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Apellis Pharmaceuticals, Inc.

APLSDelisted May 14, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q3 2025

Institutional positions in Apellis Pharmaceuticals, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
273
+31 vs. Q2 2025
Shares held
122.3M
−5.96M (−4.6%) vs. Q2 2025
Total value
$2.77B
+$549.5M (+24.7%) vs. Q2 2025
New holders
61
92 more added
Sold out
30
91 more reduced

5 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 273 institutions
Q1 2021: 175 institutionsQ2 2021: 205 institutionsQ3 2021: 181 institutionsQ4 2021: 187 institutionsQ1 2022: 212 institutionsQ2 2022: 212 institutionsQ3 2022: 250 institutionsQ4 2022: 244 institutionsQ1 2023: 282 institutionsQ2 2023: 317 institutionsQ3 2023: 256 institutionsQ4 2023: 284 institutionsQ1 2024: 302 institutionsQ2 2024: 263 institutionsQ3 2024: 265 institutionsQ4 2024: 260 institutionsQ1 2025: 255 institutionsQ2 2025: 247 institutionsQ3 2025: 273 institutionsQ4 2025: 280 institutionsQ1 2026: 324 institutionsQ2 2026: 1 institution
Value heldQ3 2025: $2.77B
Q1 2021: $2.80BQ2 2021: $4.08BQ3 2021: $2.29BQ4 2021: $3.83BQ1 2022: $4.62BQ2 2022: $4.15BQ3 2022: $6.66BQ4 2022: $5.20BQ1 2023: $7.28BQ2 2023: $9.71BQ3 2023: $4.34BQ4 2023: $6.82BQ1 2024: $6.65BQ2 2024: $4.43BQ3 2024: $3.41BQ4 2024: $4.04BQ1 2025: $2.80BQ2 2025: $2.28BQ3 2025: $2.77BQ4 2025: $3.17BQ1 2026: $5.56BQ2 2026: $10.2K
Institutions holding APLS and their total value by quarter
QuarterHoldersValue
Q2 20261$10.2K
Q1 2026324$5.56B
Q4 2025280$3.17B
Q3 2025273$2.77B
Q2 2025247$2.28B
Q1 2025255$2.80B
Q4 2024260$4.04B
Q3 2024265$3.41B
Q2 2024263$4.43B
Q1 2024302$6.65B
Q4 2023284$6.82B
Q3 2023256$4.34B
Q2 2023317$9.71B
Q1 2023282$7.28B
Q4 2022244$5.20B
Q3 2022250$6.66B
Q2 2022212$4.15B
Q1 2022212$4.62B
Q4 2021187$3.83B
Q3 2021181$2.29B
Q2 2021205$4.08B
Q1 2021175$2.80B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q2 2025.

Institutions holding APLS in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Smartleaf Asset Management LLC1$220.00%+1New
Activest Wealth Management1$230.00%−22−95.7%Reduced
Manchester Capital Management LLC3$680.00%00.0%Unchanged
Transamerica Financial Advisors, Inc.3$680.00%+3New
Wealthspire Advisors, LLC4$910.00%+4New
WPG Advisers, LLC5$1130.00%00.0%Unchanged
MV Capital Management, Inc.8$1820.00%00.0%Unchanged
Cromwell Holdings LLC10$2270.00%+10New
Rothschild Investment LLC12$2720.00%+12New
South State Corp.15$3400.00%00.0%Unchanged
Rise Advisors, LLC18$4070.00%+18New
Bell Investment Advisors, Inc19$4300.00%+19New
Global Retirement Partners, LLC20$4530.00%+14+233.3%Added
Bare Financial Services, Inc21$4750.00%+21New
Kilter Group LLC23$5210.00%+23New
Parkside Financial Bank & Trust36$8150.00%00.0%Unchanged
Capital Analysts, LLC57$1.00K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC50$1.13K0.00%00.0%Unchanged
Sachetta, LLC60$1.36K0.00%00.0%Unchanged
Sunbelt Securities, Inc.84$1.90K0.00%+84New
Atlantic Trust, LLC86$1.95K0.00%+76+760.0%Added
Crewe Advisors LLC88$1.99K0.00%+88New
SBI Securities Co., Ltd.93$2.10K0.00%+2+2.2%Added
TD Private Client Wealth LLC94$2.13K0.00%−8−7.8%Reduced
Brown Brothers Harriman & Co95$2.15K0.00%00.0%Unchanged
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.97$2.19K0.00%00.0%Unchanged
Sofos Investments, Inc.100$2.26K0.00%+100New
Capital Advisors, Ltd. LLC136$3.00K0.00%+136New
Evelyn Partners Investment Management LLP150$3.39K0.00%00.0%Unchanged
Advisory Services Network, LLC159$3.60K0.00%+159New
Sterling Capital Management LLC164$3.71K0.00%−1−0.6%Reduced
Quadrant Capital Group LLC169$3.83K0.00%+169New
Massmutual Trust Co FSB181$4.10K0.00%+75+70.8%Added
GAMMA Investing LLC230$5.21K0.00%+152+194.9%Added
Farther Finance Advisors, LLC332$7.51K0.00%+266+403.0%Added
Comerica Bank366$8.28K0.00%+51+16.2%Added
CIBC Private Wealth Group, LLC377$8.53K0.00%−3,127−89.2%Reduced
Larson Financial Group LLC393$8.89K0.00%+390+13,000.0%Added
Daiwa Securities Group Inc.429$10.0K0.00%00.0%Unchanged
Quent Capital, LLC445$10.1K0.00%+445New
Archer Investment Corp500$11.3K0.00%00.0%Unchanged
Aster Capital Management (DIFC) Ltd555$12.6K0.01%−62−10.0%Reduced
Versant Capital Management, Inc573$13.0K0.00%−31−5.1%Reduced
BNP PARIBAS ASSET MANAGEMENT Holding S.A.594$13.0K0.00%00.0%Unchanged
Atlantic Private Wealth, LLC600$13.6K0.01%00.0%Unchanged
Northwestern Mutual Wealth Management Co601$13.6K0.00%+1+0.2%Added
True Wealth Design, LLC946$21.4K0.01%+379+66.8%Added
Rockefeller Capital Management L.P.1,030$23.3K0.00%+1,030New
IFP Advisors, Inc1,109$25.1K0.00%+35+3.3%Added
Leonteq Securities AG1,119$25.3K0.00%−102−8.4%Reduced
Signaturefd, LLC1,489$33.7K0.00%+291+24.3%Added
Clearstead Advisors, LLC1,719$38.9K0.00%−1,392−44.7%Reduced
Parallel Advisors, LLC1,970$44.6K0.00%+46+2.4%Added
Jones Financial Companies LLLP2,037$45.6K0.00%+1,373+206.8%Added
Allworth Financial LP2,194$49.7K0.00%+857+64.1%Added
KBC Group NV2,313$52.0K0.00%00.0%Unchanged
Wells Fargo & Company2,463$55.7K0.00%−1,041,192−99.8%Reduced
STRS Ohio2,578$58.3K0.00%+10.0%Added
US Bancorp2,666$60.3K0.00%−390−12.8%Reduced
GF Fund Management Co. Ltd.2,717$61.5K0.00%−468−14.7%Reduced
Quantbot Technologies LP2,813$63.7K0.00%+2,813New
Advisor Group Holdings, Inc.3,154$80.0K0.00%+472+17.6%Added
Covestor Ltd4,088$93.0K0.05%−512−11.1%Reduced
EverSource Wealth Advisors, LLC4,865$110.1K0.00%−564−10.4%Reduced
Mirae Asset Global Investments Co., Ltd.4,882$110.5K0.00%+27+0.6%Added
Stelac Advisory Services LLC5,520$124.9K0.04%+5,520New
MetLife Investment Management6,902$156.2K0.00%+199+3.0%Added
Tower Research Capital LLC (TRC)7,395$167.3K0.00%+5,828+371.9%Added
Public Employees Retirement Association of Colorado8,362$189.0K0.00%00.0%Unchanged
Mirae Asset Global ETFs Holdings Ltd.8,609$195.0K0.00%−32,375−79.0%Reduced
Amalgamated Bank8,674$196.0K0.00%+563+6.9%Added
Twinbeech Capital LP8,927$202.0K0.01%+8,927New
Keybank National Association9,084$205.6K0.00%+9,084New
Financiere des Professionnels - Fonds d,investissement inc.9,439$213.6K0.01%+9,439New
Lecap Asset Management Ltd9,868$223.3K0.08%+9,868New
Russell Investments Group, Ltd.9,901$224.1K0.00%−24−0.2%Reduced
Integrated Wealth Concepts LLC10,190$230.6K0.00%−2,393−19.0%Reduced
Summit Trail Advisors, LLC10,276$232.5K0.00%+10,276New
Walleye Trading LLC10,441$236.3K0.00%+9,680+1,272.0%Added
Caxton Associates LLP10,969$248.2K0.01%+10,969New
Compagnie Lombard Odier SCmA11,000$248.9K0.00%00.0%Unchanged
Acadian Asset Management LLC12,453$280.0K0.00%+2,371+23.5%Added
Wedmont Private Capital11,415$287.8K0.01%+11,415New
M&T Bank Corp13,025$295.5K0.00%+13,025New
Empowered Funds, LLC13,341$301.9K0.00%−146−1.1%Reduced
Birchview Capital, LP14,000$316.8K0.24%00.0%Unchanged
Aigen Investment Management, LP14,181$320.9K0.05%+14,181New
XTX Topco Ltd14,407$326.0K0.02%+14,407New
Wolverine Trading, LLC14,480$328.0K0.01%−1,718−10.6%Reduced
Point72 (DIFC) Ltd14,591$330.2K0.02%+14,591New
Group One Trading, L.P.14,925$337.8K0.01%−1,853−11.0%Reduced
HSBC Holdings PLC15,025$344.7K0.00%−42,873−74.0%Reduced
Victory Capital Management Inc15,272$345.6K0.00%−303−1.9%Reduced
Sherbrooke Park Advisers LLC15,590$352.8K0.16%−349−2.2%Reduced
KLP Kapitalforvaltning AS15,600$353.0K0.00%00.0%Unchanged
Quarry LP16,022$362.6K0.09%+11,022+220.4%Added
Ensign Peak Advisors, Inc16,547$374.5K0.00%−12,850−43.7%Reduced
Allianz Asset Management GmbH17,000$384.7K0.00%+17,000New
Duncan Williams Asset Management, LLC17,005$384.8K0.11%00.0%Unchanged
SummitTX Capital, L.P.17,232$390.0K0.02%+17,232New