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Zymeworks Inc.

ZYME
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001937653

No open-market purchases or sales by Zymeworks Inc. insiders were filed in the last 90 days; 202 institutions reported holding it in 13F filings for Q2 2026, worth $1.79B in total; no superinvestor holds it.

13F holders, Q1 2023

Institutional positions in Zymeworks Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
116
+21 vs. Q4 2022
Shares held
56.7M
−535.1K (−0.9%) vs. Q4 2022
Total value
$512.6M
+$62.8M (+14.0%) vs. Q4 2022
New holders
40
36 more added
Sold out
19
27 more reduced

1 institution that held it in Q4 2022 haven't filed for Q1 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ZYME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2023: 116 institutions
Q1 2021: 125 institutionsQ2 2021: 109 institutionsQ3 2021: 123 institutionsQ4 2021: 114 institutionsQ1 2022: 120 institutionsQ2 2022: 114 institutionsQ3 2022: 91 institutionsQ4 2022: 96 institutionsQ1 2023: 116 institutionsQ2 2023: 137 institutionsQ3 2023: 140 institutionsQ4 2023: 157 institutionsQ1 2024: 171 institutionsQ2 2024: 164 institutionsQ3 2024: 163 institutionsQ4 2024: 174 institutionsQ1 2025: 186 institutionsQ2 2025: 182 institutionsQ3 2025: 184 institutionsQ4 2025: 210 institutionsQ1 2026: 212 institutionsQ2 2026: 202 institutions
Value heldQ1 2023: $512.6M
Q1 2021: $1.12BQ2 2021: $1.20BQ3 2021: $1.07BQ4 2021: $693.9MQ1 2022: $327.3MQ2 2022: $253.3MQ3 2022: $293.7MQ4 2022: $449.9MQ1 2023: $512.6MQ2 2023: $547.9MQ3 2023: $395.5MQ4 2023: $674.0MQ1 2024: $713.0MQ2 2024: $580.6MQ3 2024: $834.7MQ4 2024: $973.2MQ1 2025: $840.9MQ2 2025: $949.0MQ3 2025: $1.26BQ4 2025: $1.88BQ1 2026: $1.76BQ2 2026: $1.79B
Institutions holding ZYME and their total value by quarter
QuarterHoldersValue
Q2 2026202$1.79B
Q1 2026212$1.76B
Q4 2025210$1.88B
Q3 2025184$1.26B
Q2 2025182$949.0M
Q1 2025186$840.9M
Q4 2024174$973.2M
Q3 2024163$834.7M
Q2 2024164$580.6M
Q1 2024171$713.0M
Q4 2023157$674.0M
Q3 2023140$395.5M
Q2 2023137$547.9M
Q1 2023116$512.6M
Q4 202296$449.9M
Q3 202291$293.7M
Q2 2022114$253.3M
Q1 2022120$327.3M
Q4 2021114$693.9M
Q3 2021123$1.07B
Q2 2021109$1.20B
Q1 2021125$1.12B

Institutions, Q1 2023

Shares, value and share of portfolio for each institution holding Zymeworks Inc.; share changes are against Q4 2022.

Institutions holding ZYME in Q1 2023
InstitutionSharesValue% of portfolioChange in sharesAction
EcoR1 Capital, LLC10,087,473$91.2M2.94%+2,518,900+33.3%Added
Redmile Group, LLC6,067,918$54.9M2.38%−108,000−1.7%Reduced
BVF Inc5,870,000$53.1M1.94%00.0%Unchanged
Morgan Stanley5,563,301$50.3M0.01%−10,079−0.2%Reduced
Perceptive Advisors LLC3,378,498$30.5M0.90%−1,132,777−25.1%Reduced
Rubric Capital Management LP2,854,732$25.8M1.03%−163,485−5.4%Reduced
Credit Suisse AG2,485,285$22.5M0.02%+46,190+1.9%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.2,306,472$20.9M0.07%+14,665+0.6%Added
Vanguard Group Inc2,040,149$18.4M0.00%−496,246−19.6%Reduced
Farallon Capital Management, L.L.C.2,000,000$18.1M0.11%+500,000+33.3%Added
Samsara BioCapital, LLC1,620,687$14.7M3.03%00.0%Unchanged
Tang Capital Management LLC1,100,000$9.94M1.48%+700,000+175.0%Added
BlackRock Inc.751,573$6.79M0.00%+75,166+11.1%Added
Granahan Investment Management Inc650,389$5.88M0.18%−88,059−11.9%Reduced
Millennium Management LLC649,183$5.87M0.01%+533,661+462.0%Added
Frazier Life Sciences Management, L.P.610,000$5.51M0.40%00.0%Unchanged
Deutsche Bank AG583,531$5.28M0.00%−131,909−18.4%Reduced
Timelo Investment Management Inc.479,098$4.33M5.38%+74,372+18.4%Added
Platinum Investment Management Ltd406,327$3.67M0.13%+10,407+2.6%Added
Monaco Asset Management SAM399,100$3.61M1.62%−100,900−20.2%Reduced
Susquehanna International Group, LLP386,114$3.49M0.01%+291,886+309.8%Added
Tejara Capital Ltd344,410$3.11M1.59%−61,966−15.2%Reduced
Goldman Sachs Group Inc328,078$2.97M0.00%+203,021+162.3%Added
HRT Financial LP327,026$2.96M0.04%+327,026New
Mariner, LLC321,700$2.91M0.01%−35,950−10.1%Reduced
Picton Mahoney Asset Management317,520$2.87M0.15%+58,516+22.6%Added
UBS Oconnor LLC303,732$2.75M0.07%+303,732New
Cubist Systematic Strategies, LLC295,907$2.67M0.02%+241,177+440.7%Added
Voloridge Investment Management, LLC253,204$2.29M0.01%+211,383+505.4%Added
Point72 Asset Management, L.P.198,150$1.79M0.01%−551,350−73.6%Reduced
683 Capital Management, LLC190,000$1.72M0.15%−100,000−34.5%Reduced
Royal Bank of Canada171,379$1.55M0.00%+2,962+1.8%Added
Qube Research & Technologies Ltd171,314$1.55M0.01%+171,314New
State Street Corp153,017$1.38M0.00%+51,032+50.0%Added
Victory Capital Management Inc151,950$1.37M0.00%+151,950New
Jane Street Group, LLC140,816$1.27M0.00%+140,816New
Swiss National Bank129,200$1.17M0.00%+129,200New
Caxton Associates LP120,772$1.09M0.17%+1,633+1.4%Added
North Growth Management Ltd.120,000$1.09M0.23%+45,000+60.0%Added
Bank of America Corp108,355$979.5K0.00%+80,248+285.5%Added
Jump Financial, LLC95,311$861.6K0.04%+63,424+198.9%Added
Raymond James & Associates93,235$842.8K0.00%−60,917−39.5%Reduced
Dimensional Fund Advisors LP89,793$811.7K0.00%+89,793New
Wells Fargo & Company84,867$767.2K0.00%−16,466−16.2%Reduced
Renaissance Technologies LLC83,400$754.0K0.00%−36,600−30.5%Reduced
Virginia Retirement Systems Et Al81,600$737.7K0.01%+81,600New
Squarepoint Ops LLC78,504$709.7K0.01%+78,504New
Kennedy Capital Management, Inc.78,477$709.4K0.02%+52+0.1%Added
Citigroup Inc75,451$682.1K0.00%+49,593+191.8%Added
Verition Fund Management LLC61,386$554.9K0.01%+61,386New
Corton Capital Inc.59,355$536.6K0.37%+59,355New
Raymond James Financial Services Advisors, Inc.57,827$522.8K0.00%+1,379+2.4%Added
Balyasny Asset Management LLC57,078$516.0K0.00%+57,078New
State of Wisconsin Investment Board55,215$499.1K0.00%+55,215New
Citadel Advisors LLC54,481$492.5K0.00%+53,612+6,169.4%Added
California State Teachers Retirement System52,580$475.3K0.00%+52,580New
Delphia (USA) Inc.48,104$434.9K0.53%+48,104New
Stifel Financial Corp43,825$396.2K0.00%+4,025+10.1%Added
ExodusPoint Capital Management, LP43,731$395.0K0.00%+43,731New
Two Sigma Investments, LP43,600$394.1K0.00%+5,888+15.6%Added
UBS Asset Management Americas Inc43,400$392.3K0.00%+43,400New
LMR Partners LLP43,177$390.3K0.01%+13,953+47.7%Added
Mirabella Financial Services LLP42,940$388.2K0.08%+42,940New
Connor, Clark & Lunn Investment Management Ltd.41,304$373.4K0.00%+41,304New
Allspring Global Investments Holdings, LLC39,045$353.0K0.00%+746+1.9%Added
Janus Henderson Group PLC38,894$351.4K0.00%+38,894New
Gsa Capital Partners LLP37,093$335.0K0.03%+9,230+33.1%Added
Susquehanna Fundamental Investments, LLC31,930$288.6K0.01%00.0%Unchanged
Geode Capital Management, LLC31,500$284.8K0.00%+31,500New
BlueCrest Capital Management Ltd30,987$280.1K0.03%+30,987New
Northern Trust Corp30,079$271.9K0.00%+17,247+134.4%Added
Stephens Inc29,882$270.1K0.01%−26,765−47.2%Reduced
Journey Strategic Wealth LLC28,846$260.8K0.03%00.0%Unchanged
Bank of Montreal27,649$249.9K0.00%−9,130−24.8%Reduced
Marathon Capital Management26,250$237.3K0.06%+26,250New
Commonwealth Equity Services, LLC26,044$235.0K0.00%+300+1.2%Added
Envestnet Asset Management Inc25,683$232.2K0.00%−30,482−54.3%Reduced
Diametric Capital, LP22,800$206.1K0.10%+22,800New
Lazard Asset Management LLC22,648$204.0K0.00%+5,020+28.5%Added
Fox Run Management, L.L.C.19,925$180.1K0.06%+19,925New
Legal & General Group Plc19,362$175.0K0.00%+19,362New
Tower Research Capital LLC (TRC)19,275$174.0K0.01%+15,999+488.4%Added
Teacher Retirement System of Texas18,438$167.0K0.00%+18,438New
Arizona State Retirement System17,342$156.8K0.00%+17,342New
Kapitalo Investimentos Ltda16,449$148.7K0.05%+16,449New
Wela Strategies, Inc.15,894$143.7K0.08%+15,894New
Virtus ETF Advisers LLC15,759$142.5K0.08%−6,059−27.8%Reduced
Engineers Gate Manager LP15,491$140.0K0.01%−6,829−30.6%Reduced
UBS Group AG15,066$136.2K0.00%+15,041+60,164.0%Added
Pictet Asset Management SA14,669$132.6K0.00%+14,669New
Quantbot Technologies LP13,600$122.9K0.01%+13,600New
Old Well Partners, LLC13,400$121.1K0.10%+13,400New
Man Group plc–$112.3K0.00%––
Vontobel Holding Ltd.11,999$108.5K0.00%+11,999New
Jefferies Financial Group Inc.11,563$104.5K0.00%+11,563New
Barclays PLC10,900$98.5K0.00%+10,900New
Janney Montgomery Scott LLC10,267$93.0K0.00%−48,565−82.5%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)10,203$92.2K0.00%+10,203New
Compagnie Lombard Odier SCmA10,000$90.4K0.00%00.0%Unchanged
Point72 Middle East FZE6,596$59.6K0.00%+6,596New