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Apellis Pharmaceuticals, Inc.

APLSDelisted May 14, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q1 2022

Institutional positions in Apellis Pharmaceuticals, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
212
+28 vs. Q4 2021
Shares held
91.0M
+10.1M (+12.5%) vs. Q4 2021
Total value
$4.62B
+$799.1M (+20.9%) vs. Q4 2021
New holders
52
73 more added
Sold out
24
64 more reduced

3 institutions that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 212 institutions
Q1 2021: 175 institutionsQ2 2021: 205 institutionsQ3 2021: 181 institutionsQ4 2021: 187 institutionsQ1 2022: 212 institutionsQ2 2022: 212 institutionsQ3 2022: 250 institutionsQ4 2022: 244 institutionsQ1 2023: 282 institutionsQ2 2023: 317 institutionsQ3 2023: 256 institutionsQ4 2023: 284 institutionsQ1 2024: 302 institutionsQ2 2024: 263 institutionsQ3 2024: 265 institutionsQ4 2024: 260 institutionsQ1 2025: 255 institutionsQ2 2025: 247 institutionsQ3 2025: 273 institutionsQ4 2025: 280 institutionsQ1 2026: 324 institutionsQ2 2026: 1 institution
Value heldQ1 2022: $4.62B
Q1 2021: $2.80BQ2 2021: $4.08BQ3 2021: $2.29BQ4 2021: $3.83BQ1 2022: $4.62BQ2 2022: $4.15BQ3 2022: $6.66BQ4 2022: $5.20BQ1 2023: $7.28BQ2 2023: $9.71BQ3 2023: $4.34BQ4 2023: $6.82BQ1 2024: $6.65BQ2 2024: $4.43BQ3 2024: $3.41BQ4 2024: $4.04BQ1 2025: $2.80BQ2 2025: $2.28BQ3 2025: $2.77BQ4 2025: $3.17BQ1 2026: $5.56BQ2 2026: $10.2K
Institutions holding APLS and their total value by quarter
QuarterHoldersValue
Q2 20261$10.2K
Q1 2026324$5.56B
Q4 2025280$3.17B
Q3 2025273$2.77B
Q2 2025247$2.28B
Q1 2025255$2.80B
Q4 2024260$4.04B
Q3 2024265$3.41B
Q2 2024263$4.43B
Q1 2024302$6.65B
Q4 2023284$6.82B
Q3 2023256$4.34B
Q2 2023317$9.71B
Q1 2023282$7.28B
Q4 2022244$5.20B
Q3 2022250$6.66B
Q2 2022212$4.15B
Q1 2022212$4.62B
Q4 2021187$3.83B
Q3 2021181$2.29B
Q2 2021205$4.08B
Q1 2021175$2.80B

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q4 2021.

Institutions holding APLS in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Allworth Financial LP4$00.00%−200−98.0%Reduced
FinTrust Capital Advisors, LLC5$00.00%00.0%Unchanged
Parallax Volatility Advisers, L.P.10$1.00K0.00%−10,926−99.9%Reduced
Massmutual Trust Co FSB19$1.00K0.00%+19New
TCWP LLC31$1.00K0.00%+31New
CWM, LLC68$3.00K0.00%+68New
Captrust Financial Advisors82$4.00K0.00%−244−74.8%Reduced
Rockefeller Capital Management L.P.111$5.00K0.00%−161−59.2%Reduced
Lindbrook Capital, LLC93$5.00K0.00%+55+144.7%Added
Signaturefd, LLC92$5.00K0.00%+92New
Parallel Advisors, LLC130$6.00K0.00%−2−1.5%Reduced
Itau Unibanco Holding S.A.163$8.00K0.00%00.0%Unchanged
Covestor Ltd276$14.0K0.01%+257+1,352.6%Added
Daiwa Securities Group Inc.298$15.0K0.00%00.0%Unchanged
TCI Wealth Advisors, Inc.308$16.0K0.00%00.0%Unchanged
Future Financial Wealth Managment LLC500$25.0K0.02%00.0%Unchanged
Walleye Trading LLC518$26.0K0.00%+518New
Jefferies Group LLC757$38.5K0.00%+757New
US Bancorp1,110$56.0K0.00%+884+391.2%Added
Harbor Investment Advisory, LLC1,113$57.0K0.01%−154−12.2%Reduced
Cowen and Company, LLC1,230$62.0K0.01%+1,230New
CSS LLC1,446$73.0K0.00%+1,446New
Nisa Investment Advisors, LLC1,860$95.0K0.00%−190−9.3%Reduced
Cutler Group LP2,263$114.0K0.01%−3,030−57.2%Reduced
Advisor Group Holdings, Inc.2,605$132.0K0.00%−741−22.1%Reduced
Lazard Asset Management LLC2,683$136.0K0.00%+2,683New
S.A. Mason LLC2,745$139.0K0.09%−1,410−33.9%Reduced
Simplex Trading, LLC2,967$150.0K0.00%+2,967New
Union Investments & Development Ltd.3,000$152.0K0.05%00.0%Unchanged
DuPont Capital Management Corp3,167$161.0K0.01%+3,167New
STRS Ohio3,200$162.0K0.00%+100+3.2%Added
Jacob Asset Management of New York LLC3,299$168.0K0.10%−9,556−74.3%Reduced
Great West Life Assurance Co3,734$202.0K0.00%+500+15.5%Added
IMA Wealth, Inc.4,000$203.0K0.05%00.0%Unchanged
Mackenzie Financial Corp4,047$206.0K0.00%+4,047New
SG Americas Securities, LLC4,145$211.0K0.00%−173,589−97.7%Reduced
Point72 Hong Kong Ltd4,181$212.0K0.02%+3,420+449.4%Added
Amundi3,923$221.0K0.00%00.0%Unchanged
Y-Intercept (Hong Kong) Ltd4,363$222.0K0.05%+4,363New
Metropolitan Life Insurance Co4,894$248.7K0.01%−13,512−73.4%Reduced
Sandia Investment Management LP5,000$254.0K0.04%+5,000New
XTX Topco Ltd5,422$275.0K0.12%+5,422New
LSP Investment Advisors, LLC5,500$279.0K0.08%00.0%Unchanged
Henshaw Capital LLC5,769$293.1K0.02%−750−11.5%Reduced
Creative Planning5,931$301.0K0.00%00.0%Unchanged
Virginia Retirement Systems Et Al6,000$305.0K0.00%+400+7.1%Added
Ameritas Investment Partners, Inc.6,090$309.0K0.01%+510+9.1%Added
E Fund Management Co., Ltd.6,196$315.0K0.01%+6,196New
BNP Paribas Arbitrage, SA6,351$322.7K0.00%−8,586−57.5%Reduced
Raymond James & Associates6,385$324.0K0.00%−455−6.7%Reduced
HC Advisors, LLC6,879$350.0K0.22%−5,181−43.0%Reduced
Oppenheimer & Co Inc7,359$374.0K0.01%+7,359New
MML Investors Services, LLC7,892$401.0K0.00%+10.0%Added
Virtus ETF Advisers LLC8,725$443.0K0.20%00.0%Unchanged
Compagnie Lombard Odier SCmA9,000$457.0K0.01%00.0%Unchanged
Pictet & Cie (Europe) SA9,069$461.0K0.02%+2,734+43.2%Added
Magnetar Financial LLC9,532$484.0K0.01%−3,009−24.0%Reduced
Public Employees Retirement Association of Colorado9,749$495.0K0.00%00.0%Unchanged
HSBC Holdings PLC9,891$504.0K0.00%+5,290+115.0%Added
Winton Group Ltd9,931$505.0K0.03%+9,931New
Cambridge Trust Co10,000$508.0K0.02%00.0%Unchanged
Cornerstone National Bank & Trust Co10,000$508.1K0.22%00.0%Unchanged
Cubist Systematic Strategies, LLC10,304$524.0K0.00%−15,993−60.8%Reduced
Capital Fund Management S.A.10,620$539.6K0.01%+10,620New
Engineers Gate Manager LP10,678$543.0K0.02%+10,678New
Tower Research Capital LLC (TRC)11,066$562.0K0.01%−350−3.1%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)11,627$591.0K0.00%−2,042−14.9%Reduced
Birchview Capital, LP12,000$610.0K0.44%00.0%Unchanged
Amalgamated Bank12,464$633.0K0.00%−87−0.7%Reduced
Amalgamated Financial Corp.12,464$633.0K0.01%+12,464New
Walleye Capital LLC12,687$645.0K0.02%−102,446−89.0%Reduced
Handelsbanken Fonder AB13,400$681.0K0.00%00.0%Unchanged
FORA Capital, LLC14,009$693.0K0.12%+14,009New
Bayesian Capital Management, LP14,000$711.0K0.11%+14,000New
LMR Partners LLP14,219$722.0K0.01%+14,219New
Raymond James Financial Services Advisors, Inc.14,676$746.0K0.00%−11,398−43.7%Reduced
Brookfield Asset Management Inc.14,866$755.0K0.00%+14,866New
Frontier Capital Management Co LLC15,549$790.0K0.01%−107,941−87.4%Reduced
Teacher Retirement System of Texas15,795$803.0K0.00%+1,159+7.9%Added
Janus Henderson Group PLC15,972$811.0K0.00%+65+0.4%Added
American Century Companies Inc16,578$820.0K0.00%+16,578New
Knights of Columbus Asset Advisors LLC16,583$843.0K0.07%+110+0.7%Added
Gsa Capital Partners LLP17,303$879.0K0.12%+17,303New
Twinbeech Capital LP19,123$972.0K0.04%+19,123New
Squarepoint Ops LLC19,298$981.0K0.01%+19,298New
Algert Global LLC20,263$1.03M0.07%+12,896+175.1%Added
Arizona State Retirement System20,707$1.05M0.01%+90+0.4%Added
Regent Investment Management LLC21,309$1.08M0.25%00.0%Unchanged
Laurion Capital Management LP22,000$1.12M0.03%+22,000New
ProShare Advisors LLC23,745$1.21M0.00%−5,406−18.5%Reduced
Principal Financial Group Inc24,304$1.24M0.00%+1,696+7.5%Added
Monashee Investment Management LLC24,555$1.25M0.36%+24,555New
DekaBank Deutsche Girozentrale26,700$1.32M0.00%−16,700−38.5%Reduced
Citigroup Inc26,684$1.36M0.00%−93,004−77.7%Reduced
State Board of Administration of Florida Retirement System26,796$1.36M0.00%00.0%Unchanged
Cinctive Capital Management LP28,054$1.43M0.06%+502+1.8%Added
Allspring Global Investments Holdings, LLC29,069$1.48M0.00%+2,301+8.6%Added
International Biotechnology Trust PLC32,500$1.54M0.68%00.0%Unchanged
Parametric Portfolio Associates LLC32,298$1.64M0.00%−11,435−26.1%Reduced
Allianz Asset Management GmbH32,550$1.65M0.00%+3,200+10.9%Added