Apellis Pharmaceuticals, Inc.
APLSDelisted May 14, 2026- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001492422
Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.
13F holders, Q3 2025
Institutional positions in Apellis Pharmaceuticals, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 273
- +31 vs. Q2 2025
- Shares held
- 122.3M
- −5.96M (−4.6%) vs. Q2 2025
- Total value
- $2.77B
- +$549.5M (+24.7%) vs. Q2 2025
- New holders
- 61
- 92 more added
- Sold out
- 30
- 91 more reduced
5 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1 | $10.2K |
| Q1 2026 | 324 | $5.56B |
| Q4 2025 | 280 | $3.17B |
| Q3 2025 | 273 | $2.77B |
| Q2 2025 | 247 | $2.28B |
| Q1 2025 | 255 | $2.80B |
| Q4 2024 | 260 | $4.04B |
| Q3 2024 | 265 | $3.41B |
| Q2 2024 | 263 | $4.43B |
| Q1 2024 | 302 | $6.65B |
| Q4 2023 | 284 | $6.82B |
| Q3 2023 | 256 | $4.34B |
| Q2 2023 | 317 | $9.71B |
| Q1 2023 | 282 | $7.28B |
| Q4 2022 | 244 | $5.20B |
| Q3 2022 | 250 | $6.66B |
| Q2 2022 | 212 | $4.15B |
| Q1 2022 | 212 | $4.62B |
| Q4 2021 | 187 | $3.83B |
| Q3 2021 | 181 | $2.29B |
| Q2 2021 | 205 | $4.08B |
| Q1 2021 | 175 | $2.80B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Bleakley Financial Group, LLC | 79,305 | $1.79M | 0.04% | +2,217+2.9% | Added |
| Raymond James Financial Inc | 77,678 | $1.76M | 0.00% | +3,212+4.3% | Added |
| Mackenzie Financial Corp | 76,711 | $1.74M | 0.00% | +2,546+3.4% | Added |
| Landscape Capital Management, L.L.C. | 75,000 | $1.70M | 0.11% | +10,479+16.2% | Added |
| California State Teachers Retirement System | 73,298 | $1.66M | 0.00% | −14,631−16.6% | Reduced |
| J. Safra Sarasin Holding AG | 70,500 | $1.60M | 0.03% | −45,184−39.1% | Reduced |
| Man Group plc | 67,202 | $1.52M | 0.00% | +67,202 | New |
| Engineers Gate Manager LP | 66,336 | $1.50M | 0.02% | +7,618+13.0% | Added |
| Macquarie Group Ltd | 65,156 | $1.47M | 0.00% | +65,156 | New |
| Sphera Funds Management Ltd. | 63,660 | $1.44M | 0.34% | −50,686−44.3% | Reduced |
| Alps Advisors Inc | 62,815 | $1.42M | 0.01% | −4,946−7.3% | Reduced |
| The PNC Financial Services Group, Inc. | 54,052 | $1.22M | 0.00% | −4,804−8.2% | Reduced |
| PDT Partners, LLC | 53,951 | $1.22M | 0.08% | −106,107−66.3% | Reduced |
| Simplex Trading, LLC | 53,901 | $1.22M | 0.03% | −2,033−3.6% | Reduced |
| Campbell & CO Investment Adviser LLC | 53,540 | $1.21M | 0.09% | +53,540 | New |
| JPMorgan Chase & Co | 53,516 | $1.21M | 0.00% | −181,285−77.2% | Reduced |
| DekaBank Deutsche Girozentrale | 55,000 | $1.20M | 0.00% | 00.0% | Unchanged |
| Squarepoint Ops LLC | 52,834 | $1.20M | 0.00% | −276,558−84.0% | Reduced |
| Natixis | 52,239 | $1.18M | 0.01% | −38,427−42.4% | Reduced |
| Highland Capital Management, LLC | 50,133 | $1.13M | 0.06% | +50,133 | New |
| New York State Common Retirement Fund | 48,837 | $1.11M | 0.00% | −10,042−17.1% | Reduced |
| T. Rowe Price Investment Management, Inc. | 48,756 | $1.10M | 0.00% | −552−1.1% | Reduced |
| Treasurer of the State of North Carolina | 48,466 | $1.10M | 0.00% | −1,892−3.8% | Reduced |
| Quantinno Capital Management LP | 48,419 | $1.10M | 0.00% | +48,419 | New |
| Police & Firemen's Retirement System of New Jersey | 48,370 | $1.09M | 0.01% | +7,416+18.1% | Added |
| Hennion & Walsh Asset Management, Inc. | 48,129 | $1.09M | 0.04% | −885−1.8% | Reduced |
| Schonfeld Strategic Advisors LLC | 47,282 | $1.07M | 0.01% | −36,634−43.7% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 46,113 | $1.04M | 0.00% | +20,840+82.5% | Added |
| Mariner, LLC | 43,239 | $978.5K | 0.00% | +6,909+19.0% | Added |
| Handelsbanken Fonder AB | 39,100 | $885.0K | 0.00% | +8,900+29.5% | Added |
| Mercer Global Advisors Inc | 39,043 | $883.5K | 0.00% | +18,102+86.4% | Added |
| Point72 Hong Kong Ltd | 37,941 | $858.6K | 0.04% | +37,941 | New |
| Nomura Holdings Inc | 36,600 | $828.3K | 0.00% | +36,600 | New |
| Creative Planning | 35,645 | $806.6K | 0.00% | +13,807+63.2% | Added |
| Vident Advisory, LLC | 35,381 | $800.7K | 0.01% | +35,381 | New |
| Profund Advisors LLC | 34,712 | $785.5K | 0.03% | +6,036+21.0% | Added |
| Janus Henderson Group PLC | 34,412 | $778.7K | 0.00% | 00.0% | Unchanged |
| Scientech Research LLC | 34,182 | $773.5K | 0.27% | +34,182 | New |
| Guggenheim Capital LLC | 33,834 | $765.7K | 0.01% | −4,619−12.0% | Reduced |
| Public Employees Retirement System of Ohio | 33,679 | $762.2K | 0.00% | +209+0.6% | Added |
| Pallas Capital Advisors LLC | 33,077 | $748.5K | 0.03% | −21,772−39.7% | Reduced |
| Voleon Capital Management LP | 32,221 | $729.2K | 0.02% | −10,918−25.3% | Reduced |
| Gsa Capital Partners LLP | 31,446 | $712.0K | 0.06% | +31,446 | New |
| Fox Run Management, L.L.C. | 27,223 | $616.1K | 0.10% | +13,256+94.9% | Added |
| Bayesian Capital Management, LP | 25,500 | $577.1K | 0.12% | +25,500 | New |
| Virginia Retirement Systems Et Al | 25,465 | $576.3K | 0.00% | −2,200−8.0% | Reduced |
| Erste Asset Management GmbH | 25,300 | $573.0K | 0.01% | −16,700−39.8% | Reduced |
| HAP Trading, LLC | 24,763 | $560.4K | 0.15% | +24,763 | New |
| Entropy Technologies, LP | 24,603 | $556.8K | 0.04% | +24,603 | New |
| Graham Capital Management, L.P. | 23,196 | $524.9K | 0.02% | −19,895−46.2% | Reduced |
| Quest Partners LLC | 23,099 | $522.7K | 0.03% | +1,859+8.8% | Added |
| Virtus Investment Advisers, Inc. | 23,073 | $522.1K | 0.15% | 00.0% | Unchanged |
| Manufacturers Life Insurance Company, The | 22,709 | $513.9K | 0.00% | +736+3.3% | Added |
| Arizona State Retirement System | 22,298 | $504.6K | 0.00% | +315+1.4% | Added |
| PharVision Advisers, LLC | 22,291 | $504.4K | 0.28% | +22,291 | New |
| China Universal Asset Management Co., Ltd. | 22,137 | $501.0K | 0.04% | −3,106−12.3% | Reduced |
| Colony Group, LLC | 21,771 | $492.2K | 0.00% | −7,905−26.6% | Reduced |
| Capstone Investment Advisors, LLC | 21,371 | $483.6K | 0.00% | +9,671+82.7% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 21,317 | $482.4K | 0.00% | +2,189+11.4% | Added |
| Captrust Financial Advisors | 21,111 | $477.7K | 0.00% | −8,421−28.5% | Reduced |
| Bayforest Capital Ltd | 20,853 | $471.9K | 0.22% | −35,786−63.2% | Reduced |
| ADAR1 Capital Management, LLC | 20,000 | $452.6K | 0.04% | +3,000+17.6% | Added |
| Merit Financial Group, LLC | 19,544 | $442.3K | 0.00% | −1,552−7.4% | Reduced |
| Brighton Jones LLC | 19,214 | $434.8K | 0.01% | +2,675+16.2% | Added |
| Dimensional Fund Advisors LP | 18,690 | $423.0K | 0.00% | +18,690 | New |
| Teacher Retirement System of Texas | 18,512 | $418.9K | 0.00% | −1,775−8.7% | Reduced |
| FMR LLC | 18,503 | $418.7K | 0.00% | −789−4.1% | Reduced |
| Corton Capital Inc. | 18,427 | $417.0K | 1.03% | −2,584−12.3% | Reduced |
| Buckingham Strategic Partners | 19,919 | $409.3K | 0.00% | −4,431−18.2% | Reduced |
| Concentric Capital Strategies, LP | 17,979 | $406.9K | 0.02% | +17,979 | New |
| Great West Life Assurance Co | 17,747 | $402.0K | 0.00% | +11,558+186.8% | Added |
| Essential Partners LLC | 17,759 | $401.9K | 0.13% | −6,143−25.7% | Reduced |
| Xponance, Inc. | 17,483 | $395.6K | 0.00% | −875−4.8% | Reduced |
| SummitTX Capital, L.P. | 17,232 | $390.0K | 0.02% | +17,232 | New |
| Duncan Williams Asset Management, LLC | 17,005 | $384.8K | 0.11% | 00.0% | Unchanged |
| Allianz Asset Management GmbH | 17,000 | $384.7K | 0.00% | +17,000 | New |
| Ensign Peak Advisors, Inc | 16,547 | $374.5K | 0.00% | −12,850−43.7% | Reduced |
| Quarry LP | 16,022 | $362.6K | 0.09% | +11,022+220.4% | Added |
| KLP Kapitalforvaltning AS | 15,600 | $353.0K | 0.00% | 00.0% | Unchanged |
| Sherbrooke Park Advisers LLC | 15,590 | $352.8K | 0.16% | −349−2.2% | Reduced |
| Victory Capital Management Inc | 15,272 | $345.6K | 0.00% | −303−1.9% | Reduced |
| HSBC Holdings PLC | 15,025 | $344.7K | 0.00% | −42,873−74.0% | Reduced |
| Group One Trading, L.P. | 14,925 | $337.8K | 0.01% | −1,853−11.0% | Reduced |
| Point72 (DIFC) Ltd | 14,591 | $330.2K | 0.02% | +14,591 | New |
| Wolverine Trading, LLC | 14,480 | $328.0K | 0.01% | −1,718−10.6% | Reduced |
| XTX Topco Ltd | 14,407 | $326.0K | 0.02% | +14,407 | New |
| Aigen Investment Management, LP | 14,181 | $320.9K | 0.05% | +14,181 | New |
| Birchview Capital, LP | 14,000 | $316.8K | 0.24% | 00.0% | Unchanged |
| Empowered Funds, LLC | 13,341 | $301.9K | 0.00% | −146−1.1% | Reduced |
| M&T Bank Corp | 13,025 | $295.5K | 0.00% | +13,025 | New |
| Wedmont Private Capital | 11,415 | $287.8K | 0.01% | +11,415 | New |
| Acadian Asset Management LLC | 12,453 | $280.0K | 0.00% | +2,371+23.5% | Added |
| Compagnie Lombard Odier SCmA | 11,000 | $248.9K | 0.00% | 00.0% | Unchanged |
| Caxton Associates LLP | 10,969 | $248.2K | 0.01% | +10,969 | New |
| Walleye Trading LLC | 10,441 | $236.3K | 0.00% | +9,680+1,272.0% | Added |
| Summit Trail Advisors, LLC | 10,276 | $232.5K | 0.00% | +10,276 | New |
| Integrated Wealth Concepts LLC | 10,190 | $230.6K | 0.00% | −2,393−19.0% | Reduced |
| Russell Investments Group, Ltd. | 9,901 | $224.1K | 0.00% | −24−0.2% | Reduced |
| Lecap Asset Management Ltd | 9,868 | $223.3K | 0.08% | +9,868 | New |
| Financiere des Professionnels - Fonds d,investissement inc. | 9,439 | $213.6K | 0.01% | +9,439 | New |