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Zymeworks Inc.

ZYME
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001937653

No open-market purchases or sales by Zymeworks Inc. insiders were filed in the last 90 days; 202 institutions reported holding it in 13F filings for Q2 2026, worth $1.79B in total; no superinvestor holds it.

13F holders, Q1 2022

Institutional positions in Zymeworks Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
120
+6 vs. Q4 2021
Shares held
50.0M
+7.63M (+18.0%) vs. Q4 2021
Total value
$327.3M
−$366.6M (−52.8%) vs. Q4 2021
New holders
29
53 more added
Sold out
23
19 more reduced

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ZYME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 120 institutions
Q1 2021: 125 institutionsQ2 2021: 109 institutionsQ3 2021: 123 institutionsQ4 2021: 114 institutionsQ1 2022: 120 institutionsQ2 2022: 114 institutionsQ3 2022: 91 institutionsQ4 2022: 96 institutionsQ1 2023: 116 institutionsQ2 2023: 137 institutionsQ3 2023: 140 institutionsQ4 2023: 157 institutionsQ1 2024: 171 institutionsQ2 2024: 164 institutionsQ3 2024: 163 institutionsQ4 2024: 174 institutionsQ1 2025: 186 institutionsQ2 2025: 182 institutionsQ3 2025: 184 institutionsQ4 2025: 210 institutionsQ1 2026: 212 institutionsQ2 2026: 202 institutions
Value heldQ1 2022: $327.3M
Q1 2021: $1.12BQ2 2021: $1.20BQ3 2021: $1.07BQ4 2021: $693.9MQ1 2022: $327.3MQ2 2022: $253.3MQ3 2022: $293.7MQ4 2022: $449.9MQ1 2023: $512.6MQ2 2023: $547.9MQ3 2023: $395.5MQ4 2023: $674.0MQ1 2024: $713.0MQ2 2024: $580.6MQ3 2024: $834.7MQ4 2024: $973.2MQ1 2025: $840.9MQ2 2025: $949.0MQ3 2025: $1.26BQ4 2025: $1.88BQ1 2026: $1.76BQ2 2026: $1.79B
Institutions holding ZYME and their total value by quarter
QuarterHoldersValue
Q2 2026202$1.79B
Q1 2026212$1.76B
Q4 2025210$1.88B
Q3 2025184$1.26B
Q2 2025182$949.0M
Q1 2025186$840.9M
Q4 2024174$973.2M
Q3 2024163$834.7M
Q2 2024164$580.6M
Q1 2024171$713.0M
Q4 2023157$674.0M
Q3 2023140$395.5M
Q2 2023137$547.9M
Q1 2023116$512.6M
Q4 202296$449.9M
Q3 202291$293.7M
Q2 2022114$253.3M
Q1 2022120$327.3M
Q4 2021114$693.9M
Q3 2021123$1.07B
Q2 2021109$1.20B
Q1 2021125$1.12B

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding Zymeworks Inc.; share changes are against Q4 2021.

Institutions holding ZYME in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Armistice Capital, LLC5,760,000$37.7M1.07%+4,509,803+360.7%Added
Eventide Asset Management, LLC5,380,200$35.2M0.55%+2,561,065+90.8%Added
Perceptive Advisors LLC5,325,615$34.9M0.72%+1,645,770+44.7%Added
Credit Suisse AG2,475,002$16.2M0.01%+11,027+0.4%Added
Morgan Stanley2,334,028$15.3M0.00%+219,456+10.4%Added
Woodline Partners LP2,216,062$14.5M0.24%+957,661+76.1%Added
Redmile Group, LLC2,114,197$13.8M0.43%+1,239,800+141.8%Added
Camber Capital Management LP2,000,000$13.1M0.47%+1,200,000+150.0%Added
Baker Bros. Advisors LP1,708,472$11.2M0.06%00.0%Unchanged
BNP PARIBAS ASSET MANAGEMENT Holding S.A.1,291,653$8.46M0.03%+145,935+12.7%Added
Millennium Management LLC1,184,831$7.76M0.01%+669,916+130.1%Added
Wellington Management Group LLP1,175,788$7.70M0.00%−1,681,198−58.8%Reduced
Alyeska Investment Group, L.P.1,164,103$7.63M0.08%+493,763+73.7%Added
Maven Securities LTD1,010,127$6.62M1.37%+1,010,127New
BlackRock Inc.973,451$6.38M0.00%+162,353+20.0%Added
Samsara BioCapital, LLC970,987$6.36M1.61%+970,987New
Two Sigma Investments, LP791,148$5.18M0.02%+791,148New
Point72 Asset Management, L.P.765,500$5.01M0.02%+15,000+2.0%Added
JPMorgan Chase & Co686,784$4.50M0.00%+610,892+804.9%Added
Franklin Resources Inc600,000$3.93M0.00%−657,090−52.3%Reduced
Renaissance Technologies LLC547,900$3.59M0.00%+385,300+237.0%Added
FMR LLC547,078$3.58M0.00%−2,944,469−84.3%Reduced
Goldman Sachs Group Inc520,436$3.41M0.00%−1,998,572−79.3%Reduced
Voloridge Investment Management, LLC480,376$3.15M0.02%+348,219+263.5%Added
Artal Group S.A.450,000$2.95M0.12%00.0%Unchanged
Timelo Investment Management Inc.439,340$2.88M2.44%+203,442+86.2%Added
D. E. Shaw & Co., Inc.437,491$2.87M0.00%+405,408+1,263.6%Added
Vanguard Group Inc413,278$2.71M0.00%+179,461+76.8%Added
UBS Asset Management Americas Inc336,008$2.20M0.00%−74,207−18.1%Reduced
National Bank of Canada318,555$2.09M0.01%+317,955+52,992.5%Added
Two Sigma Advisers, LP304,300$1.99M0.01%+269,300+769.4%Added
BNP Paribas Arbitrage, SA286,928$1.88M0.00%+177,647+162.6%Added
Vivo Capital, LLC286,064$1.87M0.13%00.0%Unchanged
Citadel Advisors LLC283,904$1.86M0.00%+229,379+420.7%Added
Walleye Capital LLC276,307$1.81M0.05%+276,307New
Platinum Investment Management Ltd235,299$1.54M0.05%00.0%Unchanged
Silvercrest Asset Management Group LLC222,627$1.46M0.01%+2,092+0.9%Added
Raymond James & Associates169,485$1.11M0.00%−58,939−25.8%Reduced
Norges Bank168,700$1.10M0.00%00.0%Unchanged
Ci Investments Inc.159,050$1.04M0.00%+78,242+96.8%Added
Russell Investments Group, Ltd.149,892$980.0K0.00%+35,264+30.8%Added
Kennedy Capital Management, Inc.142,968$936.0K0.02%−57,070−28.5%Reduced
Graham Capital Management, L.P.137,601$901.0K0.04%+137,601New
State Street Corp137,271$899.0K0.00%+12,061+9.6%Added
Brookfield Asset Management Inc.127,130$833.0K0.00%+127,130New
Deutsche Bank AG126,759$830.0K0.00%+1,241+1.0%Added
Susquehanna International Group, LLP125,680$823.0K0.00%−23,925−16.0%Reduced
Qube Research & Technologies Ltd123,356$808.0K0.01%+123,356New
Laurion Capital Management LP120,000$786.0K0.02%+120,000New
Parkman Healthcare Partners LLC119,286$781.0K0.23%+77,661+186.6%Added
Swiss National Bank118,500$776.0K0.00%+37,100+45.6%Added
PDT Partners, LLC110,673$725.0K0.06%+13,252+13.6%Added
Occudo Quantitative Strategies LP108,285$709.0K0.06%+108,285New
Picton Mahoney Asset Management87,146$572.0K0.02%−12,639−12.7%Reduced
Algert Global LLC82,815$542.0K0.04%+61,265+284.3%Added
Wells Fargo & Company81,706$535.0K0.00%+55,233+208.6%Added
Group One Trading, L.P.80,722$529.0K0.01%+74,600+1,218.6%Added
Schonfeld Strategic Advisors LLC75,200$493.0K0.01%+75,200New
Raymond James Financial Services Advisors, Inc.71,967$471.0K0.00%+7,868+12.3%Added
Ergoteles LLC67,149$440.0K0.02%+67,149New
Man Group plc64,400$422.0K0.00%+64,400New
Marshall Wace, LLP61,735$405.0K0.00%+61,735New
Marathon Capital Management47,840$313.0K0.09%+3,500+7.9%Added
Invesco Ltd.46,540$305.0K0.00%+46,540New
Gsa Capital Partners LLP46,149$302.0K0.04%+31,652+218.3%Added
Northern Trust Corp45,800$300.0K0.00%−634−1.4%Reduced
Jump Financial, LLC44,348$290.0K0.01%+44,348New
California State Teachers Retirement System42,397$278.0K0.00%+10,900+34.6%Added
Simplex Trading, LLC40,844$267.0K0.01%+40,844New
Nuveen Asset Management, LLC36,322$254.0K0.00%+3,008+9.0%Added
Walleye Trading LLC34,934$229.0K0.00%+34,934New
Dynamic Technology Lab Private Ltd30,245$198.0K0.02%+30,245New
Journey Strategic Wealth LLC28,846$189.0K0.02%00.0%Unchanged
Commonwealth Equity Services, LLC25,744$168.0K0.00%+483+1.9%Added
Bank of Montreal24,872$167.0K0.00%+4,103+19.8%Added
Jane Street Group, LLC23,822$156.0K0.00%+8,032+50.9%Added
Golden State Equity Partners23,043$151.0K0.08%+5,250+29.5%Added
Guggenheim Capital LLC20,713$136.0K0.00%+20,713New
Allspring Global Investments Holdings, LLC18,294$119.0K0.00%00.0%Unchanged
Legal & General Group Plc17,070$112.0K0.00%+2,500+17.2%Added
ExodusPoint Capital Management, LP16,599$109.0K0.00%−38,573−69.9%Reduced
Fox Run Management, L.L.C.16,477$108.0K0.06%+16,477New
Values First Advisors, Inc.15,935$104.0K0.07%+15,935New
Cubist Systematic Strategies, LLC15,520$102.0K0.00%−29,103−65.2%Reduced
Arizona State Retirement System13,554$89.0K0.00%+13,554New
AQR Capital Management LLC12,445$82.0K0.00%+12,445New
Prelude Capital Management, LLC11,702$77.0K0.00%+20.0%Added
Handelsbanken Fonder AB11,500$75.0K0.00%00.0%Unchanged
Prospera Financial Services Inc10,972$72.0K0.00%+10,972New
Janney Montgomery Scott LLC10,267$67.0K0.00%00.0%Unchanged
Teacher Retirement System of Texas10,225$67.0K0.00%+10,225New
Compagnie Lombard Odier SCmA10,000$66.0K0.00%+7,000+233.3%Added
Lazard Asset Management LLC10,117$66.0K0.00%+10,117New
First Republic Investment Management, Inc.10,000$66.0K0.00%+10,000New
Virtus ETF Advisers LLC9,749$64.0K0.03%−575−5.6%Reduced
Ensign Peak Advisors, Inc8,270$54.0K0.00%00.0%Unchanged
Public Employees Retirement Association of Colorado7,991$52.0K0.00%00.0%Unchanged
Quantbot Technologies LP6,482$42.0K0.00%+6,482New
Bank of America Corp4,708$31.0K0.00%−2,659,635−99.8%Reduced
Skandinaviska Enskilda Banken AB (publ)4,725$31.0K0.00%+4,725New