Zymeworks Inc.
ZYME- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001937653
No open-market purchases or sales by Zymeworks Inc. insiders were filed in the last 90 days; 202 institutions reported holding it in 13F filings for Q2 2026, worth $1.79B in total; no superinvestor holds it.
13F holders, Q2 2025
Institutional positions in Zymeworks Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 182
- −2 vs. Q1 2025
- Shares held
- 75.6M
- +5.10M (+7.2%) vs. Q1 2025
- Total value
- $949.0M
- +$109.0M (+13.0%) vs. Q1 2025
- New holders
- 28
- 63 more added
- Sold out
- 30
- 55 more reduced
2 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ZYME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 202 | $1.79B |
| Q1 2026 | 212 | $1.76B |
| Q4 2025 | 210 | $1.88B |
| Q3 2025 | 184 | $1.26B |
| Q2 2025 | 182 | $949.0M |
| Q1 2025 | 186 | $840.9M |
| Q4 2024 | 174 | $973.2M |
| Q3 2024 | 163 | $834.7M |
| Q2 2024 | 164 | $580.6M |
| Q1 2024 | 171 | $713.0M |
| Q4 2023 | 157 | $674.0M |
| Q3 2023 | 140 | $395.5M |
| Q2 2023 | 137 | $547.9M |
| Q1 2023 | 116 | $512.6M |
| Q4 2022 | 96 | $449.9M |
| Q3 2022 | 91 | $293.7M |
| Q2 2022 | 114 | $253.3M |
| Q1 2022 | 120 | $327.3M |
| Q4 2021 | 114 | $693.9M |
| Q3 2021 | 123 | $1.07B |
| Q2 2021 | 109 | $1.20B |
| Q1 2021 | 125 | $1.12B |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Zymeworks Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| EcoR1 Capital, LLC | 22,970,388 | $288.3M | 17.11% | +5,710,840+33.1% | Added |
| Rubric Capital Management LP | 4,710,551 | $59.1M | 0.95% | +372,107+8.6% | Added |
| BVF Inc | 4,308,935 | $54.1M | 1.93% | 00.0% | Unchanged |
| Morgan Stanley | 4,177,614 | $52.4M | 0.00% | +104,151+2.6% | Added |
| Redmile Group, LLC | 4,150,627 | $52.1M | 5.54% | −638,318−13.3% | Reduced |
| BlackRock, Inc. | 3,794,272 | $47.6M | 0.00% | −295,149−7.2% | Reduced |
| Vanguard Group Inc | 2,464,693 | $30.9M | 0.00% | +697,652+39.5% | Added |
| UBS Asset Management Americas Inc | 2,459,513 | $30.9M | 0.01% | −1,420,432−36.6% | Reduced |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 2,039,656 | $25.6M | 0.06% | −158,223−7.2% | Reduced |
| Blackstone Group Inc. | 1,656,790 | $20.8M | 0.09% | +274,203+19.8% | Added |
| Deutsche Bank AG | 1,544,763 | $19.4M | 0.01% | −7,849−0.5% | Reduced |
| Prosight Management, LP | 1,309,904 | $16.4M | 4.01% | +352,675+36.8% | Added |
| Perceptive Advisors LLC | 1,275,274 | $16.0M | 0.60% | −589,398−31.6% | Reduced |
| Dimensional Fund Advisors LP | 1,192,432 | $15.0M | 0.00% | +112,974+10.5% | Added |
| Vestal Point Capital, LP | 1,150,000 | $14.4M | 0.76% | +650,000+130.0% | Added |
| Nextech Invest, Ltd. | 1,113,946 | $14.0M | 2.65% | 00.0% | Unchanged |
| Tang Capital Management LLC | 1,100,000 | $13.8M | 0.70% | 00.0% | Unchanged |
| State Street Corp | 1,088,459 | $13.7M | 0.00% | +3,326+0.3% | Added |
| Geode Capital Management, LLC | 705,364 | $8.85M | 0.00% | +3290.0% | Added |
| Nuveen, LLC | 654,916 | $8.22M | 0.00% | +456,104+229.4% | Added |
| Renaissance Technologies LLC | 533,300 | $6.69M | 0.01% | +82,700+18.4% | Added |
| Assenagon Asset Management S.A. | 492,780 | $6.18M | 0.01% | −2,287−0.5% | Reduced |
| Adage Capital Partners GP, L.L.C. | 476,000 | $5.97M | 0.01% | +476,000 | New |
| JPMorgan Chase & Co | 441,690 | $5.54M | 0.00% | +403,281+1,050.0% | Added |
| Goldman Sachs Group Inc | 428,857 | $5.38M | 0.00% | +228,810+114.4% | Added |
| Granahan Investment Management Inc | 380,783 | $4.78M | 0.19% | −26,806−6.6% | Reduced |
| Jupiter Asset Management Ltd | 369,499 | $4.64M | 0.04% | 00.0% | Unchanged |
| Northern Trust Corp | 349,799 | $4.39M | 0.00% | −37,124−9.6% | Reduced |
| Samsara BioCapital, LLC | 310,300 | $3.89M | 0.80% | −356,367−53.5% | Reduced |
| Schroder Investment Management Group | 304,666 | $3.80M | 0.00% | −17,283−5.4% | Reduced |
| Silvercrest Asset Management Group LLC | 280,726 | $3.52M | 0.02% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 259,137 | $3.25M | 0.00% | −92,024−26.2% | Reduced |
| D. E. Shaw & Co., Inc. | 255,291 | $3.20M | 0.00% | +192,192+304.6% | Added |
| UBS Group AG | 251,510 | $3.16M | 0.00% | +37,210+17.4% | Added |
| Citadel Advisors LLC | 246,155 | $3.09M | 0.00% | +65,485+36.2% | Added |
| Platinum Investment Management Ltd | 238,391 | $2.99M | 0.20% | −40,267−14.5% | Reduced |
| Trexquant Investment LP | 220,982 | $2.77M | 0.03% | +173+0.1% | Added |
| Opaleye Management Inc. | 210,000 | $2.64M | 0.53% | +35,000+20.0% | Added |
| Picton Mahoney Asset Management | 207,602 | $2.60M | 0.04% | −427−0.2% | Reduced |
| Hillsdale Investment Management Inc. | 205,022 | $2.57M | 0.09% | −31,903−13.5% | Reduced |
| Norges Bank | 201,700 | $2.53M | 0.00% | 00.0% | Unchanged |
| Tejara Capital Ltd | 200,150 | $2.51M | 1.16% | +10,741+5.7% | Added |
| Federated Hermes, Inc. | 182,270 | $2.29M | 0.00% | +358+0.2% | Added |
| Wellington Management Group LLP | 180,690 | $2.27M | 0.00% | −1,556−0.9% | Reduced |
| AXA S.A. | 175,121 | $2.20M | 0.01% | +175,121 | New |
| Wells Fargo & Company | 166,428 | $2.09M | 0.00% | +66,119+65.9% | Added |
| AQR Capital Management LLC | 166,143 | $2.09M | 0.00% | +117,658+242.7% | Added |
| Citigroup Inc | 155,998 | $1.96M | 0.00% | +114,800+278.7% | Added |
| Squarepoint Ops LLC | 155,599 | $1.95M | 0.00% | +91,997+144.6% | Added |
| Kennedy Capital Management, Inc. | 146,954 | $1.84M | 0.04% | +10,635+7.8% | Added |
| Bank of New York Mellon Corp | 133,090 | $1.67M | 0.00% | +12,363+10.2% | Added |
| Raymond James Financial Inc | 124,435 | $1.56M | 0.00% | +7,724+6.6% | Added |
| Charles Schwab Investment Management Inc | 124,204 | $1.56M | 0.00% | −9,435−7.1% | Reduced |
| Barclays PLC | 122,820 | $1.54M | 0.00% | +47,390+62.8% | Added |
| Cubist Systematic Strategies, LLC | 119,962 | $1.51M | 0.02% | +119,962 | New |
| Algert Global LLC | 118,104 | $1.48M | 0.03% | +118,104 | New |
| Millennium Management LLC | 116,102 | $1.46M | 0.00% | −179,504−60.7% | Reduced |
| Dark Forest Capital Management LP | 96,989 | $1.22M | 0.05% | −8,840−8.4% | Reduced |
| North Growth Management Ltd. | 97,000 | $1.22M | 0.23% | 00.0% | Unchanged |
| Bank of America Corp | 90,378 | $1.13M | 0.00% | +28,247+45.5% | Added |
| Invesco Ltd. | 89,371 | $1.12M | 0.00% | +11,165+14.3% | Added |
| Rhumbline Advisers | 86,083 | $1.08M | 0.00% | +3,345+4.0% | Added |
| Susquehanna Portfolio Strategies, LLC | 85,728 | $1.08M | 0.02% | +85,728 | New |
| Acuta Capital Partners, LLC | 83,655 | $1.05M | 1.47% | +15,196+22.2% | Added |
| Swiss National Bank | 73,100 | $917.4K | 0.00% | −7,000−8.7% | Reduced |
| Royal Bank of Canada | 72,983 | $915.0K | 0.00% | +16,212+28.6% | Added |
| Fisher Asset Management, LLC | 71,979 | $903.3K | 0.00% | +50.0% | Added |
| Qube Research & Technologies Ltd | 69,874 | $876.9K | 0.00% | +69,874 | New |
| Stifel Financial Corp | 69,730 | $875.1K | 0.00% | +2,700+4.0% | Added |
| Weiss Asset Management LP | 54,171 | $679.8K | 0.01% | +54,171 | New |
| Virginia Retirement Systems Et Al | 54,075 | $678.6K | 0.00% | +9,900+22.4% | Added |
| NEOS Investment Management LLC | 51,855 | $650.8K | 0.01% | +18,854+57.1% | Added |
| Tema ETFs LLC | 51,855 | $650.8K | 0.17% | +18,854+57.1% | Added |
| ExodusPoint Capital Management, LP | 51,669 | $648.0K | 0.01% | −81,651−61.2% | Reduced |
| Alliancebernstein L.P. | 50,030 | $627.9K | 0.00% | 00.0% | Unchanged |
| STRS Ohio | 46,300 | $581.1K | 0.00% | +46,300 | New |
| Prudential Financial Inc | 44,965 | $564.3K | 0.00% | +2,395+5.6% | Added |
| Legal & General Group Plc | 43,763 | $549.2K | 0.00% | −3,027−6.5% | Reduced |
| California State Teachers Retirement System | 42,873 | $538.1K | 0.00% | −910−2.1% | Reduced |
| O'Shaughnessy Asset Management, LLC | 41,224 | $517.4K | 0.00% | −55,105−57.2% | Reduced |
| HSBC Holdings PLC | 36,497 | $461.3K | 0.00% | +36,497 | New |
| Man Group plc | 35,406 | $444.3K | 0.00% | +24,547+226.1% | Added |
| Victory Capital Management Inc | 34,610 | $434.4K | 0.00% | −9,660−21.8% | Reduced |
| Tudor Investment Corp Et Al | 34,293 | $430.4K | 0.00% | +34,293 | New |
| Panagora Asset Management Inc | 33,559 | $421.2K | 0.00% | +33,559 | New |
| MetLife Investment Management | 33,309 | $418.0K | 0.00% | 00.0% | Unchanged |
| HRT Financial LP | 32,758 | $411.0K | 0.00% | −32,622−49.9% | Reduced |
| Commonwealth Equity Services, LLC | 32,170 | $404.0K | 0.00% | −5,472−14.5% | Reduced |
| American Century Companies Inc | 31,147 | $390.9K | 0.00% | 00.0% | Unchanged |
| XTX Topco Ltd | 31,021 | $389.3K | 0.02% | +10,816+53.5% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 29,934 | $375.7K | 0.00% | +5,403+22.0% | Added |
| Journey Strategic Wealth LLC | 29,040 | $364.5K | 0.01% | +99+0.3% | Added |
| Russell Investments Group, Ltd. | 28,312 | $355.3K | 0.00% | +25,259+827.4% | Added |
| Bank of Montreal | 27,642 | $346.9K | 0.00% | +1,730+6.7% | Added |
| Massachusetts Financial Services Co | 27,109 | $340.2K | 0.00% | +334+1.2% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 26,863 | $337.1K | 0.00% | −5,522−17.1% | Reduced |
| Price T Rowe Associates Inc | 26,816 | $337.0K | 0.00% | +2,703+11.2% | Added |
| Landscape Capital Management, L.L.C. | 26,667 | $334.7K | 0.03% | +26,667 | New |
| Creative Planning | 25,389 | $318.6K | 0.00% | +13,567+114.8% | Added |
| Ritholtz Wealth Management | 25,235 | $316.7K | 0.01% | −35,259−58.3% | Reduced |