Zymeworks Inc.
ZYME- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001937653
No open-market purchases or sales by Zymeworks Inc. insiders were filed in the last 90 days; 202 institutions reported holding it in 13F filings for Q2 2026, worth $1.79B in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Zymeworks Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 186
- +15 vs. Q4 2024
- Shares held
- 70.6M
- +5.43M (+8.3%) vs. Q4 2024
- Total value
- $840.9M
- −$113.0M (−11.8%) vs. Q4 2024
- New holders
- 32
- 60 more added
- Sold out
- 17
- 64 more reduced
3 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ZYME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 202 | $1.79B |
| Q1 2026 | 212 | $1.76B |
| Q4 2025 | 210 | $1.88B |
| Q3 2025 | 184 | $1.26B |
| Q2 2025 | 182 | $949.0M |
| Q1 2025 | 186 | $840.9M |
| Q4 2024 | 174 | $973.2M |
| Q3 2024 | 163 | $834.7M |
| Q2 2024 | 164 | $580.6M |
| Q1 2024 | 171 | $713.0M |
| Q4 2023 | 157 | $674.0M |
| Q3 2023 | 140 | $395.5M |
| Q2 2023 | 137 | $547.9M |
| Q1 2023 | 116 | $512.6M |
| Q4 2022 | 96 | $449.9M |
| Q3 2022 | 91 | $293.7M |
| Q2 2022 | 114 | $253.3M |
| Q1 2022 | 120 | $327.3M |
| Q4 2021 | 114 | $693.9M |
| Q3 2021 | 123 | $1.07B |
| Q2 2021 | 109 | $1.20B |
| Q1 2021 | 125 | $1.12B |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Zymeworks Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| EcoR1 Capital, LLC | 17,259,548 | $205.6M | 12.23% | +2,231,469+14.8% | Added |
| Redmile Group, LLC | 4,788,945 | $57.0M | 5.39% | −51,518−1.1% | Reduced |
| Rubric Capital Management LP | 4,338,444 | $51.7M | 0.93% | +421,113+10.7% | Added |
| BVF Inc | 4,308,935 | $51.3M | 2.09% | 00.0% | Unchanged |
| BlackRock, Inc. | 4,089,421 | $48.7M | 0.00% | −95,535−2.3% | Reduced |
| Morgan Stanley | 4,073,463 | $48.5M | 0.00% | −127,974−3.0% | Reduced |
| UBS Asset Management Americas Inc | 3,879,945 | $46.2M | 0.01% | +2,514,834+184.2% | Added |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 2,197,879 | $26.2M | 0.07% | +60,226+2.8% | Added |
| Perceptive Advisors LLC | 1,864,672 | $22.2M | 0.79% | −265,348−12.5% | Reduced |
| Vanguard Group Inc | 1,767,041 | $21.0M | 0.00% | −726,247−29.1% | Reduced |
| Deutsche Bank AG | 1,552,612 | $18.5M | 0.01% | +5,840+0.4% | Added |
| Blackstone Group Inc. | 1,382,587 | $16.5M | 0.07% | +812,872+142.7% | Added |
| Nextech Invest, Ltd. | 1,113,946 | $13.3M | 3.08% | +1,113,946 | New |
| Tang Capital Management LLC | 1,100,000 | $13.1M | 0.72% | 00.0% | Unchanged |
| State Street Corp | 1,085,133 | $12.9M | 0.00% | +1720.0% | Added |
| Dimensional Fund Advisors LP | 1,079,458 | $12.9M | 0.00% | +106,716+11.0% | Added |
| Prosight Management, LP | 957,229 | $11.4M | 3.75% | +137,229+16.7% | Added |
| Bridgeway Capital Management, LLC | 766,944 | $9.13M | 0.23% | +7,291+1.0% | Added |
| Geode Capital Management, LLC | 705,035 | $8.40M | 0.00% | +15,151+2.2% | Added |
| Samsara BioCapital, LLC | 666,667 | $7.94M | 1.42% | −333,333−33.3% | Reduced |
| Vestal Point Capital, LP | 500,000 | $5.96M | 0.43% | +315,000+170.3% | Added |
| Assenagon Asset Management S.A. | 495,067 | $5.90M | 0.01% | −147,184−22.9% | Reduced |
| Renaissance Technologies LLC | 450,600 | $5.37M | 0.01% | +164,900+57.7% | Added |
| Granahan Investment Management Inc | 407,589 | $4.85M | 0.24% | −3,531−0.9% | Reduced |
| Farallon Capital Management, L.L.C. | 400,000 | $4.76M | 0.03% | −929,974−69.9% | Reduced |
| Northern Trust Corp | 386,923 | $4.61M | 0.00% | −7,907−2.0% | Reduced |
| Jupiter Asset Management Ltd | 369,499 | $4.40M | 0.04% | 00.0% | Unchanged |
| Empowered Funds, LLC | 360,044 | $4.29M | 0.06% | +7,291+2.1% | Added |
| Susquehanna International Group, LLP | 351,161 | $4.18M | 0.01% | +299,645+581.7% | Added |
| Schroder Investment Management Group | 321,949 | $3.98M | 0.00% | −15,212−4.5% | Reduced |
| Millennium Management LLC | 295,606 | $3.52M | 0.00% | +295,606 | New |
| Silvercrest Asset Management Group LLC | 280,726 | $3.34M | 0.02% | −1,619−0.6% | Reduced |
| Platinum Investment Management Ltd | 278,658 | $3.32M | 0.19% | −27,802−9.1% | Reduced |
| Walleye Capital LLC | 247,959 | $2.95M | 0.03% | −204,845−45.2% | Reduced |
| Hillsdale Investment Management Inc. | 236,925 | $2.82M | 0.14% | +6,900+3.0% | Added |
| Trexquant Investment LP | 220,809 | $2.63M | 0.03% | +118,813+116.5% | Added |
| UBS Group AG | 214,300 | $2.55M | 0.00% | +47,404+28.4% | Added |
| Picton Mahoney Asset Management | 208,029 | $2.48M | 0.08% | +1,460+0.7% | Added |
| Norges Bank | 201,700 | $2.40M | 0.00% | 00.0% | Unchanged |
| Goldman Sachs Group Inc | 200,047 | $2.38M | 0.00% | −49,913−20.0% | Reduced |
| Nuveen, LLC | 198,812 | $2.37M | 0.00% | +198,812 | New |
| Tejara Capital Ltd | 189,409 | $2.26M | 1.11% | +150,872+391.5% | Added |
| Wellington Management Group LLP | 182,246 | $2.17M | 0.00% | −36,852−16.8% | Reduced |
| Federated Hermes, Inc. | 181,912 | $2.17M | 0.00% | +286+0.2% | Added |
| Citadel Advisors LLC | 180,670 | $2.15M | 0.00% | +122,312+209.6% | Added |
| Opaleye Management Inc. | 175,000 | $2.08M | 0.46% | +175,000 | New |
| Kennedy Capital Management, Inc. | 136,319 | $1.62M | 0.04% | −3,634−2.6% | Reduced |
| Jane Street Group, LLC | 135,763 | $1.62M | 0.00% | +112,636+487.0% | Added |
| Charles Schwab Investment Management Inc | 133,639 | $1.59M | 0.00% | +2,333+1.8% | Added |
| ExodusPoint Capital Management, LP | 133,320 | $1.59M | 0.02% | +133,320 | New |
| Bank of New York Mellon Corp | 120,727 | $1.44M | 0.00% | +440.0% | Added |
| Raymond James Financial Inc | 116,711 | $1.39M | 0.00% | +56,069+92.5% | Added |
| Verition Fund Management LLC | 114,156 | $1.36M | 0.01% | +98,342+621.9% | Added |
| Dark Forest Capital Management LP | 105,829 | $1.26M | 0.06% | +105,829 | New |
| Wells Fargo & Company | 100,309 | $1.19M | 0.00% | −63,749−38.9% | Reduced |
| SG Americas Securities, LLC | 98,165 | $1.17M | 0.00% | +71,383+266.5% | Added |
| North Growth Management Ltd. | 97,000 | $1.15M | 0.24% | 00.0% | Unchanged |
| O'Shaughnessy Asset Management, LLC | 96,329 | $1.15M | 0.01% | −36,248−27.3% | Reduced |
| Voloridge Investment Management, LLC | 95,394 | $1.14M | 0.00% | +51,686+118.3% | Added |
| Aquilo Capital Management, LLC | 84,482 | $1.01M | 2.71% | +84,482 | New |
| Rhumbline Advisers | 82,738 | $985.4K | 0.00% | −21,138−20.3% | Reduced |
| Swiss National Bank | 80,100 | $954.0K | 0.00% | −10,100−11.2% | Reduced |
| Invesco Ltd. | 78,206 | $931.4K | 0.00% | +8,824+12.7% | Added |
| Barclays PLC | 75,430 | $898.4K | 0.00% | −145,460−65.9% | Reduced |
| Credit Agricole S A | 75,000 | $893.3K | 0.00% | 00.0% | Unchanged |
| Fisher Asset Management, LLC | 71,974 | $857.2K | 0.00% | +8,374+13.2% | Added |
| Acuta Capital Partners, LLC | 68,459 | $815.3K | 0.95% | +1,219+1.8% | Added |
| Stifel Financial Corp | 67,030 | $798.3K | 0.00% | +2,700+4.2% | Added |
| HRT Financial LP | 65,380 | $778.0K | 0.00% | −30,594−31.9% | Reduced |
| Squarepoint Ops LLC | 63,602 | $757.5K | 0.00% | +63,602 | New |
| D. E. Shaw & Co., Inc. | 63,099 | $751.5K | 0.00% | +42,259+202.8% | Added |
| Bank of America Corp | 62,131 | $740.0K | 0.00% | +30,431+96.0% | Added |
| Ritholtz Wealth Management | 60,494 | $720.5K | 0.02% | −13,972−18.8% | Reduced |
| Royal Bank of Canada | 56,771 | $676.0K | 0.00% | −4,155−6.8% | Reduced |
| Alliancebernstein L.P. | 50,030 | $595.9K | 0.00% | 00.0% | Unchanged |
| ADAR1 Capital Management, LLC | 50,000 | $595.5K | 0.11% | +50,000 | New |
| Envestnet Asset Management Inc | 49,512 | $589.7K | 0.00% | −4,578−8.5% | Reduced |
| AQR Capital Management LLC | 48,485 | $577.5K | 0.00% | +22,411+86.0% | Added |
| Legal & General Group Plc | 46,790 | $557.3K | 0.00% | −292−0.6% | Reduced |
| Victory Capital Management Inc | 44,270 | $527.3K | 0.00% | −7,310−14.2% | Reduced |
| Virginia Retirement Systems Et Al | 44,175 | $526.1K | 0.00% | +44,175 | New |
| California State Teachers Retirement System | 43,783 | $521.5K | 0.00% | 00.0% | Unchanged |
| Prudential Financial Inc | 42,570 | $507.0K | 0.00% | +22,910+116.5% | Added |
| HighVista Strategies LLC | 41,607 | $495.5K | 0.19% | +41,607 | New |
| Citigroup Inc | 41,198 | $490.7K | 0.00% | −41,938−50.4% | Reduced |
| Intech Investment Management LLC | 40,263 | $479.5K | 0.00% | +6,405+18.9% | Added |
| JPMorgan Chase & Co | 38,409 | $457.5K | 0.00% | −73,574−65.7% | Reduced |
| State of Wisconsin Investment Board | 37,824 | $450.5K | 0.00% | −27,557−42.1% | Reduced |
| Commonwealth Equity Services, LLC | 37,642 | $448.0K | 0.00% | +6,682+21.6% | Added |
| MetLife Investment Management | 33,309 | $396.7K | 0.00% | −637−1.9% | Reduced |
| NEOS Investment Management LLC | 33,001 | $393.0K | 0.01% | +33,001 | New |
| Tema ETFs LLC | 33,001 | $393.0K | 0.12% | +33,001 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 32,385 | $385.7K | 0.00% | +1,427+4.6% | Added |
| Franklin Resources Inc | 32,160 | $383.0K | 0.00% | +32,160 | New |
| Quest Partners LLC | 31,676 | $377.3K | 0.04% | +28,868+1,028.1% | Added |
| American Century Companies Inc | 31,147 | $371.0K | 0.00% | −8,795−22.0% | Reduced |
| Journey Strategic Wealth LLC | 28,941 | $344.7K | 0.01% | +44+0.2% | Added |
| Massachusetts Financial Services Co | 26,775 | $318.9K | 0.00% | −610−2.2% | Reduced |
| Corebridge Financial, Inc. | 26,719 | $318.2K | 0.00% | −396−1.5% | Reduced |
| Bank of Montreal | 25,912 | $308.6K | 0.00% | −36−0.1% | Reduced |