Apellis Pharmaceuticals, Inc.
APLSDelisted May 14, 2026- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001492422
Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.
13F holders, Q4 2021
Institutional positions in Apellis Pharmaceuticals, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 187
- +8 vs. Q3 2021
- Shares held
- 81.0M
- +11.5M (+16.6%) vs. Q3 2021
- Total value
- $3.83B
- +$1.54B (+67.1%) vs. Q3 2021
- New holders
- 44
- 73 more added
- Sold out
- 36
- 53 more reduced
2 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1 | $10.2K |
| Q1 2026 | 324 | $5.56B |
| Q4 2025 | 280 | $3.17B |
| Q3 2025 | 273 | $2.77B |
| Q2 2025 | 247 | $2.28B |
| Q1 2025 | 255 | $2.80B |
| Q4 2024 | 260 | $4.04B |
| Q3 2024 | 265 | $3.41B |
| Q2 2024 | 263 | $4.43B |
| Q1 2024 | 302 | $6.65B |
| Q4 2023 | 284 | $6.82B |
| Q3 2023 | 256 | $4.34B |
| Q2 2023 | 317 | $9.71B |
| Q1 2023 | 282 | $7.28B |
| Q4 2022 | 244 | $5.20B |
| Q3 2022 | 250 | $6.66B |
| Q2 2022 | 212 | $4.15B |
| Q1 2022 | 212 | $4.62B |
| Q4 2021 | 187 | $3.83B |
| Q3 2021 | 181 | $2.29B |
| Q2 2021 | 205 | $4.08B |
| Q1 2021 | 175 | $2.80B |
Institutions, Q4 2021
Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q3 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| American International Group, Inc. | 37,988 | $1.80M | 0.01% | +2,439+6.9% | Added |
| D. E. Shaw & Co., Inc. | 37,890 | $1.79M | 0.00% | −37,632−49.8% | Reduced |
| Tygh Capital Management, Inc. | 37,542 | $1.77M | 0.23% | −75−0.2% | Reduced |
| Erste Asset Management GmbH | 37,000 | $1.75M | 0.03% | +20,000+117.6% | Added |
| Manufacturers Life Insurance Company, The | 35,949 | $1.72M | 0.00% | +1,925+5.7% | Added |
| Group One Trading, L.P. | 36,021 | $1.70M | 0.03% | −69,731−65.9% | Reduced |
| International Biotechnology Trust PLC | 32,500 | $1.54M | 0.34% | +32,500 | New |
| HRT Financial LP | 32,355 | $1.53M | 0.01% | +32,355 | New |
| Two Sigma Advisers, LP | 30,600 | $1.45M | 0.00% | −461,000−93.8% | Reduced |
| Allianz Asset Management GmbH | 29,350 | $1.39M | 0.00% | +29,350 | New |
| ProShare Advisors LLC | 29,151 | $1.38M | 0.00% | +2,257+8.4% | Added |
| Cinctive Capital Management LP | 27,552 | $1.30M | 0.06% | −23,448−46.0% | Reduced |
| State Board of Administration of Florida Retirement System | 26,796 | $1.27M | 0.00% | 00.0% | Unchanged |
| Allspring Global Investments Holdings, LLC | 26,768 | $1.26M | 0.00% | +26,768 | New |
| Cubist Systematic Strategies, LLC | 26,297 | $1.24M | 0.01% | −7,549−22.3% | Reduced |
| Raymond James Financial Services Advisors, Inc. | 26,074 | $1.23M | 0.00% | +9,938+61.6% | Added |
| MetLife Investment Management | 24,726 | $1.17M | 0.01% | +527+2.2% | Added |
| Principal Financial Group Inc | 22,608 | $1.07M | 0.00% | −7,301−24.4% | Reduced |
| Regent Investment Management LLC | 21,309 | $1.01M | 0.22% | 00.0% | Unchanged |
| Arizona State Retirement System | 20,617 | $975.0K | 0.01% | +4,172+25.4% | Added |
| Metropolitan Life Insurance Co | 18,406 | $870.2K | 0.01% | +749+4.2% | Added |
| Knights of Columbus Asset Advisors LLC | 16,473 | $779.0K | 0.06% | +245+1.5% | Added |
| Janus Henderson Group PLC | 15,907 | $753.0K | 0.00% | +9,814+161.1% | Added |
| BNP Paribas Arbitrage, SA | 14,937 | $706.2K | 0.00% | +3,497+30.6% | Added |
| Teacher Retirement System of Texas | 14,636 | $692.0K | 0.00% | +5,085+53.2% | Added |
| ExodusPoint Capital Management, LP | 13,939 | $659.0K | 0.01% | +13,939 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 13,669 | $646.0K | 0.00% | +6,353+86.8% | Added |
| Nomura Holdings Inc | 13,491 | $640.0K | 0.00% | −271,009−95.3% | Reduced |
| Handelsbanken Fonder AB | 13,400 | $634.0K | 0.00% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 12,948 | $612.0K | 0.00% | +6,890+113.7% | Added |
| Jacob Asset Management of New York LLC | 12,855 | $608.0K | 0.27% | −3,233−20.1% | Reduced |
| Amalgamated Bank | 12,551 | $593.0K | 0.00% | +997+8.6% | Added |
| Magnetar Financial LLC | 12,541 | $593.0K | 0.01% | +12,541 | New |
| HC Advisors, LLC | 12,060 | $570.0K | 0.35% | +12,060 | New |
| Birchview Capital, LP | 12,000 | $567.0K | 0.37% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 11,416 | $539.0K | 0.01% | −4,728−29.3% | Reduced |
| Parallax Volatility Advisers, L.P. | 10,936 | $517.0K | 0.01% | +10,892+24,754.5% | Added |
| Cambridge Trust Co | 10,000 | $473.0K | 0.02% | +10,000 | New |
| Cornerstone National Bank & Trust Co | 10,000 | $472.8K | 0.21% | 00.0% | Unchanged |
| Dimensional Fund Advisors LP | 9,828 | $465.0K | 0.00% | −574−5.5% | Reduced |
| Public Employees Retirement Association of Colorado | 9,749 | $461.0K | 0.00% | 00.0% | Unchanged |
| Connor, Clark & Lunn Investment Management Ltd. | 9,406 | $445.0K | 0.00% | −68,089−87.9% | Reduced |
| Compagnie Lombard Odier SCmA | 9,000 | $426.0K | 0.01% | 00.0% | Unchanged |
| Virtus ETF Advisers LLC | 8,725 | $413.0K | 0.16% | +1,673+23.7% | Added |
| Stonnington Group, LLC | 10,000 | $412.0K | 0.09% | +10,000 | New |
| AlphaCrest Capital Management LLC | 8,556 | $405.0K | 0.02% | +8,556 | New |
| MML Investors Services, LLC | 7,891 | $373.0K | 0.00% | −79−1.0% | Reduced |
| Algert Global LLC | 7,367 | $348.0K | 0.04% | +7,367 | New |
| Raymond James & Associates | 6,840 | $323.0K | 0.00% | −416−5.7% | Reduced |
| Allstate Corp | 6,694 | $316.0K | 0.01% | +6,694 | New |
| Henshaw Capital LLC | 6,519 | $308.2K | 0.02% | +6,519 | New |
| Pictet & Cie (Europe) SA | 6,335 | $300.0K | 0.01% | +6,335 | New |
| Creative Planning | 5,931 | $280.0K | 0.00% | +5,931 | New |
| Virginia Retirement Systems Et Al | 5,600 | $265.0K | 0.00% | +5,600 | New |
| Ameritas Investment Partners, Inc. | 5,580 | $264.0K | 0.01% | +550+10.9% | Added |
| LSP Investment Advisors, LLC | 5,500 | $260.0K | 0.11% | +5,500 | New |
| Cutler Group LP | 5,293 | $250.0K | 0.02% | −96,492−94.8% | Reduced |
| Crown Wealth Group, LLC | 5,040 | $238.0K | 0.22% | +5,040 | New |
| HSBC Holdings PLC | 4,601 | $219.0K | 0.00% | +4,601 | New |
| S.A. Mason LLC | 4,155 | $196.0K | 0.12% | 00.0% | Unchanged |
| IMA Wealth, Inc. | 4,000 | $189.0K | 0.04% | 00.0% | Unchanged |
| Amundi | 3,923 | $160.0K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 3,346 | $158.0K | 0.00% | −655−16.4% | Reduced |
| Great West Life Assurance Co | 3,234 | $152.0K | 0.00% | 00.0% | Unchanged |
| STRS Ohio | 3,100 | $146.0K | 0.00% | −21,200−87.2% | Reduced |
| Union Investments & Development Ltd. | 3,000 | $142.0K | 0.05% | +3,000 | New |
| Leonteq Securities AG | 2,223 | $105.1K | 0.00% | 00.0% | Unchanged |
| Eaton Vance Management | 2,025 | $96.0K | 0.00% | +150+8.0% | Added |
| Nisa Investment Advisors, LLC | 2,050 | $83.0K | 0.00% | −2,902−58.6% | Reduced |
| Harbor Investment Advisory, LLC | 1,267 | $60.0K | 0.01% | +254+25.1% | Added |
| Point72 Hong Kong Ltd | 761 | $36.0K | 0.00% | −8,218−91.5% | Reduced |
| Future Financial Wealth Managment LLC | 500 | $24.0K | 0.02% | +500 | New |
| Captrust Financial Advisors | 326 | $15.0K | 0.00% | −287−46.8% | Reduced |
| TCI Wealth Advisors, Inc. | 308 | $15.0K | 0.00% | +308 | New |
| Daiwa Securities Group Inc. | 298 | $14.0K | 0.00% | 00.0% | Unchanged |
| CoreCap Advisors, LLC | 300 | $14.0K | 0.00% | +300 | New |
| Rockefeller Capital Management L.P. | 272 | $12.0K | 0.00% | +262+2,620.0% | Added |
| US Bancorp | 226 | $11.0K | 0.00% | −117−34.1% | Reduced |
| Allworth Financial LP | 204 | $10.0K | 0.00% | +204 | New |
| Itau Unibanco Holding S.A. | 163 | $8.00K | 0.00% | +163 | New |
| Parallel Advisors, LLC | 132 | $6.00K | 0.00% | +73+123.7% | Added |
| Smith Group Asset Management, LLC | 80 | $4.00K | 0.00% | 00.0% | Unchanged |
| Bell Investment Advisors, Inc | 61 | $3.00K | 0.00% | +24+64.9% | Added |
| Capital Analysts, LLC | 57 | $3.00K | 0.00% | +57 | New |
| Lindbrook Capital, LLC | 38 | $2.00K | 0.00% | 00.0% | Unchanged |
| Covestor Ltd | 19 | $1.00K | 0.00% | +19 | New |
| FinTrust Capital Advisors, LLC | 5 | $0 | 0.00% | +5 | New |
| AJU IB Investment Co., Ltd. | 0 | $0 | 0.00% | −624,962−100.0% | Sold out |
| Franklin Resources Inc | 0 | $0 | 0.00% | −610,339−100.0% | Sold out |
| Arrowstreet Capital, Limited Partnership | 0 | $0 | 0.00% | −418,539−100.0% | Sold out |
| Two Sigma Investments, LP | 0 | $0 | 0.00% | −362,204−100.0% | Sold out |
| Ikarian Capital, LLC | 0 | $0 | 0.00% | −347,545−100.0% | Sold out |
| Natixis | 0 | $0 | 0.00% | −216,500−100.0% | Sold out |
| Jefferies Group LLC | 0 | $0 | 0.00% | −165,038−100.0% | Sold out |
| Tudor Investment Corp Et Al | 0 | $0 | 0.00% | −150,703−100.0% | Sold out |
| LMR Partners LLP | 0 | $0 | 0.00% | −121,111−100.0% | Sold out |
| Duality Advisers, LP | 0 | $0 | 0.00% | −111,100−100.0% | Sold out |
| Alps Advisors Inc | 0 | $0 | 0.00% | −106,632−100.0% | Sold out |
| Kingdon Capital Management, L.L.C. | 0 | $0 | 0.00% | −100,000−100.0% | Sold out |
| SG3 Management, LLC | 0 | $0 | 0.00% | −100,000−100.0% | Sold out |