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Alpine Immune Sciences, Inc.

ALPNDelisted May 20, 2024
Industry
Pharmaceutical Preparations
SEC CIK
0001626199

Alpine Immune Sciences, Inc. was delisted on May 20, 2024; its insiders filed their last Form 4 on May 20, 2024; 180 institutions reported holding it in 13F filings for Q1 2024, worth $2.56B in total; no superinvestor held it.

13F holders, Q2 2022

Institutional positions in Alpine Immune Sciences, Inc. as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
58
+3 vs. Q1 2022
Shares held
24.0M
−713.6K (−2.9%) vs. Q1 2022
Total value
$204.4M
−$17.4M (−7.9%) vs. Q1 2022
New holders
9
22 more added
Sold out
6
17 more reduced

1 institution that held it in Q1 2022 haven't filed for Q2 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALPN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2022: 58 institutions
Q1 2021: 48 institutionsQ2 2021: 47 institutionsQ3 2021: 44 institutionsQ4 2021: 53 institutionsQ1 2022: 56 institutionsQ2 2022: 58 institutionsQ3 2022: 70 institutionsQ4 2022: 64 institutionsQ1 2023: 61 institutionsQ2 2023: 77 institutionsQ3 2023: 88 institutionsQ4 2023: 133 institutionsQ1 2024: 180 institutionsQ2 2024: 0 institutionsQ3 2024: 0 institutionsQ4 2024: 0 institutionsQ1 2025: 0 institutionsQ2 2025: 0 institutionsQ3 2025: 0 institutionsQ4 2025: 0 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ2 2022: $204.4M
Q1 2021: $145.0MQ2 2021: $118.5MQ3 2021: $163.5MQ4 2021: $257.1MQ1 2022: $221.8MQ2 2022: $204.4MQ3 2022: $284.0MQ4 2022: $300.8MQ1 2023: $319.4MQ2 2023: $449.3MQ3 2023: $525.8MQ4 2023: $1.12BQ1 2024: $2.56BQ2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: $0Q2 2025: $0Q3 2025: $0Q4 2025: $0Q1 2026: $0Q2 2026: $0
Institutions holding ALPN and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20250$0
Q3 20250$0
Q2 20250$0
Q1 20250$0
Q4 20240$0
Q3 20240$0
Q2 20240$0
Q1 2024180$2.56B
Q4 2023133$1.12B
Q3 202388$525.8M
Q2 202377$449.3M
Q1 202361$319.4M
Q4 202264$300.8M
Q3 202270$284.0M
Q2 202258$204.4M
Q1 202256$221.8M
Q4 202153$257.1M
Q3 202144$163.5M
Q2 202147$118.5M
Q1 202148$145.0M

Institutions, Q2 2022

Shares, value and share of portfolio for each institution holding Alpine Immune Sciences, Inc.; share changes are against Q1 2022.

Institutions holding ALPN in Q2 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Decheng Capital Management III (Cayman), LLC4,708,288$40.1M15.19%00.0%Unchanged
OrbiMed Advisors LLC4,081,592$34.7M0.67%00.0%Unchanged
Frazier Life Sciences Management, L.P.2,985,757$25.4M2.40%−1,200,000−28.7%Reduced
Omega Fund Management, LLC2,029,580$17.3M5.51%00.0%Unchanged
Lynx1 Capital Management LP1,926,869$16.4M13.97%+442,176+29.8%Added
BVF Inc1,275,240$10.9M0.52%−314,255−19.8%Reduced
Avidity Partners Management LP998,565$8.50M0.20%−208,435−17.3%Reduced
BlackRock Inc.878,368$7.48M0.00%+155,230+21.5%Added
Paradigm Biocapital Advisors LP826,779$7.04M1.40%+490,550+145.9%Added
Vanguard Group Inc629,773$5.36M0.00%−77,825−11.0%Reduced
Artal Group S.A.593,030$5.05M0.28%00.0%Unchanged
TCG Crossover Management, LLC578,260$4.92M2.09%−455,962−44.1%Reduced
Great Point Partners LLC538,819$4.58M1.18%+538,819New
Renaissance Technologies LLC397,394$3.38M0.00%+11,300+2.9%Added
State Street Corp268,082$2.28M0.00%+47,461+21.5%Added
Geode Capital Management, LLC247,992$2.11M0.00%+32,836+15.3%Added
Allspring Global Investments Holdings, LLC136,797$1.16M0.00%+119,935+711.3%Added
Northern Trust Corp125,774$1.07M0.00%+24,066+23.7%Added
Two Sigma Advisers, LP101,575$864.0K0.00%−12,600−11.0%Reduced
Bridgeway Capital Management, LLC95,611$814.0K0.02%−50,000−34.3%Reduced
Bank of New York Mellon Corp58,554$499.0K0.00%+9,399+19.1%Added
Dimensional Fund Advisors LP51,370$437.0K0.00%−1,694−3.2%Reduced
Western Standard LLC50,328$428.0K0.32%+50,328New
Connor, Clark & Lunn Investment Management Ltd.50,189$427.0K0.00%+21,873+77.2%Added
Alberta Investment Management Corp45,906$391.0K0.00%+45,906New
Goldman Sachs Group Inc42,916$365.0K0.00%+20,066+87.8%Added
Charles Schwab Investment Management Inc39,823$339.0K0.00%+7,406+22.8%Added
Marshall Wace, LLP35,930$305.0K0.00%+35,930New
Western Wealth Management, LLC25,120$214.0K0.01%+25,120New
Tower Research Capital LLC (TRC)21,209$180.0K0.00%+19,205+958.3%Added
Rhumbline Advisers20,404$174.0K0.00%+20,404New
Two Sigma Investments, LP20,030$170.0K0.00%−27,678−58.0%Reduced
Nuveen Asset Management, LLC18,446$157.0K0.00%00.0%Unchanged
Susquehanna International Group, LLP14,121$120.0K0.00%+1,700+13.7%Added
Morgan Stanley13,199$112.0K0.00%+3,922+42.3%Added
Hikari Power Ltd12,445$106.0K0.01%00.0%Unchanged
Bank of America Corp9,875$85.0K0.00%−5,567−36.1%Reduced
JPMorgan Chase & Co9,669$82.0K0.00%+722+8.1%Added
Deutsche Bank AG9,089$77.0K0.00%+2,789+44.3%Added
American International Group, Inc.7,310$62.0K0.00%+1,543+26.8%Added
California State Teachers Retirement System6,679$57.0K0.00%+1,712+34.5%Added
STRS Ohio5,500$46.0K0.00%00.0%Unchanged
New York State Common Retirement Fund5,397$46.0K0.00%00.0%Unchanged
Lazard Asset Management LLC4,617$39.0K0.00%+4,617New
BNP Paribas Arbitrage, SA3,482$29.6K0.00%−295−7.8%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)2,045$17.0K0.00%−212−9.4%Reduced
Amalgamated Bank2,014$17.0K0.00%+123+6.5%Added
Citigroup Inc1,597$14.0K0.00%+554+53.1%Added
Legal & General Group Plc1,442$12.0K0.00%+215+17.5%Added
UBS Group AG1,200$10.0K0.00%−1,169−49.3%Reduced
Barclays PLC783$7.00K0.00%−1,103−58.5%Reduced
Ameritas Investment Partners, Inc.911$7.00K0.00%00.0%Unchanged
Simplex Trading, LLC396$3.00K0.00%+396New
Wells Fargo & Company290$2.00K0.00%−5,413−94.9%Reduced
Royal Bank of Canada88$1.00K0.00%−625−87.7%Reduced
FMR LLC134$1.00K0.00%−132−49.6%Reduced
Daiwa Securities Group Inc.85$1.00K0.00%00.0%Unchanged
Credit Suisse AG15$00.00%+15New
Jacobs Levy Equity Management, Inc0$00.00%−138,279−100.0%Sold out
Tiger Management L.L.C.0$00.00%−137,728−100.0%Sold out
Ensign Peak Advisors, Inc0$00.00%−110,017−100.0%Sold out
Walleye Capital LLC0$00.00%−41,746−100.0%Sold out
Alps Advisors Inc0$00.00%−30,030−100.0%Sold out
Kingsbury Capital Investment Advisors LLC0$00.00%−29,153−100.0%Sold out
Amalgamated Financial Corp.––––Not filed