Capital, LLC | 250,000 | $12.7M | 6.29% | −75,000−23.1% | Reduced |
| Caas Capital Management LP | 250,000 | $12.7M | 2.24% | +250,000 | New |
| TD Asset Management Inc | 247,686 | $12.6M | 0.01% | +86,641+53.8% | Added |
| Maven Securities LTD | 221,400 | $11.2M | 2.33% | +221,400 | New |
| Lombard Odier Asset Management (Switzerland) SA | 221,251 | $11.2M | 0.88% | −202,425−47.8% | Reduced |
| Avidity Partners Management LP | 210,000 | $10.7M | 0.24% | +210,000 | New |
| Artal Group S.A. | 200,000 | $10.2M | 0.43% | +200,000 | New |
| Tekla Capital Management LLC | 195,820 | $9.95M | 0.35% | 00.0% | Unchanged |
| Banque Pictet & Cie SA | 189,223 | $9.61M | 0.07% | +20,734+12.3% | Added |
| Swiss National Bank | 181,100 | $9.20M | 0.01% | +12,200+7.2% | Added |
| Alliancebernstein L.P. | 178,670 | $9.08M | 0.00% | +98,670+123.3% | Added |
| Ameriprise Financial Inc | 169,621 | $8.62M | 0.00% | +2,933+1.8% | Added |
| Bank of Montreal | 168,107 | $8.32M | 0.00% | −11,574−6.4% | Reduced |
| Granahan Investment Management Inc | 153,923 | $7.82M | 0.19% | +70,322+84.1% | Added |
| Sessa Capital IM, L.P. | 149,000 | $7.57M | 0.46% | +149,000 | New |
| Teachers Retirement System of the State of Kentucky | 144,468 | $7.34M | 0.07% | +5,537+4.0% | Added |
| Clough Capital Partners L P | 142,409 | $7.24M | 0.55% | +10,660+8.1% | Added |
| Privium Fund Management B.V. | 137,616 | $6.99M | 1.58% | +10,000+7.8% | Added |
| Invesco Ltd. | 133,183 | $6.77M | 0.00% | +84,634+174.3% | Added |
| Pier Capital, LLC | 130,208 | $6.62M | 0.84% | −91,693−41.3% | Reduced |
| Rafferty Asset Management, LLC | 123,495 | $6.28M | 0.04% | −2,415−1.9% | Reduced |
| Hennion & Walsh Asset Management, Inc. | 119,322 | $6.06M | 0.32% | −17,438−12.8% | Reduced |
| UBS Group AG | 114,649 | $5.83M | 0.00% | +5,262+4.8% | Added |
| Nomura Holdings Inc | 104,067 | $5.72M | 0.04% | +90,576+671.4% | Added |
| Silverarc Capital Management, LLC | 105,368 | $5.35M | 2.53% | +105,368 | New |
| California State Teachers Retirement System | 98,930 | $5.03M | 0.01% | −4,771−4.6% | Reduced |
| Manufacturers Life Insurance Company, The | 100,299 | $5.00M | 0.00% | +64,350+179.0% | Added |
| Voya Investment Management LLC | 96,009 | $4.88M | 0.01% | −7,867−7.6% | Reduced |
| State of Wisconsin Investment Board | 95,700 | $4.86M | 0.01% | 00.0% | Unchanged |
| DAFNA Capital Management LLC | 93,935 | $4.77M | 1.24% | +93,935 | New |
| Royal Bank of Canada | 89,782 | $4.56M | 0.00% | −15,408−14.6% | Reduced |
| Rhumbline Advisers | 77,764 | $3.95M | 0.01% | +3,835+5.2% | Added |
| New York State Common Retirement Fund | 77,691 | $3.95M | 0.00% | +11,877+18.0% | Added |
| Susquehanna International Group, LLP | 75,635 | $3.84M | 0.01% | +6,886+10.0% | Added |
| Jane Street Group, LLC | 75,110 | $3.82M | 0.01% | −25,601−25.4% | Reduced |
| Voloridge Investment Management, LLC | 73,426 | $3.73M | 0.02% | −2,736−3.6% | Reduced |
| Private Advisor Group, LLC | 73,340 | $3.73M | 0.03% | +98+0.1% | Added |
| Legal & General Group Plc | 70,357 | $3.58M | 0.00% | +1,190+1.7% | Added |
| Credit Suisse AG | 70,266 | $3.57M | 0.00% | +7,234+11.5% | Added |
| Sectoral Asset Management Inc | 69,500 | $3.53M | 0.63% | +69,500 | New |
| Fred Alger Management, LLC | 68,783 | $3.50M | 0.01% | +68,783 | New |
| Man Group plc | 63,852 | $3.24M | 0.01% | +63,852 | New |
| Nicholas Investment Partners, LP | 62,000 | $3.15M | 0.22% | +62,000 | New |
| Millennium Management LLC | 60,505 | $3.07M | 0.00% | −251,497−80.6% | Reduced |
| State of New Jersey Common Pension Fund D | 59,226 | $3.01M | 0.01% | −4,708−7.4% | Reduced |
| First Trust Advisors LP | 57,809 | $2.94M | 0.00% | +57,809 | New |
| The PNC Financial Services Group, Inc. | 57,699 | $2.93M | 0.00% | +44,751+345.6% | Added |
| EFG Asset Management (North America) Corp. | 56,550 | $2.87M | 0.43% | −505−0.9% | Reduced |
| Group One Trading, L.P. | 55,546 | $2.82M | 0.06% | +19,525+54.2% | Added |
| Baird Financial Group, Inc. | 54,266 | $2.76M | 0.01% | +1,191+2.2% | Added |
| Verition Fund Management LLC | 52,899 | $2.69M | 0.05% | −31,594−37.4% | Reduced |
| Barclays PLC | 52,604 | $2.67M | 0.00% | −92,644−63.8% | Reduced |
| RTW Investments, LP | 51,194 | $2.60M | 0.05% | −1,939,210−97.4% | Reduced |
| Lisanti Capital Growth, LLC | 50,040 | $2.54M | 0.29% | −53,385−51.6% | Reduced |
| Tudor Investment Corp Et Al | 48,840 | $2.48M | 0.06% | +48,840 | New |
| Polar Asset Management Partners Inc. | 48,200 | $2.45M | 0.03% | −38,400−44.3% | Reduced |
| Russell Investments Group, Ltd. | 47,749 | $2.42M | 0.00% | −60,202−55.8% | Reduced |
| Guggenheim Capital LLC | 43,099 | $2.19M | 0.01% | −5,152−10.7% | Reduced |
| Neuberger Berman Group LLC | 41,906 | $2.13M | 0.00% | −59,217−58.6% | Reduced |