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Apellis Pharmaceuticals, Inc.

APLSDelisted May 14, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

Q1 2025 vs. Q4 2024

How the institutions holding Apellis Pharmaceuticals, Inc. changed between Q4 2024 and Q1 2025.

All holders in Q1 2025All holders in Q4 2024

13F holders of APLS: Q4 2024 compared with Q1 2025
MeasureQ4 2024Of which not filed for Q1 2025Q1 2025Change
Holders2603255−2
Shares126.7M491.2K128.0M+1.77M (+1.4%)
Value$4.04B$15.7M$2.80B−$1.23B (−30.5%)

3 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so the changes leave them out.

New holders (50)

Institutions that held Apellis Pharmaceuticals, Inc. at the end of Q1 2025 but not at the end of Q4 2024.

Institutions new to APLS in Q1 2025
InstitutionSharesValue% of portfolio
OrbiMed Advisors LLC1,432,300$31.3M0.75%
Nuveen, LLC492,238$10.8M0.00%
Jump Financial, LLC265,593$5.81M0.09%
Two Sigma Investments, LP262,904$5.75M0.01%
ExodusPoint Capital Management, LP250,414$5.48M0.07%
Two Sigma Advisers, LP191,800$4.19M0.01%
ING Groep NV184,200$4.03M0.03%
Schonfeld Strategic Advisors LLC181,400$3.97M0.03%
Alyeska Investment Group, L.P.150,000$3.28M0.01%
Tudor Investment Corp Et Al52,980$1.16M0.01%
Engineers Gate Manager LP42,172$922.3K0.02%
Bayesian Capital Management, LP37,900$828.9K0.14%
Voleon Capital Management LP30,191$660.3K0.05%
Group One Trading, L.P.30,041$657.0K0.03%
Y-Intercept (Hong Kong) Ltd29,577$646.8K0.04%
Bridgefront Capital, LLC29,070$635.8K0.18%
Parallax Volatility Advisers, L.P.28,350$620.0K0.02%
Graham Capital Management, L.P.28,136$615.3K0.02%
Virginia Retirement Systems Et Al24,665$539.4K0.00%
Boothbay Fund Management, LLC22,997$502.9K0.02%
GWN Securities Inc.27,190$454.1K0.03%
111 Capital16,836$368.2K0.07%
Buckingham Strategic Partners16,567$362.7K0.01%
Universal- Beteiligungs- und Servicegesellschaft mbH16,159$353.4K0.00%
Fox Run Management, L.L.C.15,712$343.6K0.05%
Aigen Investment Management, LP15,621$341.6K0.05%
Mariner, LLC13,004$284.4K0.00%
Diversified Trust Co12,878$281.6K0.01%
Caption Management, LLC12,000$262.4K0.01%
Teza Capital Management LLC11,855$259.3K0.12%
Jain Global LLC11,719$256.3K0.01%
Virtus Investment Advisers, Inc.10,967$239.8K0.07%
Lecap Asset Management Ltd10,759$235.3K0.05%
Kaufman Rossin Wealth, LLC9,577$209.4K0.15%
Lazard Asset Management LLC3,553$77.0K0.00%
Clearstead Advisors, LLC1,811$39.6K0.00%
Headlands Technologies LLC812$17.8K0.00%
Coldstream Capital Management Inc591$12.9K0.00%
Clear Street Markets LLC278$6.08K0.00%
Sofos Investments, Inc.100$2.19K0.00%
Boston Private Wealth LLC94$2.06K0.00%
Atlantic Trust, LLC51$1.12K0.00%
Capital Analysts, LLC57$1.00K0.00%
Private Wealth Management Group, LLC42$9190.00%
South State Corp.20$4380.00%
CVA Family Office, LLC20$4370.00%
CoreCap Advisors, LLC10$2190.00%
Creative Financial Designs Inc5$1090.00%
Hantz Financial Services, Inc.6$00.00%
Avion Wealth15$00.00%

Sold out (52)

Institutions that held Apellis Pharmaceuticals, Inc. at the end of Q4 2024 and filed for Q1 2025 without it.

Institutions that sold out of APLS in Q1 2025
InstitutionShares, Q4 2024Value, Q4 2024
CIBC World Markets Corp1,285,300$41.0M
Point72 Asset Management, L.P.1,267,958$40.5M
Logos Global Management LP500,000$16.0M
Integral Health Asset Management, LLC420,000$13.4M
MUFG Securities EMEA plc298,000$9.51M
Renaissance Technologies LLC271,913$8.68M
Intrinsic Edge Capital Management LLC200,000$6.38M
Point72 Europe (London) LLP192,694$6.15M
Cubist Systematic Strategies, LLC191,687$6.12M
Capital Fund Management S.A.121,433$3.87M
Exome Asset Management LLC119,467$3.81M
Banque Pictet & Cie SA97,299$3.10M
Cinctive Capital Management LP86,991$2.78M
Fieldview Capital Management, LLC61,405$1.96M
Affinity Asset Advisors, LLC50,000$1.60M
TD Asset Management Inc38,692$1.23M
Readystate Asset Management LP35,561$1.13M
Savant Capital, LLC31,525$1.01M
Prelude Capital Management, LLC31,255$997.3K
Sippican Capital Advisors20,753$662.2K
D. E. Shaw & Co., Inc.20,000$638.2K
Syon Capital LLC19,455$620.8K
Creative Planning16,214$517.4K
Vident Advisory, LLC14,564$464.7K
Entropy Technologies, LP13,960$445.5K
Campbell & CO Investment Adviser LLC11,258$359.2K
Virtus ETF Advisers LLC10,680$340.8K
Dynamic Technology Lab Private Ltd9,937$318.0K
XTX Topco Ltd9,785$312.2K
Inceptionr LLC9,217$294.1K
Principal Financial Group Inc9,094$290.2K
DnB Asset Management AS8,853$282.5K
Kovitz Investment Group Partners, LLC8,394$267.9K
KPP Advisory Services LLC8,151$260.1K
Point72 (DIFC) Ltd8,009$255.6K
Gsa Capital Partners LLP7,835$250.0K
JustInvest LLC7,832$249.9K
Corton Capital Inc.7,595$242.4K
Virtu Financial LLC7,157$228.0K
Nomura Holdings Inc7,000$223.4K
M&T Bank Corp6,768$215.8K
Quadrant Capital Group LLC261$8.33K
Colonial Trust Co258$8.23K
Nelson, Van Denburg & Campbell Wealth Management Group, LLC220$7.02K
Harbor Investment Advisory, LLC200$6.38K
Sachetta, LLC82$2.62K
Coppell Advisory Solutions LLC79$2.52K
GWM Advisors LLC50$1.60K
Massmutual Trust Co FSB34$1.08K
WealthTrak Capital Management LLC10$320
Activest Wealth Management1$32
Capital Advisors, Ltd. LLC6$0

Not filed for Q1 2025 yet (3)

Institutions that held Apellis Pharmaceuticals, Inc. at the end of Q4 2024 and haven't filed a 13F for Q1 2025. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding APLS in Q4 2024 that haven't filed for Q1 2025
InstitutionShares, Q4 2024Value, Q4 2024
Nuveen Asset Management, LLC491,107$15.7M
Financial Gravity Companies, Inc.100$3.19K
Global Retirement Partners, LLC24$766