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Alpine Immune Sciences, Inc.

ALPNDelisted May 20, 2024
Industry
Pharmaceutical Preparations
SEC CIK
0001626199

Alpine Immune Sciences, Inc. was delisted on May 20, 2024; its insiders filed their last Form 4 on May 20, 2024; 180 institutions reported holding it in 13F filings for Q1 2024, worth $2.56B in total; no superinvestor held it.

13F holders, Q4 2023

Institutional positions in Alpine Immune Sciences, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
133
+46 vs. Q3 2023
Shares held
58.9M
+19.7M (+50.3%) vs. Q3 2023
Total value
$1.12B
+$674.1M (+150.1%) vs. Q3 2023
New holders
55
62 more added
Sold out
9
10 more reduced

1 institution that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALPN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 133 institutions
Q1 2021: 48 institutionsQ2 2021: 47 institutionsQ3 2021: 44 institutionsQ4 2021: 53 institutionsQ1 2022: 56 institutionsQ2 2022: 58 institutionsQ3 2022: 70 institutionsQ4 2022: 64 institutionsQ1 2023: 61 institutionsQ2 2023: 77 institutionsQ3 2023: 88 institutionsQ4 2023: 133 institutionsQ1 2024: 180 institutionsQ2 2024: 0 institutionsQ3 2024: 0 institutionsQ4 2024: 0 institutionsQ1 2025: 0 institutionsQ2 2025: 0 institutionsQ3 2025: 0 institutionsQ4 2025: 0 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ4 2023: $1.12B
Q1 2021: $145.0MQ2 2021: $118.5MQ3 2021: $163.5MQ4 2021: $257.1MQ1 2022: $221.8MQ2 2022: $204.4MQ3 2022: $284.0MQ4 2022: $300.8MQ1 2023: $319.4MQ2 2023: $449.3MQ3 2023: $525.8MQ4 2023: $1.12BQ1 2024: $2.56BQ2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: $0Q2 2025: $0Q3 2025: $0Q4 2025: $0Q1 2026: $0Q2 2026: $0
Institutions holding ALPN and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20250$0
Q3 20250$0
Q2 20250$0
Q1 20250$0
Q4 20240$0
Q3 20240$0
Q2 20240$0
Q1 2024180$2.56B
Q4 2023133$1.12B
Q3 202388$525.8M
Q2 202377$449.3M
Q1 202361$319.4M
Q4 202264$300.8M
Q3 202270$284.0M
Q2 202258$204.4M
Q1 202256$221.8M
Q4 202153$257.1M
Q3 202144$163.5M
Q2 202147$118.5M
Q1 202148$145.0M

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Alpine Immune Sciences, Inc.; share changes are against Q3 2023.

Institutions holding ALPN in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Decheng Capital LLC7,083,288$135.0M37.72%+7,083,288New
Ra Capital Management, L.P.4,909,763$93.6M1.46%+218,585+4.7%Added
Lynx1 Capital Management LP3,813,926$72.7M28.58%+1,409,312+58.6%Added
Great Point Partners LLC3,703,433$70.6M12.03%+624,800+20.3%Added
Paradigm Biocapital Advisors LP3,176,743$60.5M2.84%+755,000+31.2%Added
Frazier Life Sciences Management, L.P.3,131,008$59.7M3.19%+145,251+4.9%Added
BlackRock Inc.3,058,498$58.3M0.00%+706,581+30.0%Added
Cormorant Asset Management, LP2,550,000$48.6M2.33%+650,000+34.2%Added
OrbiMed Advisors LLC2,535,245$48.3M0.97%−1,546,347−37.9%Reduced
Vanguard Group Inc2,234,767$42.6M0.00%+759,888+51.5%Added
Price T Rowe Associates Inc1,687,278$32.2M0.00%+290,834+20.8%Added
Commodore Capital LP1,610,000$30.7M2.68%+285,000+21.5%Added
State Street Corp1,390,029$26.5M0.00%+784,484+129.6%Added
Octagon Capital Advisors LP1,241,300$23.7M3.79%+491,300+65.5%Added
Franklin Resources Inc1,220,333$23.3M0.01%+1,220,333New
Woodline Partners LP1,000,106$19.1M0.21%−38,671−3.7%Reduced
Citadel Advisors LLC875,257$16.7M0.02%+847,083+3,006.6%Added
Vivo Capital, LLC819,275$15.6M1.28%−95,638−10.5%Reduced
Geode Capital Management, LLC764,347$14.6M0.00%+135,422+21.5%Added
Morgan Stanley718,741$13.7M0.00%+665,268+1,244.1%Added
Adage Capital Partners GP, L.L.C.714,590$13.6M0.03%+714,590New
Janus Henderson Group PLC583,239$11.1M0.01%+583,239New
Ikarian Capital, LLC487,248$9.29M2.54%+487,248New
Candriam Luxembourg S.C.A.470,000$8.96M0.06%+470,000New
Two Sigma Investments, LP378,413$7.21M0.02%+187,824+98.5%Added
Walleye Capital LLC365,940$6.97M0.10%+179,667+96.5%Added
Ally Bridge Group (NY) LLC357,271$6.81M4.90%+357,271New
Silverarc Capital Management, LLC297,789$5.68M1.75%+297,789New
Charles Schwab Investment Management Inc297,452$5.67M0.00%+63,196+27.0%Added
Northern Trust Corp296,695$5.66M0.00%+26,271+9.7%Added
D. E. Shaw & Co., Inc.295,542$5.63M0.01%+246,911+507.7%Added
Millennium Management LLC273,066$5.20M0.00%+190,140+229.3%Added
Two Sigma Advisers, LP264,075$5.03M0.01%+18,000+7.3%Added
Nan Fung Group Holdings Ltd263,940$5.03M3.13%+81,660+44.8%Added
StemPoint Capital LP246,178$4.69M1.26%+246,178New
Invesco Ltd.241,776$4.61M0.00%+24,640+11.3%Added
FMR LLC238,546$4.55M0.00%−226,266−48.7%Reduced
Sphera Funds Management Ltd.234,841$4.48M0.83%+54,841+30.5%Added
Dimensional Fund Advisors LP233,881$4.46M0.00%+66,573+39.8%Added
Voloridge Investment Management, LLC233,750$4.46M0.02%+233,750New
Marshall Wace, LLP221,118$4.21M0.01%+221,118New
Renaissance Technologies LLC216,685$4.13M0.01%−71,509−24.8%Reduced
ExodusPoint Capital Management, LP208,974$3.98M0.05%−8,081−3.7%Reduced
Qube Research & Technologies Ltd205,766$3.92M0.01%+195,696+1,943.4%Added
Goldman Sachs Group Inc197,944$3.77M0.00%+131,499+197.9%Added
Hudson Bay Capital Management LP197,019$3.76M0.03%+197,019New
Exome Asset Management LLC173,500$3.31M3.27%+173,500New
EAM Investors, LLC162,685$3.10M0.56%+162,685New
Jennison Associates LLC141,095$2.69M0.00%+141,095New
Ensign Peak Advisors, Inc129,975$2.48M0.00%+129,975New
Nuveen Asset Management, LLC129,966$2.48M0.00%+36,581+39.2%Added
Deutsche Bank AG129,479$2.47M0.00%+111,968+639.4%Added
Boothbay Fund Management, LLC116,823$2.23M0.08%+116,823New
Wellington Management Group LLP109,882$2.09M0.00%+70,151+176.6%Added
BNP Paribas Arbitrage, SA106,941$2.04M0.00%+93,423+691.1%Added
Bank of New York Mellon Corp102,352$1.95M0.00%+9,629+10.4%Added
Jefferies Financial Group Inc.100,152$1.91M0.03%+100,152New
Laurion Capital Management LP97,200$1.85M0.07%+97,200New
Bank of America Corp91,766$1.75M0.00%+70,466+330.8%Added
Barclays PLC80,297$1.53M0.00%+71,171+779.9%Added
Rafferty Asset Management, LLC80,162$1.53M0.01%+80,162New
Altium Capital Management LP78,723$1.50M1.03%+78,723New
Jane Street Group, LLC69,453$1.32M0.00%+51,255+281.7%Added
UBS Group AG65,807$1.25M0.00%+46,760+245.5%Added
Ghisallo Capital Management LLC65,000$1.24M0.13%+65,000New
Swiss National Bank57,200$1.09M0.00%+15,000+35.5%Added
Jump Financial, LLC55,720$1.06M0.03%+55,720New
Trexquant Investment LP53,780$1.03M0.02%+25,202+88.2%Added
Artal Group S.A.50,759$967.0K0.03%−1,142,271−95.7%Reduced
Monashee Investment Management LLC74,792$964.1K0.17%+74,792New
Cubist Systematic Strategies, LLC48,670$927.6K0.01%+48,670New
Rhumbline Advisers43,721$833.3K0.00%+2,318+5.6%Added
Prelude Capital Management, LLC41,500$791.0K0.07%+41,500New
AWM Investment Company, Inc.40,000$762.4K0.10%+40,000New
HighVista Strategies LLC39,861$759.8K0.28%00.0%Unchanged
Alps Advisors Inc39,591$754.6K0.01%+39,591New
ClariVest Asset Management LLC38,800$739.5K0.04%+38,800New
Citigroup Inc35,777$681.9K0.00%+35,107+5,239.9%Added
TD Asset Management Inc33,200$632.8K0.00%+33,200New
JPMorgan Chase & Co33,074$630.4K0.00%+1,765+5.6%Added
California State Teachers Retirement System31,163$594.0K0.00%+7,170+29.9%Added
Alliancebernstein L.P.30,040$572.6K0.00%+11,540+62.4%Added
HighPoint Advisor Group LLC15,190$570.0K0.04%+15,190New
State of Wisconsin Investment Board28,949$551.8K0.00%+6,752+30.4%Added
Algert Global LLC28,290$539.2K0.02%+8,280+41.4%Added
AQR Capital Management LLC26,970$514.0K0.00%+26,970New
Manufacturers Life Insurance Company, The26,778$510.4K0.00%−1,605−5.7%Reduced
Credit Suisse AG26,744$509.7K0.00%+11,535+75.8%Added
Legal & General Group Plc26,263$500.6K0.00%+3,548+15.6%Added
Walleye Trading LLC25,596$487.9K0.01%+25,596New
Occudo Quantitative Strategies LP25,554$487.1K0.07%+25,554New
Capstone Investment Advisors, LLC25,289$482.0K0.01%+25,289New
Driehaus Capital Management LLC23,566$449.2K0.01%+4,930+26.5%Added
SEI Investments Co23,211$442.4K0.00%+23,211New
Susquehanna International Group, LLP22,775$434.1K0.00%+22,775New
Ziegler Capital Management, LLC22,383$426.6K0.02%+22,383New
Squarepoint Ops LLC21,878$417.0K0.00%+21,878New
Mirae Asset Global Investments Co., Ltd.20,177$384.6K0.00%+3,024+17.6%Added
Corton Capital Inc.16,934$322.8K0.10%+16,934New
MetLife Investment Management16,818$320.6K0.00%00.0%Unchanged