Zymeworks Inc.
ZYME- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001937653
No open-market purchases or sales by Zymeworks Inc. insiders were filed in the last 90 days; 202 institutions reported holding it in 13F filings for Q2 2026, worth $1.82B in total; no superinvestor holds it.
13F holders, Q2 2026
Institutional positions in Zymeworks Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 202
- −6 vs. Q1 2026
- Shares held
- 69.6M
- −625.2K (−0.9%) vs. Q1 2026
- Total value
- $1.82B
- +$59.8M (+3.4%) vs. Q1 2026
- New holders
- 24
- 61 more added
- Sold out
- 30
- 73 more reduced
4 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ZYME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 202 | $1.82B |
| Q1 2026 | 212 | $1.76B |
| Q4 2025 | 210 | $1.88B |
| Q3 2025 | 184 | $1.26B |
| Q2 2025 | 182 | $949.9M |
| Q1 2025 | 186 | $841.1M |
| Q4 2024 | 174 | $973.2M |
| Q3 2024 | 163 | $835.2M |
| Q2 2024 | 164 | $581.0M |
| Q1 2024 | 171 | $824.0M |
| Q4 2023 | 157 | $725.2M |
| Q3 2023 | 140 | $395.6M |
| Q2 2023 | 137 | $548.0M |
| Q1 2023 | 116 | $512.8M |
| Q4 2022 | 96 | $449.9M |
| Q3 2022 | 91 | $293.7M |
| Q2 2022 | 114 | $253.3M |
| Q1 2022 | 120 | $327.3M |
| Q4 2021 | 114 | $756.7M |
| Q3 2021 | 123 | $1.07B |
| Q2 2021 | 109 | $1.35B |
| Q1 2021 | 125 | $1.12B |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Zymeworks Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| EcoR1 Capital, LLC | 22,970,388 | $600.4M | 29.77% | 00.0% | Unchanged |
| Rubric Capital Management LP | 7,000,000 | $183.0M | 1.68% | 00.0% | Unchanged |
| BlackRock, Inc. | 4,251,030 | $111.1M | 0.00% | −302,858−6.7% | Reduced |
| Perceptive Advisors LLC | 4,182,953 | $109.3M | 1.70% | +672,875+19.2% | Added |
| BVF Inc | 3,649,142 | $95.4M | 2.44% | −85,000−2.3% | Reduced |
| Assenagon Asset Management S.A. | 2,504,054 | $65.5M | 0.04% | +1,776,068+244.0% | Added |
| Morgan Stanley | 2,231,260 | $58.3M | 0.00% | −249,308−10.1% | Reduced |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1,781,116 | $46.6M | 0.05% | −126,923−6.7% | Reduced |
| Vanguard Capital Management LLC | 1,558,998 | $40.8M | 0.00% | −146,582−8.6% | Reduced |
| Nextech Invest, Ltd. | 1,113,946 | $29.1M | 1.38% | 00.0% | Unchanged |
| State Street Corp | 1,088,216 | $28.4M | 0.00% | +76,439+7.6% | Added |
| Dimensional Fund Advisors LP | 994,955 | $26.0M | 0.00% | −144,180−12.7% | Reduced |
| Citadel Advisors LLC | 914,136 | $23.9M | 0.01% | −235,882−20.5% | Reduced |
| Nomura Asset Management International Inc. | 889,802 | $23.3M | 0.03% | +889,802 | New |
| FMR LLC | 702,568 | $18.4M | 0.00% | +35,415+5.3% | Added |
| Geode Capital Management, LLC | 692,410 | $18.1M | 0.00% | +32,470+4.9% | Added |
| Prosight Management, LP | 674,434 | $17.6M | 3.04% | +135,385+25.1% | Added |
| Qube Research & Technologies Ltd | 593,590 | $15.5M | 0.02% | +81,653+15.9% | Added |
| Vanguard Portfolio Management LLC | 510,032 | $13.3M | 0.00% | +10,157+2.0% | Added |
| Redmile Group, LLC | 491,654 | $12.9M | 0.86% | 00.0% | Unchanged |
| Capricorn Fund Managers Ltd | 486,529 | $12.7M | 1.02% | −520,681−51.7% | Reduced |
| Goldman Sachs Group Inc | 470,822 | $12.3M | 0.00% | −128,664−21.5% | Reduced |
| Arrowstreet Capital, Limited Partnership | 418,497 | $10.9M | 0.00% | −325,401−43.7% | Reduced |
| Deutsche Bank AG | 397,190 | $10.4M | 0.00% | −524,060−56.9% | Reduced |
| Hillsdale Investment Management Inc. | 382,922 | $10.0M | 0.23% | +37,300+10.8% | Added |
| First Trust Advisors LP | 340,363 | $8.90M | 0.01% | +340,363 | New |
| Granahan Investment Management Inc | 336,157 | $8.79M | 0.31% | +85,384+34.0% | Added |
| Northern Trust Corp | 321,073 | $8.39M | 0.00% | +863+0.3% | Added |
| Pictet Asset Management Holding SA | 308,187 | $7.45M | 0.01% | +298,931+3,229.6% | Added |
| Picton Mahoney Asset Management | 271,343 | $7.09M | 0.07% | +14,653+5.7% | Added |
| Silvercrest Asset Management Group LLC | 223,766 | $5.85M | 0.04% | +60,117+36.7% | Added |
| Bank of America Corp | 219,071 | $5.73M | 0.00% | −17,683−7.5% | Reduced |
| Wells Fargo & Company | 217,199 | $5.68M | 0.00% | +27,563+14.5% | Added |
| SummitTX Capital, L.P. | 210,802 | $5.51M | 0.15% | −110,625−34.4% | Reduced |
| Man Group plc | 210,779 | $5.51M | 0.01% | +20,889+11.0% | Added |
| Federated Hermes, Inc. | 187,995 | $4.91M | 0.01% | +5,585+3.1% | Added |
| Raymond James Financial Inc | 166,416 | $4.35M | 0.00% | −9,995−5.7% | Reduced |
| State of Wisconsin Investment Board | 155,579 | $4.07M | 0.01% | +89,473+135.3% | Added |
| Charles Schwab Investment Management Inc | 152,416 | $3.98M | 0.00% | −32,708−17.7% | Reduced |
| Kennedy Capital Management, Inc. | 145,386 | $3.80M | 0.07% | −2,840−1.9% | Reduced |
| D. E. Shaw & Co., Inc. | 144,807 | $3.79M | 0.00% | −90,814−38.5% | Reduced |
| Diadema Partners LP | 142,132 | $3.72M | 1.31% | 00.0% | Unchanged |
| Citigroup Inc | 131,441 | $3.44M | 0.00% | +17,114+15.0% | Added |
| Bank of New York Mellon Corp | 131,106 | $3.43M | 0.00% | +7,001+5.6% | Added |
| XTX Topco Ltd | 125,877 | $3.29M | 0.04% | −18,005−12.5% | Reduced |
| Nuveen, LLC | 119,389 | $3.12M | 0.00% | −532,273−81.7% | Reduced |
| Panagora Asset Management Inc | 118,603 | $3.10M | 0.01% | −88,251−42.7% | Reduced |
| UBS Group AG | 115,095 | $3.01M | 0.00% | −56,684−33.0% | Reduced |
| Invesco Ltd. | 112,212 | $2.93M | 0.00% | −13,418−10.7% | Reduced |
| AQR Capital Management LLC | 111,282 | $2.91M | 0.00% | +20,613+22.7% | Added |
| Wellington Management Group LLP | 110,014 | $2.88M | 0.00% | −28,676−20.7% | Reduced |
| Toroso Investments, LLC | 105,615 | $2.76M | 0.01% | +684+0.7% | Added |
| Tema ETFs LLC | 105,615 | $2.76M | 0.09% | +684+0.7% | Added |
| Platinum Investment Management Ltd | 105,184 | $2.75M | 0.68% | 00.0% | Unchanged |
| Manatuck Hill Partners, LLC | 100,000 | $2.61M | 0.87% | +60,000+150.0% | Added |
| JPMorgan Chase & Co | 106,398 | $2.56M | 0.00% | −7,674−6.7% | Reduced |
| Kornitzer Capital Management Inc | 88,800 | $2.32M | 0.05% | 00.0% | Unchanged |
| Mackenzie Financial Corp | 87,745 | $2.29M | 0.00% | +5,019+6.1% | Added |
| Principal Financial Group Inc | 84,990 | $2.22M | 0.00% | +6,443+8.2% | Added |
| Y-Intercept (Hong Kong) Ltd | 83,455 | $2.18M | 0.04% | +83,455 | New |
| LMR Partners LLP | 82,500 | $2.16M | 0.02% | +82,500 | New |
| Ameriprise Financial Inc | 82,264 | $2.15M | 0.00% | +8,042+10.8% | Added |
| UBS Asset Management Americas Inc | 81,359 | $2.13M | 0.00% | −238,026−74.5% | Reduced |
| Vanguard Fiduciary Trust Co | 80,120 | $2.09M | 0.00% | −4,283−5.1% | Reduced |
| Stifel Financial Corp | 77,214 | $2.02M | 0.00% | +458+0.6% | Added |
| Franklin Resources Inc | 76,528 | $2.00M | 0.00% | −1,131−1.5% | Reduced |
| Rhumbline Advisers | 75,066 | $1.96M | 0.00% | −333−0.4% | Reduced |
| Swiss National Bank | 74,200 | $1.94M | 0.00% | 00.0% | Unchanged |
| Martingale Asset Management L P | 73,282 | $1.92M | 0.05% | +40,518+123.7% | Added |
| Two Sigma Investments, LP | 71,874 | $1.88M | 0.00% | +71,874 | New |
| Dana Investment Advisors, Inc. | 71,660 | $1.87M | 0.05% | +15,553+27.7% | Added |
| Credit Agricole S A | 71,000 | $1.86M | 0.00% | −4,000−5.3% | Reduced |
| Fisher Asset Management, LLC | 70,775 | $1.85M | 0.00% | −30,664−30.2% | Reduced |
| Segall Bryant & Hamill, LLC | 66,836 | $1.75M | 0.02% | +21,110+46.2% | Added |
| Verdad Advisers, LP | 66,688 | $1.74M | 1.67% | −16,010−19.4% | Reduced |
| Susquehanna Portfolio Strategies, LLC | 65,248 | $1.71M | 0.03% | −34,547−34.6% | Reduced |
| Campbell & CO Investment Adviser LLC | 60,874 | $1.59M | 0.08% | +5,991+10.9% | Added |
| Royal Bank of Canada | 56,278 | $1.47M | 0.00% | +8,918+18.8% | Added |
| Alliancebernstein L.P. | 55,896 | $1.40M | 0.00% | 00.0% | Unchanged |
| Virtus Investment Advisers, Inc. | 50,825 | $1.33M | 0.31% | +40,123+374.9% | Added |
| Envestnet Asset Management Inc | 48,675 | $1.27M | 0.00% | +8,256+20.4% | Added |
| Russell Investments Group, Ltd. | 47,867 | $1.25M | 0.00% | +417+0.9% | Added |
| Quantinno Capital Management LP | 47,642 | $1.25M | 0.00% | +8,002+20.2% | Added |
| North Growth Management Ltd. | 46,000 | $1.20M | 0.15% | 00.0% | Unchanged |
| Legal & General Group Plc | 43,160 | $1.13M | 0.00% | +16,951+64.7% | Added |
| Victory Capital Management Inc | 42,524 | $1.11M | 0.00% | +120+0.3% | Added |
| Marshall Wace, LLP | 40,948 | $1.07M | 0.00% | +8,725+27.1% | Added |
| O'Shaughnessy Asset Management, LLC | 39,534 | $1.03M | 0.00% | +2,405+6.5% | Added |
| Price T Rowe Associates Inc | 38,486 | $1.01M | 0.00% | +2,999+8.5% | Added |
| California State Teachers Retirement System | 37,744 | $986.6K | 0.00% | +355+0.9% | Added |
| Jacobs Levy Equity Management, Inc | 36,922 | $965.1K | 0.00% | −5,864−13.7% | Reduced |
| Tudor Investment Corp Et Al | 36,471 | $953.4K | 0.00% | −404−1.1% | Reduced |
| HighTower Advisors, LLC | 36,100 | $943.7K | 0.00% | −162−0.4% | Reduced |
| Persistent Asset Partners Ltd | 35,935 | $939.3K | 0.30% | 00.0% | Unchanged |
| HighVista Strategies LLC | 34,013 | $889.1K | 0.20% | −72−0.2% | Reduced |
| Commonwealth Equity Services, LLC | 32,052 | $837.8K | 0.00% | +6,021+23.1% | Added |
| Manufacturers Life Insurance Company, The | 30,886 | $807.4K | 0.00% | −706−2.2% | Reduced |
| Creative Planning | 29,731 | $777.2K | 0.00% | −2,663−8.2% | Reduced |
| SBI Okasan Asset Management Co.Ltd. | 32,000 | $771.2K | 0.03% | 00.0% | Unchanged |
| MetLife Investment Management | 27,884 | $728.9K | 0.00% | −1,769−6.0% | Reduced |