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Apellis Pharmaceuticals, Inc.

APLSDelisted May 14, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

Q1 2022 vs. Q4 2021

How the institutions holding Apellis Pharmaceuticals, Inc. changed between Q4 2021 and Q1 2022.

All holders in Q1 2022All holders in Q4 2021

13F holders of APLS: Q4 2021 compared with Q1 2022
MeasureQ4 2021Of which not filed for Q1 2022Q1 2022Change
Holders1873212+28
Shares81.0M177.0K91.0M+10.1M (+12.5%)
Value$3.83B$8.37M$4.62B+$799.1M (+20.9%)

3 institutions that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so the changes leave them out.

New holders (52)

Institutions that held Apellis Pharmaceuticals, Inc. at the end of Q1 2022 but not at the end of Q4 2021.

Institutions new to APLS in Q1 2022
InstitutionSharesValue% of portfolio
Boxer Capital, LLC1,303,700$66.2M3.40%
Marshall Wace, LLP915,163$46.5M0.10%
Adage Capital Partners GP, L.L.C.325,000$16.5M0.03%
Natixis268,100$13.6M0.05%
Caas Capital Management LP250,000$12.7M2.24%
Maven Securities LTD221,400$11.2M2.33%
Avidity Partners Management LP210,000$10.7M0.24%
Artal Group S.A.200,000$10.2M0.43%
Sessa Capital IM, L.P.149,000$7.57M0.46%
Silverarc Capital Management, LLC105,368$5.35M2.91%
DAFNA Capital Management LLC93,935$4.77M1.24%
Sectoral Asset Management Inc69,500$3.53M0.63%
Fred Alger Management, LLC68,783$3.50M0.01%
Man Group plc63,852$3.24M0.01%
Nicholas Investment Partners, LP62,000$3.15M0.22%
First Trust Advisors LP57,809$2.94M0.00%
Tudor Investment Corp Et Al48,840$2.48M0.06%
Employees Retirement System of Texas41,000$2.08M0.02%
Skandinaviska Enskilda Banken AB (publ)37,054$1.88M0.01%
HighVista Strategies LLC36,893$1.88M1.19%
Graham Capital Management, L.P.35,030$1.78M0.08%
Monashee Investment Management LLC24,555$1.25M0.36%
Laurion Capital Management LP22,000$1.12M0.03%
Squarepoint Ops LLC19,298$981.0K0.01%
Twinbeech Capital LP19,123$972.0K0.04%
Gsa Capital Partners LLP17,303$879.0K0.12%
American Century Companies Inc16,578$820.0K0.00%
Brookfield Asset Management Inc.14,866$755.0K0.00%
LMR Partners LLP14,219$722.0K0.01%
Bayesian Capital Management, LP14,000$711.0K0.11%
FORA Capital, LLC14,009$693.0K0.12%
Amalgamated Financial Corp.12,464$633.0K0.01%
Engineers Gate Manager LP10,678$543.0K0.02%
Capital Fund Management S.A.10,620$539.6K0.01%
Winton Group Ltd9,931$505.0K0.03%
Oppenheimer & Co Inc7,359$374.0K0.01%
E Fund Management Co., Ltd.6,196$315.0K0.01%
XTX Topco Ltd5,422$275.0K0.12%
Sandia Investment Management LP5,000$254.0K0.04%
Y-Intercept (Hong Kong) Ltd4,363$222.0K0.05%
Mackenzie Financial Corp4,047$206.0K0.00%
DuPont Capital Management Corp3,167$161.0K0.01%
Simplex Trading, LLC2,967$150.0K0.00%
Lazard Asset Management LLC2,683$136.0K0.00%
CSS LLC1,446$73.0K0.00%
Cowen and Company, LLC1,230$62.0K0.01%
Jefferies Group LLC757$38.5K0.00%
Walleye Trading LLC518$26.0K0.00%
Signaturefd, LLC92$5.00K0.00%
CWM, LLC68$3.00K0.00%
Massmutual Trust Co FSB19$1.00K0.00%
TCWP LLC31$1.00K0.00%

Sold out (24)

Institutions that held Apellis Pharmaceuticals, Inc. at the end of Q4 2021 and filed for Q1 2022 without it.

Institutions that sold out of APLS in Q1 2022
InstitutionShares, Q4 2021Value, Q4 2021
Deerfield Management Company, L.P. (Series C)343,213$16.2M
Tri Locum Partners LP318,269$15.0M
Jacobs Levy Equity Management, Inc310,594$14.7M
Caption Management, LLC220,000$10.4M
Balyasny Asset Management LLC128,514$6.08M
Schonfeld Strategic Advisors LLC118,558$5.61M
Castleark Management LLC53,130$2.51M
Aufman Associates Inc46,751$2.21M
Woodline Partners LP41,199$1.95M
Toronto Dominion Bank38,421$1.82M
HRT Financial LP32,355$1.53M
Two Sigma Advisers, LP30,600$1.45M
ExodusPoint Capital Management, LP13,939$659.0K
Dimensional Fund Advisors LP9,828$465.0K
Connor, Clark & Lunn Investment Management Ltd.9,406$445.0K
Stonnington Group, LLC10,000$412.0K
AlphaCrest Capital Management LLC8,556$405.0K
Allstate Corp6,694$316.0K
Crown Wealth Group, LLC5,040$238.0K
Leonteq Securities AG2,223$105.1K
Eaton Vance Management2,025$96.0K
CoreCap Advisors, LLC300$14.0K
Smith Group Asset Management, LLC80$4.00K
Capital Analysts, LLC57$3.00K

Not filed for Q1 2022 yet (3)

Institutions that held Apellis Pharmaceuticals, Inc. at the end of Q4 2021 and haven't filed a 13F for Q1 2022. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding APLS in Q4 2021 that haven't filed for Q1 2022
InstitutionShares, Q4 2021Value, Q4 2021
Asymmetry Capital Management, L.P.139,445$6.59M
Tygh Capital Management, Inc.37,542$1.77M
Bell Investment Advisors, Inc61$3.00K