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Alpine Immune Sciences, Inc.

ALPNDelisted May 20, 2024
Industry
Pharmaceutical Preparations
SEC CIK
0001626199

Alpine Immune Sciences, Inc. was delisted on May 20, 2024; its insiders filed their last Form 4 on May 20, 2024; 180 institutions reported holding it in 13F filings for Q1 2024, worth $2.56B in total; no superinvestor held it.

13F holders, Q2 2023

Institutional positions in Alpine Immune Sciences, Inc. as of Jun 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
77
+16 vs. Q1 2023
Shares held
43.7M
+2.33M (+5.6%) vs. Q1 2023
Total value
$449.3M
+$129.8M (+40.6%) vs. Q1 2023
New holders
18
34 more added
Sold out
2
12 more reduced

Compare with Q1 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALPN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2023: 77 institutions
Q1 2021: 48 institutionsQ2 2021: 47 institutionsQ3 2021: 44 institutionsQ4 2021: 53 institutionsQ1 2022: 56 institutionsQ2 2022: 58 institutionsQ3 2022: 70 institutionsQ4 2022: 64 institutionsQ1 2023: 61 institutionsQ2 2023: 77 institutionsQ3 2023: 88 institutionsQ4 2023: 133 institutionsQ1 2024: 180 institutionsQ2 2024: 0 institutionsQ3 2024: 0 institutionsQ4 2024: 0 institutionsQ1 2025: 0 institutionsQ2 2025: 0 institutionsQ3 2025: 0 institutionsQ4 2025: 0 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ2 2023: $449.3M
Q1 2021: $145.0MQ2 2021: $118.5MQ3 2021: $163.5MQ4 2021: $257.1MQ1 2022: $221.8MQ2 2022: $204.4MQ3 2022: $284.0MQ4 2022: $300.8MQ1 2023: $319.4MQ2 2023: $449.3MQ3 2023: $525.8MQ4 2023: $1.12BQ1 2024: $2.56BQ2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: $0Q2 2025: $0Q3 2025: $0Q4 2025: $0Q1 2026: $0Q2 2026: $0
Institutions holding ALPN and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20250$0
Q3 20250$0
Q2 20250$0
Q1 20250$0
Q4 20240$0
Q3 20240$0
Q2 20240$0
Q1 2024180$2.56B
Q4 2023133$1.12B
Q3 202388$525.8M
Q2 202377$449.3M
Q1 202361$319.4M
Q4 202264$300.8M
Q3 202270$284.0M
Q2 202258$204.4M
Q1 202256$221.8M
Q4 202153$257.1M
Q3 202144$163.5M
Q2 202147$118.5M
Q1 202148$145.0M

Institutions, Q2 2023

Shares, value and share of portfolio for each institution holding Alpine Immune Sciences, Inc.; share changes are against Q1 2023.

Institutions holding ALPN in Q2 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Decheng Capital Management III (Cayman), LLC6,708,288$69.0M21.63%00.0%Unchanged
Ra Capital Management, L.P.4,691,178$48.2M0.91%+3,063+0.1%Added
OrbiMed Advisors LLC4,081,592$42.0M0.82%00.0%Unchanged
Great Point Partners LLC3,363,688$34.6M6.93%−377,073−10.1%Reduced
Frazier Life Sciences Management, L.P.2,985,757$30.7M1.83%00.0%Unchanged
Lynx1 Capital Management LP2,670,472$27.5M17.99%−465,701−14.8%Reduced
Paradigm Biocapital Advisors LP2,423,961$24.9M2.02%+106,327+4.6%Added
BlackRock Inc.2,281,692$23.5M0.00%+728,772+46.9%Added
Omega Fund Management, LLC2,029,580$20.9M11.69%00.0%Unchanged
Vanguard Group Inc1,403,967$14.4M0.00%+34,258+2.5%Added
Commodore Capital LP1,325,000$13.6M1.53%00.0%Unchanged
Artal Group S.A.1,193,030$12.3M0.39%00.0%Unchanged
Avidity Partners Management LP1,058,500$10.9M0.38%+69,000+7.0%Added
Vivo Capital, LLC914,913$9.41M1.13%+914,913New
Octagon Capital Advisors LP750,000$7.71M1.08%−452,000−37.6%Reduced
FMR LLC675,586$6.95M0.00%+674,330+53,688.7%Added
Geode Capital Management, LLC617,974$6.35M0.00%+61,767+11.1%Added
State Street Corp572,842$5.89M0.00%+226,171+65.2%Added
Ghost Tree Capital, LLC347,432$3.57M1.29%+147,432+73.7%Added
Tri Locum Partners LP331,992$3.41M1.27%+331,992New
Renaissance Technologies LLC319,294$3.28M0.00%−11,000−3.3%Reduced
Northern Trust Corp257,524$2.65M0.00%+63,537+32.8%Added
TCG Crossover Management, LLC253,069$2.60M0.43%00.0%Unchanged
Woodline Partners LP237,564$2.44M0.03%+237,564New
Sphera Funds Management Ltd.200,000$2.06M0.44%00.0%Unchanged
Walleye Capital LLC164,673$1.69M0.03%+130,556+382.7%Added
Dimensional Fund Advisors LP141,499$1.45M0.00%+1,827+1.3%Added
Deutsche Bank AG127,325$1.31M0.00%+112,574+763.2%Added
Affinity Asset Advisors, LLC118,891$1.22M0.48%−129,000−52.0%Reduced
Millennium Management LLC116,175$1.19M0.00%+116,175New
Nuveen Asset Management, LLC93,677$963.0K0.00%+61,948+195.2%Added
Bank of New York Mellon Corp91,507$940.7K0.00%+19,701+27.4%Added
HighVista Strategies LLC90,287$928.1K0.42%00.0%Unchanged
Soleus Capital Management, L.P.88,073$905.4K0.10%+88,073New
Two Sigma Advisers, LP86,375$887.9K0.00%+45,400+110.8%Added
Charles Schwab Investment Management Inc86,280$887.0K0.00%+19,014+28.3%Added
ExodusPoint Capital Management, LP62,839$646.0K0.01%+62,839New
Two Sigma Investments, LP58,028$596.5K0.00%+58,028New
Goldman Sachs Group Inc55,775$573.4K0.00%+24,918+80.8%Added
Citadel Advisors LLC53,723$552.3K0.00%+53,723New
Morgan Stanley50,204$516.1K0.00%+22,290+79.9%Added
Connor, Clark & Lunn Investment Management Ltd.46,593$479.0K0.00%−7,644−14.1%Reduced
UBS Group AG45,850$471.3K0.00%+37,857+473.6%Added
Westwood Holdings Group Inc.43,799$450.0K0.00%+43,799New
Trexquant Investment LP42,773$439.7K0.01%+42,773New
Rhumbline Advisers39,426$405.3K0.00%+6,578+20.0%Added
JPMorgan Chase & Co26,349$270.9K0.00%−21,800−45.3%Reduced
Price T Rowe Associates Inc21,740$224.0K0.00%+2,115+10.8%Added
Bank of America Corp17,915$184.2K0.00%−5,585−23.8%Reduced
Mirae Asset Global Investments Co., Ltd.17,081$175.6K0.00%+17,081New
MetLife Investment Management16,818$172.9K0.00%+4,790+39.8%Added
Alliancebernstein L.P.15,820$162.6K0.00%+15,820New
American International Group, Inc.15,279$157.1K0.00%+3,861+33.8%Added
Moore Capital Management, LP13,844$142.3K0.00%+13,844New
Manufacturers Life Insurance Company, The13,483$138.6K0.00%+13,483New
Voya Investment Management LLC13,136$135.0K0.00%+13,136New
Schonfeld Strategic Advisors LLC12,900$132.6K0.00%+12,900New
Wells Fargo & Company12,681$130.4K0.00%+8,289+188.7%Added
Hikari Power Ltd12,445$128.0K0.01%00.0%Unchanged
Panagora Asset Management Inc12,394$127.4K0.00%+12,394New
Western Wealth Management, LLC12,000$123.4K0.01%00.0%Unchanged
Susquehanna International Group, LLP11,451$117.7K0.00%+817+7.7%Added
California State Teachers Retirement System10,559$108.5K0.00%+1,763+20.0%Added
Citigroup Inc10,276$105.6K0.00%+9,753+1,864.8%Added
BNP Paribas Arbitrage, SA8,489$87.3K0.00%−12,029−58.6%Reduced
Barclays PLC6,325$65.0K0.00%−5,754−47.6%Reduced
New York State Common Retirement Fund5,479$56.3K0.00%−26−0.5%Reduced
Amalgamated Bank3,656$38.0K0.00%+823+29.1%Added
Legal & General Group Plc3,492$35.9K0.00%+1,019+41.2%Added
Royal Bank of Canada2,642$27.0K0.00%+1,315+99.1%Added
Ameritas Investment Partners, Inc.2,621$26.9K0.00%+721+37.9%Added
Dorsey Wright & Associates2,351$24.2K0.01%+2,351New
Metropolitan Life Insurance Co1,743$17.9K0.00%+1,206+224.6%Added
Tower Research Capital LLC (TRC)1,033$10.6K0.00%−466−31.1%Reduced
China Universal Asset Management Co., Ltd.629$6.47K0.00%+6+1.0%Added
Daiwa Securities Group Inc.85$1.00K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC12$1230.00%00.0%Unchanged
BVF Inc0$00.00%−858,339−100.0%Sold out
SG Americas Securities, LLC0$00.00%−11,927−100.0%Sold out