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Apellis Pharmaceuticals, Inc.

APLS2026/5/14 下市
產業
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. 已在 2026/5/14 下市；內部人最後一份 Form 4 在 2026/5/14 申報；2026 年第 1 季末有 324 家機構在 13F 申報持有，市值合計 $55.6 億；大師中只有索羅斯基金管理持有。

2025 年第 1 季與 2024 年第 4 季比較

持有 Apellis Pharmaceuticals, Inc. 的機構從 2024 年第 4 季到 2025 年第 1 季的變化。

2025 年第 1 季全部持有人2024 年第 4 季全部持有人

APLS 的 13F 持有人：2024 年第 4 季與 2025 年第 1 季比較
項目2024 年第 4 季其中尚未申報 2025 年第 1 季2025 年第 1 季變化
持有家數2603255−2
股數1.27 億49.1 萬1.28 億+177.0 萬 (+1.4%)
市值$40.4 億$1,568 萬$28.0 億−$12.3 億 (−30.5%)

3 家機構在 2024 年第 4 季持有、還沒有申報 2025 年第 1 季：沒申報不算清倉，所以變化不計入它們。

新進機構（50 家）

2025 年第 1 季季末持有 Apellis Pharmaceuticals, Inc.、2024 年第 4 季季末沒有持有的機構。

2025 年第 1 季新進 APLS 的機構
機構股數市值佔組合 %
OrbiMed Advisors LLC1,432,300$3,132 萬0.75%
Nuveen, LLC492,238$1,077 萬0.00%
Jump Financial, LLC265,593$580.9 萬0.09%
Two Sigma Investments, LP262,904$575.0 萬0.01%
ExodusPoint Capital Management, LP250,414$547.7 萬0.07%
Two Sigma Advisers, LP191,800$419.5 萬0.01%
ING Groep NV184,200$402.8 萬0.03%
Schonfeld Strategic Advisors LLC181,400$396.7 萬0.03%
Alyeska Investment Group, L.P.150,000$328.1 萬0.01%
Tudor Investment Corp Et Al52,980$115.9 萬0.01%
Engineers Gate Manager LP42,172$92.2 萬0.02%
Bayesian Capital Management, LP37,900$82.9 萬0.14%
Voleon Capital Management LP30,191$66.0 萬0.05%
Group One Trading, L.P.30,041$65.7 萬0.03%
Y-Intercept (Hong Kong) Ltd29,577$64.7 萬0.04%
Bridgefront Capital, LLC29,070$63.6 萬0.18%
Parallax Volatility Advisers, L.P.28,350$62.0 萬0.02%
Graham Capital Management, L.P.28,136$61.5 萬0.02%
Virginia Retirement Systems Et Al24,665$53.9 萬0.00%
Boothbay Fund Management, LLC22,997$50.3 萬0.02%
GWN Securities Inc.27,190$45.4 萬0.03%
111 Capital16,836$36.8 萬0.07%
Buckingham Strategic Partners16,567$36.3 萬0.01%
Universal- Beteiligungs- und Servicegesellschaft mbH16,159$35.3 萬0.00%
Fox Run Management, L.L.C.15,712$34.4 萬0.05%
Aigen Investment Management, LP15,621$34.2 萬0.05%
Mariner, LLC13,004$28.4 萬0.00%
Diversified Trust Co12,878$28.2 萬0.01%
Caption Management, LLC12,000$26.2 萬0.01%
Teza Capital Management LLC11,855$25.9 萬0.12%
Jain Global LLC11,719$25.6 萬0.01%
Virtus Investment Advisers, Inc.10,967$24.0 萬0.07%
Lecap Asset Management Ltd10,759$23.5 萬0.05%
Kaufman Rossin Wealth, LLC9,577$20.9 萬0.15%
Lazard Asset Management LLC3,553$7.70 萬0.00%
Clearstead Advisors, LLC1,811$3.96 萬0.00%
Headlands Technologies LLC812$1.78 萬0.00%
Coldstream Capital Management Inc591$1.29 萬0.00%
Clear Street Markets LLC278$6,0800.00%
Sofos Investments, Inc.100$2,1870.00%
Boston Private Wealth LLC94$2,0560.00%
Atlantic Trust, LLC51$1,1160.00%
Capital Analysts, LLC57$1,0000.00%
Private Wealth Management Group, LLC42$9190.00%
South State Corp.20$4380.00%
CVA Family Office, LLC20$4370.00%
CoreCap Advisors, LLC10$2190.00%
Creative Financial Designs Inc5$1090.00%
Hantz Financial Services, Inc.6$00.00%
Avion Wealth15$00.00%

清倉機構（52 家）

2024 年第 4 季季末持有 Apellis Pharmaceuticals, Inc.、2025 年第 1 季有申報但已經沒有持有的機構。

2025 年第 1 季清倉 APLS 的機構
機構2024 年第 4 季股數2024 年第 4 季市值
CIBC World Markets Corp1,285,300$4,101 萬
Point72 Asset Management, L.P.1,267,958$4,046 萬
Logos Global Management LP500,000$1,596 萬
Integral Health Asset Management, LLC420,000$1,340 萬
MUFG Securities EMEA plc298,000$950.9 萬
Renaissance Technologies LLC271,913$867.7 萬
Intrinsic Edge Capital Management LLC200,000$638.2 萬
Point72 Europe (London) LLP192,694$614.9 萬
Cubist Systematic Strategies, LLC191,687$611.7 萬
Capital Fund Management S.A.121,433$387.5 萬
Exome Asset Management LLC119,467$381.2 萬
Banque Pictet & Cie SA97,299$310.5 萬
Cinctive Capital Management LP86,991$277.6 萬
Fieldview Capital Management, LLC61,405$195.9 萬
Affinity Asset Advisors, LLC50,000$159.6 萬
TD Asset Management Inc38,692$123.5 萬
Readystate Asset Management LP35,561$113.5 萬
Savant Capital, LLC31,525$100.6 萬
Prelude Capital Management, LLC31,255$99.7 萬
Sippican Capital Advisors20,753$66.2 萬
D. E. Shaw & Co., Inc.20,000$63.8 萬
Syon Capital LLC19,455$62.1 萬
Creative Planning16,214$51.7 萬
Vident Advisory, LLC14,564$46.5 萬
Entropy Technologies, LP13,960$44.5 萬
Campbell & CO Investment Adviser LLC11,258$35.9 萬
Virtus ETF Advisers LLC10,680$34.1 萬
Dynamic Technology Lab Private Ltd9,937$31.8 萬
XTX Topco Ltd9,785$31.2 萬
Inceptionr LLC9,217$29.4 萬
Principal Financial Group Inc9,094$29.0 萬
DnB Asset Management AS8,853$28.2 萬
Kovitz Investment Group Partners, LLC8,394$26.8 萬
KPP Advisory Services LLC8,151$26.0 萬
Point72 (DIFC) Ltd8,009$25.6 萬
Gsa Capital Partners LLP7,835$25.0 萬
JustInvest LLC7,832$25.0 萬
Corton Capital Inc.7,595$24.2 萬
Virtu Financial LLC7,157$22.8 萬
Nomura Holdings Inc7,000$22.3 萬
M&T Bank Corp6,768$21.6 萬
Quadrant Capital Group LLC261$8,329
Colonial Trust Co258$8,233
Nelson, Van Denburg & Campbell Wealth Management Group, LLC220$7,020
Harbor Investment Advisory, LLC200$6,382
Sachetta, LLC82$2,617
Coppell Advisory Solutions LLC79$2,520
GWM Advisors LLC50$1,596
Massmutual Trust Co FSB34$1,085
WealthTrak Capital Management LLC10$320
Activest Wealth Management1$32
Capital Advisors, Ltd. LLC6$0

尚未申報 2025 年第 1 季的機構（3 家）

2024 年第 4 季季末持有 Apellis Pharmaceuticals, Inc.、還沒有申報 2025 年第 1 季 13F 的機構。沒申報不代表賣出，所以不算清倉。

2024 年第 4 季持有 APLS、尚未申報 2025 年第 1 季的機構
機構2024 年第 4 季股數2024 年第 4 季市值
Nuveen Asset Management, LLC491,107$1,567 萬
Financial Gravity Companies, Inc.100$3,191
Global Retirement Partners, LLC24$766