Zymeworks Inc.
ZYME- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001937653
No open-market purchases or sales by Zymeworks Inc. insiders were filed in the last 90 days; 202 institutions reported holding it in 13F filings for Q2 2026, worth $1.79B in total; no superinvestor holds it.
13F holders, Q4 2024
Institutional positions in Zymeworks Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 174
- +13 vs. Q3 2024
- Shares held
- 66.5M
- −22.8K (0.0%) vs. Q3 2024
- Total value
- $973.2M
- +$139.4M (+16.7%) vs. Q3 2024
- New holders
- 33
- 47 more added
- Sold out
- 20
- 61 more reduced
2 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ZYME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 202 | $1.79B |
| Q1 2026 | 212 | $1.76B |
| Q4 2025 | 210 | $1.88B |
| Q3 2025 | 184 | $1.26B |
| Q2 2025 | 182 | $949.0M |
| Q1 2025 | 186 | $840.9M |
| Q4 2024 | 174 | $973.2M |
| Q3 2024 | 163 | $834.7M |
| Q2 2024 | 164 | $580.6M |
| Q1 2024 | 171 | $713.0M |
| Q4 2023 | 157 | $674.0M |
| Q3 2023 | 140 | $395.5M |
| Q2 2023 | 137 | $547.9M |
| Q1 2023 | 116 | $512.6M |
| Q4 2022 | 96 | $449.9M |
| Q3 2022 | 91 | $293.7M |
| Q2 2022 | 114 | $253.3M |
| Q1 2022 | 120 | $327.3M |
| Q4 2021 | 114 | $693.9M |
| Q3 2021 | 123 | $1.07B |
| Q2 2021 | 109 | $1.20B |
| Q1 2021 | 125 | $1.12B |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Zymeworks Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| EcoR1 Capital, LLC | 15,028,079 | $220.0M | 8.81% | +1,590,606+11.8% | Added |
| Redmile Group, LLC | 4,840,463 | $70.9M | 4.94% | −261,448−5.1% | Reduced |
| BVF Inc | 4,308,935 | $63.1M | 2.14% | −299,000−6.5% | Reduced |
| Morgan Stanley | 4,201,437 | $61.5M | 0.00% | −905,432−17.7% | Reduced |
| BlackRock, Inc. | 4,184,956 | $61.3M | 0.00% | −78,639−1.8% | Reduced |
| Rubric Capital Management LP | 3,917,331 | $57.3M | 1.04% | 00.0% | Unchanged |
| Vanguard Group Inc | 2,493,288 | $36.5M | 0.00% | −365,226−12.8% | Reduced |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 2,137,653 | $31.3M | 0.08% | +192,162+9.9% | Added |
| Perceptive Advisors LLC | 2,130,020 | $31.2M | 0.87% | −50,000−2.3% | Reduced |
| Deutsche Bank AG | 1,546,772 | $22.6M | 0.01% | +17,849+1.2% | Added |
| UBS Asset Management Americas Inc | 1,365,111 | $20.0M | 0.00% | −158,973−10.4% | Reduced |
| Farallon Capital Management, L.L.C. | 1,329,974 | $19.5M | 0.10% | −31,026−2.3% | Reduced |
| Nextech Invest AG | 1,113,946 | $16.3M | 2.65% | 00.0% | Unchanged |
| Tang Capital Management LLC | 1,100,000 | $16.1M | 1.07% | 00.0% | Unchanged |
| State Street Corp | 1,084,961 | $15.9M | 0.00% | −86,816−7.4% | Reduced |
| Samsara BioCapital, LLC | 1,000,000 | $14.6M | 2.01% | 00.0% | Unchanged |
| Dimensional Fund Advisors LP | 972,742 | $14.2M | 0.00% | +123,240+14.5% | Added |
| Prosight Management, LP | 820,000 | $12.0M | 3.36% | −97,599−10.6% | Reduced |
| Bridgeway Capital Management, LLC | 759,653 | $11.1M | 0.25% | +17,092+2.3% | Added |
| Geode Capital Management, LLC | 689,884 | $10.1M | 0.00% | −24,031−3.4% | Reduced |
| Assenagon Asset Management S.A. | 642,251 | $9.40M | 0.02% | +311,107+93.9% | Added |
| Blackstone Group Inc. | 569,715 | $8.34M | 0.04% | +544,633+2,171.4% | Added |
| Walleye Capital LLC | 452,804 | $6.63M | 0.06% | +452,804 | New |
| Granahan Investment Management Inc | 411,120 | $6.02M | 0.25% | −202,383−33.0% | Reduced |
| Northern Trust Corp | 394,830 | $5.78M | 0.00% | +23,903+6.4% | Added |
| Jupiter Asset Management Ltd | 369,499 | $5.41M | 0.05% | −57,445−13.5% | Reduced |
| Jacobs Levy Equity Management, Inc | 356,168 | $5.21M | 0.02% | −166,472−31.9% | Reduced |
| Empowered Funds, LLC | 352,753 | $5.16M | 0.08% | +17,092+5.1% | Added |
| Schroder Investment Management Group | 337,161 | $4.89M | 0.00% | +337,161 | New |
| Point72 Asset Management, L.P. | 330,127 | $4.83M | 0.01% | +280,544+565.8% | Added |
| Platinum Investment Management Ltd | 306,460 | $4.49M | 0.26% | −21,062−6.4% | Reduced |
| Renaissance Technologies LLC | 285,700 | $4.18M | 0.01% | +101,100+54.8% | Added |
| Silvercrest Asset Management Group LLC | 282,345 | $4.13M | 0.03% | −2,770−1.0% | Reduced |
| Goldman Sachs Group Inc | 249,960 | $3.66M | 0.00% | −1,517−0.6% | Reduced |
| Acadian Asset Management LLC | 230,970 | $3.38M | 0.01% | −214,806−48.2% | Reduced |
| Hillsdale Investment Management Inc. | 230,025 | $3.37M | 0.17% | +230,025 | New |
| Barclays PLC | 220,890 | $3.23M | 0.00% | +66,506+43.1% | Added |
| Wellington Management Group LLP | 219,098 | $3.21M | 0.00% | −24,091−9.9% | Reduced |
| Panagora Asset Management Inc | 214,338 | $3.14M | 0.01% | +113,472+112.5% | Added |
| Nuveen Asset Management, LLC | 207,023 | $3.03M | 0.00% | +886+0.4% | Added |
| Picton Mahoney Asset Management | 206,569 | $3.02M | 0.11% | −38,087−15.6% | Reduced |
| Norges Bank | 201,700 | $2.95M | 0.00% | 00.0% | Unchanged |
| Vestal Point Capital, LP | 185,000 | $2.71M | 0.16% | −430,000−69.9% | Reduced |
| Federated Hermes, Inc. | 181,626 | $2.66M | 0.01% | +3,367+1.9% | Added |
| UBS Group AG | 166,896 | $2.44M | 0.00% | +31,341+23.1% | Added |
| Wells Fargo & Company | 164,058 | $2.40M | 0.00% | −13,352−7.5% | Reduced |
| Kennedy Capital Management, Inc. | 139,953 | $2.05M | 0.05% | −3,627−2.5% | Reduced |
| O'Shaughnessy Asset Management, LLC | 132,577 | $1.94M | 0.02% | −12,271−8.5% | Reduced |
| Charles Schwab Investment Management Inc | 131,306 | $1.92M | 0.00% | −1,492−1.1% | Reduced |
| Ameriprise Financial Inc | 121,526 | $1.78M | 0.00% | −15,800−11.5% | Reduced |
| Bank of New York Mellon Corp | 120,683 | $1.77M | 0.00% | −129,308−51.7% | Reduced |
| JPMorgan Chase & Co | 111,983 | $1.64M | 0.00% | +72,703+185.1% | Added |
| Rhumbline Advisers | 103,876 | $1.52M | 0.00% | +15,920+18.1% | Added |
| Trexquant Investment LP | 101,996 | $1.49M | 0.02% | +101,996 | New |
| Susquehanna Fundamental Investments, LLC | 97,553 | $1.43M | 0.02% | +97,553 | New |
| North Growth Management Ltd. | 97,000 | $1.42M | 0.27% | 00.0% | Unchanged |
| HRT Financial LP | 95,974 | $1.41M | 0.01% | +47,166+96.6% | Added |
| Swiss National Bank | 90,200 | $1.32M | 0.00% | 00.0% | Unchanged |
| Citigroup Inc | 83,136 | $1.22M | 0.00% | +3,246+4.1% | Added |
| Credit Agricole S A | 75,000 | $1.10M | 0.00% | 00.0% | Unchanged |
| Ritholtz Wealth Management | 74,466 | $1.09M | 0.03% | +4,297+6.1% | Added |
| Invesco Ltd. | 69,382 | $1.02M | 0.00% | −93,657−57.4% | Reduced |
| Acuta Capital Partners, LLC | 67,240 | $984.4K | 0.99% | +67,240 | New |
| State of Wisconsin Investment Board | 65,381 | $957.2K | 0.00% | −19,777−23.2% | Reduced |
| Stifel Financial Corp | 64,330 | $941.8K | 0.00% | −9,324−12.7% | Reduced |
| Fisher Asset Management, LLC | 63,600 | $931.1K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 60,926 | $893.0K | 0.00% | −952−1.5% | Reduced |
| Raymond James Financial Inc | 60,642 | $887.8K | 0.00% | +60,642 | New |
| Voya Investment Management LLC | 59,514 | $871.3K | 0.00% | +40,172+207.7% | Added |
| Citadel Advisors LLC | 58,358 | $854.4K | 0.00% | +37,550+180.5% | Added |
| Envestnet Asset Management Inc | 54,090 | $791.9K | 0.00% | −11,588−17.6% | Reduced |
| Victory Capital Management Inc | 51,580 | $755.1K | 0.00% | −2,810−5.2% | Reduced |
| Susquehanna International Group, LLP | 51,516 | $754.2K | 0.00% | +35,130+214.4% | Added |
| Public Employees Retirement System of Ohio | 50,583 | $740.5K | 0.00% | −10,400−17.1% | Reduced |
| Alliancebernstein L.P. | 50,030 | $732.4K | 0.00% | 00.0% | Unchanged |
| STRS Ohio | 49,000 | $717.4K | 0.00% | +49,000 | New |
| Jump Financial, LLC | 48,612 | $711.7K | 0.01% | +48,612 | New |
| Legal & General Group Plc | 47,082 | $689.3K | 0.00% | +7,511+19.0% | Added |
| Russell Investments Group, Ltd. | 44,945 | $658.0K | 0.00% | −4,826−9.7% | Reduced |
| California State Teachers Retirement System | 43,783 | $641.0K | 0.00% | −383−0.9% | Reduced |
| Voloridge Investment Management, LLC | 43,708 | $639.9K | 0.00% | +43,708 | New |
| American Century Companies Inc | 39,942 | $584.8K | 0.00% | +39,942 | New |
| Tejara Capital Ltd | 38,537 | $564.2K | 0.37% | +38,537 | New |
| Polar Asset Management Partners Inc. | 36,000 | $527.0K | 0.01% | +36,000 | New |
| MetLife Investment Management | 33,946 | $497.0K | 0.00% | +2,053+6.4% | Added |
| Intech Investment Management LLC | 33,858 | $495.7K | 0.00% | +12,698+60.0% | Added |
| XTX Topco Ltd | 33,702 | $493.4K | 0.04% | +33,702 | New |
| Bank of America Corp | 31,700 | $464.1K | 0.00% | −38,030−54.5% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 30,958 | $453.2K | 0.00% | +293+1.0% | Added |
| Commonwealth Equity Services, LLC | 30,960 | $453.0K | 0.00% | +4,294+16.1% | Added |
| Cresset Asset Management, LLC | 30,806 | $451.0K | 0.00% | −8,583−21.8% | Reduced |
| Journey Strategic Wealth LLC | 28,897 | $423.1K | 0.02% | 00.0% | Unchanged |
| Massachusetts Financial Services Co | 27,385 | $400.9K | 0.00% | −52,471−65.7% | Reduced |
| Corebridge Financial, Inc. | 27,115 | $397.0K | 0.00% | −2,763−9.2% | Reduced |
| SG Americas Securities, LLC | 26,782 | $392.0K | 0.00% | +6,239+30.4% | Added |
| AQR Capital Management LLC | 26,074 | $381.7K | 0.00% | +1,212+4.9% | Added |
| Bank of Montreal | 25,948 | $379.9K | 0.00% | −2,637−9.2% | Reduced |
| Jane Street Group, LLC | 23,127 | $338.6K | 0.00% | −57,199−71.2% | Reduced |
| Schonfeld Strategic Advisors LLC | 22,800 | $333.8K | 0.00% | +22,800 | New |
| FMR LLC | 21,966 | $321.6K | 0.00% | +18,630+558.5% | Added |