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Apellis Pharmaceuticals, Inc.

APLSDelisted May 14, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q4 2022

Institutional positions in Apellis Pharmaceuticals, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
244
−4 vs. Q3 2022
Shares held
100.5M
+3.04M (+3.1%) vs. Q3 2022
Total value
$5.20B
−$1.46B (−21.9%) vs. Q3 2022
New holders
36
96 more added
Sold out
40
83 more reduced

2 institutions that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2022: 244 institutions
Q1 2021: 175 institutionsQ2 2021: 205 institutionsQ3 2021: 181 institutionsQ4 2021: 187 institutionsQ1 2022: 212 institutionsQ2 2022: 212 institutionsQ3 2022: 250 institutionsQ4 2022: 244 institutionsQ1 2023: 282 institutionsQ2 2023: 317 institutionsQ3 2023: 256 institutionsQ4 2023: 284 institutionsQ1 2024: 302 institutionsQ2 2024: 263 institutionsQ3 2024: 265 institutionsQ4 2024: 260 institutionsQ1 2025: 255 institutionsQ2 2025: 247 institutionsQ3 2025: 273 institutionsQ4 2025: 280 institutionsQ1 2026: 324 institutionsQ2 2026: 1 institution
Value heldQ4 2022: $5.20B
Q1 2021: $2.80BQ2 2021: $4.08BQ3 2021: $2.29BQ4 2021: $3.83BQ1 2022: $4.62BQ2 2022: $4.15BQ3 2022: $6.66BQ4 2022: $5.20BQ1 2023: $7.28BQ2 2023: $9.71BQ3 2023: $4.34BQ4 2023: $6.82BQ1 2024: $6.65BQ2 2024: $4.43BQ3 2024: $3.41BQ4 2024: $4.04BQ1 2025: $2.80BQ2 2025: $2.28BQ3 2025: $2.77BQ4 2025: $3.17BQ1 2026: $5.56BQ2 2026: $10.2K
Institutions holding APLS and their total value by quarter
QuarterHoldersValue
Q2 20261$10.2K
Q1 2026324$5.56B
Q4 2025280$3.17B
Q3 2025273$2.77B
Q2 2025247$2.28B
Q1 2025255$2.80B
Q4 2024260$4.04B
Q3 2024265$3.41B
Q2 2024263$4.43B
Q1 2024302$6.65B
Q4 2023284$6.82B
Q3 2023256$4.34B
Q2 2023317$9.71B
Q1 2023282$7.28B
Q4 2022244$5.20B
Q3 2022250$6.66B
Q2 2022212$4.15B
Q1 2022212$4.62B
Q4 2021187$3.83B
Q3 2021181$2.29B
Q2 2021205$4.08B
Q1 2021175$2.80B

Institutions, Q4 2022

Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q3 2022.

Institutions holding APLS in Q4 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Comerica Bank66,230$3.44M0.03%+66,230New
Tekla Capital Management LLC66,426$3.43M0.13%−199,650−75.0%Reduced
Brookfield Asset Management Inc.66,226$3.42M0.01%+5,996+10.0%Added
The PNC Financial Services Group, Inc.60,955$3.15M0.00%+3,009+5.2%Added
Nomura Holdings Inc59,465$3.07M0.03%+3,295+5.9%Added
Polar Asset Management Partners Inc.58,310$3.02M0.04%−324,290−84.8%Reduced
State of New Jersey Common Pension Fund D57,903$2.99M0.01%+3,069+5.6%Added
Ameriprise Financial Inc57,640$2.98M0.00%+1,099+1.9%Added
Lisanti Capital Growth, LLC55,695$2.88M0.39%−141,595−71.8%Reduced
Neuberger Berman Group LLC55,498$2.87M0.00%+11,164+25.2%Added
First Trust Advisors LP52,780$2.73M0.00%+27,551+109.2%Added
Group One Trading, L.P.50,823$2.63M0.09%+50,823New
MetLife Investment Management49,665$2.57M0.02%00.0%Unchanged
DekaBank Deutsche Girozentrale50,000$2.53M0.01%00.0%Unchanged
Guggenheim Capital LLC48,807$2.52M0.02%+13,288+37.4%Added
Mirae Asset Global Investments Co., Ltd.45,179$2.34M0.01%+2,291+5.3%Added
American International Group, Inc.44,361$2.29M0.02%−161−0.4%Reduced
Dimensional Fund Advisors LP41,007$2.12M0.00%−41,587−50.4%Reduced
Baird Financial Group, Inc.39,477$2.04M0.01%+7,533+23.6%Added
HighVista Strategies LLC39,111$2.02M1.20%−14,431−27.0%Reduced
Erste Asset Management GmbH37,000$1.91M0.04%00.0%Unchanged
BNP Paribas Arbitrage, SA36,196$1.87M0.00%−79,166−68.6%Reduced
Picton Mahoney Asset Management33,526$1.73M0.09%+2,676+8.7%Added
Algert Global LLC33,231$1.72M0.10%00.0%Unchanged
Parallax Volatility Advisers, L.P.31,880$1.65M0.04%−45,273−58.7%Reduced
Susquehanna International Group, LLP31,732$1.64M0.00%−26,128−45.2%Reduced
International Biotechnology Trust PLC31,700$1.64M0.51%+31,700New
SG Americas Securities, LLC31,382$1.62M0.02%+3,520+12.6%Added
Adage Capital Partners GP, L.L.C.31,000$1.60M0.00%+31,000New
Skandinaviska Enskilda Banken AB (publ)30,846$1.59M0.01%−6,208−16.8%Reduced
Clough Capital Partners L P28,609$1.48M0.15%−14,000−32.9%Reduced
State Board of Administration of Florida Retirement System28,116$1.45M0.00%+150+0.5%Added
Mutual of America Capital Management LLC28,089$1.45M0.02%+378+1.4%Added
Teacher Retirement System of Texas27,002$1.40M0.01%−860−3.1%Reduced
Axiom Investors LLC25,348$1.31M0.03%−6,627−20.7%Reduced
Mirabella Financial Services LLP25,326$1.31M0.12%+25,326New
EFG Asset Management (North America) Corp.25,377$1.31M0.29%−1,955−7.2%Reduced
Amundi25,838$1.29M0.00%−4,570−15.0%Reduced
Arizona State Retirement System24,801$1.28M0.01%+1,643+7.1%Added
ProShare Advisors LLC22,637$1.17M0.00%+1,569+7.4%Added
SG3 Management, LLC22,000$1.14M0.70%−18,000−45.0%Reduced
Regent Investment Management LLC21,309$1.10M0.30%00.0%Unchanged
Millennium Management LLC19,636$1.01M0.00%−238,233−92.4%Reduced
Knights of Columbus Asset Advisors LLC18,691$966.5K0.10%−367−1.9%Reduced
AQR Capital Management LLC17,191$888.9K0.00%+8,792+104.7%Added
Caption Management, LLC17,000$879.1K0.15%+17,000New
Wells Fargo & Company16,945$876.2K0.00%−2,653−13.5%Reduced
Schonfeld Strategic Advisors LLC16,400$848.0K0.01%−68,289−80.6%Reduced
Panagora Asset Management Inc16,231$839.3K0.01%−3,900−19.4%Reduced
Amalgamated Bank15,403$796.0K0.01%+231+1.5%Added
DuPont Capital Management Corp15,177$784.8K0.04%+8,833+139.2%Added
Virginia Retirement Systems Et Al15,000$775.6K0.01%−1,000−6.3%Reduced
ExodusPoint Capital Management, LP14,792$765.0K0.01%+14,792New
Raymond James & Associates14,437$746.5K0.00%+405+2.9%Added
Creative Planning14,087$728.4K0.00%+8,016+132.0%Added
Jane Street Group, LLC14,021$725.0K0.00%−2,977−17.5%Reduced
Capital Impact Advisors, LLC13,959$721.8K0.71%00.0%Unchanged
D. E. Shaw & Co., Inc.12,898$667.0K0.00%−184,466−93.5%Reduced
Capital Fund Management S.A.12,884$666.2K0.01%+12,884New
Profund Advisors LLC12,722$657.9K0.04%+315+2.5%Added
Hillsdale Investment Management Inc.12,600$651.5K0.06%00.0%Unchanged
Birchview Capital, LP12,000$621.0K0.44%00.0%Unchanged
Handelsbanken Fonder AB12,000$621.0K0.00%+300+2.6%Added
Duality Advisers, LP11,823$611.4K0.07%−26,234−68.9%Reduced
Crown Wealth Group, LLC11,814$610.9K0.57%+6,840+137.5%Added
Raymond James Financial Services Advisors, Inc.11,418$590.4K0.00%−262−2.2%Reduced
Stock Yards Bank & Trust Co11,215$580.0K0.02%+1,715+18.1%Added
SEI Investments Co10,796$558.3K0.00%−45,125−80.7%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)10,635$549.9K0.00%−880−7.6%Reduced
STRS Ohio10,400$537.0K0.00%−2,500−19.4%Reduced
Mackenzie Financial Corp10,302$532.7K0.00%−35,849−77.7%Reduced
Moore Capital Management, LP10,000$517.1K0.01%−169,958−94.4%Reduced
Cambridge Trust Co10,000$517.0K0.02%00.0%Unchanged
Nisa Investment Advisors, LLC9,848$509.0K0.00%−15−0.2%Reduced
Public Employees Retirement Association of Colorado9,749$504.0K0.00%00.0%Unchanged
Hennion & Walsh Asset Management, Inc.9,418$487.0K0.03%−48,299−83.7%Reduced
Harbour Capital Advisors, LLC9,487$477.0K0.16%+2,717+40.1%Added
Illinois Municipal Retirement Fund8,694$450.0K0.01%+8,694New
E Fund Management Co., Ltd.8,604$445.0K0.04%+1,554+22.0%Added
Keybank National Association8,373$433.0K0.00%00.0%Unchanged
Oppenheimer & Co Inc7,515$388.6K0.01%+132+1.8%Added
Pictet & Cie (Europe) SA7,262$375.5K0.02%−35−0.5%Reduced
Stifel Financial Corp7,210$372.8K0.00%+558+8.4%Added
Ameritas Investment Partners, Inc.7,353$372.1K0.01%00.0%Unchanged
Boulder Hill Capital Management LP7,100$367.1K0.30%+7,100New
Legato Capital Management LLC6,961$360.0K0.07%+6,961New
Polar Capital Holdings Plc6,900$356.8K0.00%00.0%Unchanged
Henshaw Capital LLC6,892$356.4K0.02%00.0%Unchanged
JustInvest LLC6,221$321.7K0.01%+6,221New
NJ State Employees Deferred Compensation Plan6,000$310.3K0.05%+6,000New
Metropolitan Life Insurance Co5,763$298.0K0.01%+131+2.3%Added
Virtus ETF Advisers LLC5,743$297.0K0.16%−313−5.2%Reduced
HC Advisors, LLC5,725$296.0K0.20%−35,640−86.2%Reduced
Stelac Advisory Services LLC5,520$285.4K0.13%+5,520New
Xponance, Inc.5,369$277.6K0.00%+114+2.2%Added
Citadel Advisors LLC5,269$272.5K0.00%−42,892−89.1%Reduced
Cowen and Company, LLC5,000$258.6K0.03%−14,000−73.7%Reduced
Cim Investment Mangement Inc4,581$236.9K0.09%+1,238+37.0%Added
Great West Life Assurance Co4,518$235.0K0.00%+430+10.5%Added
Compagnie Lombard Odier SCmA4,500$233.0K0.01%00.0%Unchanged