Alpine Immune Sciences, Inc.
ALPNDelisted May 20, 2024- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001626199
Alpine Immune Sciences, Inc. was delisted on May 20, 2024; its insiders filed their last Form 4 on May 20, 2024; 180 institutions reported holding it in 13F filings for Q1 2024, worth $2.56B in total; no superinvestor held it.
13F holders, Q1 2024
Institutional positions in Alpine Immune Sciences, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
ALPN is no longer listed, so this page shows Q1 2024. 13F filings for later quarters list far fewer holders.
- Institutional holders
- 180
- +47 vs. Q4 2023
- Shares held
- 64.6M
- +5.65M (+9.6%) vs. Q4 2023
- Total value
- $2.56B
- +$1.44B (+128.0%) vs. Q4 2023
- New holders
- 63
- 67 more added
- Sold out
- 16
- 41 more reduced
Compare with Q4 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ALPN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 0 | $0 |
| Q1 2026 | 0 | $0 |
| Q4 2025 | 0 | $0 |
| Q3 2025 | 0 | $0 |
| Q2 2025 | 0 | $0 |
| Q1 2025 | 0 | $0 |
| Q4 2024 | 0 | $0 |
| Q3 2024 | 0 | $0 |
| Q2 2024 | 0 | $0 |
| Q1 2024 | 180 | $2.56B |
| Q4 2023 | 133 | $1.12B |
| Q3 2023 | 88 | $525.8M |
| Q2 2023 | 77 | $449.3M |
| Q1 2023 | 61 | $319.4M |
| Q4 2022 | 64 | $300.8M |
| Q3 2022 | 70 | $284.0M |
| Q2 2022 | 58 | $204.4M |
| Q1 2022 | 56 | $221.8M |
| Q4 2021 | 53 | $257.1M |
| Q3 2021 | 44 | $163.5M |
| Q2 2021 | 47 | $118.5M |
| Q1 2021 | 48 | $145.0M |
Institutions, Q1 2024
Shares, value and share of portfolio for each institution holding Alpine Immune Sciences, Inc.; share changes are against Q4 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Rhumbline Advisers | 54,543 | $2.16M | 0.00% | +10,822+24.8% | Added |
| Swiss National Bank | 63,500 | $2.52M | 0.00% | +6,300+11.0% | Added |
| Boothbay Fund Management, LLC | 67,972 | $2.69M | 0.08% | −48,851−41.8% | Reduced |
| EAM Investors, LLC | 74,899 | $2.97M | 0.47% | −87,786−54.0% | Reduced |
| Raymond James Financial Services Advisors, Inc. | 76,508 | $3.03M | 0.00% | +76,508 | New |
| BNP Paribas Arbitrage, SA | 77,784 | $3.08M | 0.00% | −29,157−27.3% | Reduced |
| Altium Capital Management LP | 77,848 | $3.09M | 1.38% | −875−1.1% | Reduced |
| Baker Bros. Advisors LP | 81,578 | $3.23M | 0.04% | +81,578 | New |
| Manufacturers Life Insurance Company, The | 83,868 | $3.32M | 0.00% | +57,090+213.2% | Added |
| Rhenman & Partners Asset Management AB | 85,500 | $3.39M | 0.32% | +85,500 | New |
| Handelsbanken Fonder AB | 102,000 | $4.04M | 0.02% | +102,000 | New |
| Algert Global LLC | 108,841 | $4.31M | 0.17% | +80,551+284.7% | Added |
| Susquehanna International Group, LLP | 109,860 | $4.35M | 0.01% | +87,085+382.4% | Added |
| Point72 Asset Management, L.P. | 110,700 | $4.39M | 0.01% | +110,700 | New |
| Trexquant Investment LP | 115,776 | $4.59M | 0.09% | +61,996+115.3% | Added |
| Exome Asset Management LLC | 117,000 | $4.64M | 3.97% | −56,500−32.6% | Reduced |
| TD Asset Management Inc | 118,418 | $4.69M | 0.00% | +85,218+256.7% | Added |
| Tri Locum Partners LP | 120,687 | $4.78M | 1.66% | +120,687 | New |
| Hillsdale Investment Management Inc. | 133,960 | $5.31M | 0.42% | +133,960 | New |
| Federated Hermes, Inc. | 138,981 | $5.51M | 0.01% | +138,616+37,977.0% | Added |
| Ensign Peak Advisors, Inc | 140,043 | $5.55M | 0.01% | +10,068+7.7% | Added |
| Citadel Advisors LLC | 142,879 | $5.66M | 0.01% | −732,378−83.7% | Reduced |
| UBS Group AG | 153,473 | $6.08M | 0.00% | +87,666+133.2% | Added |
| Wellington Management Group LLP | 161,145 | $6.39M | 0.00% | +51,263+46.7% | Added |
| Qube Research & Technologies Ltd | 163,323 | $6.47M | 0.01% | −42,443−20.6% | Reduced |
| ExodusPoint Capital Management, LP | 171,251 | $6.79M | 0.08% | −37,723−18.1% | Reduced |
| Jane Street Group, LLC | 177,434 | $7.03M | 0.01% | +107,981+155.5% | Added |
| Dimensional Fund Advisors LP | 191,779 | $7.60M | 0.00% | −42,102−18.0% | Reduced |
| Jennison Associates LLC | 191,974 | $7.61M | 0.01% | +50,879+36.1% | Added |
| Silverarc Capital Management, LLC | 199,020 | $7.89M | 2.21% | −98,769−33.2% | Reduced |
| Bank of America Corp | 202,414 | $8.02M | 0.00% | +110,648+120.6% | Added |
| Deutsche Bank AG | 204,479 | $8.11M | 0.00% | +75,000+57.9% | Added |
| Walleye Capital LLC | 206,104 | $8.17M | 0.09% | −159,836−43.7% | Reduced |
| Citigroup Inc | 207,496 | $8.23M | 0.01% | +171,719+480.0% | Added |
| Integral Health Asset Management, LLC | 230,000 | $9.12M | 0.89% | +230,000 | New |
| Rafferty Asset Management, LLC | 234,625 | $9.30M | 0.03% | +154,463+192.7% | Added |
| FMR LLC | 238,561 | $9.46M | 0.00% | +150.0% | Added |
| Goldman Sachs Group Inc | 240,435 | $9.53M | 0.00% | +42,491+21.5% | Added |
| Renaissance Technologies LLC | 244,981 | $9.71M | 0.02% | +28,296+13.1% | Added |
| Woodline Partners LP | 254,334 | $10.1M | 0.09% | −745,772−74.6% | Reduced |
| Atika Capital Management LLC | 256,000 | $10.1M | 1.14% | +256,000 | New |
| Ikarian Capital, LLC | 261,365 | $10.4M | 2.82% | −225,883−46.4% | Reduced |
| Nan Fung Group Holdings Ltd | 263,940 | $10.5M | 9.69% | 00.0% | Unchanged |
| Voloridge Investment Management, LLC | 267,232 | $10.6M | 0.04% | +33,482+14.3% | Added |
| Invesco Ltd. | 272,627 | $10.8M | 0.00% | +30,851+12.8% | Added |
| Adage Capital Partners GP, L.L.C. | 310,000 | $12.3M | 0.02% | −404,590−56.6% | Reduced |
| Bank of New York Mellon Corp | 325,943 | $12.9M | 0.00% | +223,591+218.5% | Added |
| Charles Schwab Investment Management Inc | 339,142 | $13.4M | 0.00% | +41,690+14.0% | Added |
| Northern Trust Corp | 341,701 | $13.5M | 0.00% | +45,006+15.2% | Added |
| Vestal Point Capital, LP | 350,000 | $13.9M | 1.15% | +350,000 | New |
| Balyasny Asset Management LLC | 372,995 | $14.8M | 0.04% | +372,995 | New |
| Artal Group S.A. | 405,784 | $16.1M | 0.41% | +355,025+699.4% | Added |
| Eventide Asset Management, LLC | 408,542 | $16.2M | 0.25% | +408,542 | New |
| Candriam Luxembourg S.C.A. | 415,000 | $16.5M | 0.11% | −55,000−11.7% | Reduced |
| D. E. Shaw & Co., Inc. | 428,555 | $17.0M | 0.02% | +133,013+45.0% | Added |
| Janus Henderson Group PLC | 450,827 | $17.8M | 0.01% | −132,412−22.7% | Reduced |
| First Light Asset Management, LLC | 501,243 | $19.9M | 1.52% | +501,243 | New |
| Nuveen Asset Management, LLC | 513,175 | $20.3M | 0.01% | +383,209+294.9% | Added |
| Two Sigma Investments, LP | 519,971 | $20.6M | 0.05% | +141,558+37.4% | Added |
| Vivo Capital, LLC | 520,505 | $20.8M | 1.63% | −298,770−36.5% | Reduced |
| Two Sigma Advisers, LP | 668,775 | $26.5M | 0.06% | +404,700+153.3% | Added |
| Morgan Stanley | 789,645 | $31.3M | 0.00% | +70,904+9.9% | Added |
| Geode Capital Management, LLC | 910,599 | $36.1M | 0.00% | +146,252+19.1% | Added |
| Franklin Resources Inc | 1,093,203 | $43.3M | 0.01% | −127,130−10.4% | Reduced |
| Great Point Partners LLC | 1,128,499 | $44.7M | 6.97% | −2,574,934−69.5% | Reduced |
| Avidity Partners Management LP | 1,174,700 | $46.6M | 1.66% | +1,174,700 | New |
| Octagon Capital Advisors LP | 1,241,300 | $49.2M | 5.98% | 00.0% | Unchanged |
| Commodore Capital LP | 1,375,000 | $54.5M | 3.64% | −235,000−14.6% | Reduced |
| Darwin Global Management, Ltd. | 1,982,016 | $78.6M | 10.46% | +1,982,016 | New |
| Paradigm Biocapital Advisors LP | 2,121,163 | $84.1M | 2.96% | −1,055,580−33.2% | Reduced |
| Lynx1 Capital Management LP | 2,253,183 | $89.3M | 23.00% | −1,560,743−40.9% | Reduced |
| OrbiMed Advisors LLC | 2,680,496 | $106.3M | 2.08% | +145,251+5.7% | Added |
| Cormorant Asset Management, LP | 2,700,000 | $107.0M | 4.72% | +150,000+5.9% | Added |
| Vanguard Group Inc | 2,712,285 | $107.5M | 0.00% | +477,518+21.4% | Added |
| State Street Corp | 2,845,839 | $112.8M | 0.01% | +1,455,810+104.7% | Added |
| Price T Rowe Associates Inc | 3,080,220 | $122.1M | 0.01% | +1,392,942+82.6% | Added |
| Frazier Life Sciences Management, L.P. | 3,131,008 | $124.1M | 5.24% | 00.0% | Unchanged |
| BlackRock Inc. | 3,575,092 | $141.7M | 0.00% | +516,594+16.9% | Added |
| Avoro Capital Advisors LLC | 5,775,000 | $228.9M | 2.67% | +5,775,000 | New |
| Decheng Capital LLC | 8,317,924 | $329.7M | 44.22% | +1,234,636+17.4% | Added |
| Ra Capital Management, L.P. | 0 | $0 | 0.00% | −4,909,763−100.0% | Sold out |
| Ally Bridge Group (NY) LLC | 0 | $0 | 0.00% | −357,271−100.0% | Sold out |
| StemPoint Capital LP | 0 | $0 | 0.00% | −246,178−100.0% | Sold out |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −221,118−100.0% | Sold out |
| Hudson Bay Capital Management LP | 0 | $0 | 0.00% | −197,019−100.0% | Sold out |
| Laurion Capital Management LP | 0 | $0 | 0.00% | −97,200−100.0% | Sold out |
| Ghisallo Capital Management LLC | 0 | $0 | 0.00% | −65,000−100.0% | Sold out |
| Jump Financial, LLC | 0 | $0 | 0.00% | −55,720−100.0% | Sold out |
| Cubist Systematic Strategies, LLC | 0 | $0 | 0.00% | −48,670−100.0% | Sold out |
| Walleye Trading LLC | 0 | $0 | 0.00% | −25,596−100.0% | Sold out |
| Occudo Quantitative Strategies LP | 0 | $0 | 0.00% | −25,554−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −21,878−100.0% | Sold out |
| Corton Capital Inc. | 0 | $0 | 0.00% | −16,934−100.0% | Sold out |
| Point72 Middle East FZE | 0 | $0 | 0.00% | −7,900−100.0% | Sold out |
| AJOVista, LLC | 0 | $0 | 0.00% | −3,371−100.0% | Sold out |
| ADAR1 Capital Management, LLC | 0 | $0 | 0.00% | −3,027−100.0% | Sold out |