Alpine Immune Sciences, Inc.
ALPNDelisted May 20, 2024- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001626199
Alpine Immune Sciences, Inc. was delisted on May 20, 2024; its insiders filed their last Form 4 on May 20, 2024; 180 institutions reported holding it in 13F filings for Q1 2024, worth $2.56B in total; no superinvestor held it.
13F holders, Q1 2024
Institutional positions in Alpine Immune Sciences, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
ALPN is no longer listed, so this page shows Q1 2024. 13F filings for later quarters list far fewer holders.
- Institutional holders
- 180
- +47 vs. Q4 2023
- Shares held
- 64.6M
- +5.65M (+9.6%) vs. Q4 2023
- Total value
- $2.56B
- +$1.44B (+128.0%) vs. Q4 2023
- New holders
- 63
- 67 more added
- Sold out
- 16
- 41 more reduced
Compare with Q4 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ALPN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 0 | $0 |
| Q1 2026 | 0 | $0 |
| Q4 2025 | 0 | $0 |
| Q3 2025 | 0 | $0 |
| Q2 2025 | 0 | $0 |
| Q1 2025 | 0 | $0 |
| Q4 2024 | 0 | $0 |
| Q3 2024 | 0 | $0 |
| Q2 2024 | 0 | $0 |
| Q1 2024 | 180 | $2.56B |
| Q4 2023 | 133 | $1.12B |
| Q3 2023 | 88 | $525.8M |
| Q2 2023 | 77 | $449.3M |
| Q1 2023 | 61 | $319.4M |
| Q4 2022 | 64 | $300.8M |
| Q3 2022 | 70 | $284.0M |
| Q2 2022 | 58 | $204.4M |
| Q1 2022 | 56 | $221.8M |
| Q4 2021 | 53 | $257.1M |
| Q3 2021 | 44 | $163.5M |
| Q2 2021 | 47 | $118.5M |
| Q1 2021 | 48 | $145.0M |
Institutions, Q1 2024
Shares, value and share of portfolio for each institution holding Alpine Immune Sciences, Inc.; share changes are against Q4 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Decheng Capital LLC | 8,317,924 | $329.7M | 44.22% | +1,234,636+17.4% | Added |
| Avoro Capital Advisors LLC | 5,775,000 | $228.9M | 2.67% | +5,775,000 | New |
| BlackRock Inc. | 3,575,092 | $141.7M | 0.00% | +516,594+16.9% | Added |
| Frazier Life Sciences Management, L.P. | 3,131,008 | $124.1M | 5.24% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 3,080,220 | $122.1M | 0.01% | +1,392,942+82.6% | Added |
| State Street Corp | 2,845,839 | $112.8M | 0.01% | +1,455,810+104.7% | Added |
| Vanguard Group Inc | 2,712,285 | $107.5M | 0.00% | +477,518+21.4% | Added |
| Cormorant Asset Management, LP | 2,700,000 | $107.0M | 4.72% | +150,000+5.9% | Added |
| OrbiMed Advisors LLC | 2,680,496 | $106.3M | 2.08% | +145,251+5.7% | Added |
| Lynx1 Capital Management LP | 2,253,183 | $89.3M | 23.00% | −1,560,743−40.9% | Reduced |
| Paradigm Biocapital Advisors LP | 2,121,163 | $84.1M | 2.96% | −1,055,580−33.2% | Reduced |
| Darwin Global Management, Ltd. | 1,982,016 | $78.6M | 10.46% | +1,982,016 | New |
| Commodore Capital LP | 1,375,000 | $54.5M | 3.64% | −235,000−14.6% | Reduced |
| Octagon Capital Advisors LP | 1,241,300 | $49.2M | 5.98% | 00.0% | Unchanged |
| Avidity Partners Management LP | 1,174,700 | $46.6M | 1.66% | +1,174,700 | New |
| Great Point Partners LLC | 1,128,499 | $44.7M | 6.97% | −2,574,934−69.5% | Reduced |
| Franklin Resources Inc | 1,093,203 | $43.3M | 0.01% | −127,130−10.4% | Reduced |
| Geode Capital Management, LLC | 910,599 | $36.1M | 0.00% | +146,252+19.1% | Added |
| Morgan Stanley | 789,645 | $31.3M | 0.00% | +70,904+9.9% | Added |
| Two Sigma Advisers, LP | 668,775 | $26.5M | 0.06% | +404,700+153.3% | Added |
| Vivo Capital, LLC | 520,505 | $20.8M | 1.63% | −298,770−36.5% | Reduced |
| Two Sigma Investments, LP | 519,971 | $20.6M | 0.05% | +141,558+37.4% | Added |
| Nuveen Asset Management, LLC | 513,175 | $20.3M | 0.01% | +383,209+294.9% | Added |
| First Light Asset Management, LLC | 501,243 | $19.9M | 1.52% | +501,243 | New |
| Janus Henderson Group PLC | 450,827 | $17.8M | 0.01% | −132,412−22.7% | Reduced |
| D. E. Shaw & Co., Inc. | 428,555 | $17.0M | 0.02% | +133,013+45.0% | Added |
| Candriam Luxembourg S.C.A. | 415,000 | $16.5M | 0.11% | −55,000−11.7% | Reduced |
| Eventide Asset Management, LLC | 408,542 | $16.2M | 0.25% | +408,542 | New |
| Artal Group S.A. | 405,784 | $16.1M | 0.41% | +355,025+699.4% | Added |
| Balyasny Asset Management LLC | 372,995 | $14.8M | 0.04% | +372,995 | New |
| Vestal Point Capital, LP | 350,000 | $13.9M | 1.15% | +350,000 | New |
| Northern Trust Corp | 341,701 | $13.5M | 0.00% | +45,006+15.2% | Added |
| Charles Schwab Investment Management Inc | 339,142 | $13.4M | 0.00% | +41,690+14.0% | Added |
| Bank of New York Mellon Corp | 325,943 | $12.9M | 0.00% | +223,591+218.5% | Added |
| Adage Capital Partners GP, L.L.C. | 310,000 | $12.3M | 0.02% | −404,590−56.6% | Reduced |
| Invesco Ltd. | 272,627 | $10.8M | 0.00% | +30,851+12.8% | Added |
| Voloridge Investment Management, LLC | 267,232 | $10.6M | 0.04% | +33,482+14.3% | Added |
| Nan Fung Group Holdings Ltd | 263,940 | $10.5M | 9.69% | 00.0% | Unchanged |
| Ikarian Capital, LLC | 261,365 | $10.4M | 2.82% | −225,883−46.4% | Reduced |
| Atika Capital Management LLC | 256,000 | $10.1M | 1.14% | +256,000 | New |
| Woodline Partners LP | 254,334 | $10.1M | 0.09% | −745,772−74.6% | Reduced |
| Renaissance Technologies LLC | 244,981 | $9.71M | 0.02% | +28,296+13.1% | Added |
| Goldman Sachs Group Inc | 240,435 | $9.53M | 0.00% | +42,491+21.5% | Added |
| FMR LLC | 238,561 | $9.46M | 0.00% | +150.0% | Added |
| Rafferty Asset Management, LLC | 234,625 | $9.30M | 0.03% | +154,463+192.7% | Added |
| Integral Health Asset Management, LLC | 230,000 | $9.12M | 0.89% | +230,000 | New |
| Citigroup Inc | 207,496 | $8.23M | 0.01% | +171,719+480.0% | Added |
| Walleye Capital LLC | 206,104 | $8.17M | 0.09% | −159,836−43.7% | Reduced |
| Deutsche Bank AG | 204,479 | $8.11M | 0.00% | +75,000+57.9% | Added |
| Bank of America Corp | 202,414 | $8.02M | 0.00% | +110,648+120.6% | Added |
| Silverarc Capital Management, LLC | 199,020 | $7.89M | 2.21% | −98,769−33.2% | Reduced |
| Jennison Associates LLC | 191,974 | $7.61M | 0.01% | +50,879+36.1% | Added |
| Dimensional Fund Advisors LP | 191,779 | $7.60M | 0.00% | −42,102−18.0% | Reduced |
| Jane Street Group, LLC | 177,434 | $7.03M | 0.01% | +107,981+155.5% | Added |
| ExodusPoint Capital Management, LP | 171,251 | $6.79M | 0.08% | −37,723−18.1% | Reduced |
| Qube Research & Technologies Ltd | 163,323 | $6.47M | 0.01% | −42,443−20.6% | Reduced |
| Wellington Management Group LLP | 161,145 | $6.39M | 0.00% | +51,263+46.7% | Added |
| UBS Group AG | 153,473 | $6.08M | 0.00% | +87,666+133.2% | Added |
| Citadel Advisors LLC | 142,879 | $5.66M | 0.01% | −732,378−83.7% | Reduced |
| Ensign Peak Advisors, Inc | 140,043 | $5.55M | 0.01% | +10,068+7.7% | Added |
| Federated Hermes, Inc. | 138,981 | $5.51M | 0.01% | +138,616+37,977.0% | Added |
| Hillsdale Investment Management Inc. | 133,960 | $5.31M | 0.42% | +133,960 | New |
| Tri Locum Partners LP | 120,687 | $4.78M | 1.66% | +120,687 | New |
| TD Asset Management Inc | 118,418 | $4.69M | 0.00% | +85,218+256.7% | Added |
| Exome Asset Management LLC | 117,000 | $4.64M | 3.97% | −56,500−32.6% | Reduced |
| Trexquant Investment LP | 115,776 | $4.59M | 0.09% | +61,996+115.3% | Added |
| Point72 Asset Management, L.P. | 110,700 | $4.39M | 0.01% | +110,700 | New |
| Susquehanna International Group, LLP | 109,860 | $4.35M | 0.01% | +87,085+382.4% | Added |
| Algert Global LLC | 108,841 | $4.31M | 0.17% | +80,551+284.7% | Added |
| Handelsbanken Fonder AB | 102,000 | $4.04M | 0.02% | +102,000 | New |
| Rhenman & Partners Asset Management AB | 85,500 | $3.39M | 0.32% | +85,500 | New |
| Manufacturers Life Insurance Company, The | 83,868 | $3.32M | 0.00% | +57,090+213.2% | Added |
| Baker Bros. Advisors LP | 81,578 | $3.23M | 0.04% | +81,578 | New |
| Altium Capital Management LP | 77,848 | $3.09M | 1.38% | −875−1.1% | Reduced |
| BNP Paribas Arbitrage, SA | 77,784 | $3.08M | 0.00% | −29,157−27.3% | Reduced |
| Raymond James Financial Services Advisors, Inc. | 76,508 | $3.03M | 0.00% | +76,508 | New |
| EAM Investors, LLC | 74,899 | $2.97M | 0.47% | −87,786−54.0% | Reduced |
| Boothbay Fund Management, LLC | 67,972 | $2.69M | 0.08% | −48,851−41.8% | Reduced |
| Swiss National Bank | 63,500 | $2.52M | 0.00% | +6,300+11.0% | Added |
| Rhumbline Advisers | 54,543 | $2.16M | 0.00% | +10,822+24.8% | Added |
| Cinctive Capital Management LP | 54,071 | $2.14M | 0.11% | +54,071 | New |
| Monashee Investment Management LLC | 52,546 | $2.08M | 0.25% | −22,246−29.7% | Reduced |
| Artia Global Partners LP | 51,714 | $2.05M | 0.50% | +51,714 | New |
| Moody Aldrich Partners LLC | 50,798 | $2.01M | 0.34% | +50,798 | New |
| Tudor Investment Corp Et Al | 50,729 | $2.01M | 0.02% | +50,729 | New |
| Barclays PLC | 49,170 | $1.95M | 0.00% | −31,127−38.8% | Reduced |
| Alps Advisors Inc | 46,222 | $1.83M | 0.01% | +6,631+16.7% | Added |
| Victory Capital Management Inc | 45,064 | $1.79M | 0.00% | +45,064 | New |
| Sphera Funds Management Ltd. | 44,841 | $1.78M | 0.29% | −190,000−80.9% | Reduced |
| Alliancebernstein L.P. | 41,290 | $1.64M | 0.00% | +11,250+37.5% | Added |
| AWM Investment Company, Inc. | 40,000 | $1.59M | 0.21% | 00.0% | Unchanged |
| ClariVest Asset Management LLC | 38,873 | $1.54M | 0.16% | +73+0.2% | Added |
| Capstone Investment Advisors, LLC | 38,212 | $1.51M | 0.03% | +12,923+51.1% | Added |
| UBS Asset Management Americas Inc | 37,925 | $1.50M | 0.00% | +25,916+215.8% | Added |
| Profund Advisors LLC | 36,372 | $1.44M | 0.06% | +22,934+170.7% | Added |
| Jefferies Financial Group Inc. | 35,000 | $1.39M | 0.03% | −65,152−65.1% | Reduced |
| California State Teachers Retirement System | 32,823 | $1.30M | 0.00% | +1,660+5.3% | Added |
| Credit Suisse AG | 32,211 | $1.28M | 0.00% | +5,467+20.4% | Added |
| Legal & General Group Plc | 30,901 | $1.22M | 0.00% | +4,638+17.7% | Added |
| State of Wisconsin Investment Board | 30,133 | $1.19M | 0.00% | +1,184+4.1% | Added |