Skip to main content

Alpine Immune Sciences, Inc.

ALPNDelisted May 20, 2024
Industry
Pharmaceutical Preparations
SEC CIK
0001626199

Alpine Immune Sciences, Inc. was delisted on May 20, 2024; its insiders filed their last Form 4 on May 20, 2024; 180 institutions reported holding it in 13F filings for Q1 2024, worth $2.56B in total; no superinvestor held it.

13F holders, Q3 2022

Institutional positions in Alpine Immune Sciences, Inc. as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
70
+12 vs. Q2 2022
Shares held
39.5M
+15.4M (+64.3%) vs. Q2 2022
Total value
$284.0M
+$79.7M (+39.0%) vs. Q2 2022
New holders
16
24 more added
Sold out
4
18 more reduced

Compare with Q2 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALPN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2022: 70 institutions
Q1 2021: 48 institutionsQ2 2021: 47 institutionsQ3 2021: 44 institutionsQ4 2021: 53 institutionsQ1 2022: 56 institutionsQ2 2022: 58 institutionsQ3 2022: 70 institutionsQ4 2022: 64 institutionsQ1 2023: 61 institutionsQ2 2023: 77 institutionsQ3 2023: 88 institutionsQ4 2023: 133 institutionsQ1 2024: 180 institutionsQ2 2024: 0 institutionsQ3 2024: 0 institutionsQ4 2024: 0 institutionsQ1 2025: 0 institutionsQ2 2025: 0 institutionsQ3 2025: 0 institutionsQ4 2025: 0 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ3 2022: $284.0M
Q1 2021: $145.0MQ2 2021: $118.5MQ3 2021: $163.5MQ4 2021: $257.1MQ1 2022: $221.8MQ2 2022: $204.4MQ3 2022: $284.0MQ4 2022: $300.8MQ1 2023: $319.4MQ2 2023: $449.3MQ3 2023: $525.8MQ4 2023: $1.12BQ1 2024: $2.56BQ2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: $0Q2 2025: $0Q3 2025: $0Q4 2025: $0Q1 2026: $0Q2 2026: $0
Institutions holding ALPN and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20250$0
Q3 20250$0
Q2 20250$0
Q1 20250$0
Q4 20240$0
Q3 20240$0
Q2 20240$0
Q1 2024180$2.56B
Q4 2023133$1.12B
Q3 202388$525.8M
Q2 202377$449.3M
Q1 202361$319.4M
Q4 202264$300.8M
Q3 202270$284.0M
Q2 202258$204.4M
Q1 202256$221.8M
Q4 202153$257.1M
Q3 202144$163.5M
Q2 202147$118.5M
Q1 202148$145.0M

Institutions, Q3 2022

Shares, value and share of portfolio for each institution holding Alpine Immune Sciences, Inc.; share changes are against Q2 2022.

Institutions holding ALPN in Q3 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Decheng Capital Management III (Cayman), LLC6,708,288$48.3M17.51%+2,000,000+42.5%Added
Ra Capital Management, L.P.4,356,632$31.4M0.67%+4,356,632New
OrbiMed Advisors LLC4,081,592$29.4M0.58%00.0%Unchanged
Great Point Partners LLC3,448,521$24.8M5.98%+2,909,702+540.0%Added
Lynx1 Capital Management LP3,056,420$22.0M19.85%+1,129,551+58.6%Added
Frazier Life Sciences Management, L.P.2,985,757$21.5M1.66%00.0%Unchanged
Paradigm Biocapital Advisors LP2,214,722$15.9M2.25%+1,387,943+167.9%Added
Omega Fund Management, LLC2,029,580$14.6M5.35%00.0%Unchanged
Commodore Capital LP1,325,000$9.54M1.53%+1,325,000New
Octagon Capital Advisors LP1,225,000$8.82M1.52%+1,225,000New
Artal Group S.A.1,193,030$8.59M0.45%+600,000+101.2%Added
BVF Inc1,135,940$8.18M0.34%−139,300−10.9%Reduced
Vanguard Group Inc1,122,800$8.08M0.00%+493,027+78.3%Added
Avidity Partners Management LP998,600$7.19M0.16%+350.0%Added
BlackRock Inc.927,723$6.68M0.00%+49,355+5.6%Added
Renaissance Technologies LLC358,694$2.58M0.00%−38,700−9.7%Reduced
State Street Corp278,982$2.01M0.00%+10,900+4.1%Added
TCG Crossover Management, LLC254,569$1.83M0.55%−323,691−56.0%Reduced
Geode Capital Management, LLC251,504$1.81M0.00%+3,512+1.4%Added
Sphera Funds Management Ltd.200,000$1.44M0.26%+200,000New
Allspring Global Investments Holdings, LLC130,189$937.0K0.00%−6,608−4.8%Reduced
Northern Trust Corp124,478$896.0K0.00%−1,296−1.0%Reduced
Affinity Asset Advisors, LLC110,000$792.0K0.37%+110,000New
Monashee Investment Management LLC100,000$720.0K0.27%+100,000New
Walleye Capital LLC71,355$514.0K0.01%+71,355New
Bridgeway Capital Management, LLC70,611$508.0K0.01%−25,000−26.1%Reduced
Two Sigma Advisers, LP68,475$493.0K0.00%−33,100−32.6%Reduced
Bank of New York Mellon Corp64,480$464.0K0.00%+5,926+10.1%Added
Connor, Clark & Lunn Investment Management Ltd.57,506$414.0K0.00%+7,317+14.6%Added
Dimensional Fund Advisors LP51,370$370.0K0.00%00.0%Unchanged
Alberta Investment Management Corp45,906$331.0K0.00%00.0%Unchanged
Caas Capital Management LP45,354$327.0K0.04%+45,354New
Marshall Wace, LLP45,077$323.0K0.00%+9,147+25.5%Added
Charles Schwab Investment Management Inc39,823$287.0K0.00%00.0%Unchanged
Nuveen Asset Management, LLC28,682$207.0K0.00%+10,236+55.5%Added
Goldman Sachs Group Inc23,939$172.0K0.00%−18,977−44.2%Reduced
Western Wealth Management, LLC24,000$172.0K0.01%−1,120−4.5%Reduced
Two Sigma Investments, LP21,924$158.0K0.00%+1,894+9.5%Added
Rhumbline Advisers21,737$157.0K0.00%+1,333+6.5%Added
Jacobs Levy Equity Management, Inc17,753$128.0K0.00%+17,753New
Price T Rowe Associates Inc12,615$91.0K0.00%+12,615New
Hikari Power Ltd12,445$90.0K0.01%00.0%Unchanged
Morgan Stanley11,562$84.0K0.00%−1,637−12.4%Reduced
JPMorgan Chase & Co10,573$77.0K0.00%+904+9.3%Added
Trexquant Investment LP10,726$77.0K0.00%+10,726New
Jump Financial, LLC10,013$72.0K0.00%+10,013New
Deutsche Bank AG8,049$58.0K0.00%−1,040−11.4%Reduced
American International Group, Inc.7,415$53.0K0.00%+105+1.4%Added
BNP Paribas Arbitrage, SA6,572$47.3K0.00%+3,090+88.7%Added
Bank of America Corp6,591$47.0K0.00%−3,284−33.3%Reduced
California State Teachers Retirement System6,165$44.0K0.00%−514−7.7%Reduced
BIT Capital GmbH6,000$43.2K0.01%+6,000New
New York State Common Retirement Fund5,437$39.0K0.00%+40+0.7%Added
STRS Ohio5,500$39.0K0.00%00.0%Unchanged
Public Employees Retirement System of Ohio4,879$35.0K0.00%+4,879New
Amalgamated Bank2,030$15.0K0.00%+16+0.8%Added
Zurcher Kantonalbank (Zurich Cantonalbank)2,045$15.0K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)1,604$12.0K0.00%−19,605−92.4%Reduced
Legal & General Group Plc1,442$10.0K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.911$6.00K0.00%00.0%Unchanged
Barclays PLC662$5.00K0.00%−121−15.5%Reduced
Citigroup Inc619$4.00K0.00%−978−61.2%Reduced
China Universal Asset Management Co., Ltd.285$2.00K0.00%+285New
Wells Fargo & Company127$1.00K0.00%−163−56.2%Reduced
FMR LLC202$1.00K0.00%+68+50.7%Added
Royal Bank of Canada190$1.00K0.00%+102+115.9%Added
Daiwa Securities Group Inc.85$1.00K0.00%00.0%Unchanged
Credit Suisse AG85$1.00K0.00%+70+466.7%Added
Simplex Trading, LLC129$00.00%−267−67.4%Reduced
Tradewinds Capital Management, LLC15$00.00%+15New
Western Standard LLC0$00.00%−50,328−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−14,121−100.0%Sold out
Lazard Asset Management LLC0$00.00%−4,617−100.0%Sold out
UBS Group AG0$00.00%−1,200−100.0%Sold out