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Apellis Pharmaceuticals, Inc.

APLSDelisted
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted in 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q1 2024

Institutional positions in Apellis Pharmaceuticals, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
302
+20 vs. Q4 2023
Shares held
113.1M
−619.3K (−0.5%) vs. Q4 2023
Total value
$6.65B
−$166.2M (−2.4%) vs. Q4 2023
New holders
66
105 more added
Sold out
46
91 more reduced

2 institutions that held it in Q4 2023 haven't filed for Q1 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 302 institutions
Q1 2021: 175 institutionsQ2 2021: 205 institutionsQ3 2021: 181 institutionsQ4 2021: 187 institutionsQ1 2022: 212 institutionsQ2 2022: 212 institutionsQ3 2022: 250 institutionsQ4 2022: 244 institutionsQ1 2023: 282 institutionsQ2 2023: 317 institutionsQ3 2023: 256 institutionsQ4 2023: 284 institutionsQ1 2024: 302 institutionsQ2 2024: 263 institutionsQ3 2024: 265 institutionsQ4 2024: 260 institutionsQ1 2025: 255 institutionsQ2 2025: 247 institutionsQ3 2025: 273 institutionsQ4 2025: 280 institutionsQ1 2026: 324 institutionsQ2 2026: 1 institution
Value heldQ1 2024: $6.97B
Q1 2021: $2.80BQ2 2021: $4.13BQ3 2021: $2.29BQ4 2021: $3.91BQ1 2022: $4.62BQ2 2022: $4.15BQ3 2022: $6.67BQ4 2022: $5.26BQ1 2023: $7.49BQ2 2023: $9.81BQ3 2023: $4.34BQ4 2023: $7.16BQ1 2024: $6.97BQ2 2024: $4.56BQ3 2024: $3.52BQ4 2024: $4.05BQ1 2025: $2.80BQ2 2025: $2.29BQ3 2025: $2.77BQ4 2025: $3.17BQ1 2026: $5.56BQ2 2026: $10.2K
Institutions holding APLS and their total value by quarter
QuarterHoldersValue
Q2 20261$10.2K
Q1 2026324$5.56B
Q4 2025280$3.17B
Q3 2025273$2.77B
Q2 2025247$2.29B
Q1 2025255$2.80B
Q4 2024260$4.05B
Q3 2024265$3.52B
Q2 2024263$4.56B
Q1 2024302$6.97B
Q4 2023284$7.16B
Q3 2023256$4.34B
Q2 2023317$9.81B
Q1 2023282$7.49B
Q4 2022244$5.26B
Q3 2022250$6.67B
Q2 2022212$4.15B
Q1 2022212$4.62B
Q4 2021187$3.91B
Q3 2021181$2.29B
Q2 2021205$4.13B
Q1 2021175$2.80B

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q4 2023.

Institutions holding APLS in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Wellington Management Group LLP15,058,071$885.1M0.16%−1,387,219−8.4%Reduced
EcoR1 Capital, LLC11,357,425$667.6M16.95%+184,357+1.7%Added
Avoro Capital Advisors LLC11,111,111$653.1M7.62%00.0%Unchanged
Vanguard Group Inc9,505,866$558.8M0.01%−49,812−0.5%Reduced
BlackRock Inc.5,494,591$323.0M0.01%+113,338+2.1%Added
T. Rowe Price Investment Management, Inc.4,605,721$270.7M0.17%−1,697,863−26.9%Reduced
Jennison Associates LLC3,240,513$190.5M0.13%−35,409−1.1%Reduced
State Street Corp2,909,528$171.0M0.01%−5,894−0.2%Reduced
Octagon Capital Advisors LP2,806,980$165.0M20.06%00.0%Unchanged
Price T Rowe Associates Inc2,459,246$144.6M0.02%−1,0930.0%Reduced
JPMorgan Chase & Co2,214,309$130.2M0.01%−359,824−14.0%Reduced
FMR LLC2,178,742$128.1M0.01%+86,278+4.1%Added
Assenagon Asset Management S.A.2,023,614$118.9M0.32%−121,390−5.7%Reduced
Boxer Capital, LLC1,726,000$101.5M5.01%00.0%Unchanged
Geode Capital Management, LLC1,689,890$99.4M0.01%+59,248+3.6%Added
Morgan Stanley1,637,618$96.3M0.01%−1,459,523−47.1%Reduced
Deutsche Bank AG1,611,773$94.7M0.04%+754,774+88.1%Added
Artal Group S.A.1,315,282$77.3M1.99%−106,064−7.5%Reduced
OrbiMed Advisors LLC1,297,800$76.3M1.40%+375,600+40.7%Added
Citadel Advisors LLC1,186,082$69.7M0.07%+900,965+316.0%Added
Pictet Asset Management Holding SA1,073,234$63.0M0.07%−271,329−20.2%Reduced
Polar Capital Holdings Plc1,054,440$62.0M0.33%+1,000+0.1%Added
Norges Bank1,007,920$59.2M0.01%+61,707+6.5%Added
Deep Track Capital, LP1,000,000$58.8M1.69%+1,000,000New
Fiera Capital Corp948,437$55.7M0.16%+29,347+3.2%Added
Charles Schwab Investment Management Inc924,562$54.3M0.01%+20,153+2.2%Added
Frazier Life Sciences Management, L.P.885,165$52.0M2.20%00.0%Unchanged
Eagle Asset Management Inc845,533$50.5M0.26%+399,533+89.6%Added
Logos Global Management LP800,000$47.0M4.95%−150,000−15.8%Reduced
Millennium Management LLC785,396$46.2M0.04%+772,869+6,169.6%Added
Invesco Ltd.762,115$44.8M0.01%+243,278+46.9%Added
Bank of America Corp723,444$42.5M0.00%+289,107+66.6%Added
Candriam Luxembourg S.C.A.584,925$34.4M0.22%+247,418+73.3%Added
Iron Triangle Partners LP550,000$32.3M3.35%+550,000New
Ameriprise Financial Inc531,362$31.2M0.01%−34,218−6.1%Reduced
Driehaus Capital Management LLC503,039$29.6M0.29%+21,538+4.5%Added
Voya Investment Management LLC494,692$29.1M0.03%+238,159+92.8%Added
Victory Capital Management Inc491,897$28.9M0.03%−124,375−20.2%Reduced
Bellevue Group AG473,915$27.9M0.42%−347,885−42.3%Reduced
TD Asset Management Inc459,402$27.0M0.03%−23,920−4.9%Reduced
Northern Trust Corp440,456$25.9M0.00%−8,270−1.8%Reduced
First Trust Advisors LP406,483$23.9M0.02%+312,515+332.6%Added
Cormorant Asset Management, LP400,000$23.5M1.04%−225,000−36.0%Reduced
New York State Common Retirement Fund325,926$19.2M0.03%−14,581−4.3%Reduced
Bank of New York Mellon Corp322,922$19.0M0.00%−49,333−13.3%Reduced
Goldman Sachs Group Inc319,476$18.8M0.00%+8,893+2.9%Added
Altitude Crest Partners Inc.287,277$16.9M7.23%+135,077+88.7%Added
Nuveen Asset Management, LLC270,576$15.9M0.00%+560.0%Added
Point72 Asset Management, L.P.267,823$15.7M0.05%+267,823New
Citigroup Inc261,708$15.4M0.02%+175,167+202.4%Added
Ensign Peak Advisors, Inc260,274$15.3M0.03%+14,708+6.0%Added
Prudential Financial Inc245,560$14.4M0.02%−81,000−24.8%Reduced
Susquehanna International Group, LLP244,261$14.4M0.02%−138,571−36.2%Reduced
Fiduciary Trust Co240,986$14.2M0.22%−1,621−0.7%Reduced
Balyasny Asset Management LLC232,243$13.7M0.04%+232,243New
Franklin Resources Inc226,649$13.3M0.00%−3,141−1.4%Reduced
Vestal Point Capital, LP225,000$13.2M1.09%+225,000New
Macquarie Group Ltd221,654$13.0M0.01%−361,775−62.0%Reduced
683 Capital Management, LLC215,000$12.6M1.29%+85,000+65.4%Added
Eventide Asset Management, LLC209,794$12.3M0.19%00.0%Unchanged
Amundi248,483$11.8M0.01%+7,112+2.9%Added
Standard Life Aberdeen plc189,813$11.2M0.02%+20,762+12.3%Added
Woodline Partners LP186,998$11.0M0.10%+774+0.4%Added
Rhenman & Partners Asset Management AB178,395$10.5M0.99%+77,995+77.7%Added
Marshall Wace, LLP171,873$10.1M0.02%−59,003−25.6%Reduced
Affinity Asset Advisors, LLC165,000$9.70M1.58%+90,000+120.0%Added
Redmile Group, LLC155,000$9.11M0.33%+155,000New
Integral Health Asset Management, LLC150,000$8.82M0.87%+150,000New
Rafferty Asset Management, LLC148,801$8.75M0.03%+5,683+4.0%Added
California Public Employees Retirement System145,833$8.57M0.01%00.0%Unchanged
Wells Fargo & Company145,035$8.53M0.00%+12,468+9.4%Added
Swiss National Bank140,300$8.25M0.01%−22,100−13.6%Reduced
Senator Investment Group LP140,000$8.23M0.37%+140,000New
UBS Asset Management Americas Inc139,325$8.19M0.00%−2,443−1.7%Reduced
Bank of Montreal132,937$7.83M0.00%−336,947−71.7%Reduced
Ghost Tree Capital, LLC130,000$7.64M2.46%+130,000New
Jane Street Group, LLC129,009$7.58M0.01%−305,692−70.3%Reduced
Manufacturers Life Insurance Company, The123,330$7.25M0.01%+17,328+16.3%Added
Rhumbline Advisers120,921$7.11M0.01%−12,665−9.5%Reduced
Allspring Global Investments Holdings, LLC115,453$6.79M0.01%+56,178+94.8%Added
UBS Group AG111,292$6.54M0.00%+16,258+17.1%Added
Walleye Capital LLC110,799$6.51M0.07%−36,875−25.0%Reduced
Royal Bank of Canada101,334$5.96M0.00%−16,276−13.8%Reduced
HSBC Holdings PLC98,550$5.79M0.00%+98,550New
Envestnet Asset Management Inc94,605$5.56M0.00%+8,177+9.5%Added
Peregrine Capital Management LLC92,660$5.45M0.16%+92,660New
Lisanti Capital Growth, LLC89,210$5.24M1.28%+42,905+92.7%Added
Legal & General Group Plc85,844$5.05M0.00%+2,373+2.8%Added
Principal Financial Group Inc84,604$4.97M0.00%+60,741+254.5%Added
PFM Health Sciences, LP82,952$4.88M0.24%+82,952New
Credit Suisse AG80,642$4.74M0.00%−4,929−5.8%Reduced
Bleakley Financial Group, LLC78,253$4.60M0.13%+70.0%Added
Simplicity Wealth,LLC78,247$4.60M0.11%+78,247New
Frontier Capital Management Co LLC78,048$4.59M0.04%+78,048New
California State Teachers Retirement System74,370$4.37M0.01%−15,821−17.5%Reduced
Saturn V Capital Management LLC71,463$4.20M1.68%−71,464−50.0%Reduced
HRT Financial LP68,575$4.03M0.02%−7,337−9.7%Reduced
Dimensional Fund Advisors LP68,144$4.01M0.00%+32,577+91.6%Added
Nisa Investment Advisors, LLC67,350$3.96M0.03%00.0%Unchanged
Granahan Investment Management Inc66,597$3.91M0.14%+24,356+57.7%Added