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Zymeworks Inc.

ZYME
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001937653

No open-market purchases or sales by Zymeworks Inc. insiders were filed in the last 90 days; 202 institutions reported holding it in 13F filings for Q2 2026, worth $1.79B in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Zymeworks Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
174
+13 vs. Q3 2024
Shares held
66.5M
−22.8K (0.0%) vs. Q3 2024
Total value
$973.2M
+$139.4M (+16.7%) vs. Q3 2024
New holders
33
47 more added
Sold out
20
61 more reduced

2 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ZYME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 174 institutions
Q1 2021: 125 institutionsQ2 2021: 109 institutionsQ3 2021: 123 institutionsQ4 2021: 114 institutionsQ1 2022: 120 institutionsQ2 2022: 114 institutionsQ3 2022: 91 institutionsQ4 2022: 96 institutionsQ1 2023: 116 institutionsQ2 2023: 137 institutionsQ3 2023: 140 institutionsQ4 2023: 157 institutionsQ1 2024: 171 institutionsQ2 2024: 164 institutionsQ3 2024: 163 institutionsQ4 2024: 174 institutionsQ1 2025: 186 institutionsQ2 2025: 182 institutionsQ3 2025: 184 institutionsQ4 2025: 210 institutionsQ1 2026: 212 institutionsQ2 2026: 202 institutions
Value heldQ4 2024: $973.2M
Q1 2021: $1.12BQ2 2021: $1.20BQ3 2021: $1.07BQ4 2021: $693.9MQ1 2022: $327.3MQ2 2022: $253.3MQ3 2022: $293.7MQ4 2022: $449.9MQ1 2023: $512.6MQ2 2023: $547.9MQ3 2023: $395.5MQ4 2023: $674.0MQ1 2024: $713.0MQ2 2024: $580.6MQ3 2024: $834.7MQ4 2024: $973.2MQ1 2025: $840.9MQ2 2025: $949.0MQ3 2025: $1.26BQ4 2025: $1.88BQ1 2026: $1.76BQ2 2026: $1.79B
Institutions holding ZYME and their total value by quarter
QuarterHoldersValue
Q2 2026202$1.79B
Q1 2026212$1.76B
Q4 2025210$1.88B
Q3 2025184$1.26B
Q2 2025182$949.0M
Q1 2025186$840.9M
Q4 2024174$973.2M
Q3 2024163$834.7M
Q2 2024164$580.6M
Q1 2024171$713.0M
Q4 2023157$674.0M
Q3 2023140$395.5M
Q2 2023137$547.9M
Q1 2023116$512.6M
Q4 202296$449.9M
Q3 202291$293.7M
Q2 2022114$253.3M
Q1 2022120$327.3M
Q4 2021114$693.9M
Q3 2021123$1.07B
Q2 2021109$1.20B
Q1 2021125$1.12B

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Zymeworks Inc.; share changes are against Q3 2024.

Institutions holding ZYME in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Qube Research & Technologies Ltd21,868$320.1K0.00%+21,868New
Price T Rowe Associates Inc21,583$316.0K0.00%+3,235+17.6%Added
Manufacturers Life Insurance Company, The20,958$306.8K0.00%−1,089−4.9%Reduced
D. E. Shaw & Co., Inc.20,840$305.1K0.00%−942−4.3%Reduced
Prudential Financial Inc19,660$287.8K0.00%+19,660New
Zurcher Kantonalbank (Zurich Cantonalbank)19,611$287.1K0.00%+2,529+14.8%Added
ProShare Advisors LLC18,623$272.6K0.00%−10,889−36.9%Reduced
Janus Henderson Group PLC18,200$266.2K0.00%00.0%Unchanged
Verition Fund Management LLC15,814$231.5K0.00%+15,814New
State Board of Administration of Florida Retirement System15,340$224.6K0.00%00.0%Unchanged
Monaco Asset Management SAM15,000$219.6K0.10%−285,000−95.0%Reduced
China Universal Asset Management Co., Ltd.14,605$213.8K0.02%+940+6.9%Added
One Wealth Advisors, LLC13,979$204.7K0.03%−10,366−42.6%Reduced
Teacher Retirement System of Texas13,743$201.0K0.00%+2,216+19.2%Added
Arizona State Retirement System13,412$196.4K0.00%+178+1.3%Added
Exchange Traded Concepts, LLC13,386$196.0K0.00%00.0%Unchanged
New York State Common Retirement Fund13,371$195.8K0.00%+4,000+42.7%Added
Shell Asset Management Co12,357$181.0K0.01%00.0%Unchanged
Police & Firemen's Retirement System of New Jersey11,669$170.8K0.00%+11,669New
James Investment Research Inc10,578$154.9K0.02%00.0%Unchanged
KLP Kapitalforvaltning AS10,300$150.8K0.00%+10,300New
Janney Montgomery Scott LLC10,267$150.0K0.00%00.0%Unchanged
TPG Financial Advisors, LLC10,017$146.6K0.06%−1,000−9.1%Reduced
Jain Global LLC10,010$146.5K0.00%+10,010New
Tower Research Capital LLC (TRC)9,704$142.1K0.00%+7,518+343.9%Added
BNP Paribas Arbitrage, SA7,363$107.8K0.00%+7,363New
Compagnie Lombard Odier SCmA7,000$102.5K0.00%−3,000−30.0%Reduced
Virtus ETF Advisers LLC5,633$82.5K0.03%−4,481−44.3%Reduced
Ameritas Investment Partners, Inc.5,616$82.2K0.00%00.0%Unchanged
Northwest & Ethical Investments L.P.5,471$80.0K0.00%−900−14.1%Reduced
Clearstead Advisors, LLC5,000$73.2K0.00%00.0%Unchanged
DekaBank Deutsche Girozentrale3,843$55.0K0.00%00.0%Unchanged
Quest Partners LLC2,808$41.1K0.01%+2,324+480.2%Added
Mirae Asset Global Investments Co., Ltd.2,295$33.3K0.00%−275−10.7%Reduced
Amalgamated Bank1,799$26.0K0.00%00.0%Unchanged
Sterling Capital Management LLC1,719$25.2K0.00%+1,524+781.5%Added
GF Fund Management Co. Ltd.1,446$21.2K0.00%+1,446New
Simplex Trading, LLC1,087$15.0K0.00%−443−29.0%Reduced
Curio Wealth, LLC1,000$14.6K0.01%+1,000New
Group One Trading, L.P.800$11.7K0.00%−29,041−97.3%Reduced
Advisor Group Holdings, Inc.717$10.5K0.00%−132−15.5%Reduced
Skopos Labs, Inc.589$8.62K0.00%+589New
National Bank of Canada548$8.02K0.00%−21−3.7%Reduced
GAMMA Investing LLC533$7.80K0.00%+100+23.1%Added
US Bancorp488$7.14K0.00%−416−46.0%Reduced
Truvestments Capital LLC434$6.35K0.00%+175+67.6%Added
Lindbrook Capital, LLC371$5.43K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC332$4.86K0.00%−17−4.9%Reduced
Parallel Advisors, LLC329$4.82K0.00%00.0%Unchanged
TD Waterhouse Canada Inc.311$4.54K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.284$4.16K0.00%+280+7,000.0%Added
HighMark Wealth Management LLC280$4.10K0.00%00.0%Unchanged
Daiwa Securities Group Inc.286$4.00K0.00%00.0%Unchanged
Smartleaf Asset Management LLC243$3.52K0.00%+101+71.1%Added
CWM, LLC193$3.00K0.00%+121+168.1%Added
SRS Capital Advisors, Inc.169$2.48K0.00%−47−21.8%Reduced
Cornerstone Planning Group LLC161$2.33K0.00%00.0%Unchanged
Farther Finance Advisors, LLC150$2.20K0.00%00.0%Unchanged
Eagle Bay Advisors LLC110$1.61K0.00%00.0%Unchanged
Aster Capital Management (DIFC) Ltd70$1.02K0.00%−686−90.7%Reduced
Federation des caisses Desjardins du Quebec60$8780.00%+60New
Creative Planning57$8340.00%+57New
Steward Partners Investment Advisory, LLC53$7760.00%00.0%Unchanged
Amundi52$7350.00%+52New
Rothschild Investment LLC50$7320.00%−10−16.7%Reduced
Allworth Financial LP34$4990.00%00.0%Unchanged
WR Wealth Planners, LLC28$4100.00%00.0%Unchanged
Richards, Merrill & Peterson, Inc.20$2930.00%+20New
CoreCap Advisors, LLC18$2640.00%00.0%Unchanged
EverSource Wealth Advisors, LLC10$1460.00%+10New
SBI Securities Co., Ltd.10$1460.00%+10New
Innovative Advisory Group, LLC8$1170.00%+8New
IFP Advisors, Inc0$590.00%0New
Covestor Ltd27$00.00%+9+50.0%Added
Arrowstreet Capital, Limited Partnership0$00.00%−407,771−100.0%Sold out
Healthcare of Ontario Pension Plan Trust Fund0$00.00%−235,900−100.0%Sold out
Marshall Wace, LLP0$00.00%−209,765−100.0%Sold out
J. Goldman & Co LP0$00.00%−119,956−100.0%Sold out
Deerfield Management Company, L.P. (Series C)0$00.00%−49,546−100.0%Sold out
Caxton Associates LP0$00.00%−45,810−100.0%Sold out
Squarepoint Ops LLC0$00.00%−33,438−100.0%Sold out
Susquehanna Portfolio Strategies, LLC0$00.00%−24,671−100.0%Sold out
Fox Run Management, L.L.C.0$00.00%−16,465−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−11,724−100.0%Sold out
Tocqueville Asset Management L.P.0$00.00%−10,679−100.0%Sold out
Virtus Investment Advisers, Inc.0$00.00%−9,819−100.0%Sold out
Lazard Asset Management LLC0$00.00%−9,561−100.0%Sold out
nVerses Capital, LLC0$00.00%−6,300−100.0%Sold out
Virtus Fund Advisers, LLC0$00.00%−1,908−100.0%Sold out
Allspring Global Investments Holdings, LLC0$00.00%−696−100.0%Sold out
Stonehage Fleming Financial Services Holdings Ltd0$00.00%−550−100.0%Sold out
Frazier Financial Advisors, LLC0$00.00%−226−100.0%Sold out
Asset Dedication, LLC0$00.00%−47−100.0%Sold out
Capital Performance Advisors LLP0$00.00%−15−100.0%Sold out
Raymond James Financial Services Advisors, Inc.––––Not filed
Raymond James & Associates––––Not filed