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Apellis Pharmaceuticals, Inc.

APLSDelisted May 14, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q4 2022

Institutional positions in Apellis Pharmaceuticals, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
244
−4 vs. Q3 2022
Shares held
100.5M
+3.04M (+3.1%) vs. Q3 2022
Total value
$5.20B
−$1.46B (−21.9%) vs. Q3 2022
New holders
36
96 more added
Sold out
40
83 more reduced

2 institutions that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2022: 244 institutions
Q1 2021: 175 institutionsQ2 2021: 205 institutionsQ3 2021: 181 institutionsQ4 2021: 187 institutionsQ1 2022: 212 institutionsQ2 2022: 212 institutionsQ3 2022: 250 institutionsQ4 2022: 244 institutionsQ1 2023: 282 institutionsQ2 2023: 317 institutionsQ3 2023: 256 institutionsQ4 2023: 284 institutionsQ1 2024: 302 institutionsQ2 2024: 263 institutionsQ3 2024: 265 institutionsQ4 2024: 260 institutionsQ1 2025: 255 institutionsQ2 2025: 247 institutionsQ3 2025: 273 institutionsQ4 2025: 280 institutionsQ1 2026: 324 institutionsQ2 2026: 1 institution
Value heldQ4 2022: $5.20B
Q1 2021: $2.80BQ2 2021: $4.08BQ3 2021: $2.29BQ4 2021: $3.83BQ1 2022: $4.62BQ2 2022: $4.15BQ3 2022: $6.66BQ4 2022: $5.20BQ1 2023: $7.28BQ2 2023: $9.71BQ3 2023: $4.34BQ4 2023: $6.82BQ1 2024: $6.65BQ2 2024: $4.43BQ3 2024: $3.41BQ4 2024: $4.04BQ1 2025: $2.80BQ2 2025: $2.28BQ3 2025: $2.77BQ4 2025: $3.17BQ1 2026: $5.56BQ2 2026: $10.2K
Institutions holding APLS and their total value by quarter
QuarterHoldersValue
Q2 20261$10.2K
Q1 2026324$5.56B
Q4 2025280$3.17B
Q3 2025273$2.77B
Q2 2025247$2.28B
Q1 2025255$2.80B
Q4 2024260$4.04B
Q3 2024265$3.41B
Q2 2024263$4.43B
Q1 2024302$6.65B
Q4 2023284$6.82B
Q3 2023256$4.34B
Q2 2023317$9.71B
Q1 2023282$7.28B
Q4 2022244$5.20B
Q3 2022250$6.66B
Q2 2022212$4.15B
Q1 2022212$4.62B
Q4 2021187$3.83B
Q3 2021181$2.29B
Q2 2021205$4.08B
Q1 2021175$2.80B

Institutions, Q4 2022

Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q3 2022.

Institutions holding APLS in Q4 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Capital Advisors, Ltd. LLC8$00.00%−3−27.3%Reduced
JFS Wealth Advisors, LLC1$520.00%+1New
Institutional & Family Asset Management, LLC4$2070.00%00.0%Unchanged
Baker Avenue Asset Management, LP13$6720.00%+13New
Farther Finance Advisors, LLC13$6720.00%+13New
Massmutual Trust Co FSB19$1.00K0.00%00.0%Unchanged
Ronald Blue Trust, Inc.9$1.00K0.00%+9New
Harvest Group Wealth Management, LLC27$1.40K0.00%+19+237.5%Added
Allworth Financial LP50$2.59K0.00%+3+6.4%Added
Bell Investment Advisors, Inc50$2.59K0.00%00.0%Unchanged
Key Financial Inc38$2.60K0.00%00.0%Unchanged
Parallel Advisors, LLC74$3.83K0.00%−7−8.6%Reduced
Signaturefd, LLC75$3.88K0.00%−3−3.8%Reduced
Hanseatic Management Services Inc85$4.00K0.01%00.0%Unchanged
CWM, LLC75$4.00K0.00%−19−20.2%Reduced
Geneos Wealth Management Inc.100$5.17K0.00%+100New
Gyon Technologies Capital Management, LP110$5.69K0.00%+110New
Ci Investments Inc.139$7.00K0.00%+139New
Rockefeller Capital Management L.P.167$8.00K0.00%+135+421.9%Added
Covestor Ltd169$9.00K0.01%−8−4.5%Reduced
Money Concepts Capital Corp175$9.05K0.00%+175New
Itau Unibanco Holding S.A.179$9.26K0.00%+6+3.5%Added
GWM Advisors LLC200$10.3K0.00%+200New
Cutler Group LP275$14.0K0.00%+175+175.0%Added
Lindbrook Capital, LLC282$14.6K0.00%−16−5.4%Reduced
Baillie Gifford & Co283$14.6K0.00%00.0%Unchanged
CoreCap Advisors, LLC300$15.5K0.00%+300New
TCI Wealth Advisors, Inc.398$20.6K0.00%+90+29.2%Added
Daiwa Securities Group Inc.445$23.0K0.00%+48+12.1%Added
US Bancorp714$36.9K0.00%−3,553−83.3%Reduced
Tower Research Capital LLC (TRC)859$44.0K0.00%−7,686−89.9%Reduced
China Universal Asset Management Co., Ltd.1,123$58.1K0.02%+94+9.1%Added
Harbor Investment Advisory, LLC1,333$68.9K0.01%00.0%Unchanged
S.A. Mason LLC2,360$122.0K0.09%00.0%Unchanged
Union Investments & Development Ltd.3,000$158.2K0.09%00.0%Unchanged
Advisor Group Holdings, Inc.3,249$166.6K0.00%+209+6.9%Added
Nelson, Van Denburg & Campbell Wealth Management Group, LLC3,382$174.9K0.01%+3,382New
MML Investors Services, LLC4,030$208.0K0.00%−201−4.8%Reduced
Jacob Asset Management of New York LLC4,044$209.1K0.25%+1,385+52.1%Added
O'Shaughnessy Asset Management, LLC4,134$213.8K0.00%+9+0.2%Added
IMA Wealth, Inc.4,150$214.6K0.06%00.0%Unchanged
Pearl River Capital, LLC4,208$217.6K0.04%+297+7.6%Added
Compagnie Lombard Odier SCmA4,500$233.0K0.01%00.0%Unchanged
Great West Life Assurance Co4,518$235.0K0.00%+430+10.5%Added
Cim Investment Mangement Inc4,581$236.9K0.09%+1,238+37.0%Added
Cowen and Company, LLC5,000$258.6K0.03%−14,000−73.7%Reduced
Citadel Advisors LLC5,269$272.5K0.00%−42,892−89.1%Reduced
Xponance, Inc.5,369$277.6K0.00%+114+2.2%Added
Stelac Advisory Services LLC5,520$285.4K0.13%+5,520New
HC Advisors, LLC5,725$296.0K0.20%−35,640−86.2%Reduced
Virtus ETF Advisers LLC5,743$297.0K0.16%−313−5.2%Reduced
Metropolitan Life Insurance Co5,763$298.0K0.01%+131+2.3%Added
NJ State Employees Deferred Compensation Plan6,000$310.3K0.05%+6,000New
JustInvest LLC6,221$321.7K0.01%+6,221New
Henshaw Capital LLC6,892$356.4K0.02%00.0%Unchanged
Polar Capital Holdings Plc6,900$356.8K0.00%00.0%Unchanged
Legato Capital Management LLC6,961$360.0K0.07%+6,961New
Boulder Hill Capital Management LP7,100$367.1K0.30%+7,100New
Ameritas Investment Partners, Inc.7,353$372.1K0.01%00.0%Unchanged
Stifel Financial Corp7,210$372.8K0.00%+558+8.4%Added
Pictet & Cie (Europe) SA7,262$375.5K0.02%−35−0.5%Reduced
Oppenheimer & Co Inc7,515$388.6K0.01%+132+1.8%Added
Keybank National Association8,373$433.0K0.00%00.0%Unchanged
E Fund Management Co., Ltd.8,604$445.0K0.04%+1,554+22.0%Added
Illinois Municipal Retirement Fund8,694$450.0K0.01%+8,694New
Harbour Capital Advisors, LLC9,487$477.0K0.16%+2,717+40.1%Added
Hennion & Walsh Asset Management, Inc.9,418$487.0K0.03%−48,299−83.7%Reduced
Public Employees Retirement Association of Colorado9,749$504.0K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC9,848$509.0K0.00%−15−0.2%Reduced
Cambridge Trust Co10,000$517.0K0.02%00.0%Unchanged
Moore Capital Management, LP10,000$517.1K0.01%−169,958−94.4%Reduced
Mackenzie Financial Corp10,302$532.7K0.00%−35,849−77.7%Reduced
STRS Ohio10,400$537.0K0.00%−2,500−19.4%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)10,635$549.9K0.00%−880−7.6%Reduced
SEI Investments Co10,796$558.3K0.00%−45,125−80.7%Reduced
Stock Yards Bank & Trust Co11,215$580.0K0.02%+1,715+18.1%Added
Raymond James Financial Services Advisors, Inc.11,418$590.4K0.00%−262−2.2%Reduced
Crown Wealth Group, LLC11,814$610.9K0.57%+6,840+137.5%Added
Duality Advisers, LP11,823$611.4K0.07%−26,234−68.9%Reduced
Birchview Capital, LP12,000$621.0K0.44%00.0%Unchanged
Handelsbanken Fonder AB12,000$621.0K0.00%+300+2.6%Added
Hillsdale Investment Management Inc.12,600$651.5K0.06%00.0%Unchanged
Profund Advisors LLC12,722$657.9K0.04%+315+2.5%Added
Capital Fund Management S.A.12,884$666.2K0.01%+12,884New
D. E. Shaw & Co., Inc.12,898$667.0K0.00%−184,466−93.5%Reduced
Capital Impact Advisors, LLC13,959$721.8K0.71%00.0%Unchanged
Jane Street Group, LLC14,021$725.0K0.00%−2,977−17.5%Reduced
Creative Planning14,087$728.4K0.00%+8,016+132.0%Added
Raymond James & Associates14,437$746.5K0.00%+405+2.9%Added
ExodusPoint Capital Management, LP14,792$765.0K0.01%+14,792New
Virginia Retirement Systems Et Al15,000$775.6K0.01%−1,000−6.3%Reduced
DuPont Capital Management Corp15,177$784.8K0.04%+8,833+139.2%Added
Amalgamated Bank15,403$796.0K0.01%+231+1.5%Added
Panagora Asset Management Inc16,231$839.3K0.01%−3,900−19.4%Reduced
Schonfeld Strategic Advisors LLC16,400$848.0K0.01%−68,289−80.6%Reduced
Wells Fargo & Company16,945$876.2K0.00%−2,653−13.5%Reduced
Caption Management, LLC17,000$879.1K0.15%+17,000New
AQR Capital Management LLC17,191$888.9K0.00%+8,792+104.7%Added
Knights of Columbus Asset Advisors LLC18,691$966.5K0.10%−367−1.9%Reduced
Millennium Management LLC19,636$1.01M0.00%−238,233−92.4%Reduced