Alpine Immune Sciences, Inc.
ALPNDelisted May 20, 2024- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001626199
Alpine Immune Sciences, Inc. was delisted on May 20, 2024; its insiders filed their last Form 4 on May 20, 2024; 180 institutions reported holding it in 13F filings for Q1 2024, worth $2.56B in total; no superinvestor held it.
13F holders, Q4 2021
Institutional positions in Alpine Immune Sciences, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 53
- +9 vs. Q3 2021
- Shares held
- 18.6M
- +3.24M (+21.1%) vs. Q3 2021
- Total value
- $257.1M
- +$93.6M (+57.2%) vs. Q3 2021
- New holders
- 13
- 21 more added
- Sold out
- 4
- 9 more reduced
Compare with Q3 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ALPN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 0 | $0 |
| Q1 2026 | 0 | $0 |
| Q4 2025 | 0 | $0 |
| Q3 2025 | 0 | $0 |
| Q2 2025 | 0 | $0 |
| Q1 2025 | 0 | $0 |
| Q4 2024 | 0 | $0 |
| Q3 2024 | 0 | $0 |
| Q2 2024 | 0 | $0 |
| Q1 2024 | 180 | $2.56B |
| Q4 2023 | 133 | $1.12B |
| Q3 2023 | 88 | $525.8M |
| Q2 2023 | 77 | $449.3M |
| Q1 2023 | 61 | $319.4M |
| Q4 2022 | 64 | $300.8M |
| Q3 2022 | 70 | $284.0M |
| Q2 2022 | 58 | $204.4M |
| Q1 2022 | 56 | $221.8M |
| Q4 2021 | 53 | $257.1M |
| Q3 2021 | 44 | $163.5M |
| Q2 2021 | 47 | $118.5M |
| Q1 2021 | 48 | $145.0M |
Institutions, Q4 2021
Shares, value and share of portfolio for each institution holding Alpine Immune Sciences, Inc.; share changes are against Q3 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| OrbiMed Advisors LLC | 4,081,592 | $56.5M | 0.73% | 00.0% | Unchanged |
| Omega Fund Management, LLC | 2,029,580 | $28.1M | 3.97% | 00.0% | Unchanged |
| Frazier Management LLC | 1,784,913 | $24.7M | 1.90% | +13,069+0.7% | Added |
| BVF Inc | 1,589,495 | $22.0M | 0.80% | 00.0% | Unchanged |
| Avidity Partners Management LP | 1,345,000 | $18.6M | 0.40% | −587,000−30.4% | Reduced |
| Lynx1 Capital Management LP | 1,261,927 | $17.5M | 15.25% | +1,261,927 | New |
| TCG Crossover Management, LLC | 1,170,212 | $16.2M | 7.59% | +1,170,212 | New |
| Logos Global Management LP | 1,120,000 | $15.5M | 1.60% | +695,000+163.5% | Added |
| BlackRock Inc. | 728,848 | $10.1M | 0.00% | +181,066+33.1% | Added |
| Vanguard Group Inc | 697,754 | $9.66M | 0.00% | +117,276+20.2% | Added |
| Artal Group S.A. | 593,030 | $8.21M | 0.24% | 00.0% | Unchanged |
| Renaissance Technologies LLC | 386,294 | $5.35M | 0.01% | −9,300−2.4% | Reduced |
| Acuta Capital Partners, LLC | 230,000 | $3.19M | 1.34% | +230,000 | New |
| State Street Corp | 206,012 | $2.85M | 0.00% | +8,216+4.2% | Added |
| Geode Capital Management, LLC | 196,666 | $2.72M | 0.00% | +2,645+1.4% | Added |
| Bridgeway Capital Management, LLC | 145,611 | $2.02M | 0.04% | −8,000−5.2% | Reduced |
| Tiger Management L.L.C. | 137,728 | $1.91M | 0.38% | 00.0% | Unchanged |
| Walleye Capital LLC | 110,099 | $1.52M | 0.05% | +110,099 | New |
| Two Sigma Advisers, LP | 107,775 | $1.49M | 0.00% | +66,100+158.6% | Added |
| Northern Trust Corp | 105,595 | $1.46M | 0.00% | −1,639−1.5% | Reduced |
| Two Sigma Investments, LP | 79,682 | $1.10M | 0.00% | +40,464+103.2% | Added |
| Ensign Peak Advisors, Inc | 72,930 | $1.01M | 0.00% | 00.0% | Unchanged |
| Dimensional Fund Advisors LP | 53,064 | $735.0K | 0.00% | +2,700+5.4% | Added |
| Bank of New York Mellon Corp | 51,745 | $716.0K | 0.00% | +1,207+2.4% | Added |
| Alps Advisors Inc | 33,815 | $468.0K | 0.01% | +4,511+15.4% | Added |
| Charles Schwab Investment Management Inc | 30,123 | $418.0K | 0.00% | +5,500+22.3% | Added |
| Westwood Holdings Group Inc. | 23,079 | $319.0K | 0.00% | +23,079 | New |
| Connor, Clark & Lunn Investment Management Ltd. | 19,026 | $264.0K | 0.00% | +19,026 | New |
| Nuveen Asset Management, LLC | 18,446 | $218.0K | 0.00% | 00.0% | Unchanged |
| Barclays PLC | 14,098 | $196.0K | 0.00% | +9,351+197.0% | Added |
| Goldman Sachs Group Inc | 13,379 | $185.0K | 0.00% | +13,379 | New |
| Jump Financial, LLC | 12,600 | $175.0K | 0.01% | +12,600 | New |
| Western Wealth Management, LLC | 12,360 | $171.0K | 0.02% | +12,360 | New |
| Parametric Portfolio Associates LLC | 10,875 | $151.0K | 0.00% | +10,875 | New |
| Hikari Power Ltd | 10,445 | $145.0K | 0.01% | 00.0% | Unchanged |
| Wells Fargo & Company | 9,438 | $130.0K | 0.00% | −45,440−82.8% | Reduced |
| Morgan Stanley | 9,145 | $127.0K | 0.00% | +6,411+234.5% | Added |
| JPMorgan Chase & Co | 7,250 | $101.0K | 0.00% | +2,790+62.6% | Added |
| Deutsche Bank AG | 7,042 | $98.0K | 0.00% | +362+5.4% | Added |
| American International Group, Inc. | 6,173 | $85.0K | 0.00% | −185−2.9% | Reduced |
| California State Teachers Retirement System | 6,150 | $85.0K | 0.00% | −65−1.0% | Reduced |
| Allspring Global Investments Holdings, LLC | 6,027 | $83.0K | 0.00% | +6,027 | New |
| STRS Ohio | 5,500 | $76.0K | 0.00% | +5,500 | New |
| New York State Common Retirement Fund | 5,397 | $75.0K | 0.00% | −20−0.4% | Reduced |
| UBS Group AG | 4,996 | $70.0K | 0.00% | +3,854+337.5% | Added |
| Bank of America Corp | 4,944 | $69.0K | 0.00% | +1,573+46.7% | Added |
| Citigroup Inc | 3,766 | $52.0K | 0.00% | +2,440+184.0% | Added |
| BNP Paribas Arbitrage, SA | 3,246 | $45.0K | 0.00% | +1,130+53.4% | Added |
| Royal Bank of Canada | 2,612 | $36.0K | 0.00% | +1,429+120.8% | Added |
| Legal & General Group Plc | 1,227 | $17.0K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 911 | $13.0K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 805 | $11.0K | 0.00% | −1,183−59.5% | Reduced |
| Daiwa Securities Group Inc. | 85 | $1.00K | 0.00% | +85 | New |
| DAFNA Capital Management LLC | 0 | $0 | 0.00% | −111,501−100.0% | Sold out |
| Leonard Rickey Investment Advisors P.L.L.C. | 0 | $0 | 0.00% | −17,013−100.0% | Sold out |
| HighVista Strategies LLC | 0 | $0 | 0.00% | −14,268−100.0% | Sold out |
| EcoR1 Capital, LLC | 0 | $0 | 0.00% | −7,001−100.0% | Sold out |