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Zymeworks Inc.

ZYME
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001937653

No open-market purchases or sales by Zymeworks Inc. insiders were filed in the last 90 days; 202 institutions reported holding it in 13F filings for Q2 2026, worth $1.79B in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Zymeworks Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
114
−7 vs. Q3 2021
Shares held
42.3M
+5.53M (+15.0%) vs. Q3 2021
Total value
$693.9M
−$374.9M (−35.1%) vs. Q3 2021
New holders
22
43 more added
Sold out
29
26 more reduced

2 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ZYME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 114 institutions
Q1 2021: 125 institutionsQ2 2021: 109 institutionsQ3 2021: 123 institutionsQ4 2021: 114 institutionsQ1 2022: 120 institutionsQ2 2022: 114 institutionsQ3 2022: 91 institutionsQ4 2022: 96 institutionsQ1 2023: 116 institutionsQ2 2023: 137 institutionsQ3 2023: 140 institutionsQ4 2023: 157 institutionsQ1 2024: 171 institutionsQ2 2024: 164 institutionsQ3 2024: 163 institutionsQ4 2024: 174 institutionsQ1 2025: 186 institutionsQ2 2025: 182 institutionsQ3 2025: 184 institutionsQ4 2025: 210 institutionsQ1 2026: 212 institutionsQ2 2026: 202 institutions
Value heldQ4 2021: $693.9M
Q1 2021: $1.12BQ2 2021: $1.20BQ3 2021: $1.07BQ4 2021: $693.9MQ1 2022: $327.3MQ2 2022: $253.3MQ3 2022: $293.7MQ4 2022: $449.9MQ1 2023: $512.6MQ2 2023: $547.9MQ3 2023: $395.5MQ4 2023: $674.0MQ1 2024: $713.0MQ2 2024: $580.6MQ3 2024: $834.7MQ4 2024: $973.2MQ1 2025: $840.9MQ2 2025: $949.0MQ3 2025: $1.26BQ4 2025: $1.88BQ1 2026: $1.76BQ2 2026: $1.79B
Institutions holding ZYME and their total value by quarter
QuarterHoldersValue
Q2 2026202$1.79B
Q1 2026212$1.76B
Q4 2025210$1.88B
Q3 2025184$1.26B
Q2 2025182$949.0M
Q1 2025186$840.9M
Q4 2024174$973.2M
Q3 2024163$834.7M
Q2 2024164$580.6M
Q1 2024171$713.0M
Q4 2023157$674.0M
Q3 2023140$395.5M
Q2 2023137$547.9M
Q1 2023116$512.6M
Q4 202296$449.9M
Q3 202291$293.7M
Q2 2022114$253.3M
Q1 2022120$327.3M
Q4 2021114$693.9M
Q3 2021123$1.07B
Q2 2021109$1.20B
Q1 2021125$1.12B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Zymeworks Inc.; share changes are against Q3 2021.

Institutions holding ZYME in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Perceptive Advisors LLC3,679,845$60.3M0.93%00.0%Unchanged
FMR LLC3,491,547$57.2M0.00%+12,618+0.4%Added
Wellington Management Group LLP2,856,986$46.8M0.01%+2,257,851+376.9%Added
Eventide Asset Management, LLC2,819,135$46.2M0.59%−910,054−24.4%Reduced
Bank of America Corp2,664,343$43.7M0.00%+2,636,728+9,548.2%Added
Goldman Sachs Group Inc2,519,008$41.3M0.01%+2,240,800+805.4%Added
Credit Suisse AG2,463,975$40.4M0.03%+117,457+5.0%Added
Morgan Stanley2,114,572$34.7M0.00%−181,850−7.9%Reduced
Price T Rowe Associates Inc1,714,905$28.1M0.00%+17,592+1.0%Added
Baker Bros. Advisors LP1,708,472$28.0M0.14%00.0%Unchanged
Woodline Partners LP1,258,401$20.6M0.30%+1,258,401New
Franklin Resources Inc1,257,090$20.6M0.01%+560.0%Added
Armistice Capital, LLC1,250,197$20.5M0.50%−1,273,803−50.5%Reduced
BNP PARIBAS ASSET MANAGEMENT Holding S.A.1,145,718$18.8M0.06%+296,993+35.0%Added
Redmile Group, LLC874,397$14.3M0.33%−7,700−0.9%Reduced
BlackRock Inc.811,098$13.3M0.00%+32,799+4.2%Added
Camber Capital Management LP800,000$13.1M0.51%+50,000+6.7%Added
Point72 Asset Management, L.P.750,500$12.3M0.05%+750,500New
Alyeska Investment Group, L.P.670,340$11.0M0.13%+374,417+126.5%Added
Cormorant Asset Management, LP600,000$9.83M0.58%−350,000−36.8%Reduced
Millennium Management LLC514,915$8.44M0.01%+275,102+114.7%Added
Artal Group S.A.450,000$7.38M0.22%00.0%Unchanged
UBS Asset Management Americas Inc410,215$6.72M0.00%−257,774−38.6%Reduced
Sofinnova Investments, Inc.392,712$6.44M0.41%−17,907−4.4%Reduced
Thrivent Financial for Lutherans287,140$4.71M0.01%−81,963−22.2%Reduced
Vivo Capital, LLC286,064$4.69M0.28%00.0%Unchanged
SG Americas Securities, LLC269,151$4.41M0.03%+49,049+22.3%Added
Timelo Investment Management Inc.235,898$3.87M2.07%+235,898New
Platinum Investment Management Ltd235,299$3.86M0.11%+79,887+51.4%Added
Vanguard Group Inc233,817$3.83M0.00%+62,261+36.3%Added
Raymond James & Associates228,424$3.74M0.00%−65,398−22.3%Reduced
Silvercrest Asset Management Group LLC220,535$3.62M0.02%+114,709+108.4%Added
Kennedy Capital Management, Inc.200,038$3.28M0.07%+163,571+448.5%Added
Norges Bank168,700$2.77M0.00%+124,509+281.8%Added
Renaissance Technologies LLC162,600$2.67M0.00%+162,600New
Susquehanna International Group, LLP149,605$2.45M0.00%+101,519+211.1%Added
American Century Companies Inc140,548$2.30M0.00%00.0%Unchanged
Voloridge Investment Management, LLC132,157$2.17M0.01%+132,157New
Deutsche Bank AG125,518$2.06M0.00%+31,877+34.0%Added
State Street Corp125,210$2.05M0.00%+7,356+6.2%Added
Russell Investments Group, Ltd.114,628$1.88M0.00%+9,664+9.2%Added
BNP Paribas Arbitrage, SA109,281$1.79M0.00%+108,584+15,578.8%Added
Picton Mahoney Asset Management99,785$1.64M0.06%−30,390−23.3%Reduced
PDT Partners, LLC97,421$1.60M0.12%+19,708+25.4%Added
Maso Capital Partners Ltd94,720$1.55M0.71%00.0%Unchanged
Swiss National Bank81,400$1.33M0.00%00.0%Unchanged
Ci Investments Inc.80,808$1.32M0.00%+45,100+126.3%Added
JPMorgan Chase & Co75,892$1.25M0.00%+44,913+145.0%Added
Industrial Alliance Investment Management Inc.70,350$1.15M0.03%+70,350New
North Growth Management Ltd.69,000$1.14M0.19%+6,000+9.5%Added
Raymond James Financial Services Advisors, Inc.64,099$1.05M0.00%−11,466−15.2%Reduced
ExodusPoint Capital Management, LP55,172$904.0K0.01%+11,047+25.0%Added
Citadel Advisors LLC54,525$894.0K0.00%+27,832+104.3%Added
Northern Trust Corp46,434$762.0K0.00%−50−0.1%Reduced
Cubist Systematic Strategies, LLC44,623$731.0K0.01%+36,029+419.2%Added
Marathon Capital Management44,340$727.0K0.17%−2,125−4.6%Reduced
TD Asset Management Inc42,262$693.0K0.00%00.0%Unchanged
Parkman Healthcare Partners LLC41,625$682.0K0.15%+11,625+38.8%Added
State of Wisconsin Investment Board39,665$650.0K0.00%+39,665New
Two Sigma Advisers, LP35,000$574.0K0.00%−60,400−63.3%Reduced
Blueshift Asset Management, LLC34,802$570.0K0.05%+34,802New
Nuveen Asset Management, LLC33,314$546.0K0.00%+33,314New
D. E. Shaw & Co., Inc.32,083$526.0K0.00%+23,836+289.0%Added
California State Teachers Retirement System31,497$516.0K0.00%+1,174+3.9%Added
Journey Strategic Wealth LLC28,846$473.0K0.05%+28,846New
Wells Fargo & Company26,473$434.0K0.00%−53,271−66.8%Reduced
Truist Financial Corp25,500$418.0K0.00%−500−1.9%Reduced
Commonwealth Equity Services, LLC25,261$414.0K0.00%+25,261New
Taylor Wealth Management Partners25,164$412.0K0.15%−41,804−62.4%Reduced
Algert Global LLC21,550$353.0K0.04%+9,350+76.6%Added
Bank of Montreal20,769$340.0K0.00%+7,032+51.2%Added
Royal Bank of Canada18,763$307.0K0.00%−1,170−5.9%Reduced
Allspring Global Investments Holdings, LLC18,294$299.0K0.00%+18,294New
Golden State Equity Partners17,793$292.0K0.15%+17,793New
Weiss Multi-Strategy Advisers LLC17,386$285.0K0.01%−71−0.4%Reduced
Jane Street Group, LLC15,790$259.0K0.00%+944+6.4%Added
Legal & General Group Plc14,570$239.0K0.00%+5,815+66.4%Added
Gsa Capital Partners LLP14,497$238.0K0.03%−35,504−71.0%Reduced
Tower Research Capital LLC (TRC)13,573$222.0K0.00%+5,742+73.3%Added
Evoke Wealth, LLC12,179$200.0K0.01%00.0%Unchanged
Raymond James Trust N.A.12,233$200.0K0.01%+550+4.7%Added
Prelude Capital Management, LLC11,700$192.0K0.01%+11,700New
Handelsbanken Fonder AB11,500$188.0K0.00%00.0%Unchanged
Virtus ETF Advisers LLC10,324$169.0K0.06%+4,727+84.5%Added
Janney Montgomery Scott LLC10,267$168.0K0.00%00.0%Unchanged
Ensign Peak Advisors, Inc8,270$136.0K0.00%−18,622−69.2%Reduced
Public Employees Retirement Association of Colorado7,991$131.0K0.00%00.0%Unchanged
Group One Trading, L.P.6,122$100.0K0.00%+6,122New
Zurcher Kantonalbank (Zurich Cantonalbank)4,097$67.0K0.00%00.0%Unchanged
Knott David M Jr4,000$66.0K0.02%+4,000New
UBS Group AG3,596$59.0K0.00%+3,246+927.4%Added
Aquatic Capital Management LLC3,100$51.0K0.10%+3,100New
Compagnie Lombard Odier SCmA3,000$49.0K0.00%00.0%Unchanged
Cutler Group LP2,942$48.0K0.00%−3,520−54.5%Reduced
Great West Life Assurance Co1,689$28.0K0.00%00.0%Unchanged
Rockefeller Capital Management L.P.1,387$22.0K0.00%00.0%Unchanged
Barclays PLC1,117$18.0K0.00%−4,769−81.0%Reduced
Macquarie Group Ltd871$14.0K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.790$13.0K0.00%−150−16.0%Reduced
Citigroup Inc810$13.0K0.00%+78+10.7%Added