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Apellis Pharmaceuticals, Inc.

APLSDelisted May 14, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in Apellis Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
280
+14 vs. Q3 2025
Shares held
126.4M
+4.65M (+3.8%) vs. Q3 2025
Total value
$3.17B
+$415.1M (+15.0%) vs. Q3 2025
New holders
61
89 more added
Sold out
47
102 more reduced

7 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 280 institutions
Q1 2021: 175 institutionsQ2 2021: 205 institutionsQ3 2021: 181 institutionsQ4 2021: 187 institutionsQ1 2022: 212 institutionsQ2 2022: 212 institutionsQ3 2022: 250 institutionsQ4 2022: 244 institutionsQ1 2023: 282 institutionsQ2 2023: 317 institutionsQ3 2023: 256 institutionsQ4 2023: 284 institutionsQ1 2024: 302 institutionsQ2 2024: 263 institutionsQ3 2024: 265 institutionsQ4 2024: 260 institutionsQ1 2025: 255 institutionsQ2 2025: 247 institutionsQ3 2025: 273 institutionsQ4 2025: 280 institutionsQ1 2026: 324 institutionsQ2 2026: 1 institution
Value heldQ4 2025: $3.17B
Q1 2021: $2.80BQ2 2021: $4.08BQ3 2021: $2.29BQ4 2021: $3.83BQ1 2022: $4.62BQ2 2022: $4.15BQ3 2022: $6.66BQ4 2022: $5.20BQ1 2023: $7.28BQ2 2023: $9.71BQ3 2023: $4.34BQ4 2023: $6.82BQ1 2024: $6.65BQ2 2024: $4.43BQ3 2024: $3.41BQ4 2024: $4.04BQ1 2025: $2.80BQ2 2025: $2.28BQ3 2025: $2.77BQ4 2025: $3.17BQ1 2026: $5.56BQ2 2026: $10.2K
Institutions holding APLS and their total value by quarter
QuarterHoldersValue
Q2 20261$10.2K
Q1 2026324$5.56B
Q4 2025280$3.17B
Q3 2025273$2.77B
Q2 2025247$2.28B
Q1 2025255$2.80B
Q4 2024260$4.04B
Q3 2024265$3.41B
Q2 2024263$4.43B
Q1 2024302$6.65B
Q4 2023284$6.82B
Q3 2023256$4.34B
Q2 2023317$9.71B
Q1 2023282$7.28B
Q4 2022244$5.20B
Q3 2022250$6.66B
Q2 2022212$4.15B
Q1 2022212$4.62B
Q4 2021187$3.83B
Q3 2021181$2.29B
Q2 2021205$4.08B
Q1 2021175$2.80B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q3 2025.

Institutions holding APLS in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Colony Group, LLC0$00.00%−21,771−100.0%Sold out
Capstone Investment Advisors, LLC0$00.00%−21,371−100.0%Sold out
Captrust Financial Advisors0$00.00%−21,111−100.0%Sold out
Bayforest Capital Ltd0$00.00%−20,853−100.0%Sold out
Merit Financial Group, LLC0$00.00%−19,544−100.0%Sold out
Brighton Jones LLC0$00.00%−19,214−100.0%Sold out
Buckingham Strategic Partners0$00.00%−19,919−100.0%Sold out
Concentric Capital Strategies, LP0$00.00%−17,979−100.0%Sold out
SummitTX Capital, L.P.0$00.00%−17,232−100.0%Sold out
Sherbrooke Park Advisers LLC0$00.00%−15,590−100.0%Sold out
HSBC Holdings PLC0$00.00%−15,025−100.0%Sold out
Group One Trading, L.P.0$00.00%−14,925−100.0%Sold out
XTX Topco Ltd0$00.00%−14,407−100.0%Sold out
Aigen Investment Management, LP0$00.00%−14,181−100.0%Sold out
Compagnie Lombard Odier SCmA0$00.00%−11,000−100.0%Sold out
Caxton Associates LLP0$00.00%−10,969−100.0%Sold out
Integrated Wealth Concepts LLC0$00.00%−10,190−100.0%Sold out
Lecap Asset Management Ltd0$00.00%−9,868−100.0%Sold out
Financiere des Professionnels - Fonds d,investissement inc.0$00.00%−9,439−100.0%Sold out
Keybank National Association0$00.00%−9,084−100.0%Sold out
Advisory Services Network, LLC0$00.00%−159−100.0%Sold out
Kilter Group LLC0$00.00%−23−100.0%Sold out
Bell Investment Advisors, Inc0$00.00%−19−100.0%Sold out
Rise Advisors, LLC0$00.00%−18−100.0%Sold out
Cromwell Holdings LLC0$00.00%−10−100.0%Sold out
Wealthspire Advisors, LLC0$00.00%−4−100.0%Sold out
Activest Wealth Management0$00.00%−1−100.0%Sold out
Cubist Systematic Strategies, LLC––––Not filed
EFG Asset Management (North America) Corp.––––Not filed
Point72 Hong Kong Ltd––––Not filed
HAP Trading, LLC––––Not filed
Corton Capital Inc.––––Not filed
Point72 (DIFC) Ltd––––Not filed
Wolverine Trading, LLC––––Not filed