Apellis Pharmaceuticals, Inc.
APLSDelisted- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001492422
Apellis Pharmaceuticals, Inc. was delisted in 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.
13F holders, Q4 2022
Institutional positions in Apellis Pharmaceuticals, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 244
- −4 vs. Q3 2022
- Shares held
- 100.5M
- +3.04M (+3.1%) vs. Q3 2022
- Total value
- $5.20B
- −$1.46B (−21.9%) vs. Q3 2022
- New holders
- 36
- 96 more added
- Sold out
- 40
- 83 more reduced
2 institutions that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1 | $10.2K |
| Q1 2026 | 324 | $5.56B |
| Q4 2025 | 280 | $3.17B |
| Q3 2025 | 273 | $2.77B |
| Q2 2025 | 247 | $2.29B |
| Q1 2025 | 255 | $2.80B |
| Q4 2024 | 260 | $4.05B |
| Q3 2024 | 265 | $3.52B |
| Q2 2024 | 263 | $4.56B |
| Q1 2024 | 302 | $6.97B |
| Q4 2023 | 284 | $7.16B |
| Q3 2023 | 256 | $4.34B |
| Q2 2023 | 317 | $9.81B |
| Q1 2023 | 282 | $7.49B |
| Q4 2022 | 244 | $5.26B |
| Q3 2022 | 250 | $6.67B |
| Q2 2022 | 212 | $4.15B |
| Q1 2022 | 212 | $4.62B |
| Q4 2021 | 187 | $3.91B |
| Q3 2021 | 181 | $2.29B |
| Q2 2021 | 205 | $4.13B |
| Q1 2021 | 175 | $2.80B |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Avoro Capital Advisors LLC | 10,625,000 | $549.4M | 8.21% | +500,000+4.9% | Added |
| Vanguard Group Inc | 9,212,491 | $476.4M | 0.01% | +181,412+2.0% | Added |
| Wellington Management Group LLP | 8,757,661 | $452.9M | 0.09% | −1,199,755−12.0% | Reduced |
| BlackRock Inc. | 7,704,194 | $398.4M | 0.01% | +617,864+8.7% | Added |
| T. Rowe Price Investment Management, Inc. | 5,842,660 | $302.1M | 0.23% | +326,537+5.9% | Added |
| EcoR1 Capital, LLC | 5,183,431 | $268.0M | 8.16% | 00.0% | Unchanged |
| Janus Henderson Group PLC | 3,987,745 | $206.2M | 0.15% | +3,973,609+28,109.9% | Added |
| State Street Corp | 3,471,914 | $179.5M | 0.01% | +514,641+17.4% | Added |
| Octagon Capital Advisors LP | 3,160,000 | $163.4M | 25.44% | +656,941+26.2% | Added |
| Price T Rowe Associates Inc | 2,749,542 | $142.2M | 0.02% | −601,421−17.9% | Reduced |
| Jennison Associates LLC | 2,515,317 | $130.1M | 0.13% | −19,395−0.8% | Reduced |
| JPMorgan Chase & Co | 1,847,309 | $95.5M | 0.01% | +907,262+96.5% | Added |
| Geode Capital Management, LLC | 1,750,001 | $90.5M | 0.01% | +58,799+3.5% | Added |
| Cormorant Asset Management, LP | 1,576,872 | $81.5M | 5.48% | +98,872+6.7% | Added |
| Boxer Capital, LLC | 1,576,000 | $81.5M | 4.30% | +272,300+20.9% | Added |
| Macquarie Group Ltd | 1,461,642 | $75.6M | 0.09% | +40,107+2.8% | Added |
| FMR LLC | 1,460,163 | $75.5M | 0.01% | −10.0% | Reduced |
| Logos Global Management LP | 1,350,000 | $69.8M | 8.18% | +50,000+3.8% | Added |
| Lord, Abbett & Co. LLC | 1,132,623 | $58.6M | 0.21% | +186,097+19.7% | Added |
| Bellevue Group AG | 1,104,217 | $57.1M | 0.76% | +96,773+9.6% | Added |
| Goldman Sachs Group Inc | 1,061,703 | $54.9M | 0.02% | +104,025+10.9% | Added |
| Norges Bank | 1,047,454 | $54.2M | 0.01% | +74,480+7.7% | Added |
| Charles Schwab Investment Management Inc | 982,927 | $50.8M | 0.02% | +34,168+3.6% | Added |
| Artal Group S.A. | 900,000 | $46.5M | 2.68% | −100,000−10.0% | Reduced |
| Northern Trust Corp | 857,121 | $44.3M | 0.01% | +7,933+0.9% | Added |
| Assenagon Asset Management S.A. | 727,729 | $37.6M | 0.15% | −497,607−40.6% | Reduced |
| Westfield Capital Management Co LP | 689,477 | $35.7M | 0.27% | +689,477 | New |
| Fiduciary Trust Co | 552,191 | $28.6M | 0.56% | −8,800−1.6% | Reduced |
| Invesco Ltd. | 500,787 | $25.9M | 0.01% | −102,466−17.0% | Reduced |
| Bank of America Corp | 469,012 | $24.3M | 0.00% | −222,865−32.2% | Reduced |
| Farallon Capital Management, L.L.C. | 450,400 | $23.3M | 0.15% | −27,600−5.8% | Reduced |
| Pictet Asset Management SA | 445,705 | $23.0M | 0.03% | −541,862−54.9% | Reduced |
| Marshall Wace, LLP | 436,423 | $22.6M | 0.06% | +99,696+29.6% | Added |
| Federated Hermes, Inc. | 436,300 | $22.6M | 0.06% | +85,197+24.3% | Added |
| Victory Capital Management Inc | 430,551 | $22.3M | 0.03% | −242,500−36.0% | Reduced |
| Bank of New York Mellon Corp | 405,039 | $20.9M | 0.00% | −3,420−0.8% | Reduced |
| Braidwell LP | 389,596 | $20.1M | 0.68% | +389,596 | New |
| Nuveen Asset Management, LLC | 360,735 | $18.7M | 0.01% | −49,666−12.1% | Reduced |
| Natixis | 345,000 | $17.8M | 0.10% | +63,000+22.3% | Added |
| Eventide Asset Management, LLC | 339,355 | $17.5M | 0.35% | 00.0% | Unchanged |
| Finepoint Capital LP | 334,890 | $17.3M | 5.60% | +68,800+25.9% | Added |
| PFM Health Sciences, LP | 318,422 | $16.5M | 0.70% | +196,542+161.3% | Added |
| Ghost Tree Capital, LLC | 300,000 | $15.5M | 6.62% | +25,000+9.1% | Added |
| Kynam Capital Management, LP | 300,000 | $15.5M | 2.38% | +300,000 | New |
| Morgan Stanley | 299,883 | $15.5M | 0.00% | +76,607+34.3% | Added |
| Driehaus Capital Management LLC | 293,545 | $15.2M | 0.23% | −564,586−65.8% | Reduced |
| Candriam Luxembourg S.C.A. | 278,507 | $14.4M | 0.10% | −65,000−18.9% | Reduced |
| TD Asset Management Inc | 271,620 | $14.0M | 0.02% | −7,096−2.5% | Reduced |
| Deutsche Bank AG | 263,177 | $13.6M | 0.01% | −304,568−53.6% | Reduced |
| Balyasny Asset Management LLC | 256,341 | $13.3M | 0.05% | +209,076+442.3% | Added |
| Nicholas Investment Partners, LP | 248,283 | $12.8M | 1.12% | +53,770+27.6% | Added |
| American Century Companies Inc | 230,824 | $11.9M | 0.01% | +215,553+1,411.5% | Added |
| Barclays PLC | 227,347 | $11.8M | 0.01% | +94,198+70.7% | Added |
| Tri Locum Partners LP | 221,897 | $11.5M | 5.07% | +221,897 | New |
| Acuta Capital Partners, LLC | 217,500 | $11.2M | 6.92% | −336,500−60.7% | Reduced |
| Swiss National Bank | 212,200 | $11.0M | 0.01% | +10,100+5.0% | Added |
| Fred Alger Management, LLC | 206,263 | $10.7M | 0.06% | +71,961+53.6% | Added |
| Rhenman & Partners Asset Management AB | 200,000 | $10.3M | 1.08% | −20,000−9.1% | Reduced |
| California Public Employees Retirement System | 191,964 | $9.93M | 0.01% | +22,282+13.1% | Added |
| Renaissance Technologies LLC | 187,413 | $9.69M | 0.01% | −157,700−45.7% | Reduced |
| Granahan Investment Management Inc | 182,508 | $9.44M | 0.29% | +45,773+33.5% | Added |
| Bleakley Financial Group, LLC | 182,438 | $9.43M | 0.34% | +182,438 | New |
| Saturn V Capital Management LLC | 212,329 | $9.41M | 7.81% | +212,329 | New |
| Prudential Financial Inc | 177,381 | $9.17M | 0.02% | −3,993−2.2% | Reduced |
| 683 Capital Management, LLC | 175,000 | $9.05M | 0.82% | +175,000 | New |
| Lombard Odier Asset Management (Switzerland) SA | 170,353 | $8.81M | 0.70% | +40,776+31.5% | Added |
| Voya Investment Management LLC | 165,306 | $8.55M | 0.01% | −7,375−4.3% | Reduced |
| Rafferty Asset Management, LLC | 164,104 | $8.49M | 0.07% | +61,532+60.0% | Added |
| Ensign Peak Advisors, Inc | 163,430 | $8.45M | 0.02% | +141,100+631.9% | Added |
| Banque Pictet & Cie SA | 158,925 | $8.22M | 0.09% | −10,046−5.9% | Reduced |
| Eversept Partners, LP | 154,796 | $8.00M | 0.76% | +154,796 | New |
| Sectoral Asset Management Inc | 152,340 | $7.88M | 1.52% | +28,350+22.9% | Added |
| Sessa Capital IM, L.P. | 149,000 | $7.70M | 0.47% | 00.0% | Unchanged |
| AXA S.A. | 145,704 | $7.53M | 0.03% | −784−0.5% | Reduced |
| Eagle Asset Management Inc | 136,114 | $6.84M | 0.04% | −5,103−3.6% | Reduced |
| UBS Group AG | 131,897 | $6.82M | 0.00% | +117,258+801.0% | Added |
| Rhumbline Advisers | 130,601 | $6.75M | 0.01% | +7,412+6.0% | Added |
| Allspring Global Investments Holdings, LLC | 126,793 | $6.56M | 0.01% | +2,122+1.7% | Added |
| California State Teachers Retirement System | 113,909 | $5.89M | 0.01% | +3,549+3.2% | Added |
| Alliancebernstein L.P. | 111,100 | $5.74M | 0.00% | −41,824−27.3% | Reduced |
| Man Group plc | 105,784 | $5.47M | 0.02% | −37,601−26.2% | Reduced |
| New York State Common Retirement Fund | 104,420 | $5.40M | 0.01% | −45,534−30.4% | Reduced |
| Royal Bank of Canada | 103,316 | $5.34M | 0.00% | +29,097+39.2% | Added |
| Bank of Montreal | 100,931 | $5.22M | 0.00% | −28,408−22.0% | Reduced |
| Putnam Investments LLC | 97,560 | $5.04M | 0.01% | −8,243−7.8% | Reduced |
| State of Wisconsin Investment Board | 88,158 | $4.56M | 0.01% | +6,968+8.6% | Added |
| Lazard Asset Management LLC | 84,820 | $4.39M | 0.01% | +38,724+84.0% | Added |
| DAFNA Capital Management LLC | 83,446 | $4.31M | 1.22% | +17,500+26.5% | Added |
| Manufacturers Life Insurance Company, The | 82,830 | $4.27M | 0.00% | −10,254−11.0% | Reduced |
| Canada Pension Plan Investment Board | 82,300 | $4.26M | 0.01% | 00.0% | Unchanged |
| Citigroup Inc | 82,100 | $4.25M | 0.01% | −15,732−16.1% | Reduced |
| Legal & General Group Plc | 80,394 | $4.16M | 0.00% | −248−0.3% | Reduced |
| Teachers Retirement System of the State of Kentucky | 78,486 | $4.06M | 0.04% | −25,316−24.4% | Reduced |
| Credit Suisse AG | 76,908 | $3.98M | 0.00% | +380.0% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 76,881 | $3.98M | 0.02% | +71,567+1,346.8% | Added |
| Pier Capital, LLC | 75,217 | $3.89M | 0.64% | +19,833+35.8% | Added |
| UBS Asset Management Americas Inc | 75,086 | $3.88M | 0.00% | +5,928+8.6% | Added |
| Principal Financial Group Inc | 72,982 | $3.77M | 0.00% | +47,936+191.4% | Added |
| Russell Investments Group, Ltd. | 71,875 | $3.72M | 0.01% | −16,265−18.5% | Reduced |
| Woodline Partners LP | 70,651 | $3.65M | 0.05% | +70,651 | New |