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Apellis Pharmaceuticals, Inc.

APLSDelisted May 14, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q2 2025

Institutional positions in Apellis Pharmaceuticals, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
247
−6 vs. Q1 2025
Shares held
131.5M
+3.54M (+2.8%) vs. Q1 2025
Total value
$2.28B
−$523.6M (−18.7%) vs. Q1 2025
New holders
43
108 more added
Sold out
49
68 more reduced

2 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 247 institutions
Q1 2021: 175 institutionsQ2 2021: 205 institutionsQ3 2021: 181 institutionsQ4 2021: 187 institutionsQ1 2022: 212 institutionsQ2 2022: 212 institutionsQ3 2022: 250 institutionsQ4 2022: 244 institutionsQ1 2023: 282 institutionsQ2 2023: 317 institutionsQ3 2023: 256 institutionsQ4 2023: 284 institutionsQ1 2024: 302 institutionsQ2 2024: 263 institutionsQ3 2024: 265 institutionsQ4 2024: 260 institutionsQ1 2025: 255 institutionsQ2 2025: 247 institutionsQ3 2025: 273 institutionsQ4 2025: 280 institutionsQ1 2026: 324 institutionsQ2 2026: 1 institution
Value heldQ2 2025: $2.28B
Q1 2021: $2.80BQ2 2021: $4.08BQ3 2021: $2.29BQ4 2021: $3.83BQ1 2022: $4.62BQ2 2022: $4.15BQ3 2022: $6.66BQ4 2022: $5.20BQ1 2023: $7.28BQ2 2023: $9.71BQ3 2023: $4.34BQ4 2023: $6.82BQ1 2024: $6.65BQ2 2024: $4.43BQ3 2024: $3.41BQ4 2024: $4.04BQ1 2025: $2.80BQ2 2025: $2.28BQ3 2025: $2.77BQ4 2025: $3.17BQ1 2026: $5.56BQ2 2026: $10.2K
Institutions holding APLS and their total value by quarter
QuarterHoldersValue
Q2 20261$10.2K
Q1 2026324$5.56B
Q4 2025280$3.17B
Q3 2025273$2.77B
Q2 2025247$2.28B
Q1 2025255$2.80B
Q4 2024260$4.04B
Q3 2024265$3.41B
Q2 2024263$4.43B
Q1 2024302$6.65B
Q4 2023284$6.82B
Q3 2023256$4.34B
Q2 2023317$9.71B
Q1 2023282$7.28B
Q4 2022244$5.20B
Q3 2022250$6.66B
Q2 2022212$4.15B
Q1 2022212$4.62B
Q4 2021187$3.83B
Q3 2021181$2.29B
Q2 2021205$4.08B
Q1 2021175$2.80B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q1 2025.

Institutions holding APLS in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Bleakley Financial Group, LLC77,088$1.33M0.03%+3,951+5.4%Added
Ikarian Capital, LLC75,000$1.30M0.43%00.0%Unchanged
Raymond James Financial Inc74,466$1.29M0.00%+22,488+43.3%Added
Mackenzie Financial Corp74,165$1.28M0.00%+32,632+78.6%Added
Phocas Financial Corp.71,599$1.24M0.18%+71,599New
Alps Advisors Inc67,761$1.17M0.01%+67,761New
Landscape Capital Management, L.L.C.64,521$1.12M0.09%+25,533+65.5%Added
New York State Common Retirement Fund58,879$1.02M0.00%+10,042+20.6%Added
The PNC Financial Services Group, Inc.58,856$1.02M0.00%+465+0.8%Added
Engineers Gate Manager LP58,718$1.02M0.01%+16,546+39.2%Added
HSBC Holdings PLC57,898$1.00M0.00%+32,899+131.6%Added
Bayforest Capital Ltd56,639$980.4K0.43%+4,301+8.2%Added
Healthcare of Ontario Pension Plan Trust Fund56,000$969.4K0.00%+56,000New
Simplex Trading, LLC55,934$968.0K0.03%+55,934New
Pallas Capital Advisors LLC54,849$949.4K0.04%+12,315+29.0%Added
DekaBank Deutsche Girozentrale55,000$921.0K0.00%00.0%Unchanged
Treasurer of the State of North Carolina50,358$872.0K0.00%+1,353+2.8%Added
T. Rowe Price Investment Management, Inc.49,308$854.0K0.00%+1,595+3.3%Added
Hennion & Walsh Asset Management, Inc.49,014$848.4K0.03%+4,848+11.0%Added
Cinctive Capital Management LP47,700$825.7K0.05%+47,700New
SG Americas Securities, LLC45,103$781.0K0.00%−321,041−87.7%Reduced
Voleon Capital Management LP43,139$746.7K0.04%+12,948+42.9%Added
Graham Capital Management, L.P.43,091$745.9K0.02%+14,955+53.2%Added
Erste Asset Management GmbH42,000$732.1K0.01%00.0%Unchanged
Mirae Asset Global ETFs Holdings Ltd.40,984$710.3K0.00%+11,425+38.7%Added
Police & Firemen's Retirement System of New Jersey40,954$708.9K0.01%+2,385+6.2%Added
Wealthedge Investment Advisors, LLC38,572$667.7K0.28%+38,572New
Guggenheim Capital LLC38,453$665.6K0.01%+3,105+8.8%Added
Mariner, LLC36,330$628.9K0.00%+23,326+179.4%Added
Janus Henderson Group PLC34,412$595.3K0.00%00.0%Unchanged
Public Employees Retirement System of Ohio33,470$579.4K0.00%+495+1.5%Added
Alliancebernstein L.P.31,929$552.7K0.00%−12,983−28.9%Reduced
Prelude Capital Management, LLC31,139$539.0K0.05%+31,139New
Handelsbanken Fonder AB30,200$523.0K0.00%−400−1.3%Reduced
Colony Group, LLC29,676$513.7K0.00%+7,793+35.6%Added
Captrust Financial Advisors29,532$511.2K0.00%+252+0.9%Added
Ensign Peak Advisors, Inc29,397$508.9K0.00%00.0%Unchanged
Profund Advisors LLC28,676$496.4K0.02%−6,981−19.6%Reduced
Virginia Retirement Systems Et Al27,665$478.9K0.00%+3,000+12.2%Added
First Trust Advisors LP26,538$459.4K0.00%−172,671−86.7%Reduced
Universal- Beteiligungs- und Servicegesellschaft mbH25,273$437.5K0.00%+9,114+56.4%Added
China Universal Asset Management Co., Ltd.25,243$437.0K0.04%+67+0.3%Added
Parallax Volatility Advisers, L.P.24,443$423.1K0.02%−3,907−13.8%Reduced
Buckingham Strategic Partners24,350$421.5K0.01%+7,783+47.0%Added
Essential Partners LLC23,902$413.7K0.17%+23,902New
Toronto Dominion Bank23,437$405.7K0.00%−138,753−85.5%Reduced
Virtus Investment Advisers, Inc.23,073$399.4K0.14%+12,106+110.4%Added
Boothbay Fund Management, LLC22,997$398.1K0.01%00.0%Unchanged
SEI Investments Co22,359$387.0K0.00%+22,359New
Arizona State Retirement System21,983$380.5K0.00%+2,444+12.5%Added
Manufacturers Life Insurance Company, The21,973$380.4K0.00%−2,964−11.9%Reduced
Creative Planning21,838$378.0K0.00%+21,838New
Quest Partners LLC21,240$367.7K0.04%−34,864−62.1%Reduced
Two Sigma Securities, LLC21,168$366.4K0.05%+21,168New
Merit Financial Group, LLC21,096$365.2K0.00%−12,666−37.5%Reduced
Corton Capital Inc.21,011$363.7K0.42%+21,011New
Mercer Global Advisors Inc20,941$362.5K0.00%−821−3.8%Reduced
Teacher Retirement System of Texas20,287$351.2K0.00%+1,828+9.9%Added
FMR LLC19,292$333.9K0.00%−1,483,917−98.7%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)19,128$331.1K0.00%−763−3.8%Reduced
Xponance, Inc.18,358$317.8K0.00%+2,261+14.0%Added
HAP Trading, LLC17,937$310.5K0.14%+17,937New
Duncan Williams Asset Management, LLC17,005$294.4K0.09%−4,120−19.5%Reduced
ADAR1 Capital Management, LLC17,000$294.3K0.05%00.0%Unchanged
Quadrature Capital Ltd16,798$290.6K0.01%+16,798New
Group One Trading, L.P.16,778$290.4K0.01%−13,263−44.1%Reduced
Brighton Jones LLC16,539$286.3K0.01%+16,539New
Wolverine Trading, LLC16,198$282.3K0.01%+2,770+20.6%Added
E Fund Management Co., Ltd.16,057$277.9K0.01%−778−4.6%Reduced
Sherbrooke Park Advisers LLC15,939$275.9K0.12%+15,939New
KLP Kapitalforvaltning AS15,600$270.0K0.00%+2,600+20.0%Added
Victory Capital Management Inc15,575$269.6K0.00%−199,577−92.8%Reduced
Birchview Capital, LP14,000$242.3K0.24%00.0%Unchanged
Fox Run Management, L.L.C.13,967$241.8K0.04%−1,745−11.1%Reduced
Empowered Funds, LLC13,487$233.5K0.00%+13,487New
Integrated Wealth Concepts LLC12,583$217.8K0.00%+12,583New
111 Capital12,400$214.6K0.04%−4,436−26.3%Reduced
Capstone Investment Advisors, LLC11,700$202.5K0.00%+11,700New
Compagnie Lombard Odier SCmA11,000$190.4K0.00%00.0%Unchanged
Renaissance Technologies LLC10,988$190.2K0.00%+10,988New
Acadian Asset Management LLC10,082$174.0K0.00%−13,894−57.9%Reduced
Eastern Bank10,000$173.1K0.00%−11,500−53.5%Reduced
Russell Investments Group, Ltd.9,925$171.8K0.00%−28,978−74.5%Reduced
Wexford Capital LP9,139$158.2K0.04%+9,139New
Public Employees Retirement Association of Colorado8,362$145.0K0.00%00.0%Unchanged
Amalgamated Bank8,111$140.0K0.00%+866+12.0%Added
Headlands Technologies LLC6,892$119.3K0.01%+6,080+748.8%Added
MetLife Investment Management6,703$116.0K0.00%+117+1.8%Added
Great West Life Assurance Co6,189$107.0K0.00%00.0%Unchanged
EverSource Wealth Advisors, LLC5,429$94.0K0.00%+4,191+338.5%Added
Quarry LP5,000$86.5K0.02%+5,000New
Mirae Asset Global Investments Co., Ltd.4,855$84.0K0.00%+655+15.6%Added
Covestor Ltd4,600$80.0K0.05%+605+15.1%Added
CIBC Private Wealth Group, LLC3,504$60.7K0.00%−15,360−81.4%Reduced
GF Fund Management Co. Ltd.3,185$55.1K0.00%00.0%Unchanged
Clearstead Advisors, LLC3,111$53.9K0.00%+1,300+71.8%Added
US Bancorp3,056$52.9K0.00%+711+30.3%Added
Advisor Group Holdings, Inc.2,682$46.6K0.00%+1,570+141.2%Added
STRS Ohio2,577$44.6K0.00%+2,577New
KBC Group NV2,313$40.0K0.00%−1,537−39.9%Reduced