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Alpine Immune Sciences, Inc.

ALPNDelisted May 20, 2024
Industry
Pharmaceutical Preparations
SEC CIK
0001626199

Alpine Immune Sciences, Inc. was delisted on May 20, 2024; its insiders filed their last Form 4 on May 20, 2024; 180 institutions reported holding it in 13F filings for Q1 2024, worth $2.56B in total; no superinvestor held it.

13F holders, Q3 2023

Institutional positions in Alpine Immune Sciences, Inc. as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
88
+11 vs. Q2 2023
Shares held
45.9M
+2.22M (+5.1%) vs. Q2 2023
Total value
$525.8M
+$76.6M (+17.0%) vs. Q2 2023
New holders
16
34 more added
Sold out
5
21 more reduced

Compare with Q2 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALPN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2023: 88 institutions
Q1 2021: 48 institutionsQ2 2021: 47 institutionsQ3 2021: 44 institutionsQ4 2021: 53 institutionsQ1 2022: 56 institutionsQ2 2022: 58 institutionsQ3 2022: 70 institutionsQ4 2022: 64 institutionsQ1 2023: 61 institutionsQ2 2023: 77 institutionsQ3 2023: 88 institutionsQ4 2023: 133 institutionsQ1 2024: 180 institutionsQ2 2024: 0 institutionsQ3 2024: 0 institutionsQ4 2024: 0 institutionsQ1 2025: 0 institutionsQ2 2025: 0 institutionsQ3 2025: 0 institutionsQ4 2025: 0 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ3 2023: $525.8M
Q1 2021: $145.0MQ2 2021: $118.5MQ3 2021: $163.5MQ4 2021: $257.1MQ1 2022: $221.8MQ2 2022: $204.4MQ3 2022: $284.0MQ4 2022: $300.8MQ1 2023: $319.4MQ2 2023: $449.3MQ3 2023: $525.8MQ4 2023: $1.12BQ1 2024: $2.56BQ2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: $0Q2 2025: $0Q3 2025: $0Q4 2025: $0Q1 2026: $0Q2 2026: $0
Institutions holding ALPN and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20250$0
Q3 20250$0
Q2 20250$0
Q1 20250$0
Q4 20240$0
Q3 20240$0
Q2 20240$0
Q1 2024180$2.56B
Q4 2023133$1.12B
Q3 202388$525.8M
Q2 202377$449.3M
Q1 202361$319.4M
Q4 202264$300.8M
Q3 202270$284.0M
Q2 202258$204.4M
Q1 202256$221.8M
Q4 202153$257.1M
Q3 202144$163.5M
Q2 202147$118.5M
Q1 202148$145.0M

Institutions, Q3 2023

Shares, value and share of portfolio for each institution holding Alpine Immune Sciences, Inc.; share changes are against Q2 2023.

Institutions holding ALPN in Q3 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Decheng Capital Management III (Cayman), LLC6,708,288$76.8M25.63%00.0%Unchanged
Ra Capital Management, L.P.4,691,178$53.7M1.06%00.0%Unchanged
OrbiMed Advisors LLC4,081,592$46.7M1.08%00.0%Unchanged
Great Point Partners LLC3,078,633$35.3M6.63%−285,055−8.5%Reduced
Frazier Life Sciences Management, L.P.2,985,757$34.2M2.27%00.0%Unchanged
Paradigm Biocapital Advisors LP2,421,743$27.7M1.89%−2,218−0.1%Reduced
Lynx1 Capital Management LP2,404,614$27.5M18.21%−265,858−10.0%Reduced
BlackRock Inc.2,351,917$26.9M0.00%+70,225+3.1%Added
Cormorant Asset Management, LP1,900,000$21.8M1.27%+1,900,000New
Vanguard Group Inc1,474,879$16.9M0.00%+70,912+5.1%Added
Price T Rowe Associates Inc1,396,444$16.0M0.00%+1,374,704+6,323.4%Added
Commodore Capital LP1,325,000$15.2M1.77%00.0%Unchanged
Artal Group S.A.1,193,030$13.7M0.60%00.0%Unchanged
Woodline Partners LP1,038,777$11.9M0.14%+801,213+337.3%Added
Vivo Capital, LLC914,913$10.5M1.30%00.0%Unchanged
Octagon Capital Advisors LP750,000$8.59M1.51%00.0%Unchanged
Ghost Tree Capital, LLC664,132$7.60M3.68%+316,700+91.2%Added
Avidity Partners Management LP657,280$7.53M0.30%−401,220−37.9%Reduced
Geode Capital Management, LLC628,925$7.20M0.00%+10,951+1.8%Added
State Street Corp605,545$6.93M0.00%+32,703+5.7%Added
FMR LLC464,812$5.32M0.00%−210,774−31.2%Reduced
Tri Locum Partners LP314,029$3.60M1.15%−17,963−5.4%Reduced
Renaissance Technologies LLC288,194$3.30M0.01%−31,100−9.7%Reduced
Northern Trust Corp270,424$3.10M0.00%+12,900+5.0%Added
Two Sigma Advisers, LP246,075$2.82M0.01%+159,700+184.9%Added
Charles Schwab Investment Management Inc234,256$2.68M0.00%+147,976+171.5%Added
Invesco Ltd.217,136$2.49M0.00%+217,136New
ExodusPoint Capital Management, LP217,055$2.48M0.03%+154,216+245.4%Added
Two Sigma Investments, LP190,589$2.18M0.01%+132,561+228.4%Added
Walleye Capital LLC186,273$2.13M0.03%+21,600+13.1%Added
Nan Fung Group Holdings Ltd182,280$2.09M1.69%+182,280New
Sphera Funds Management Ltd.180,000$2.06M0.49%−20,000−10.0%Reduced
Dimensional Fund Advisors LP167,308$1.92M0.00%+25,809+18.2%Added
Omega Fund Management, LLC153,700$1.76M1.62%−1,875,880−92.4%Reduced
Nuveen Asset Management, LLC93,385$1.07M0.00%−292−0.3%Reduced
Bank of New York Mellon Corp92,723$1.06M0.00%+1,216+1.3%Added
Schonfeld Strategic Advisors LLC90,937$1.04M0.01%+78,037+604.9%Added
Soleus Capital Management, L.P.88,073$1.01M0.10%00.0%Unchanged
Millennium Management LLC82,926$949.5K0.00%−33,249−28.6%Reduced
Goldman Sachs Group Inc66,445$760.8K0.00%+10,670+19.1%Added
Morgan Stanley53,473$612.3K0.00%+3,269+6.5%Added
D. E. Shaw & Co., Inc.48,631$556.8K0.00%+48,631New
Connor, Clark & Lunn Investment Management Ltd.45,475$520.7K0.00%−1,118−2.4%Reduced
Swiss National Bank42,200$483.2K0.00%+42,200New
Rhumbline Advisers41,403$474.1K0.00%+1,977+5.0%Added
HighVista Strategies LLC39,861$456.4K0.21%−50,426−55.9%Reduced
Wellington Management Group LLP39,731$454.9K0.00%+39,731New
JPMorgan Chase & Co31,309$358.5K0.00%+4,960+18.8%Added
Trexquant Investment LP28,578$327.2K0.01%−14,195−33.2%Reduced
Manufacturers Life Insurance Company, The28,383$325.0K0.00%+14,900+110.5%Added
Citadel Advisors LLC28,174$322.6K0.00%−25,549−47.6%Reduced
California State Teachers Retirement System23,993$274.7K0.00%+13,434+127.2%Added
Legal & General Group Plc22,715$260.1K0.00%+19,223+550.5%Added
State of Wisconsin Investment Board22,197$254.2K0.00%+22,197New
Bank of America Corp21,300$243.9K0.00%+3,385+18.9%Added
Algert Global LLC20,010$229.1K0.01%+20,010New
UBS Group AG19,047$218.1K0.00%−26,803−58.5%Reduced
Driehaus Capital Management LLC18,636$213.4K0.00%+18,636New
Alliancebernstein L.P.18,500$211.8K0.00%+2,680+16.9%Added
Jane Street Group, LLC18,198$208.4K0.00%+18,198New
Deutsche Bank AG17,511$200.5K0.00%−109,814−86.2%Reduced
Mirae Asset Global Investments Co., Ltd.17,153$196.4K0.00%+72+0.4%Added
MetLife Investment Management16,818$192.6K0.00%00.0%Unchanged
American International Group, Inc.15,842$181.4K0.00%+563+3.7%Added
Credit Suisse AG15,209$174.1K0.00%+15,209New
Moore Capital Management, LP13,744$157.4K0.00%−100−0.7%Reduced
BNP Paribas Arbitrage, SA13,518$154.8K0.00%+5,029+59.2%Added
Voya Investment Management LLC13,502$154.6K0.00%+366+2.8%Added
Hikari Power Ltd12,445$142.0K0.01%00.0%Unchanged
Western Wealth Management, LLC12,000$137.4K0.01%00.0%Unchanged
Qube Research & Technologies Ltd10,070$115.3K0.00%+10,070New
SG Americas Securities, LLC9,927$114.0K0.00%+9,927New
New York State Common Retirement Fund9,634$110.3K0.00%+4,155+75.8%Added
Barclays PLC9,126$104.5K0.00%+2,801+44.3%Added
Wells Fargo & Company7,035$80.6K0.00%−5,646−44.5%Reduced
Royal Bank of Canada6,323$72.0K0.00%+3,681+139.3%Added
Amalgamated Bank3,656$42.0K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.2,621$30.0K0.00%00.0%Unchanged
Dorsey Wright & Associates2,273$26.0K0.01%−78−3.3%Reduced
Metropolitan Life Insurance Co1,743$20.0K0.00%00.0%Unchanged
China Universal Asset Management Co., Ltd.1,269$14.5K0.00%+640+101.7%Added
Tower Research Capital LLC (TRC)1,073$12.3K0.00%+40+3.9%Added
Citigroup Inc670$7.67K0.00%−9,606−93.5%Reduced
Allspring Global Investments Holdings, LLC176$2.02K0.00%+176New
Aquatic Capital Management LLC200$2.00K0.00%+200New
GWM Advisors LLC125$1.43K0.00%+125New
Daiwa Securities Group Inc.85$1.00K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC12$1370.00%00.0%Unchanged
TCG Crossover Management, LLC0$00.00%−253,069−100.0%Sold out
Affinity Asset Advisors, LLC0$00.00%−118,891−100.0%Sold out
Westwood Holdings Group Inc.0$00.00%−43,799−100.0%Sold out
Panagora Asset Management Inc0$00.00%−12,394−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−11,451−100.0%Sold out