Zymeworks Inc.
ZYME- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001937653
No open-market purchases or sales by Zymeworks Inc. insiders were filed in the last 90 days; 202 institutions reported holding it in 13F filings for Q2 2026, worth $1.79B in total; no superinvestor holds it.
13F holders, Q4 2022
Institutional positions in Zymeworks Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 96
- +6 vs. Q3 2022
- Shares held
- 57.2M
- +9.76M (+20.6%) vs. Q3 2022
- Total value
- $449.9M
- +$157.9M (+54.1%) vs. Q3 2022
- New holders
- 33
- 31 more added
- Sold out
- 27
- 17 more reduced
1 institution that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ZYME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 202 | $1.79B |
| Q1 2026 | 212 | $1.76B |
| Q4 2025 | 210 | $1.88B |
| Q3 2025 | 184 | $1.26B |
| Q2 2025 | 182 | $949.0M |
| Q1 2025 | 186 | $840.9M |
| Q4 2024 | 174 | $973.2M |
| Q3 2024 | 163 | $834.7M |
| Q2 2024 | 164 | $580.6M |
| Q1 2024 | 171 | $713.0M |
| Q4 2023 | 157 | $674.0M |
| Q3 2023 | 140 | $395.5M |
| Q2 2023 | 137 | $547.9M |
| Q1 2023 | 116 | $512.6M |
| Q4 2022 | 96 | $449.9M |
| Q3 2022 | 91 | $293.7M |
| Q2 2022 | 114 | $253.3M |
| Q1 2022 | 120 | $327.3M |
| Q4 2021 | 114 | $693.9M |
| Q3 2021 | 123 | $1.07B |
| Q2 2021 | 109 | $1.20B |
| Q1 2021 | 125 | $1.12B |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Zymeworks Inc.; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| EcoR1 Capital, LLC | 7,568,573 | $59.5M | 1.81% | +7,568,573 | New |
| Redmile Group, LLC | 6,175,918 | $48.5M | 1.99% | +410,100+7.1% | Added |
| BVF Inc | 5,870,000 | $46.1M | 1.95% | +5,870,000 | New |
| Morgan Stanley | 5,573,380 | $43.8M | 0.00% | +314,405+6.0% | Added |
| Perceptive Advisors LLC | 4,511,275 | $35.5M | 1.02% | +111,176+2.5% | Added |
| Rubric Capital Management LP | 3,018,217 | $23.7M | 1.04% | +3,018,217 | New |
| Vanguard Group Inc | 2,536,395 | $19.9M | 0.00% | +2,012,412+384.1% | Added |
| Credit Suisse AG | 2,439,095 | $19.2M | 0.02% | −1,277−0.1% | Reduced |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 2,291,807 | $18.0M | 0.06% | +782,770+51.9% | Added |
| Baker Bros. Advisors LP | 1,708,472 | $13.4M | 0.08% | 00.0% | Unchanged |
| Samsara BioCapital, LLC | 1,620,687 | $12.7M | 2.74% | +649,700+66.9% | Added |
| Farallon Capital Management, L.L.C. | 1,500,000 | $11.8M | 0.08% | +1,500,000 | New |
| Point72 Asset Management, L.P. | 749,500 | $5.89M | 0.02% | +505,500+207.2% | Added |
| Brookfield Asset Management Inc. | 741,186 | $5.83M | 0.02% | +537,534+263.9% | Added |
| Sessa Capital IM, L.P. | 740,878 | $5.82M | 0.36% | +740,878 | New |
| Granahan Investment Management Inc | 738,448 | $5.80M | 0.18% | +150,640+25.6% | Added |
| Deutsche Bank AG | 715,440 | $5.62M | 0.00% | +623,781+680.5% | Added |
| BlackRock Inc. | 676,407 | $5.32M | 0.00% | +94,698+16.3% | Added |
| Frazier Life Sciences Management, L.P. | 610,000 | $4.79M | 0.30% | +610,000 | New |
| Woodline Partners LP | 600,403 | $4.72M | 0.07% | −953,679−61.4% | Reduced |
| Monaco Asset Management SAM | 500,000 | $3.93M | 1.40% | +500,000 | New |
| Artal Group S.A. | 450,000 | $3.54M | 0.20% | 00.0% | Unchanged |
| Tejara Capital Ltd | 406,376 | $3.19M | 1.86% | +406,376 | New |
| Timelo Investment Management Inc. | 404,726 | $3.18M | 3.13% | +500+0.1% | Added |
| Tang Capital Management LLC | 400,000 | $3.14M | 0.46% | +400,000 | New |
| Platinum Investment Management Ltd | 395,920 | $3.11M | 0.12% | +21,928+5.9% | Added |
| D. E. Shaw & Co., Inc. | 369,187 | $2.90M | 0.00% | +280,710+317.3% | Added |
| Mariner, LLC | 357,650 | $2.81M | 0.01% | +357,650 | New |
| 683 Capital Management, LLC | 290,000 | $2.28M | 0.21% | +290,000 | New |
| Picton Mahoney Asset Management | 259,004 | $2.04M | 0.11% | +154,599+148.1% | Added |
| Sectoral Asset Management Inc | 192,124 | $1.51M | 0.29% | +192,124 | New |
| Royal Bank of Canada | 168,417 | $1.32M | 0.00% | +134,535+397.1% | Added |
| Raymond James & Associates | 154,152 | $1.21M | 0.00% | −11,781−7.1% | Reduced |
| Ci Investments Inc. | 147,170 | $1.16M | 0.01% | +700+0.5% | Added |
| Goldman Sachs Group Inc | 125,057 | $982.9K | 0.00% | +125,057 | New |
| Candriam Luxembourg S.C.A. | 120,305 | $945.6K | 0.01% | +120,305 | New |
| Renaissance Technologies LLC | 120,000 | $943.0K | 0.00% | +62,223+107.7% | Added |
| Caxton Associates LP | 119,139 | $936.4K | 0.07% | +119,139 | New |
| Thrivent Financial for Lutherans | 117,092 | $919.0K | 0.00% | +101,010+628.1% | Added |
| Millennium Management LLC | 115,522 | $908.0K | 0.00% | −77,106−40.0% | Reduced |
| State Street Corp | 101,985 | $801.6K | 0.00% | +2,622+2.6% | Added |
| Wells Fargo & Company | 101,333 | $796.5K | 0.00% | −7,593−7.0% | Reduced |
| Susquehanna International Group, LLP | 94,228 | $740.6K | 0.00% | −87,519−48.2% | Reduced |
| Advisor Group Holdings, Inc. | 85,083 | $669.0K | 0.00% | +84,983+84,983.0% | Added |
| Kennedy Capital Management, Inc. | 78,425 | $616.4K | 0.02% | +310.0% | Added |
| North Growth Management Ltd. | 75,000 | $591.0K | 0.13% | 00.0% | Unchanged |
| Janney Montgomery Scott LLC | 58,832 | $462.0K | 0.00% | +6,456+12.3% | Added |
| Stephens Inc | 56,647 | $445.2K | 0.01% | +56,647 | New |
| Raymond James Financial Services Advisors, Inc. | 56,448 | $443.7K | 0.00% | −16,076−22.2% | Reduced |
| Envestnet Asset Management Inc | 56,165 | $441.5K | 0.00% | +56,165 | New |
| Cubist Systematic Strategies, LLC | 54,730 | $430.2K | 0.00% | +46,206+542.1% | Added |
| AlphaCentric Advisors LLC | 52,500 | $412.6K | 0.41% | +52,500 | New |
| Invesco Ltd. | 51,180 | $402.3K | 0.00% | −258−0.5% | Reduced |
| Simplex Trading, LLC | 48,192 | $378.0K | 0.02% | +13,122+37.4% | Added |
| Voloridge Investment Management, LLC | 41,821 | $328.7K | 0.00% | −248,789−85.6% | Reduced |
| Stifel Financial Corp | 39,800 | $312.8K | 0.00% | +39,800 | New |
| Allspring Global Investments Holdings, LLC | 38,299 | $301.0K | 0.00% | −5,628−12.8% | Reduced |
| Two Sigma Investments, LP | 37,712 | $296.4K | 0.00% | +37,712 | New |
| Bank of Montreal | 36,779 | $289.1K | 0.00% | −10,341−21.9% | Reduced |
| Susquehanna Fundamental Investments, LLC | 31,930 | $251.0K | 0.00% | +31,930 | New |
| Jump Financial, LLC | 31,887 | $250.6K | 0.01% | +31,887 | New |
| Parallax Volatility Advisers, L.P. | 30,000 | $235.8K | 0.01% | 00.0% | Unchanged |
| LMR Partners LLP | 29,224 | $229.7K | 0.01% | +29,224 | New |
| Journey Strategic Wealth LLC | 28,846 | $226.7K | 0.03% | 00.0% | Unchanged |
| Bank of America Corp | 28,107 | $220.9K | 0.00% | +25,321+908.9% | Added |
| Group One Trading, L.P. | 27,939 | $219.6K | 0.01% | −14,613−34.3% | Reduced |
| Gsa Capital Partners LLP | 27,863 | $219.0K | 0.03% | +27,863 | New |
| Citigroup Inc | 25,858 | $203.2K | 0.00% | +25,810+53,770.8% | Added |
| Commonwealth Equity Services, LLC | 25,744 | $202.0K | 0.00% | 00.0% | Unchanged |
| Walleye Trading LLC | 24,378 | $191.6K | 0.00% | +8,864+57.1% | Added |
| Engineers Gate Manager LP | 22,320 | $175.4K | 0.01% | +22,320 | New |
| Virtus ETF Advisers LLC | 21,818 | $171.5K | 0.09% | +3,838+21.3% | Added |
| Man Group plc | 18,289 | $143.8K | 0.00% | −142,256−88.6% | Reduced |
| Lazard Asset Management LLC | 17,628 | $138.0K | 0.00% | 00.0% | Unchanged |
| Forefront Wealth Management Inc. | 13,400 | $127.8K | 0.17% | +13,400 | New |
| Russell Investments Group, Ltd. | 14,144 | $111.2K | 0.00% | −39,611−73.7% | Reduced |
| Alpine Global Management, LLC | 13,046 | $103.0K | 0.03% | +13,046 | New |
| Northern Trust Corp | 12,832 | $100.9K | 0.00% | −1,403−9.9% | Reduced |
| Compagnie Lombard Odier SCmA | 10,000 | $79.0K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 3,276 | $26.0K | 0.00% | +3,276 | New |
| Cutler Group LP | 3,000 | $23.0K | 0.00% | +200+7.1% | Added |
| Advisory Services Network, LLC | 1,650 | $13.0K | 0.00% | +1,650 | New |
| Rockefeller Capital Management L.P. | 1,500 | $11.0K | 0.00% | 00.0% | Unchanged |
| IFP Advisors, Inc | 600 | $8.00K | 0.00% | +300+100.0% | Added |
| Citadel Advisors LLC | 869 | $6.83K | 0.00% | −122,458−99.3% | Reduced |
| Stonehage Fleming Financial Services Holdings Ltd | 550 | $4.32K | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 350 | $2.75K | 0.00% | +350 | New |
| HighMark Wealth Management LLC | 280 | $2.20K | 0.00% | 00.0% | Unchanged |
| Steward Partners Investment Advisory, LLC | 158 | $1.24K | 0.00% | 00.0% | Unchanged |
| TD Waterhouse Canada Inc. | 96 | $987 | 0.00% | −375−79.6% | Reduced |
| Eagle Bay Advisors LLC | 110 | $865 | 0.00% | 00.0% | Unchanged |
| GWM Advisors LLC | 100 | $786 | 0.00% | +100 | New |
| UBS Group AG | 25 | $197 | 0.00% | 00.0% | Unchanged |
| CoreCap Advisors, LLC | 18 | $141 | 0.00% | +18 | New |
| JPMorgan Chase & Co | 11 | $0 | 0.00% | 00.0% | Unchanged |
| Asset Dedication, LLC | 47 | $0 | 0.00% | +47 | New |
| Armistice Capital, LLC | 0 | $0 | 0.00% | −5,785,000−100.0% | Sold out |
| Eventide Asset Management, LLC | 0 | $0 | 0.00% | −5,380,200−100.0% | Sold out |
| Camber Capital Management LP | 0 | $0 | 0.00% | −2,865,000−100.0% | Sold out |
| Alyeska Investment Group, L.P. | 0 | $0 | 0.00% | −1,502,720−100.0% | Sold out |