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Alpine Immune Sciences, Inc.

ALPNDelisted May 20, 2024
Industry
Pharmaceutical Preparations
SEC CIK
0001626199

Alpine Immune Sciences, Inc. was delisted on May 20, 2024; its insiders filed their last Form 4 on May 20, 2024; 180 institutions reported holding it in 13F filings for Q1 2024, worth $2.56B in total; no superinvestor held it.

13F holders, Q4 2022

Institutional positions in Alpine Immune Sciences, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
64
−6 vs. Q3 2022
Shares held
40.9M
+1.47M (+3.7%) vs. Q3 2022
Total value
$300.8M
+$16.7M (+5.9%) vs. Q3 2022
New holders
8
33 more added
Sold out
14
9 more reduced

Compare with Q3 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALPN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2022: 64 institutions
Q1 2021: 48 institutionsQ2 2021: 47 institutionsQ3 2021: 44 institutionsQ4 2021: 53 institutionsQ1 2022: 56 institutionsQ2 2022: 58 institutionsQ3 2022: 70 institutionsQ4 2022: 64 institutionsQ1 2023: 61 institutionsQ2 2023: 77 institutionsQ3 2023: 88 institutionsQ4 2023: 133 institutionsQ1 2024: 180 institutionsQ2 2024: 0 institutionsQ3 2024: 0 institutionsQ4 2024: 0 institutionsQ1 2025: 0 institutionsQ2 2025: 0 institutionsQ3 2025: 0 institutionsQ4 2025: 0 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ4 2022: $300.8M
Q1 2021: $145.0MQ2 2021: $118.5MQ3 2021: $163.5MQ4 2021: $257.1MQ1 2022: $221.8MQ2 2022: $204.4MQ3 2022: $284.0MQ4 2022: $300.8MQ1 2023: $319.4MQ2 2023: $449.3MQ3 2023: $525.8MQ4 2023: $1.12BQ1 2024: $2.56BQ2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: $0Q2 2025: $0Q3 2025: $0Q4 2025: $0Q1 2026: $0Q2 2026: $0
Institutions holding ALPN and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20250$0
Q3 20250$0
Q2 20250$0
Q1 20250$0
Q4 20240$0
Q3 20240$0
Q2 20240$0
Q1 2024180$2.56B
Q4 2023133$1.12B
Q3 202388$525.8M
Q2 202377$449.3M
Q1 202361$319.4M
Q4 202264$300.8M
Q3 202270$284.0M
Q2 202258$204.4M
Q1 202256$221.8M
Q4 202153$257.1M
Q3 202144$163.5M
Q2 202147$118.5M
Q1 202148$145.0M

Institutions, Q4 2022

Shares, value and share of portfolio for each institution holding Alpine Immune Sciences, Inc.; share changes are against Q3 2022.

Institutions holding ALPN in Q4 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Decheng Capital Management III (Cayman), LLC6,708,288$49.3M18.45%00.0%Unchanged
Ra Capital Management, L.P.4,397,368$32.3M0.66%+40,736+0.9%Added
OrbiMed Advisors LLC4,081,592$30.0M0.57%00.0%Unchanged
Great Point Partners LLC3,637,718$26.7M5.53%+189,197+5.5%Added
Lynx1 Capital Management LP3,126,173$23.0M19.87%+69,753+2.3%Added
Frazier Life Sciences Management, L.P.2,985,757$21.9M1.36%00.0%Unchanged
Paradigm Biocapital Advisors LP2,317,634$17.0M2.00%+102,912+4.6%Added
Omega Fund Management, LLC2,029,580$14.9M5.03%00.0%Unchanged
BlackRock Inc.1,436,860$10.6M0.00%+509,137+54.9%Added
Vanguard Group Inc1,360,503$10.0M0.00%+237,703+21.2%Added
Commodore Capital LP1,325,000$9.74M1.47%00.0%Unchanged
Octagon Capital Advisors LP1,225,000$9.00M1.40%00.0%Unchanged
Artal Group S.A.1,193,030$8.77M0.51%00.0%Unchanged
BVF Inc1,135,940$8.35M0.35%00.0%Unchanged
Avidity Partners Management LP1,028,200$7.56M0.18%+29,600+3.0%Added
Geode Capital Management, LLC485,750$3.57M0.00%+234,246+93.1%Added
Renaissance Technologies LLC332,894$2.45M0.00%−25,800−7.2%Reduced
State Street Corp303,418$2.23M0.00%+24,436+8.8%Added
TCG Crossover Management, LLC253,069$1.86M0.33%−1,500−0.6%Reduced
Affinity Asset Advisors, LLC247,891$1.82M0.84%+137,891+125.4%Added
Sphera Funds Management Ltd.200,000$1.47M0.46%00.0%Unchanged
Northern Trust Corp191,572$1.41M0.00%+67,094+53.9%Added
Cheyne Capital Management (UK) LLP181,886$1.34M2.36%+181,886New
Dimensional Fund Advisors LP98,807$725.0K0.00%+47,437+92.3%Added
Bank of New York Mellon Corp83,591$614.4K0.00%+19,111+29.6%Added
Two Sigma Advisers, LP65,175$479.0K0.00%−3,300−4.8%Reduced
Charles Schwab Investment Management Inc64,496$474.0K0.00%+24,673+62.0%Added
Connor, Clark & Lunn Investment Management Ltd.58,308$428.6K0.00%+802+1.4%Added
Nuveen Asset Management, LLC31,729$233.0K0.00%+3,047+10.6%Added
Pura Vida Investments, LLC30,924$227.3K0.04%+30,924New
Goldman Sachs Group Inc30,489$224.1K0.00%+6,550+27.4%Added
Rhumbline Advisers26,233$193.0K0.00%+4,496+20.7%Added
Bank of America Corp23,666$173.9K0.00%+17,075+259.1%Added
Susquehanna International Group, LLP22,162$162.9K0.00%+22,162New
Citadel Advisors LLC21,204$155.8K0.00%+21,204New
Price T Rowe Associates Inc19,401$143.0K0.00%+6,786+53.8%Added
Morgan Stanley17,561$129.1K0.00%+5,999+51.9%Added
Trexquant Investment LP16,763$123.2K0.00%+6,037+56.3%Added
BNP Paribas Arbitrage, SA15,511$114.0K0.00%+8,939+136.0%Added
JPMorgan Chase & Co14,230$105.0K0.00%+3,657+34.6%Added
Hikari Power Ltd12,445$91.0K0.01%00.0%Unchanged
MetLife Investment Management12,028$88.4K0.00%+12,028New
Western Wealth Management, LLC12,000$88.2K0.01%−12,000−50.0%Reduced
American International Group, Inc.10,710$78.7K0.00%+3,295+44.4%Added
California State Teachers Retirement System9,038$66.4K0.00%+2,873+46.6%Added
Deutsche Bank AG8,155$59.9K0.00%+106+1.3%Added
Barclays PLC6,080$44.7K0.00%+5,418+818.4%Added
New York State Common Retirement Fund5,437$40.0K0.00%00.0%Unchanged
Allspring Global Investments Holdings, LLC4,453$32.7K0.00%−125,736−96.6%Reduced
Royal Bank of Canada3,155$23.0K0.00%+2,965+1,560.5%Added
Legal & General Group Plc2,473$18.2K0.00%+1,031+71.5%Added
Amalgamated Bank2,385$18.0K0.00%+355+17.5%Added
UBS Group AG2,276$16.7K0.00%+2,276New
Zurcher Kantonalbank (Zurich Cantonalbank)1,714$12.6K0.00%−331−16.2%Reduced
Metropolitan Life Insurance Co1,418$10.4K0.00%+1,418New
Tower Research Capital LLC (TRC)1,021$8.00K0.00%−583−36.3%Reduced
Ameritas Investment Partners, Inc.911$7.49K0.00%00.0%Unchanged
FMR LLC680$5.00K0.00%+478+236.6%Added
Citigroup Inc594$4.37K0.00%−25−4.0%Reduced
China Universal Asset Management Co., Ltd.467$3.43K0.00%+182+63.9%Added
Daiwa Securities Group Inc.85$1.00K0.00%00.0%Unchanged
Tradewinds Capital Management, LLC15$1100.00%00.0%Unchanged
Credit Suisse AG1$70.00%−84−98.8%Reduced
Nisa Investment Advisors, LLC12$00.00%+12New
Monashee Investment Management LLC0$00.00%−100,000−100.0%Sold out
Walleye Capital LLC0$00.00%−71,355−100.0%Sold out
Bridgeway Capital Management, LLC0$00.00%−70,611−100.0%Sold out
Alberta Investment Management Corp0$00.00%−45,906−100.0%Sold out
Caas Capital Management LP0$00.00%−45,354−100.0%Sold out
Marshall Wace, LLP0$00.00%−45,077−100.0%Sold out
Two Sigma Investments, LP0$00.00%−21,924−100.0%Sold out
Jacobs Levy Equity Management, Inc0$00.00%−17,753−100.0%Sold out
Jump Financial, LLC0$00.00%−10,013−100.0%Sold out
BIT Capital GmbH0$00.00%−6,000−100.0%Sold out
STRS Ohio0$00.00%−5,500−100.0%Sold out
Public Employees Retirement System of Ohio0$00.00%−4,879−100.0%Sold out
Wells Fargo & Company0$00.00%−127−100.0%Sold out
Simplex Trading, LLC0$00.00%−129−100.0%Sold out