Apellis Pharmaceuticals, Inc.
APLSDelisted- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001492422
Apellis Pharmaceuticals, Inc. was delisted in 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.
13F holders, Q1 2025
Institutional positions in Apellis Pharmaceuticals, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 255
- −2 vs. Q4 2024
- Shares held
- 128.0M
- +1.77M (+1.4%) vs. Q4 2024
- Total value
- $2.80B
- −$1.23B (−30.5%) vs. Q4 2024
- New holders
- 50
- 90 more added
- Sold out
- 52
- 76 more reduced
3 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1 | $10.2K |
| Q1 2026 | 324 | $5.56B |
| Q4 2025 | 280 | $3.17B |
| Q3 2025 | 273 | $2.77B |
| Q2 2025 | 247 | $2.29B |
| Q1 2025 | 255 | $2.80B |
| Q4 2024 | 260 | $4.05B |
| Q3 2024 | 265 | $3.52B |
| Q2 2024 | 263 | $4.56B |
| Q1 2024 | 302 | $6.97B |
| Q4 2023 | 284 | $7.16B |
| Q3 2023 | 256 | $4.34B |
| Q2 2023 | 317 | $9.81B |
| Q1 2023 | 282 | $7.49B |
| Q4 2022 | 244 | $5.26B |
| Q3 2022 | 250 | $6.67B |
| Q2 2022 | 212 | $4.15B |
| Q1 2022 | 212 | $4.62B |
| Q4 2021 | 187 | $3.91B |
| Q3 2021 | 181 | $2.29B |
| Q2 2021 | 205 | $4.13B |
| Q1 2021 | 175 | $2.80B |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Wellington Management Group LLP | 12,303,252 | $269.1M | 0.05% | +502,403+4.3% | Added |
| Avoro Capital Advisors LLC | 12,222,222 | $267.3M | 4.17% | 00.0% | Unchanged |
| EcoR1 Capital, LLC | 11,895,808 | $260.2M | 15.45% | +4,9650.0% | Added |
| Vanguard Group Inc | 10,130,356 | $221.6M | 0.00% | +84,331+0.8% | Added |
| Morgan Stanley | 9,626,123 | $210.5M | 0.02% | −1,1040.0% | Reduced |
| BlackRock, Inc. | 6,329,598 | $138.4M | 0.00% | −148,391−2.3% | Reduced |
| Deep Track Capital, LP | 5,000,000 | $109.3M | 3.54% | +725,079+17.0% | Added |
| AQR Capital Management LLC | 4,077,419 | $89.2M | 0.09% | +2,220,977+119.6% | Added |
| State Street Corp | 3,941,405 | $86.2M | 0.00% | −583,750−12.9% | Reduced |
| UBS Group AG | 3,272,194 | $71.6M | 0.02% | +685,455+26.5% | Added |
| Bank of America Corp | 3,131,436 | $68.5M | 0.01% | +1,451,223+86.4% | Added |
| Siren, L.L.C. | 2,578,396 | $56.4M | 3.18% | −237,862−8.4% | Reduced |
| Jennison Associates LLC | 2,477,531 | $54.2M | 0.04% | −282,873−10.2% | Reduced |
| Octagon Capital Advisors LP | 2,094,000 | $45.8M | 9.01% | −912,980−30.4% | Reduced |
| Geode Capital Management, LLC | 1,950,046 | $42.7M | 0.00% | +111,094+6.0% | Added |
| Deutsche Bank AG | 1,776,576 | $38.9M | 0.02% | −1,801−0.1% | Reduced |
| Braidwell LP | 1,652,334 | $36.1M | 1.27% | −446,532−21.3% | Reduced |
| Suvretta Capital Management, LLC | 1,646,615 | $36.0M | 1.46% | +853,428+107.6% | Added |
| Polar Capital Holdings Plc | 1,577,175 | $34.5M | 0.21% | 00.0% | Unchanged |
| Norges Bank | 1,573,601 | $34.4M | 0.00% | +487,358+44.9% | Added |
| FMR LLC | 1,503,209 | $32.9M | 0.00% | −624,456−29.3% | Reduced |
| OrbiMed Advisors LLC | 1,432,300 | $31.3M | 0.75% | +1,432,300 | New |
| BNP Paribas Arbitrage, SA | 1,110,709 | $24.3M | 0.02% | +259,886+30.5% | Added |
| Canada Pension Plan Investment Board | 1,048,700 | $22.9M | 0.02% | +1,013,500+2,879.3% | Added |
| Man Group plc | 1,027,792 | $22.5M | 0.07% | +978,500+1,985.1% | Added |
| Charles Schwab Investment Management Inc | 964,499 | $21.1M | 0.00% | −32,249−3.2% | Reduced |
| Royal Bank of Canada | 794,935 | $17.4M | 0.00% | −723,892−47.7% | Reduced |
| National Bank of Canada | 782,701 | $17.1M | 0.02% | −602,899−43.5% | Reduced |
| Boxer Capital Management, LLC | 713,000 | $15.6M | 4.69% | −713,000−50.0% | Reduced |
| Natixis | 655,027 | $14.8M | 0.09% | −215,600−24.8% | Reduced |
| Invesco Ltd. | 641,397 | $14.0M | 0.00% | +37,741+6.3% | Added |
| Jefferies Financial Group Inc. | 599,255 | $13.1M | 0.23% | +257,894+75.5% | Added |
| Northern Trust Corp | 518,694 | $11.3M | 0.00% | −28,582−5.2% | Reduced |
| Nuveen, LLC | 492,238 | $10.8M | 0.00% | +492,238 | New |
| Ameriprise Financial Inc | 466,661 | $10.2M | 0.00% | −416,140−47.1% | Reduced |
| Millennium Management LLC | 451,973 | $9.88M | 0.01% | −123,517−21.5% | Reduced |
| Squarepoint Ops LLC | 442,793 | $9.68M | 0.02% | +275,831+165.2% | Added |
| JPMorgan Chase & Co | 423,800 | $9.27M | 0.00% | +12,251+3.0% | Added |
| Citigroup Inc | 416,619 | $9.11M | 0.01% | +224,458+116.8% | Added |
| Trexquant Investment LP | 384,922 | $8.42M | 0.10% | +181,914+89.6% | Added |
| SG Americas Securities, LLC | 366,144 | $8.01M | 0.03% | +313,743+598.7% | Added |
| Pictet Asset Management Holding SA | 314,842 | $7.62M | 0.01% | −33,012−9.5% | Reduced |
| Amundi | 329,582 | $7.42M | 0.00% | 00.0% | Unchanged |
| Algert Global LLC | 338,613 | $7.41M | 0.18% | +56,328+20.0% | Added |
| 683 Capital Management, LLC | 333,000 | $7.28M | 0.74% | −27,000−7.5% | Reduced |
| Bank of New York Mellon Corp | 329,173 | $7.20M | 0.00% | −5,243−1.6% | Reduced |
| Balyasny Asset Management LLC | 324,487 | $7.10M | 0.02% | −419,707−56.4% | Reduced |
| Walleye Capital LLC | 317,442 | $6.94M | 0.08% | −77,381−19.6% | Reduced |
| Hudson Bay Capital Management LP | 310,700 | $6.80M | 0.04% | −34,300−9.9% | Reduced |
| Goldman Sachs Group Inc | 307,709 | $6.73M | 0.00% | +64,742+26.6% | Added |
| Ieq Capital, LLC | 291,858 | $6.38M | 0.05% | +165,148+130.3% | Added |
| Schroder Investment Management Group | 253,109 | $6.14M | 0.01% | +33,726+15.4% | Added |
| Jump Financial, LLC | 265,593 | $5.81M | 0.09% | +265,593 | New |
| Two Sigma Investments, LP | 262,904 | $5.75M | 0.01% | +262,904 | New |
| Jane Street Group, LLC | 256,092 | $5.60M | 0.01% | +160,107+166.8% | Added |
| Voloridge Investment Management, LLC | 253,790 | $5.55M | 0.02% | −92,095−26.6% | Reduced |
| ExodusPoint Capital Management, LP | 250,414 | $5.48M | 0.07% | +250,414 | New |
| Edgestream Partners, L.P. | 241,287 | $5.28M | 0.18% | +131,404+119.6% | Added |
| Citadel Advisors LLC | 224,096 | $4.90M | 0.00% | +111,673+99.3% | Added |
| UBS Asset Management Americas Inc | 222,634 | $4.87M | 0.00% | +9,747+4.6% | Added |
| Woodline Partners LP | 218,850 | $4.79M | 0.03% | +29,373+15.5% | Added |
| Prudential Financial Inc | 217,880 | $4.77M | 0.01% | +19,820+10.0% | Added |
| Aquatic Capital Management LLC | 215,876 | $4.72M | 0.12% | +86,667+67.1% | Added |
| Victory Capital Management Inc | 215,152 | $4.71M | 0.00% | −347,117−61.7% | Reduced |
| Macquarie Group Ltd | 204,803 | $4.48M | 0.01% | +3,736+1.9% | Added |
| Fiduciary Trust Co | 203,336 | $4.45M | 0.06% | −26,465−11.5% | Reduced |
| First Trust Advisors LP | 199,209 | $4.36M | 0.00% | +173,564+676.8% | Added |
| PDT Partners, LLC | 195,165 | $4.27M | 0.30% | +57,471+41.7% | Added |
| Two Sigma Advisers, LP | 191,800 | $4.19M | 0.01% | +191,800 | New |
| Barclays PLC | 191,237 | $4.18M | 0.00% | +31,672+19.8% | Added |
| ING Groep NV | 184,200 | $4.03M | 0.03% | +184,200 | New |
| Schonfeld Strategic Advisors LLC | 181,400 | $3.97M | 0.03% | +181,400 | New |
| Sphera Funds Management Ltd. | 181,346 | $3.97M | 0.98% | −24,905−12.1% | Reduced |
| Rafferty Asset Management, LLC | 180,134 | $3.94M | 0.02% | −61,340−25.4% | Reduced |
| Granahan Investment Management Inc | 175,696 | $3.84M | 0.19% | +21,278+13.8% | Added |
| Toronto Dominion Bank | 162,190 | $3.55M | 0.01% | −834,863−83.7% | Reduced |
| Candriam Luxembourg S.C.A. | 159,054 | $3.48M | 0.02% | −380,548−70.5% | Reduced |
| Bank of Montreal | 158,573 | $3.47M | 0.00% | +77,582+95.8% | Added |
| Alyeska Investment Group, L.P. | 150,000 | $3.28M | 0.01% | +150,000 | New |
| Swiss National Bank | 132,600 | $2.90M | 0.00% | −11,100−7.7% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 131,895 | $2.88M | 0.01% | +118,417+878.6% | Added |
| Old West Investment Management, LLC | 128,192 | $2.80M | 1.01% | +14,569+12.8% | Added |
| California Public Employees Retirement System | 126,706 | $2.77M | 0.00% | +470.0% | Added |
| Voya Investment Management LLC | 125,401 | $2.74M | 0.00% | +2,250+1.8% | Added |
| Rhumbline Advisers | 124,454 | $2.72M | 0.00% | −1,106−0.9% | Reduced |
| Steward Partners Investment Advisory, LLC | 122,175 | $2.67M | 0.02% | +7,130+6.2% | Added |
| Verition Fund Management LLC | 110,510 | $2.42M | 0.01% | +60,100+119.2% | Added |
| HighVista Strategies LLC | 108,714 | $2.38M | 0.92% | 00.0% | Unchanged |
| CWM, LLC | 98,258 | $2.15M | 0.01% | +53,663+120.3% | Added |
| State Board of Administration of Florida Retirement System | 91,818 | $2.01M | 0.00% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 90,700 | $1.98M | 0.00% | −267,878−74.7% | Reduced |
| State of Wisconsin Investment Board | 84,615 | $1.85M | 0.00% | +4,233+5.3% | Added |
| Rock Springs Capital Management LP | 80,000 | $1.75M | 0.10% | 00.0% | Unchanged |
| Legal & General Group Plc | 79,070 | $1.73M | 0.00% | −7,701−8.9% | Reduced |
| Ikarian Capital, LLC | 75,000 | $1.64M | 0.53% | +71,406+1,986.8% | Added |
| Assenagon Asset Management S.A. | 74,325 | $1.63M | 0.00% | +44,332+147.8% | Added |
| Bleakley Financial Group, LLC | 73,137 | $1.60M | 0.05% | −368−0.5% | Reduced |
| Wealth Enhancement Advisory Services, LLC | 70,159 | $1.53M | 0.00% | +36,565+108.8% | Added |
| California State Teachers Retirement System | 59,778 | $1.31M | 0.00% | −10,910−15.4% | Reduced |
| DekaBank Deutsche Girozentrale | 55,000 | $1.29M | 0.00% | 00.0% | Unchanged |