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Alpine Immune Sciences, Inc.

ALPNDelisted May 20, 2024
Industry
Pharmaceutical Preparations
SEC CIK
0001626199

Alpine Immune Sciences, Inc. was delisted on May 20, 2024; its insiders filed their last Form 4 on May 20, 2024; 180 institutions reported holding it in 13F filings for Q1 2024, worth $2.56B in total; no superinvestor held it.

13F holders, Q2 2021

Institutional positions in Alpine Immune Sciences, Inc. as of Jun 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
47
−1 vs. Q1 2021
Shares held
13.2M
−533.4K (−3.9%) vs. Q1 2021
Total value
$118.5M
−$26.5M (−18.3%) vs. Q1 2021
New holders
15
8 more added
Sold out
16
14 more reduced

Compare with Q1 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALPN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2021: 47 institutions
Q1 2021: 48 institutionsQ2 2021: 47 institutionsQ3 2021: 44 institutionsQ4 2021: 53 institutionsQ1 2022: 56 institutionsQ2 2022: 58 institutionsQ3 2022: 70 institutionsQ4 2022: 64 institutionsQ1 2023: 61 institutionsQ2 2023: 77 institutionsQ3 2023: 88 institutionsQ4 2023: 133 institutionsQ1 2024: 180 institutionsQ2 2024: 0 institutionsQ3 2024: 0 institutionsQ4 2024: 0 institutionsQ1 2025: 0 institutionsQ2 2025: 0 institutionsQ3 2025: 0 institutionsQ4 2025: 0 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ2 2021: $118.5M
Q1 2021: $145.0MQ2 2021: $118.5MQ3 2021: $163.5MQ4 2021: $257.1MQ1 2022: $221.8MQ2 2022: $204.4MQ3 2022: $284.0MQ4 2022: $300.8MQ1 2023: $319.4MQ2 2023: $449.3MQ3 2023: $525.8MQ4 2023: $1.12BQ1 2024: $2.56BQ2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: $0Q2 2025: $0Q3 2025: $0Q4 2025: $0Q1 2026: $0Q2 2026: $0
Institutions holding ALPN and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20250$0
Q3 20250$0
Q2 20250$0
Q1 20250$0
Q4 20240$0
Q3 20240$0
Q2 20240$0
Q1 2024180$2.56B
Q4 2023133$1.12B
Q3 202388$525.8M
Q2 202377$449.3M
Q1 202361$319.4M
Q4 202264$300.8M
Q3 202270$284.0M
Q2 202258$204.4M
Q1 202256$221.8M
Q4 202153$257.1M
Q3 202144$163.5M
Q2 202147$118.5M
Q1 202148$145.0M

Institutions, Q2 2021

Shares, value and share of portfolio for each institution holding Alpine Immune Sciences, Inc.; share changes are against Q1 2021.

Institutions holding ALPN in Q2 2021
InstitutionSharesValue% of portfolioChange in sharesAction
OrbiMed Advisors LLC3,070,955$27.6M0.28%00.0%Unchanged
Frazier Management LLC2,571,450$23.1M2.13%00.0%Unchanged
Avidity Partners Management LP1,495,000$13.5M0.36%−16,000−1.1%Reduced
Omega Fund Management, LLC1,284,900$11.6M1.31%00.0%Unchanged
Artal Group S.A.593,030$5.34M0.12%00.0%Unchanged
Vanguard Group Inc575,217$5.18M0.00%−1260.0%Reduced
BlackRock Inc.544,155$4.90M0.00%+517,399+1,933.8%Added
EcoR1 Capital, LLC522,635$4.70M0.18%−218,655−29.5%Reduced
Renaissance Technologies LLC398,994$3.59M0.00%+2,100+0.5%Added
Ikarian Capital, LLC300,454$2.70M0.48%−4,285−1.4%Reduced
Samsara BioCapital, LLC275,169$2.48M0.33%−124,021−31.1%Reduced
Geode Capital Management, LLC191,538$1.72M0.00%+99,396+107.9%Added
State Street Corp173,119$1.56M0.00%+173,119New
Bridgeway Capital Management, LLC153,611$1.38M0.02%+153,611New
Tiger Management L.L.C.137,728$1.24M0.22%00.0%Unchanged
Deutsche Bank AG134,057$1.21M0.00%−110,275−45.1%Reduced
Northern Trust Corp113,579$1.02M0.00%+93,666+470.4%Added
DAFNA Capital Management LLC113,302$1.02M0.21%00.0%Unchanged
Two Sigma Advisers, LP69,175$623.0K0.00%−56,800−45.1%Reduced
Acadian Asset Management LLC67,156$604.0K0.00%+18,615+38.3%Added
Ensign Peak Advisors, Inc54,580$491.0K0.00%00.0%Unchanged
Dimensional Fund Advisors LP45,300$408.0K0.00%00.0%Unchanged
Bank of New York Mellon Corp41,862$377.0K0.00%+19,178+84.5%Added
Boothbay Fund Management, LLC35,523$320.0K0.01%−1,268−3.4%Reduced
Alps Advisors Inc31,498$283.0K0.00%+31,498New
Charles Schwab Investment Management Inc28,760$259.0K0.00%+28,760New
Hancock Whitney Corp18,721$168.0K0.01%+7,249+63.2%Added
Nuveen Asset Management, LLC18,446$166.0K0.00%+18,446New
Two Sigma Investments, LP16,914$152.0K0.00%−90,467−84.2%Reduced
Leonard Rickey Investment Advisors P.L.L.C.17,013$146.0K0.06%00.0%Unchanged
California State Teachers Retirement System16,137$145.0K0.00%+16,137New
Western Wealth Management, LLC12,000$108.0K0.01%+12,000New
Hikari Power Ltd10,445$94.0K0.01%00.0%Unchanged
New York State Common Retirement Fund10,300$93.0K0.00%+10,300New
American International Group, Inc.6,509$59.0K0.00%+6,509New
JPMorgan Chase & Co4,460$40.0K0.00%+4,460New
Morgan Stanley3,326$30.0K0.00%−2,024−37.8%Reduced
STRS Ohio2,700$24.0K0.00%+2,700New
Bank of America Corp2,226$20.0K0.00%+1,048+89.0%Added
Barclays PLC1,469$13.0K0.00%−12,636−89.6%Reduced
Legal & General Group Plc1,227$11.0K0.00%+1,227New
Ameritas Investment Partners, Inc.911$8.00K0.00%+911New
Tower Research Capital LLC (TRC)714$7.00K0.00%−281−28.2%Reduced
Royal Bank of Canada795$7.00K0.00%+795New
Citigroup Inc552$5.00K0.00%−5,364−90.7%Reduced
BNP Paribas Arbitrage, SA448$4.03K0.00%+448New
Wells Fargo & Company300$3.00K0.00%−66−18.0%Reduced
Soleus Capital Management, L.P.0$00.00%−313,064−100.0%Sold out
Sphera Funds Management Ltd.0$00.00%−198,260−100.0%Sold out
Opaleye Management Inc.0$00.00%−156,500−100.0%Sold out
Pura Vida Investments, LLC0$00.00%−131,981−100.0%Sold out
Millennium Management LLC0$00.00%−96,017−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−59,728−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−36,359−100.0%Sold out
HRT Financial LP0$00.00%−23,593−100.0%Sold out
Citadel Advisors LLC0$00.00%−22,030−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−14,562−100.0%Sold out
Vista Capital Partners, Inc.0$00.00%−14,304−100.0%Sold out
Goldman Sachs Group Inc0$00.00%−10,577−100.0%Sold out
Monashee Investment Management LLC0$00.00%−29,652−100.0%Sold out
Dorsey Wright & Associates0$00.00%−3,380−100.0%Sold out
UBS Group AG0$00.00%−689−100.0%Sold out
Sowell Financial Services LLC0$00.00%−10−100.0%Sold out