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Alpine Immune Sciences, Inc.

ALPNDelisted May 20, 2024
Industry
Pharmaceutical Preparations
SEC CIK
0001626199

Alpine Immune Sciences, Inc. was delisted on May 20, 2024; its insiders filed their last Form 4 on May 20, 2024; 180 institutions reported holding it in 13F filings for Q1 2024, worth $2.56B in total; no superinvestor held it.

13F holders, Q1 2023

Institutional positions in Alpine Immune Sciences, Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
61
−3 vs. Q4 2022
Shares held
41.4M
+454.1K (+1.1%) vs. Q4 2022
Total value
$319.4M
+$18.6M (+6.2%) vs. Q4 2022
New holders
5
26 more added
Sold out
8
13 more reduced

Compare with Q4 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALPN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2023: 61 institutions
Q1 2021: 48 institutionsQ2 2021: 47 institutionsQ3 2021: 44 institutionsQ4 2021: 53 institutionsQ1 2022: 56 institutionsQ2 2022: 58 institutionsQ3 2022: 70 institutionsQ4 2022: 64 institutionsQ1 2023: 61 institutionsQ2 2023: 77 institutionsQ3 2023: 88 institutionsQ4 2023: 133 institutionsQ1 2024: 180 institutionsQ2 2024: 0 institutionsQ3 2024: 0 institutionsQ4 2024: 0 institutionsQ1 2025: 0 institutionsQ2 2025: 0 institutionsQ3 2025: 0 institutionsQ4 2025: 0 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ1 2023: $319.4M
Q1 2021: $145.0MQ2 2021: $118.5MQ3 2021: $163.5MQ4 2021: $257.1MQ1 2022: $221.8MQ2 2022: $204.4MQ3 2022: $284.0MQ4 2022: $300.8MQ1 2023: $319.4MQ2 2023: $449.3MQ3 2023: $525.8MQ4 2023: $1.12BQ1 2024: $2.56BQ2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: $0Q2 2025: $0Q3 2025: $0Q4 2025: $0Q1 2026: $0Q2 2026: $0
Institutions holding ALPN and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20250$0
Q3 20250$0
Q2 20250$0
Q1 20250$0
Q4 20240$0
Q3 20240$0
Q2 20240$0
Q1 2024180$2.56B
Q4 2023133$1.12B
Q3 202388$525.8M
Q2 202377$449.3M
Q1 202361$319.4M
Q4 202264$300.8M
Q3 202270$284.0M
Q2 202258$204.4M
Q1 202256$221.8M
Q4 202153$257.1M
Q3 202144$163.5M
Q2 202147$118.5M
Q1 202148$145.0M

Institutions, Q1 2023

Shares, value and share of portfolio for each institution holding Alpine Immune Sciences, Inc.; share changes are against Q4 2022.

Institutions holding ALPN in Q1 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Decheng Capital Management III (Cayman), LLC6,708,288$51.8M20.89%00.0%Unchanged
Ra Capital Management, L.P.4,688,115$36.2M0.82%+290,747+6.6%Added
OrbiMed Advisors LLC4,081,592$31.5M0.62%00.0%Unchanged
Great Point Partners LLC3,740,761$28.9M5.71%+103,043+2.8%Added
Lynx1 Capital Management LP3,136,173$24.2M20.18%+10,000+0.3%Added
Frazier Life Sciences Management, L.P.2,985,757$23.1M1.67%00.0%Unchanged
Paradigm Biocapital Advisors LP2,317,634$17.9M1.70%00.0%Unchanged
Omega Fund Management, LLC2,029,580$15.7M10.22%00.0%Unchanged
BlackRock Inc.1,552,920$12.0M0.00%+116,060+8.1%Added
Vanguard Group Inc1,369,709$10.6M0.00%+9,206+0.7%Added
Commodore Capital LP1,325,000$10.2M1.56%00.0%Unchanged
Octagon Capital Advisors LP1,202,000$9.28M1.34%−23,000−1.9%Reduced
Artal Group S.A.1,193,030$9.21M0.55%00.0%Unchanged
Avidity Partners Management LP989,500$7.64M0.25%−38,700−3.8%Reduced
BVF Inc858,339$6.63M0.24%−277,601−24.4%Reduced
Geode Capital Management, LLC556,207$4.29M0.00%+70,457+14.5%Added
State Street Corp346,671$2.68M0.00%+43,253+14.3%Added
Renaissance Technologies LLC330,294$2.55M0.00%−2,600−0.8%Reduced
TCG Crossover Management, LLC253,069$1.95M0.38%00.0%Unchanged
Affinity Asset Advisors, LLC247,891$1.91M0.74%00.0%Unchanged
Sphera Funds Management Ltd.200,000$1.54M0.33%00.0%Unchanged
Ghost Tree Capital, LLC200,000$1.54M0.58%+200,000New
Northern Trust Corp193,987$1.50M0.00%+2,415+1.3%Added
Dimensional Fund Advisors LP139,672$1.08M0.00%+40,865+41.4%Added
HighVista Strategies LLC90,287$697.0K0.57%+90,287New
Bank of New York Mellon Corp71,806$554.3K0.00%−11,785−14.1%Reduced
Charles Schwab Investment Management Inc67,266$519.3K0.00%+2,770+4.3%Added
Connor, Clark & Lunn Investment Management Ltd.54,237$418.7K0.00%−4,071−7.0%Reduced
JPMorgan Chase & Co48,149$372.0K0.00%+33,919+238.4%Added
Two Sigma Advisers, LP40,975$316.3K0.00%−24,200−37.1%Reduced
Walleye Capital LLC34,117$263.4K0.01%+34,117New
Rhumbline Advisers32,848$254.0K0.00%+6,615+25.2%Added
Nuveen Asset Management, LLC31,729$245.0K0.00%00.0%Unchanged
Goldman Sachs Group Inc30,857$238.2K0.00%+368+1.2%Added
Morgan Stanley27,914$215.5K0.00%+10,353+59.0%Added
Bank of America Corp23,500$181.4K0.00%−166−0.7%Reduced
BNP Paribas Arbitrage, SA20,518$158.4K0.00%+5,007+32.3%Added
Price T Rowe Associates Inc19,625$152.0K0.00%+224+1.2%Added
Deutsche Bank AG14,751$113.9K0.00%+6,596+80.9%Added
Hikari Power Ltd12,445$96.0K0.01%00.0%Unchanged
Barclays PLC12,079$93.3K0.00%+5,999+98.7%Added
MetLife Investment Management12,028$92.9K0.00%00.0%Unchanged
Western Wealth Management, LLC12,000$92.6K0.01%00.0%Unchanged
SG Americas Securities, LLC11,927$92.0K0.00%+11,927New
American International Group, Inc.11,418$88.1K0.00%+708+6.6%Added
Susquehanna International Group, LLP10,634$82.1K0.00%−11,528−52.0%Reduced
California State Teachers Retirement System8,796$67.9K0.00%−242−2.7%Reduced
UBS Group AG7,993$61.7K0.00%+5,717+251.2%Added
New York State Common Retirement Fund5,505$42.5K0.00%+68+1.3%Added
Wells Fargo & Company4,392$33.9K0.00%+4,392New
Amalgamated Bank2,833$22.0K0.00%+448+18.8%Added
Legal & General Group Plc2,473$19.1K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.1,900$14.7K0.00%+989+108.6%Added
Tower Research Capital LLC (TRC)1,499$12.0K0.00%+478+46.8%Added
Royal Bank of Canada1,327$10.0K0.00%−1,828−57.9%Reduced
FMR LLC1,256$9.70K0.00%+576+84.7%Added
China Universal Asset Management Co., Ltd.623$4.81K0.00%+156+33.4%Added
Metropolitan Life Insurance Co537$4.15K0.00%−881−62.1%Reduced
Citigroup Inc523$4.04K0.00%−71−12.0%Reduced
Daiwa Securities Group Inc.85$1.00K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC12$00.00%00.0%Unchanged
Cheyne Capital Management (UK) LLP0$00.00%−181,886−100.0%Sold out
Pura Vida Investments, LLC0$00.00%−30,924−100.0%Sold out
Citadel Advisors LLC0$00.00%−21,204−100.0%Sold out
Trexquant Investment LP0$00.00%−16,763−100.0%Sold out
Allspring Global Investments Holdings, LLC0$00.00%−4,453−100.0%Sold out
Zurcher Kantonalbank (Zurich Cantonalbank)0$00.00%−1,714−100.0%Sold out
Tradewinds Capital Management, LLC0$00.00%−15−100.0%Sold out
Credit Suisse AG0$00.00%−1−100.0%Sold out