Ionis Pharmaceuticals Inc
IONS- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
近 90 天，Ionis Pharmaceuticals Inc 內部人申報 1 筆公開市場買進、4 筆賣出；2026 年第 2 季末有 515 家機構在 13F 申報持有，市值合計 $142.6 億；大師中只有方舟投資持有。
2021 年第 3 季 13F 持有人
Ionis Pharmaceuticals Inc 在 2021/9/30 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 326
- 較 2021 年第 2 季 −9 家
- 持有股數
- 1.22 億
- 較 2021 年第 2 季 −253.5 萬 (−2.0%)
- 總市值
- $40.8 億
- 較 2021 年第 2 季 −$8.72 億 (−17.6%)
- 新進機構
- 38
- 另有 108 家加碼
- 清倉機構
- 47
- 另有 103 家減碼
另有 3 家機構在 2021 年第 2 季持有、還沒有申報 2021 年第 3 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 IONS 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 515 | $142.6 億 |
| 2026 年第 1 季 | 497 | $129.7 億 |
| 2025 年第 4 季 | 494 | $134.6 億 |
| 2025 年第 3 季 | 437 | $110.1 億 |
| 2025 年第 2 季 | 363 | $66.7 億 |
| 2025 年第 1 季 | 344 | $50.3 億 |
| 2024 年第 4 季 | 356 | $56.1 億 |
| 2024 年第 3 季 | 354 | $63.1 億 |
| 2024 年第 2 季 | 357 | $68.3 億 |
| 2024 年第 1 季 | 361 | $61.7 億 |
| 2023 年第 4 季 | 365 | $72.1 億 |
| 2023 年第 3 季 | 312 | $63.5 億 |
| 2023 年第 2 季 | 305 | $56.0 億 |
| 2023 年第 1 季 | 315 | $46.9 億 |
| 2022 年第 4 季 | 339 | $49.3 億 |
| 2022 年第 3 季 | 350 | $55.9 億 |
| 2022 年第 2 季 | 351 | $46.1 億 |
| 2022 年第 1 季 | 333 | $46.3 億 |
| 2021 年第 4 季 | 341 | $37.5 億 |
| 2021 年第 3 季 | 326 | $40.8 億 |
| 2021 年第 2 季 | 338 | $49.6 億 |
| 2021 年第 1 季 | 365 | $55.5 億 |
2021 年第 3 季持有機構
每家機構持有 Ionis Pharmaceuticals Inc 的股數、市值與佔組合比重；股數變化跟 2021 年第 2 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Simplex Trading, LLC | 22,512 | $90.1 萬 | 0.03% | +1,158+5.4% | 加碼 |
| Kestra Advisory Services, LLC | 27,924 | $93.7 萬 | 0.01% | +5,078+22.2% | 加碼 |
| Truist Financial Corp | 30,977 | $103.9 萬 | 0.00% | +5,876+23.4% | 加碼 |
| Group One Trading, L.P. | 31,533 | $105.8 萬 | 0.02% | +30.0% | 加碼 |
| Employees Retirement System of Texas | 32,409 | $108.7 萬 | 0.01% | 00.0% | 不變 |
| Macquarie Group Ltd | 32,428 | $108.8 萬 | 0.00% | 00.0% | 不變 |
| ProShare Advisors LLC | 33,499 | $112.4 萬 | 0.00% | +3,076+10.1% | 加碼 |
| Janney Montgomery Scott LLC | 34,153 | $114.5 萬 | 0.00% | −4,493−11.6% | 減碼 |
| Arizona State Retirement System | 34,557 | $115.9 萬 | 0.01% | +96+0.3% | 加碼 |
| Storebrand Asset Management AS | 34,666 | $116.3 萬 | 0.01% | −756−2.1% | 減碼 |
| Connor, Clark & Lunn Investment Management Ltd. | 35,536 | $119.2 萬 | 0.01% | +35,536 | 新進 |
| First Foundation Advisors | 35,746 | $119.9 萬 | 0.04% | +1,297+3.8% | 加碼 |
| Commonwealth Equity Services, LLC | 38,118 | $127.8 萬 | 0.00% | +12,388+48.1% | 加碼 |
| Gateway Investment Advisers LLC | 38,132 | $127.9 萬 | 0.01% | +532+1.4% | 加碼 |
| Capital Counsel LLC | 40,580 | $136.1 萬 | 0.07% | 00.0% | 不變 |
| Arrowstreet Capital, Limited Partnership | 41,100 | $137.8 萬 | 0.00% | −51,800−55.8% | 減碼 |
| NJ State Employees Deferred Compensation Plan | 42,000 | $140.8 萬 | 0.19% | 00.0% | 不變 |
| Principal Financial Group Inc | 42,685 | $143.2 萬 | 0.00% | −5,285−11.0% | 減碼 |
| Voya Investment Management LLC | 42,700 | $143.2 萬 | 0.00% | −719−1.7% | 減碼 |
| Private Advisor Group, LLC | 44,105 | $148.0 萬 | 0.01% | +20,664+88.2% | 加碼 |
| Jefferies Group LLC | 44,137 | $148.0 萬 | 0.04% | −22,567−33.8% | 減碼 |
| International Biotechnology Trust PLC | 44,781 | $150.2 萬 | 0.37% | −137,000−75.4% | 減碼 |
| Raymond James Financial Services Advisors, Inc. | 46,156 | $154.8 萬 | 0.00% | +1,325+3.0% | 加碼 |
| Treasurer of the State of North Carolina | 50,516 | $169.4 萬 | 0.01% | +1,709+3.5% | 加碼 |
| Deutsche Bank AG | 50,946 | $170.9 萬 | 0.00% | −183,440−78.3% | 減碼 |
| Erste Asset Management GmbH | 51,300 | $172.3 萬 | 0.03% | 00.0% | 不變 |
| AlphaCrest Capital Management LLC | 52,084 | $174.7 萬 | 0.09% | +32,724+169.0% | 加碼 |
| Ergoteles LLC | 52,872 | $177.3 萬 | 0.07% | −123,381−70.0% | 減碼 |
| AXA S.A. | 57,200 | $191.8 萬 | 0.01% | +57,200 | 新進 |
| Guggenheim Capital LLC | 62,637 | $210.1 萬 | 0.01% | +6,501+11.6% | 加碼 |
| Jane Street Group, LLC | 64,476 | $216.3 萬 | 0.01% | +18,059+38.9% | 加碼 |
| Alliancebernstein L.P. | 68,451 | $229.6 萬 | 0.00% | −1,352−1.9% | 減碼 |
| Rhenman & Partners Asset Management AB | 75,000 | $251.6 萬 | 0.18% | 00.0% | 不變 |
| PFS Investments Inc. | 76,842 | $268.0 萬 | 0.06% | +1,127+1.5% | 加碼 |
| LPL Financial LLC | 83,615 | $280.4 萬 | 0.00% | +24,299+41.0% | 加碼 |
| Sabby Management, LLC | 84,600 | $283.7 萬 | 0.62% | +6,600+8.5% | 加碼 |
| Cubist Systematic Strategies, LLC | 86,754 | $291.0 萬 | 0.04% | −91,388−51.3% | 減碼 |
| State of New Jersey Common Pension Fund D | 87,216 | $292.5 萬 | 0.01% | +471+0.5% | 加碼 |
| Public Employees Retirement System of Ohio | 87,444 | $293.3 萬 | 0.01% | +7,390+9.2% | 加碼 |
| Rafferty Asset Management, LLC | 96,737 | $324.5 萬 | 0.02% | +27,965+40.7% | 加碼 |
| Renaissance Technologies LLC | 97,714 | $327.7 萬 | 0.00% | −678,700−87.4% | 減碼 |
| Envestnet Asset Management Inc | 102,422 | $343.5 萬 | 0.00% | +6,702+7.0% | 加碼 |
| Wolverine Trading, LLC | 106,878 | $358.9 萬 | 0.07% | −4,070−3.7% | 減碼 |
| DekaBank Deutsche Girozentrale | 107,576 | $361.4 萬 | 0.01% | 00.0% | 不變 |
| Caption Management, LLC | 120,993 | $405.8 萬 | 0.27% | +24,986+26.0% | 加碼 |
| Citigroup Inc | 121,064 | $406.0 萬 | 0.00% | −121,059−50.0% | 減碼 |
| Davenport & Co LLC | 122,303 | $410.0 萬 | 0.03% | +5,340+4.6% | 加碼 |
| D. E. Shaw & Co., Inc. | 126,106 | $423.0 萬 | 0.01% | +51,440+68.9% | 加碼 |
| HRT Financial LP | 128,087 | $429.6 萬 | 0.03% | +128,087 | 新進 |
| UBS Group AG | 132,812 | $445.5 萬 | 0.00% | −22,317−14.4% | 減碼 |
| Pictet Asset Management SA | 135,696 | $455.1 萬 | 0.01% | +135,696 | 新進 |
| Peregrine Capital Management LLC | 135,787 | $455.4 萬 | 0.09% | −26,741−16.5% | 減碼 |
| Parkman Healthcare Partners LLC | 136,380 | $457.4 萬 | 1.16% | 00.0% | 不變 |
| Rhumbline Advisers | 138,363 | $464.1 萬 | 0.01% | −1,222−0.9% | 減碼 |
| Invesco Ltd. | 141,355 | $474.2 萬 | 0.00% | −199,258−58.5% | 減碼 |
| Balyasny Asset Management LLC | 142,015 | $476.3 萬 | 0.02% | −121,271−46.1% | 減碼 |
| BLB&B Advisors, LLC | 156,200 | $523.9 萬 | 0.35% | −1,290−0.8% | 減碼 |
| State Board of Administration of Florida Retirement System | 161,938 | $543.1 萬 | 0.01% | −2,170−1.3% | 減碼 |
| Sonora Investment Management, LLC | 163,703 | $549.1 萬 | 0.69% | −4,962−2.9% | 減碼 |
| Legal & General Group Plc | 167,421 | $561.6 萬 | 0.00% | +41,538+33.0% | 加碼 |
| Tocqueville Asset Management L.P. | 168,530 | $565.2 萬 | 0.08% | −3,670−2.1% | 減碼 |
| Squarepoint Ops LLC | 169,865 | $569.7 萬 | 0.04% | +122,120+255.8% | 加碼 |
| Susquehanna International Group, LLP | 174,166 | $584.2 萬 | 0.01% | −206,300−54.2% | 減碼 |
| Majedie Asset Management Ltd | 175,508 | $588.8 萬 | 0.45% | −8,954−4.9% | 減碼 |
| UBS Asset Management Americas Inc | 180,665 | $606.0 萬 | 0.00% | +4,324+2.5% | 加碼 |
| Credit Suisse AG | 182,662 | $612.6 萬 | 0.00% | +23,477+14.7% | 加碼 |
| American Century Companies Inc | 199,346 | $668.6 萬 | 0.00% | −26,834−11.9% | 減碼 |
| Tudor Investment Corp Et Al | 201,613 | $676.2 萬 | 0.14% | +101,727+101.8% | 加碼 |
| Morningstar Investment Services LLC | 214,141 | $721.2 萬 | 0.09% | +4,034+1.9% | 加碼 |
| Point72 Asset Management, L.P. | 219,300 | $735.5 萬 | 0.03% | −757,600−77.6% | 減碼 |
| California State Teachers Retirement System | 225,991 | $758.0 萬 | 0.01% | −17,731−7.3% | 減碼 |
| Parametric Portfolio Associates LLC | 231,506 | $776.5 萬 | 0.00% | +11,294+5.1% | 加碼 |
| Russell Investments Group, Ltd. | 231,865 | $777.3 萬 | 0.01% | +10,311+4.7% | 加碼 |
| New York State Common Retirement Fund | 241,159 | $808.8 萬 | 0.01% | 00.0% | 不變 |
| Bank of Montreal | 249,704 | $849.3 萬 | 0.00% | −131,781−34.5% | 減碼 |
| Sector Gamma AS | 263,870 | $885.0 萬 | 1.77% | +382+0.1% | 加碼 |
| Hudson Bay Capital Management LP | 265,000 | $888.8 萬 | 0.13% | +80,000+43.2% | 加碼 |
| Swiss National Bank | 279,900 | $938.8 萬 | 0.01% | 00.0% | 不變 |
| Millennium Management LLC | 282,854 | $948.7 萬 | 0.01% | −512,988−64.5% | 減碼 |
| California Public Employees Retirement System | 288,128 | $966.4 萬 | 0.01% | −32,552−10.2% | 減碼 |
| Sicart Associates LLC | 291,254 | $976.9 萬 | 2.66% | −77,155−20.9% | 減碼 |
| Raymond James & Associates | 301,449 | $1,011 萬 | 0.01% | +7,511+2.6% | 加碼 |
| Baillie Gifford & Co | 302,003 | $1,013 萬 | 0.01% | +30,607+11.3% | 加碼 |
| Dowling & Yahnke LLC | 302,521 | $1,015 萬 | 0.56% | −629−0.2% | 減碼 |
| Two Sigma Investments, LP | 314,134 | $1,054 萬 | 0.03% | +7,646+2.5% | 加碼 |
| Tekla Capital Management LLC | 322,521 | $1,082 萬 | 0.35% | 00.0% | 不變 |
| Barclays PLC | 330,291 | $1,108 萬 | 0.01% | −33,705−9.3% | 減碼 |
| Dimensional Fund Advisors LP | 355,839 | $1,194 萬 | 0.00% | −54,378−13.3% | 減碼 |
| Nomura Holdings Inc | 376,748 | $1,260 萬 | 0.10% | −980−0.3% | 減碼 |
| Stifel Financial Corp | 376,219 | $1,262 萬 | 0.02% | −1,466−0.4% | 減碼 |
| Woodline Partners LP | 405,461 | $1,360 萬 | 0.23% | −558,327−57.9% | 減碼 |
| TD Asset Management Inc | 421,964 | $1,415 萬 | 0.01% | +1000.0% | 加碼 |
| Two Sigma Advisers, LP | 432,211 | $1,450 萬 | 0.04% | −93,600−17.8% | 減碼 |
| Altrinsic Global Advisors LLC | 444,887 | $1,492 萬 | 0.45% | −11,339−2.5% | 減碼 |
| Eversept Partners, LP | 450,501 | $1,511 萬 | 1.21% | +8,501+1.9% | 加碼 |
| Royal Bank of Canada | 489,561 | $1,642 萬 | 0.00% | +4,595+0.9% | 加碼 |
| Morgan Stanley | 497,936 | $1,670 萬 | 0.00% | −29,673−5.6% | 減碼 |
| Pinnacle Associates Ltd | 543,226 | $1,822 萬 | 0.34% | +1,884+0.3% | 加碼 |
| Bank of New York Mellon Corp | 560,566 | $1,880 萬 | 0.00% | +20,037+3.7% | 加碼 |
| Goldman Sachs Group Inc | 601,836 | $2,019 萬 | 0.01% | −77,593−11.4% | 減碼 |