Apellis Pharmaceuticals, Inc.
APLS已下市- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0001492422
Apellis Pharmaceuticals, Inc. 已在 2026 年下市；內部人最後一份 Form 4 在 2026/5/14 申報；2026 年第 1 季末有 324 家機構在 13F 申報持有，市值合計 $55.6 億；大師中只有索羅斯基金管理持有。
2025 年第 2 季 13F 持有人
Apellis Pharmaceuticals, Inc. 在 2025/6/30 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 247
- 較 2025 年第 1 季 −6 家
- 持有股數
- 1.32 億
- 較 2025 年第 1 季 +353.8 萬 (+2.8%)
- 總市值
- $22.8 億
- 較 2025 年第 1 季 −$5.24 億 (−18.7%)
- 新進機構
- 43
- 另有 108 家加碼
- 清倉機構
- 49
- 另有 68 家減碼
另有 2 家機構在 2025 年第 1 季持有、還沒有申報 2025 年第 2 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 APLS 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 1 | $1.02 萬 |
| 2026 年第 1 季 | 324 | $55.6 億 |
| 2025 年第 4 季 | 280 | $31.7 億 |
| 2025 年第 3 季 | 273 | $27.7 億 |
| 2025 年第 2 季 | 247 | $22.9 億 |
| 2025 年第 1 季 | 255 | $28.0 億 |
| 2024 年第 4 季 | 260 | $40.5 億 |
| 2024 年第 3 季 | 265 | $35.2 億 |
| 2024 年第 2 季 | 263 | $45.6 億 |
| 2024 年第 1 季 | 302 | $69.7 億 |
| 2023 年第 4 季 | 284 | $71.6 億 |
| 2023 年第 3 季 | 256 | $43.4 億 |
| 2023 年第 2 季 | 317 | $98.1 億 |
| 2023 年第 1 季 | 282 | $74.9 億 |
| 2022 年第 4 季 | 244 | $52.6 億 |
| 2022 年第 3 季 | 250 | $66.7 億 |
| 2022 年第 2 季 | 212 | $41.5 億 |
| 2022 年第 1 季 | 212 | $46.2 億 |
| 2021 年第 4 季 | 187 | $39.1 億 |
| 2021 年第 3 季 | 181 | $22.9 億 |
| 2021 年第 2 季 | 205 | $41.3 億 |
| 2021 年第 1 季 | 175 | $28.0 億 |
2025 年第 2 季持有機構
每家機構持有 Apellis Pharmaceuticals, Inc. 的股數、市值與佔組合比重；股數變化跟 2025 年第 1 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Avoro Capital Advisors LLC | 12,222,222 | $2.12 億 | 3.71% | 00.0% | 不變 |
| EcoR1 Capital, LLC | 11,895,808 | $2.06 億 | 12.20% | 00.0% | 不變 |
| Vanguard Group Inc | 10,154,751 | $1.76 億 | 0.00% | +24,395+0.2% | 加碼 |
| Morgan Stanley | 9,752,201 | $1.69 億 | 0.01% | +126,078+1.3% | 加碼 |
| Wellington Management Group LLP | 8,976,962 | $1.55 億 | 0.03% | −3,326,290−27.0% | 減碼 |
| Deep Track Capital, LP | 7,000,000 | $1.21 億 | 3.90% | +2,000,000+40.0% | 加碼 |
| BlackRock, Inc. | 6,404,999 | $1.11 億 | 0.00% | +75,401+1.2% | 加碼 |
| AQR Capital Management LLC | 5,976,414 | $1.03 億 | 0.09% | +1,898,995+46.6% | 加碼 |
| UBS Group AG | 4,735,311 | $8,197 萬 | 0.02% | +1,463,117+44.7% | 加碼 |
| State Street Corp | 3,562,721 | $6,167 萬 | 0.00% | −378,684−9.6% | 減碼 |
| Suvretta Capital Management, LLC | 2,878,000 | $4,982 萬 | 1.88% | +1,231,385+74.8% | 加碼 |
| Marshall Wace, LLP | 2,704,837 | $4,682 萬 | 0.06% | +2,681,263+11,373.8% | 加碼 |
| Jennison Associates LLC | 2,661,823 | $4,608 萬 | 0.03% | +184,292+7.4% | 加碼 |
| Siren, L.L.C. | 2,578,396 | $4,463 萬 | 2.31% | 00.0% | 不變 |
| Bank of America Corp | 2,426,628 | $4,200 萬 | 0.00% | −704,808−22.5% | 減碼 |
| Norges Bank | 2,367,224 | $4,098 萬 | 0.01% | +793,623+50.4% | 加碼 |
| Geode Capital Management, LLC | 1,995,271 | $3,454 萬 | 0.00% | +45,225+2.3% | 加碼 |
| Amundi | 1,604,105 | $2,859 萬 | 0.01% | +1,274,523+386.7% | 加碼 |
| Deutsche Bank AG | 1,496,296 | $2,590 萬 | 0.01% | −280,280−15.8% | 減碼 |
| OrbiMed Advisors LLC | 1,482,300 | $2,566 萬 | 0.65% | +50,000+3.5% | 加碼 |
| Polar Capital Holdings Plc | 1,352,175 | $2,341 萬 | 0.12% | −225,000−14.3% | 減碼 |
| BNP Paribas Arbitrage, SA | 1,298,459 | $2,248 萬 | 0.02% | +187,750+16.9% | 加碼 |
| Braidwell LP | 1,121,034 | $1,941 萬 | 0.66% | −531,300−32.2% | 減碼 |
| Wells Fargo & Company | 1,043,655 | $1,807 萬 | 0.00% | +1,039,031+22,470.4% | 加碼 |
| Charles Schwab Investment Management Inc | 989,143 | $1,712 萬 | 0.00% | +24,644+2.6% | 加碼 |
| Octagon Capital Advisors LP | 903,500 | $1,564 萬 | 3.43% | −1,190,500−56.9% | 減碼 |
| Camber Capital Management LP | 850,000 | $1,471 萬 | 2.05% | +850,000 | 新進 |
| Royal Bank of Canada | 797,585 | $1,381 萬 | 0.00% | +2,650+0.3% | 加碼 |
| Ameriprise Financial Inc | 750,161 | $1,299 萬 | 0.00% | +283,500+60.8% | 加碼 |
| Bank of Nova Scotia | 594,812 | $1,030 萬 | 0.02% | +594,812 | 新進 |
| Jefferies Financial Group Inc. | 578,205 | $1,001 萬 | 0.17% | −21,050−3.5% | 減碼 |
| Jump Financial, LLC | 558,668 | $967.1 萬 | 0.12% | +293,075+110.3% | 加碼 |
| Ossiam | 555,953 | $962.4 萬 | 0.11% | +555,953 | 新進 |
| Capitolis Liquid Global Markets LLC | 544,600 | $942.7 萬 | 0.07% | +544,600 | 新進 |
| Woodline Partners LP | 530,923 | $919.0 萬 | 0.05% | +312,073+142.6% | 加碼 |
| Northern Trust Corp | 525,882 | $910.3 萬 | 0.00% | +7,188+1.4% | 加碼 |
| Schroder Investment Management Group | 485,615 | $840.6 萬 | 0.01% | +232,506+91.9% | 加碼 |
| Hudson Bay Capital Management LP | 475,000 | $822.2 萬 | 0.05% | +164,300+52.9% | 加碼 |
| Nuveen, LLC | 469,253 | $812.3 萬 | 0.00% | −22,985−4.7% | 減碼 |
| Voloridge Investment Management, LLC | 468,710 | $811.3 萬 | 0.03% | +214,920+84.7% | 加碼 |
| Citadel Advisors LLC | 442,560 | $766.1 萬 | 0.01% | +218,464+97.5% | 加碼 |
| 683 Capital Management, LLC | 410,000 | $709.7 萬 | 0.72% | +77,000+23.1% | 加碼 |
| Two Sigma Investments, LP | 406,913 | $704.4 萬 | 0.01% | +144,009+54.8% | 加碼 |
| Pictet Asset Management Holding SA | 348,349 | $607.1 萬 | 0.01% | +33,507+10.6% | 加碼 |
| Ieq Capital, LLC | 346,923 | $600.5 萬 | 0.04% | +55,065+18.9% | 加碼 |
| Canada Pension Plan Investment Board | 336,800 | $583.0 萬 | 0.00% | −711,900−67.9% | 減碼 |
| Squarepoint Ops LLC | 329,392 | $570.2 萬 | 0.01% | −113,401−25.6% | 減碼 |
| Susquehanna International Group, LLP | 328,726 | $569.0 萬 | 0.01% | +299,221+1,014.1% | 加碼 |
| Trexquant Investment LP | 327,421 | $566.8 萬 | 0.06% | −57,501−14.9% | 減碼 |
| ING Groep NV | 308,300 | $533.7 萬 | 0.03% | +124,100+67.4% | 加碼 |
| UBS Asset Management Americas Inc | 301,939 | $522.7 萬 | 0.00% | +79,305+35.6% | 加碼 |
| Barclays PLC | 273,912 | $474.1 萬 | 0.00% | +82,675+43.2% | 加碼 |
| Two Sigma Advisers, LP | 256,800 | $444.5 萬 | 0.01% | +65,000+33.9% | 加碼 |
| D. E. Shaw & Co., Inc. | 251,069 | $434.6 萬 | 0.00% | +251,069 | 新進 |
| Jane Street Group, LLC | 246,199 | $426.2 萬 | 0.01% | −9,893−3.9% | 減碼 |
| Bank of New York Mellon Corp | 243,327 | $421.2 萬 | 0.00% | −85,846−26.1% | 減碼 |
| JPMorgan Chase & Co | 234,801 | $406.4 萬 | 0.00% | −188,999−44.6% | 減碼 |
| Caption Management, LLC | 230,888 | $399.7 萬 | 0.37% | +218,888+1,824.1% | 加碼 |
| Edgestream Partners, L.P. | 218,392 | $378.0 萬 | 0.11% | −22,895−9.5% | 減碼 |
| Goldman Sachs Group Inc | 215,999 | $373.9 萬 | 0.00% | −91,710−29.8% | 減碼 |
| Fiduciary Trust Co | 202,536 | $350.6 萬 | 0.04% | −800−0.4% | 減碼 |
| Millennium Management LLC | 202,452 | $350.4 萬 | 0.00% | −249,521−55.2% | 減碼 |
| Aquatic Capital Management LLC | 176,704 | $305.9 萬 | 0.06% | −39,172−18.1% | 減碼 |
| Invesco Ltd. | 166,135 | $287.6 萬 | 0.00% | −475,262−74.1% | 減碼 |
| Y-Intercept (Hong Kong) Ltd | 164,275 | $284.4 萬 | 0.07% | +134,698+455.4% | 加碼 |
| PDT Partners, LLC | 160,058 | $277.1 萬 | 0.16% | −35,107−18.0% | 減碼 |
| Bank of Montreal | 159,613 | $276.3 萬 | 0.00% | +1,040+0.7% | 加碼 |
| Algert Global LLC | 154,113 | $266.8 萬 | 0.06% | −184,500−54.5% | 減碼 |
| Prudential Financial Inc | 154,010 | $266.6 萬 | 0.00% | −63,870−29.3% | 減碼 |
| Voya Investment Management LLC | 150,593 | $260.7 萬 | 0.00% | +25,192+20.1% | 加碼 |
| Rafferty Asset Management, LLC | 143,852 | $249.0 萬 | 0.01% | −36,282−20.1% | 減碼 |
| Swiss National Bank | 143,800 | $248.9 萬 | 0.00% | +11,200+8.4% | 加碼 |
| Steward Partners Investment Advisory, LLC | 140,975 | $244.0 萬 | 0.02% | +18,800+15.4% | 加碼 |
| Citigroup Inc | 138,451 | $239.7 萬 | 0.00% | −278,168−66.8% | 減碼 |
| California Public Employees Retirement System | 134,637 | $233.1 萬 | 0.00% | +7,931+6.3% | 加碼 |
| CWM, LLC | 127,584 | $220.8 萬 | 0.01% | +29,326+29.8% | 加碼 |
| Rhumbline Advisers | 122,002 | $211.2 萬 | 0.00% | −2,452−2.0% | 減碼 |
| Gotham Asset Management, LLC | 119,229 | $206.4 萬 | 0.01% | +84,944+247.8% | 加碼 |
| Connor, Clark & Lunn Investment Management Ltd. | 118,724 | $205.5 萬 | 0.01% | −13,171−10.0% | 減碼 |
| J. Safra Sarasin Holding AG | 115,684 | $200.2 萬 | 0.03% | +68,588+145.6% | 加碼 |
| Cerity Partners LLC | 114,745 | $198.6 萬 | 0.00% | +60,301+110.8% | 加碼 |
| Sphera Funds Management Ltd. | 114,346 | $197.9 萬 | 0.52% | −67,000−36.9% | 減碼 |
| HRT Financial LP | 107,200 | $185.5 萬 | 0.01% | +107,200 | 新進 |
| Wealth Enhancement Advisory Services, LLC | 100,666 | $183.8 萬 | 0.00% | +30,507+43.5% | 加碼 |
| EFG Asset Management (North America) Corp. | 105,024 | $181.7 萬 | 0.26% | +65,661+166.8% | 加碼 |
| Dark Forest Capital Management LP | 104,725 | $181.3 萬 | 0.07% | +104,725 | 新進 |
| Exome Asset Management LLC | 98,600 | $170.7 萬 | 1.41% | +98,600 | 新進 |
| Legal & General Group Plc | 96,050 | $166.3 萬 | 0.00% | +16,980+21.5% | 加碼 |
| Verition Fund Management LLC | 95,605 | $165.5 萬 | 0.01% | −14,905−13.5% | 減碼 |
| State of Wisconsin Investment Board | 94,404 | $163.4 萬 | 0.00% | +9,789+11.6% | 加碼 |
| J. Goldman & Co LP | 93,574 | $162.0 萬 | 0.05% | +93,574 | 新進 |
| Rhenman & Partners Asset Management AB | 93,250 | $161.4 萬 | 0.20% | +65,000+230.1% | 加碼 |
| Price T Rowe Associates Inc | 92,151 | $159.6 萬 | 0.00% | +1,451+1.6% | 加碼 |
| State Board of Administration of Florida Retirement System | 91,408 | $158.2 萬 | 0.00% | −410−0.4% | 減碼 |
| Natixis | 90,666 | $156.9 萬 | 0.01% | −564,361−86.2% | 減碼 |
| California State Teachers Retirement System | 87,929 | $152.2 萬 | 0.00% | +28,151+47.1% | 加碼 |
| HighVista Strategies LLC | 86,663 | $150.0 萬 | 0.55% | −22,051−20.3% | 減碼 |
| Rock Springs Capital Management LP | 84,300 | $145.9 萬 | 0.09% | +4,300+5.4% | 加碼 |
| Schonfeld Strategic Advisors LLC | 83,916 | $145.3 萬 | 0.01% | −97,484−53.7% | 減碼 |
| Walleye Capital LLC | 81,270 | $140.7 萬 | 0.01% | −236,172−74.4% | 減碼 |