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Alpine Immune Sciences, Inc.

ALPNDelisted May 20, 2024
Industry
Pharmaceutical Preparations
SEC CIK
0001626199

Alpine Immune Sciences, Inc. was delisted on May 20, 2024; its insiders filed their last Form 4 on May 20, 2024; 180 institutions reported holding it in 13F filings for Q1 2024, worth $2.56B in total; no superinvestor held it.

13F holders, Q3 2021

Institutional positions in Alpine Immune Sciences, Inc. as of Sep 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
44
−2 vs. Q2 2021
Shares held
15.3M
+2.17M (+16.5%) vs. Q2 2021
Total value
$163.5M
+$45.1M (+38.1%) vs. Q2 2021
New holders
4
18 more added
Sold out
6
13 more reduced

1 institution that held it in Q2 2021 haven't filed for Q3 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALPN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2021: 44 institutions
Q1 2021: 48 institutionsQ2 2021: 47 institutionsQ3 2021: 44 institutionsQ4 2021: 53 institutionsQ1 2022: 56 institutionsQ2 2022: 58 institutionsQ3 2022: 70 institutionsQ4 2022: 64 institutionsQ1 2023: 61 institutionsQ2 2023: 77 institutionsQ3 2023: 88 institutionsQ4 2023: 133 institutionsQ1 2024: 180 institutionsQ2 2024: 0 institutionsQ3 2024: 0 institutionsQ4 2024: 0 institutionsQ1 2025: 0 institutionsQ2 2025: 0 institutionsQ3 2025: 0 institutionsQ4 2025: 0 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ3 2021: $163.5M
Q1 2021: $145.0MQ2 2021: $118.5MQ3 2021: $163.5MQ4 2021: $257.1MQ1 2022: $221.8MQ2 2022: $204.4MQ3 2022: $284.0MQ4 2022: $300.8MQ1 2023: $319.4MQ2 2023: $449.3MQ3 2023: $525.8MQ4 2023: $1.12BQ1 2024: $2.56BQ2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: $0Q2 2025: $0Q3 2025: $0Q4 2025: $0Q1 2026: $0Q2 2026: $0
Institutions holding ALPN and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20250$0
Q3 20250$0
Q2 20250$0
Q1 20250$0
Q4 20240$0
Q3 20240$0
Q2 20240$0
Q1 2024180$2.56B
Q4 2023133$1.12B
Q3 202388$525.8M
Q2 202377$449.3M
Q1 202361$319.4M
Q4 202264$300.8M
Q3 202270$284.0M
Q2 202258$204.4M
Q1 202256$221.8M
Q4 202153$257.1M
Q3 202144$163.5M
Q2 202147$118.5M
Q1 202148$145.0M

Institutions, Q3 2021

Shares, value and share of portfolio for each institution holding Alpine Immune Sciences, Inc.; share changes are against Q2 2021.

Institutions holding ALPN in Q3 2021
InstitutionSharesValue% of portfolioChange in sharesAction
OrbiMed Advisors LLC4,081,592$43.6M0.48%+1,010,637+32.9%Added
Omega Fund Management, LLC2,029,580$21.7M2.43%+744,680+58.0%Added
Avidity Partners Management LP1,932,000$20.6M0.53%+437,000+29.2%Added
Frazier Management LLC1,771,844$18.9M1.51%−799,606−31.1%Reduced
BVF Inc1,589,495$17.0M0.66%+1,589,495New
Artal Group S.A.593,030$6.33M0.16%00.0%Unchanged
Vanguard Group Inc580,478$6.19M0.00%+5,261+0.9%Added
BlackRock Inc.547,782$5.84M0.00%+3,627+0.7%Added
Logos Global Management LP425,000$4.54M0.33%+425,000New
Renaissance Technologies LLC395,594$4.22M0.01%−3,400−0.9%Reduced
State Street Corp197,796$2.11M0.00%+24,677+14.3%Added
Geode Capital Management, LLC194,021$2.07M0.00%+2,483+1.3%Added
Bridgeway Capital Management, LLC153,611$1.64M0.03%00.0%Unchanged
Tiger Management L.L.C.137,728$1.47M0.27%00.0%Unchanged
DAFNA Capital Management LLC111,501$1.19M0.32%−1,801−1.6%Reduced
Northern Trust Corp107,234$1.14M0.00%−6,345−5.6%Reduced
Ensign Peak Advisors, Inc72,930$778.0K0.00%+18,350+33.6%Added
Wells Fargo & Company54,878$585.0K0.00%+54,578+18,192.7%Added
Bank of New York Mellon Corp50,538$539.0K0.00%+8,676+20.7%Added
Dimensional Fund Advisors LP50,364$538.0K0.00%+5,064+11.2%Added
Two Sigma Advisers, LP41,675$445.0K0.00%−27,500−39.8%Reduced
Two Sigma Investments, LP39,218$418.0K0.00%+22,304+131.9%Added
Alps Advisors Inc29,304$313.0K0.00%−2,194−7.0%Reduced
Charles Schwab Investment Management Inc24,623$263.0K0.00%−4,137−14.4%Reduced
Nuveen Asset Management, LLC18,446$184.0K0.00%00.0%Unchanged
Leonard Rickey Investment Advisors P.L.L.C.17,013$182.0K0.08%00.0%Unchanged
HighVista Strategies LLC14,268$152.0K0.10%+14,268New
Hikari Power Ltd10,445$111.0K0.01%00.0%Unchanged
EcoR1 Capital, LLC7,001$75.0K0.00%−515,634−98.7%Reduced
Deutsche Bank AG6,680$71.0K0.00%−127,377−95.0%Reduced
American International Group, Inc.6,358$68.0K0.00%−151−2.3%Reduced
California State Teachers Retirement System6,215$66.0K0.00%−9,922−61.5%Reduced
New York State Common Retirement Fund5,417$58.0K0.00%−4,883−47.4%Reduced
Barclays PLC4,747$51.0K0.00%+3,278+223.1%Added
JPMorgan Chase & Co4,460$48.0K0.00%00.0%Unchanged
Bank of America Corp3,371$36.0K0.00%+1,145+51.4%Added
Morgan Stanley2,734$28.0K0.00%−592−17.8%Reduced
BNP Paribas Arbitrage, SA2,116$22.6K0.00%+1,668+372.3%Added
Tower Research Capital LLC (TRC)1,988$21.0K0.00%+1,274+178.4%Added
Citigroup Inc1,326$14.0K0.00%+774+140.2%Added
Legal & General Group Plc1,227$13.0K0.00%00.0%Unchanged
Royal Bank of Canada1,183$12.0K0.00%+388+48.8%Added
UBS Group AG1,142$12.0K0.00%+1,142New
Ameritas Investment Partners, Inc.911$10.0K0.00%00.0%Unchanged
Ikarian Capital, LLC0$00.00%−300,454−100.0%Sold out
Samsara BioCapital, LLC0$00.00%−275,169−100.0%Sold out
Acadian Asset Management LLC0$00.00%−67,156−100.0%Sold out
Boothbay Fund Management, LLC0$00.00%−35,523−100.0%Sold out
Hancock Whitney Corp0$00.00%−18,721−100.0%Sold out
STRS Ohio0$00.00%−2,700−100.0%Sold out
Western Wealth Management, LLC––––Not filed