Ionis Pharmaceuticals Inc
IONS- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
近 90 天，Ionis Pharmaceuticals Inc 內部人申報 1 筆公開市場買進、4 筆賣出；2026 年第 2 季末有 515 家機構在 13F 申報持有，市值合計 $142.6 億；大師中只有方舟投資持有。
2021 年第 2 季 13F 持有人
Ionis Pharmaceuticals Inc 在 2021/6/30 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 338
- 較 2021 年第 1 季 −24 家
- 持有股數
- 1.24 億
- 較 2021 年第 1 季 +261.9 萬 (+2.2%)
- 總市值
- $49.6 億
- 較 2021 年第 1 季 −$5.16 億 (−9.4%)
- 新進機構
- 51
- 另有 116 家加碼
- 清倉機構
- 75
- 另有 103 家減碼
另有 3 家機構在 2021 年第 1 季持有、還沒有申報 2021 年第 2 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 IONS 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 515 | $142.6 億 |
| 2026 年第 1 季 | 497 | $129.7 億 |
| 2025 年第 4 季 | 494 | $134.6 億 |
| 2025 年第 3 季 | 437 | $110.1 億 |
| 2025 年第 2 季 | 363 | $66.7 億 |
| 2025 年第 1 季 | 344 | $50.3 億 |
| 2024 年第 4 季 | 356 | $56.1 億 |
| 2024 年第 3 季 | 354 | $63.1 億 |
| 2024 年第 2 季 | 357 | $68.3 億 |
| 2024 年第 1 季 | 361 | $61.7 億 |
| 2023 年第 4 季 | 365 | $72.1 億 |
| 2023 年第 3 季 | 312 | $63.5 億 |
| 2023 年第 2 季 | 305 | $56.0 億 |
| 2023 年第 1 季 | 315 | $46.9 億 |
| 2022 年第 4 季 | 339 | $49.3 億 |
| 2022 年第 3 季 | 350 | $55.9 億 |
| 2022 年第 2 季 | 351 | $46.1 億 |
| 2022 年第 1 季 | 333 | $46.3 億 |
| 2021 年第 4 季 | 341 | $37.5 億 |
| 2021 年第 3 季 | 326 | $40.8 億 |
| 2021 年第 2 季 | 338 | $49.6 億 |
| 2021 年第 1 季 | 365 | $55.5 億 |
2021 年第 2 季持有機構
每家機構持有 Ionis Pharmaceuticals Inc 的股數、市值與佔組合比重；股數變化跟 2021 年第 1 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Handelsbanken Fonder AB | 24,411 | $97.4 萬 | 0.01% | +1,400+6.1% | 加碼 |
| Truist Financial Corp | 25,101 | $100.1 萬 | 0.00% | +3,437+15.9% | 加碼 |
| Stephens Inc | 25,638 | $102.3 萬 | 0.02% | +482+1.9% | 加碼 |
| Commonwealth Equity Services, LLC | 25,730 | $102.6 萬 | 0.00% | +7,594+41.9% | 加碼 |
| Utah Retirement Systems | 26,709 | $106.5 萬 | 0.01% | +1,600+6.4% | 加碼 |
| Amalgamated Bank | 26,933 | $107.4 萬 | 0.01% | +7,267+37.0% | 加碼 |
| Eaton Vance Management | 27,074 | $108.0 萬 | 0.00% | +604+2.3% | 加碼 |
| Cowen and Company, LLC | 27,708 | $110.5 萬 | 0.06% | +20,627+291.3% | 加碼 |
| Twin Tree Management, LP | 29,382 | $117.2 萬 | 0.04% | +29,382 | 新進 |
| ProShare Advisors LLC | 30,423 | $121.4 萬 | 0.00% | +8,288+37.4% | 加碼 |
| Edgestream Partners, L.P. | 31,262 | $124.7 萬 | 0.07% | +31,262 | 新進 |
| Group One Trading, L.P. | 31,530 | $125.8 萬 | 0.02% | +2,619+9.1% | 加碼 |
| Skandinaviska Enskilda Banken AB (publ) | 32,293 | $128.8 萬 | 0.01% | −22,200−40.7% | 減碼 |
| Employees Retirement System of Texas | 32,409 | $129.3 萬 | 0.02% | 00.0% | 不變 |
| Macquarie Group Ltd | 32,428 | $129.4 萬 | 0.00% | +1,971+6.5% | 加碼 |
| Great West Life Assurance Co | 33,166 | $132.3 萬 | 0.00% | −24,310−42.3% | 減碼 |
| Seeyond | 33,852 | $135.0 萬 | 0.13% | +151+0.4% | 加碼 |
| First Foundation Advisors | 34,449 | $137.4 萬 | 0.05% | +4,386+14.6% | 加碼 |
| Arizona State Retirement System | 34,461 | $137.5 萬 | 0.01% | −3,838−10.0% | 減碼 |
| Storebrand Asset Management AS | 35,422 | $141.3 萬 | 0.01% | −1,931−5.2% | 減碼 |
| Gateway Investment Advisers LLC | 37,600 | $150.0 萬 | 0.02% | 00.0% | 不變 |
| Janney Montgomery Scott LLC | 38,646 | $154.2 萬 | 0.01% | +1,834+5.0% | 加碼 |
| Capital Counsel LLC | 40,580 | $161.9 萬 | 0.08% | −1,500−3.6% | 減碼 |
| NJ State Employees Deferred Compensation Plan | 42,000 | $167.6 萬 | 0.22% | 00.0% | 不變 |
| Voya Investment Management LLC | 43,419 | $173.2 萬 | 0.00% | +12,708+41.4% | 加碼 |
| Raymond James Financial Services Advisors, Inc. | 44,831 | $178.8 萬 | 0.00% | +9,302+26.2% | 加碼 |
| Jane Street Group, LLC | 46,417 | $185.1 萬 | 0.00% | +13,554+41.2% | 加碼 |
| Squarepoint Ops LLC | 47,745 | $190.5 萬 | 0.01% | +28,158+143.8% | 加碼 |
| Principal Financial Group Inc | 47,970 | $191.3 萬 | 0.00% | +3,559+8.0% | 加碼 |
| Treasurer of the State of North Carolina | 48,807 | $194.7 萬 | 0.01% | +890+1.9% | 加碼 |
| Erste Asset Management GmbH | 51,300 | $202.9 萬 | 0.04% | +16,800+48.7% | 加碼 |
| Guggenheim Capital LLC | 56,136 | $223.9 萬 | 0.01% | −15,256−21.4% | 減碼 |
| LPL Financial LLC | 59,316 | $236.6 萬 | 0.00% | +4,033+7.3% | 加碼 |
| Jump Financial, LLC | 62,400 | $248.9 萬 | 0.24% | +62,400 | 新進 |
| Jefferies Group LLC | 66,704 | $266.1 萬 | 0.05% | +46,577+231.4% | 加碼 |
| Rafferty Asset Management, LLC | 68,772 | $274.3 萬 | 0.02% | +5,888+9.4% | 加碼 |
| Alliancebernstein L.P. | 69,803 | $278.4 萬 | 0.00% | −7,497−9.7% | 減碼 |
| SG3 Management, LLC | 72,300 | $288.4 萬 | 1.23% | +52,300+261.5% | 加碼 |
| PFS Investments Inc. | 75,715 | $294.3 萬 | 0.07% | +5,211+7.4% | 加碼 |
| D. E. Shaw & Co., Inc. | 74,666 | $297.8 萬 | 0.00% | +66,560+821.1% | 加碼 |
| Rhenman & Partners Asset Management AB | 75,000 | $299.2 萬 | 0.20% | 00.0% | 不變 |
| Sabby Management, LLC | 78,000 | $311.1 萬 | 0.67% | +23,312+42.6% | 加碼 |
| Public Employees Retirement System of Ohio | 80,054 | $319.3 萬 | 0.01% | +10,669+15.4% | 加碼 |
| State of New Jersey Common Pension Fund D | 86,745 | $346.0 萬 | 0.01% | +1,822+2.1% | 加碼 |
| Susquehanna Fundamental Investments, LLC | 88,273 | $352.1 萬 | 0.06% | +33,469+61.1% | 加碼 |
| Arrowstreet Capital, Limited Partnership | 92,900 | $370.6 萬 | 0.00% | +92,900 | 新進 |
| Envestnet Asset Management Inc | 95,720 | $381.8 萬 | 0.00% | +13,400+16.3% | 加碼 |
| Caption Management, LLC | 96,007 | $382.9 萬 | 0.34% | +96,007 | 新進 |
| Tudor Investment Corp Et Al | 99,886 | $398.4 萬 | 0.08% | +99,886 | 新進 |
| DekaBank Deutsche Girozentrale | 107,576 | $426.5 萬 | 0.01% | −9,819−8.4% | 減碼 |
| Wolverine Trading, LLC | 110,948 | $438.8 萬 | 0.12% | +1,337+1.2% | 加碼 |
| Davenport & Co LLC | 116,963 | $466.3 萬 | 0.04% | −7,775−6.2% | 減碼 |
| Thrivent Financial for Lutherans | 123,367 | $492.1 萬 | 0.01% | +2,054+1.7% | 加碼 |
| Legal & General Group Plc | 125,883 | $502.1 萬 | 0.00% | −294,494−70.1% | 減碼 |
| Pictet Asset Management Ltd | 134,324 | $535.8 萬 | 0.01% | +85,324+174.1% | 加碼 |
| Parkman Healthcare Partners LLC | 136,380 | $544.0 萬 | 1.19% | +30,583+28.9% | 加碼 |
| Rhumbline Advisers | 139,585 | $556.8 萬 | 0.01% | −4,821−3.3% | 減碼 |
| PDT Partners, LLC | 141,925 | $566.1 萬 | 0.37% | +141,925 | 新進 |
| Van Eck Associates Corp | 147,383 | $587.9 萬 | 0.01% | −22,609−13.3% | 減碼 |
| UBS Group AG | 155,129 | $618.8 萬 | 0.00% | +126,067+433.8% | 加碼 |
| BLB&B Advisors, LLC | 157,490 | $628.2 萬 | 0.45% | +870+0.6% | 加碼 |
| Credit Suisse AG | 159,185 | $635.0 萬 | 0.00% | +26,191+19.7% | 加碼 |
| Peregrine Capital Management LLC | 162,528 | $648.3 萬 | 0.12% | −9,820−5.7% | 減碼 |
| State Board of Administration of Florida Retirement System | 164,108 | $654.6 萬 | 0.01% | −4,865−2.9% | 減碼 |
| Sonora Investment Management, LLC | 168,665 | $672.8 萬 | 0.88% | +4,742+2.9% | 加碼 |
| Tocqueville Asset Management L.P. | 172,200 | $686.9 萬 | 0.10% | −73,292−29.9% | 減碼 |
| Ergoteles LLC | 176,253 | $703.1 萬 | 0.16% | +176,253 | 新進 |
| UBS Asset Management Americas Inc | 176,341 | $703.4 萬 | 0.00% | −228,183−56.4% | 減碼 |
| Marshall Wace, LLP | 176,820 | $705.4 萬 | 0.04% | +176,820 | 新進 |
| Cubist Systematic Strategies, LLC | 178,142 | $710.6 萬 | 0.08% | +178,142 | 新進 |
| International Biotechnology Trust PLC | 181,781 | $725.1 萬 | 1.93% | −152,000−45.5% | 減碼 |
| Majedie Asset Management Ltd | 184,462 | $736.1 萬 | 0.48% | +62,763+51.6% | 加碼 |
| Hudson Bay Capital Management LP | 185,000 | $738.0 萬 | 0.09% | +54,600+41.9% | 加碼 |
| Morningstar Investment Services LLC | 210,107 | $831.0 萬 | 0.10% | +7,400+3.7% | 加碼 |
| Parametric Portfolio Associates LLC | 220,212 | $878.4 萬 | 0.00% | −1,589−0.7% | 減碼 |
| Russell Investments Group, Ltd. | 221,554 | $883.5 萬 | 0.01% | +190,623+616.3% | 加碼 |
| American Century Companies Inc | 226,180 | $902.2 萬 | 0.01% | −716,498−76.0% | 減碼 |
| Deutsche Bank AG | 234,386 | $935.0 萬 | 0.00% | +73,819+46.0% | 加碼 |
| New York State Common Retirement Fund | 241,159 | $962.0 萬 | 0.01% | +42,928+21.7% | 加碼 |
| Citigroup Inc | 242,123 | $965.9 萬 | 0.01% | +7,103+3.0% | 加碼 |
| California State Teachers Retirement System | 243,722 | $972.2 萬 | 0.01% | −1,361−0.6% | 減碼 |
| Worldquant Millennium Advisors LLC | 251,075 | $1,002 萬 | 0.22% | +251,075 | 新進 |
| Balyasny Asset Management LLC | 263,286 | $1,050 萬 | 0.06% | +263,286 | 新進 |
| Sector Gamma AS | 263,488 | $1,051 萬 | 1.86% | −190,662−42.0% | 減碼 |
| Baillie Gifford & Co | 271,396 | $1,083 萬 | 0.01% | +33,437+14.1% | 加碼 |
| Swiss National Bank | 279,900 | $1,117 萬 | 0.01% | −230,459−45.2% | 減碼 |
| Bank Julius Baer & Co. Ltd, Zurich | 288,844 | $1,152 萬 | 0.07% | +917+0.3% | 加碼 |
| Raymond James & Associates | 293,938 | $1,173 萬 | 0.01% | −8,137−2.7% | 減碼 |
| Dowling & Yahnke LLC | 303,150 | $1,209 萬 | 0.69% | −700.0% | 減碼 |
| Two Sigma Investments, LP | 306,488 | $1,223 萬 | 0.03% | +120,768+65.0% | 加碼 |
| California Public Employees Retirement System | 320,680 | $1,279 萬 | 0.01% | +4,103+1.3% | 加碼 |
| Tekla Capital Management LLC | 322,521 | $1,287 萬 | 0.42% | +106,150+49.1% | 加碼 |
| Invesco Ltd. | 340,613 | $1,359 萬 | 0.00% | −2,018,821−85.6% | 減碼 |
| Barclays PLC | 363,996 | $1,452 萬 | 0.01% | +265,225+268.5% | 加碼 |
| Sicart Associates LLC | 368,409 | $1,470 萬 | 3.50% | −1,889−0.5% | 減碼 |
| Nomura Holdings Inc | 377,728 | $1,505 萬 | 0.12% | +377,728 | 新進 |
| Stifel Financial Corp | 377,685 | $1,507 萬 | 0.02% | −2,713−0.7% | 減碼 |
| Bank of Montreal | 381,485 | $1,511 萬 | 0.01% | +59,255+18.4% | 加碼 |
| Susquehanna International Group, LLP | 380,466 | $1,518 萬 | 0.02% | +292,195+331.0% | 加碼 |
| TD Asset Management Inc | 421,864 | $1,567 萬 | 0.02% | −2,715−0.6% | 減碼 |