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Apellis Pharmaceuticals, Inc.

APLSDelisted May 14, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q4 2021

Institutional positions in Apellis Pharmaceuticals, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
187
+8 vs. Q3 2021
Shares held
81.0M
+11.5M (+16.6%) vs. Q3 2021
Total value
$3.83B
+$1.54B (+67.1%) vs. Q3 2021
New holders
44
73 more added
Sold out
36
53 more reduced

2 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 187 institutions
Q1 2021: 175 institutionsQ2 2021: 205 institutionsQ3 2021: 181 institutionsQ4 2021: 187 institutionsQ1 2022: 212 institutionsQ2 2022: 212 institutionsQ3 2022: 250 institutionsQ4 2022: 244 institutionsQ1 2023: 282 institutionsQ2 2023: 317 institutionsQ3 2023: 256 institutionsQ4 2023: 284 institutionsQ1 2024: 302 institutionsQ2 2024: 263 institutionsQ3 2024: 265 institutionsQ4 2024: 260 institutionsQ1 2025: 255 institutionsQ2 2025: 247 institutionsQ3 2025: 273 institutionsQ4 2025: 280 institutionsQ1 2026: 324 institutionsQ2 2026: 1 institution
Value heldQ4 2021: $3.83B
Q1 2021: $2.80BQ2 2021: $4.08BQ3 2021: $2.29BQ4 2021: $3.83BQ1 2022: $4.62BQ2 2022: $4.15BQ3 2022: $6.66BQ4 2022: $5.20BQ1 2023: $7.28BQ2 2023: $9.71BQ3 2023: $4.34BQ4 2023: $6.82BQ1 2024: $6.65BQ2 2024: $4.43BQ3 2024: $3.41BQ4 2024: $4.04BQ1 2025: $2.80BQ2 2025: $2.28BQ3 2025: $2.77BQ4 2025: $3.17BQ1 2026: $5.56BQ2 2026: $10.2K
Institutions holding APLS and their total value by quarter
QuarterHoldersValue
Q2 20261$10.2K
Q1 2026324$5.56B
Q4 2025280$3.17B
Q3 2025273$2.77B
Q2 2025247$2.28B
Q1 2025255$2.80B
Q4 2024260$4.04B
Q3 2024265$3.41B
Q2 2024263$4.43B
Q1 2024302$6.65B
Q4 2023284$6.82B
Q3 2023256$4.34B
Q2 2023317$9.71B
Q1 2023282$7.28B
Q4 2022244$5.20B
Q3 2022250$6.66B
Q2 2022212$4.15B
Q1 2022212$4.62B
Q4 2021187$3.83B
Q3 2021181$2.29B
Q2 2021205$4.08B
Q1 2021175$2.80B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q3 2021.

Institutions holding APLS in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
FinTrust Capital Advisors, LLC5$00.00%+5New
Covestor Ltd19$1.00K0.00%+19New
Lindbrook Capital, LLC38$2.00K0.00%00.0%Unchanged
Bell Investment Advisors, Inc61$3.00K0.00%+24+64.9%Added
Capital Analysts, LLC57$3.00K0.00%+57New
Smith Group Asset Management, LLC80$4.00K0.00%00.0%Unchanged
Parallel Advisors, LLC132$6.00K0.00%+73+123.7%Added
Itau Unibanco Holding S.A.163$8.00K0.00%+163New
Allworth Financial LP204$10.0K0.00%+204New
US Bancorp226$11.0K0.00%−117−34.1%Reduced
Rockefeller Capital Management L.P.272$12.0K0.00%+262+2,620.0%Added
Daiwa Securities Group Inc.298$14.0K0.00%00.0%Unchanged
CoreCap Advisors, LLC300$14.0K0.00%+300New
Captrust Financial Advisors326$15.0K0.00%−287−46.8%Reduced
TCI Wealth Advisors, Inc.308$15.0K0.00%+308New
Future Financial Wealth Managment LLC500$24.0K0.02%+500New
Point72 Hong Kong Ltd761$36.0K0.00%−8,218−91.5%Reduced
Harbor Investment Advisory, LLC1,267$60.0K0.01%+254+25.1%Added
Nisa Investment Advisors, LLC2,050$83.0K0.00%−2,902−58.6%Reduced
Eaton Vance Management2,025$96.0K0.00%+150+8.0%Added
Leonteq Securities AG2,223$105.1K0.00%00.0%Unchanged
Union Investments & Development Ltd.3,000$142.0K0.05%+3,000New
STRS Ohio3,100$146.0K0.00%−21,200−87.2%Reduced
Great West Life Assurance Co3,234$152.0K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.3,346$158.0K0.00%−655−16.4%Reduced
Amundi3,923$160.0K0.00%00.0%Unchanged
IMA Wealth, Inc.4,000$189.0K0.04%00.0%Unchanged
S.A. Mason LLC4,155$196.0K0.12%00.0%Unchanged
HSBC Holdings PLC4,601$219.0K0.00%+4,601New
Crown Wealth Group, LLC5,040$238.0K0.22%+5,040New
Cutler Group LP5,293$250.0K0.02%−96,492−94.8%Reduced
LSP Investment Advisors, LLC5,500$260.0K0.11%+5,500New
Ameritas Investment Partners, Inc.5,580$264.0K0.01%+550+10.9%Added
Virginia Retirement Systems Et Al5,600$265.0K0.00%+5,600New
Creative Planning5,931$280.0K0.00%+5,931New
Pictet & Cie (Europe) SA6,335$300.0K0.01%+6,335New
Henshaw Capital LLC6,519$308.2K0.02%+6,519New
Allstate Corp6,694$316.0K0.01%+6,694New
Raymond James & Associates6,840$323.0K0.00%−416−5.7%Reduced
Algert Global LLC7,367$348.0K0.04%+7,367New
MML Investors Services, LLC7,891$373.0K0.00%−79−1.0%Reduced
AlphaCrest Capital Management LLC8,556$405.0K0.02%+8,556New
Stonnington Group, LLC10,000$412.0K0.09%+10,000New
Virtus ETF Advisers LLC8,725$413.0K0.16%+1,673+23.7%Added
Compagnie Lombard Odier SCmA9,000$426.0K0.01%00.0%Unchanged
Connor, Clark & Lunn Investment Management Ltd.9,406$445.0K0.00%−68,089−87.9%Reduced
Public Employees Retirement Association of Colorado9,749$461.0K0.00%00.0%Unchanged
Dimensional Fund Advisors LP9,828$465.0K0.00%−574−5.5%Reduced
Cornerstone National Bank & Trust Co10,000$472.8K0.21%00.0%Unchanged
Cambridge Trust Co10,000$473.0K0.02%+10,000New
Parallax Volatility Advisers, L.P.10,936$517.0K0.01%+10,892+24,754.5%Added
Tower Research Capital LLC (TRC)11,416$539.0K0.01%−4,728−29.3%Reduced
Birchview Capital, LP12,000$567.0K0.37%00.0%Unchanged
HC Advisors, LLC12,060$570.0K0.35%+12,060New
Amalgamated Bank12,551$593.0K0.00%+997+8.6%Added
Magnetar Financial LLC12,541$593.0K0.01%+12,541New
Jacob Asset Management of New York LLC12,855$608.0K0.27%−3,233−20.1%Reduced
The PNC Financial Services Group, Inc.12,948$612.0K0.00%+6,890+113.7%Added
Handelsbanken Fonder AB13,400$634.0K0.00%00.0%Unchanged
Nomura Holdings Inc13,491$640.0K0.00%−271,009−95.3%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)13,669$646.0K0.00%+6,353+86.8%Added
ExodusPoint Capital Management, LP13,939$659.0K0.01%+13,939New
Teacher Retirement System of Texas14,636$692.0K0.00%+5,085+53.2%Added
BNP Paribas Arbitrage, SA14,937$706.2K0.00%+3,497+30.6%Added
Janus Henderson Group PLC15,907$753.0K0.00%+9,814+161.1%Added
Knights of Columbus Asset Advisors LLC16,473$779.0K0.06%+245+1.5%Added
Metropolitan Life Insurance Co18,406$870.2K0.01%+749+4.2%Added
Arizona State Retirement System20,617$975.0K0.01%+4,172+25.4%Added
Regent Investment Management LLC21,309$1.01M0.22%00.0%Unchanged
Principal Financial Group Inc22,608$1.07M0.00%−7,301−24.4%Reduced
MetLife Investment Management24,726$1.17M0.01%+527+2.2%Added
Raymond James Financial Services Advisors, Inc.26,074$1.23M0.00%+9,938+61.6%Added
Cubist Systematic Strategies, LLC26,297$1.24M0.01%−7,549−22.3%Reduced
Allspring Global Investments Holdings, LLC26,768$1.26M0.00%+26,768New
State Board of Administration of Florida Retirement System26,796$1.27M0.00%00.0%Unchanged
Cinctive Capital Management LP27,552$1.30M0.06%−23,448−46.0%Reduced
ProShare Advisors LLC29,151$1.38M0.00%+2,257+8.4%Added
Allianz Asset Management GmbH29,350$1.39M0.00%+29,350New
Two Sigma Advisers, LP30,600$1.45M0.00%−461,000−93.8%Reduced
HRT Financial LP32,355$1.53M0.01%+32,355New
International Biotechnology Trust PLC32,500$1.54M0.34%+32,500New
Group One Trading, L.P.36,021$1.70M0.03%−69,731−65.9%Reduced
Manufacturers Life Insurance Company, The35,949$1.72M0.00%+1,925+5.7%Added
Erste Asset Management GmbH37,000$1.75M0.03%+20,000+117.6%Added
Tygh Capital Management, Inc.37,542$1.77M0.23%−75−0.2%Reduced
D. E. Shaw & Co., Inc.37,890$1.79M0.00%−37,632−49.8%Reduced
American International Group, Inc.37,988$1.80M0.01%+2,439+6.9%Added
Toronto Dominion Bank38,421$1.82M0.00%+38,421New
Woodline Partners LP41,199$1.95M0.03%−66,877−61.9%Reduced
DekaBank Deutsche Girozentrale43,400$2.04M0.00%+18,700+75.7%Added
Parametric Portfolio Associates LLC43,733$2.07M0.00%−6,157−12.3%Reduced
Aufman Associates Inc46,751$2.21M1.63%−6,891−12.8%Reduced
J. Goldman & Co LP48,013$2.27M0.21%+48,013New
Guggenheim Capital LLC48,251$2.28M0.01%+4,607+10.6%Added
Invesco Ltd.48,549$2.29M0.00%−6,189−11.3%Reduced
Baird Financial Group, Inc.53,075$2.51M0.01%+22,377+72.9%Added
Castleark Management LLC53,130$2.51M0.09%+53,130New
EFG Asset Management (North America) Corp.57,055$2.70M0.35%+57,055New
Credit Suisse AG63,032$2.98M0.00%+3,845+6.5%Added
Wells Fargo & Company63,925$3.02M0.00%+13,336+26.4%Added