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Zymeworks Inc.

ZYME
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001937653

No open-market purchases or sales by Zymeworks Inc. insiders were filed in the last 90 days; 202 institutions reported holding it in 13F filings for Q2 2026, worth $1.79B in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Zymeworks Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
114
−7 vs. Q3 2021
Shares held
42.3M
+5.53M (+15.0%) vs. Q3 2021
Total value
$693.9M
−$374.9M (−35.1%) vs. Q3 2021
New holders
22
43 more added
Sold out
29
26 more reduced

2 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ZYME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 114 institutions
Q1 2021: 125 institutionsQ2 2021: 109 institutionsQ3 2021: 123 institutionsQ4 2021: 114 institutionsQ1 2022: 120 institutionsQ2 2022: 114 institutionsQ3 2022: 91 institutionsQ4 2022: 96 institutionsQ1 2023: 116 institutionsQ2 2023: 137 institutionsQ3 2023: 140 institutionsQ4 2023: 157 institutionsQ1 2024: 171 institutionsQ2 2024: 164 institutionsQ3 2024: 163 institutionsQ4 2024: 174 institutionsQ1 2025: 186 institutionsQ2 2025: 182 institutionsQ3 2025: 184 institutionsQ4 2025: 210 institutionsQ1 2026: 212 institutionsQ2 2026: 202 institutions
Value heldQ4 2021: $693.9M
Q1 2021: $1.12BQ2 2021: $1.20BQ3 2021: $1.07BQ4 2021: $693.9MQ1 2022: $327.3MQ2 2022: $253.3MQ3 2022: $293.7MQ4 2022: $449.9MQ1 2023: $512.6MQ2 2023: $547.9MQ3 2023: $395.5MQ4 2023: $674.0MQ1 2024: $713.0MQ2 2024: $580.6MQ3 2024: $834.7MQ4 2024: $973.2MQ1 2025: $840.9MQ2 2025: $949.0MQ3 2025: $1.26BQ4 2025: $1.88BQ1 2026: $1.76BQ2 2026: $1.79B
Institutions holding ZYME and their total value by quarter
QuarterHoldersValue
Q2 2026202$1.79B
Q1 2026212$1.76B
Q4 2025210$1.88B
Q3 2025184$1.26B
Q2 2025182$949.0M
Q1 2025186$840.9M
Q4 2024174$973.2M
Q3 2024163$834.7M
Q2 2024164$580.6M
Q1 2024171$713.0M
Q4 2023157$674.0M
Q3 2023140$395.5M
Q2 2023137$547.9M
Q1 2023116$512.6M
Q4 202296$449.9M
Q3 202291$293.7M
Q2 2022114$253.3M
Q1 2022120$327.3M
Q4 2021114$693.9M
Q3 2021123$1.07B
Q2 2021109$1.20B
Q1 2021125$1.12B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Zymeworks Inc.; share changes are against Q3 2021.

Institutions holding ZYME in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Toronto Dominion Bank16$00.00%00.0%Unchanged
Asset Dedication, LLC47$1.00K0.00%00.0%Unchanged
American Portfolios Advisors102$1.67K0.00%00.0%Unchanged
TD Waterhouse Canada Inc.96$1.98K0.00%+96New
Allworth Financial LP114$2.00K0.00%00.0%Unchanged
Eagle Bay Advisors LLC110$2.00K0.00%+110New
Steward Partners Investment Advisory, LLC158$3.00K0.00%−7−4.2%Reduced
US Bancorp347$5.00K0.00%−326−48.4%Reduced
IFP Advisors, Inc300$5.00K0.00%00.0%Unchanged
HighMark Wealth Management LLC280$5.00K0.00%00.0%Unchanged
State of Wyoming382$6.00K0.00%+31+8.8%Added
Dark Forest Capital Management LP362$6.00K0.00%+362New
National Bank of Canada600$10.0K0.00%+600New
Advisor Group Holdings, Inc.790$13.0K0.00%−150−16.0%Reduced
Citigroup Inc810$13.0K0.00%+78+10.7%Added
Macquarie Group Ltd871$14.0K0.00%00.0%Unchanged
Barclays PLC1,117$18.0K0.00%−4,769−81.0%Reduced
Rockefeller Capital Management L.P.1,387$22.0K0.00%00.0%Unchanged
Great West Life Assurance Co1,689$28.0K0.00%00.0%Unchanged
Cutler Group LP2,942$48.0K0.00%−3,520−54.5%Reduced
Compagnie Lombard Odier SCmA3,000$49.0K0.00%00.0%Unchanged
Aquatic Capital Management LLC3,100$51.0K0.10%+3,100New
UBS Group AG3,596$59.0K0.00%+3,246+927.4%Added
Knott David M Jr4,000$66.0K0.02%+4,000New
Zurcher Kantonalbank (Zurich Cantonalbank)4,097$67.0K0.00%00.0%Unchanged
Group One Trading, L.P.6,122$100.0K0.00%+6,122New
Public Employees Retirement Association of Colorado7,991$131.0K0.00%00.0%Unchanged
Ensign Peak Advisors, Inc8,270$136.0K0.00%−18,622−69.2%Reduced
Janney Montgomery Scott LLC10,267$168.0K0.00%00.0%Unchanged
Virtus ETF Advisers LLC10,324$169.0K0.06%+4,727+84.5%Added
Handelsbanken Fonder AB11,500$188.0K0.00%00.0%Unchanged
Prelude Capital Management, LLC11,700$192.0K0.01%+11,700New
Evoke Wealth, LLC12,179$200.0K0.01%00.0%Unchanged
Raymond James Trust N.A.12,233$200.0K0.01%+550+4.7%Added
Tower Research Capital LLC (TRC)13,573$222.0K0.00%+5,742+73.3%Added
Gsa Capital Partners LLP14,497$238.0K0.03%−35,504−71.0%Reduced
Legal & General Group Plc14,570$239.0K0.00%+5,815+66.4%Added
Jane Street Group, LLC15,790$259.0K0.00%+944+6.4%Added
Weiss Multi-Strategy Advisers LLC17,386$285.0K0.01%−71−0.4%Reduced
Golden State Equity Partners17,793$292.0K0.15%+17,793New
Allspring Global Investments Holdings, LLC18,294$299.0K0.00%+18,294New
Royal Bank of Canada18,763$307.0K0.00%−1,170−5.9%Reduced
Bank of Montreal20,769$340.0K0.00%+7,032+51.2%Added
Algert Global LLC21,550$353.0K0.04%+9,350+76.6%Added
Taylor Wealth Management Partners25,164$412.0K0.15%−41,804−62.4%Reduced
Commonwealth Equity Services, LLC25,261$414.0K0.00%+25,261New
Truist Financial Corp25,500$418.0K0.00%−500−1.9%Reduced
Wells Fargo & Company26,473$434.0K0.00%−53,271−66.8%Reduced
Journey Strategic Wealth LLC28,846$473.0K0.05%+28,846New
California State Teachers Retirement System31,497$516.0K0.00%+1,174+3.9%Added
D. E. Shaw & Co., Inc.32,083$526.0K0.00%+23,836+289.0%Added
Nuveen Asset Management, LLC33,314$546.0K0.00%+33,314New
Blueshift Asset Management, LLC34,802$570.0K0.05%+34,802New
Two Sigma Advisers, LP35,000$574.0K0.00%−60,400−63.3%Reduced
State of Wisconsin Investment Board39,665$650.0K0.00%+39,665New
Parkman Healthcare Partners LLC41,625$682.0K0.15%+11,625+38.8%Added
TD Asset Management Inc42,262$693.0K0.00%00.0%Unchanged
Marathon Capital Management44,340$727.0K0.17%−2,125−4.6%Reduced
Cubist Systematic Strategies, LLC44,623$731.0K0.01%+36,029+419.2%Added
Northern Trust Corp46,434$762.0K0.00%−50−0.1%Reduced
Citadel Advisors LLC54,525$894.0K0.00%+27,832+104.3%Added
ExodusPoint Capital Management, LP55,172$904.0K0.01%+11,047+25.0%Added
Raymond James Financial Services Advisors, Inc.64,099$1.05M0.00%−11,466−15.2%Reduced
North Growth Management Ltd.69,000$1.14M0.19%+6,000+9.5%Added
Industrial Alliance Investment Management Inc.70,350$1.15M0.03%+70,350New
JPMorgan Chase & Co75,892$1.25M0.00%+44,913+145.0%Added
Ci Investments Inc.80,808$1.32M0.00%+45,100+126.3%Added
Swiss National Bank81,400$1.33M0.00%00.0%Unchanged
Maso Capital Partners Ltd94,720$1.55M0.71%00.0%Unchanged
PDT Partners, LLC97,421$1.60M0.12%+19,708+25.4%Added
Picton Mahoney Asset Management99,785$1.64M0.06%−30,390−23.3%Reduced
BNP Paribas Arbitrage, SA109,281$1.79M0.00%+108,584+15,578.8%Added
Russell Investments Group, Ltd.114,628$1.88M0.00%+9,664+9.2%Added
State Street Corp125,210$2.05M0.00%+7,356+6.2%Added
Deutsche Bank AG125,518$2.06M0.00%+31,877+34.0%Added
Voloridge Investment Management, LLC132,157$2.17M0.01%+132,157New
American Century Companies Inc140,548$2.30M0.00%00.0%Unchanged
Susquehanna International Group, LLP149,605$2.45M0.00%+101,519+211.1%Added
Renaissance Technologies LLC162,600$2.67M0.00%+162,600New
Norges Bank168,700$2.77M0.00%+124,509+281.8%Added
Kennedy Capital Management, Inc.200,038$3.28M0.07%+163,571+448.5%Added
Silvercrest Asset Management Group LLC220,535$3.62M0.02%+114,709+108.4%Added
Raymond James & Associates228,424$3.74M0.00%−65,398−22.3%Reduced
Vanguard Group Inc233,817$3.83M0.00%+62,261+36.3%Added
Platinum Investment Management Ltd235,299$3.86M0.11%+79,887+51.4%Added
Timelo Investment Management Inc.235,898$3.87M2.07%+235,898New
SG Americas Securities, LLC269,151$4.41M0.03%+49,049+22.3%Added
Vivo Capital, LLC286,064$4.69M0.28%00.0%Unchanged
Thrivent Financial for Lutherans287,140$4.71M0.01%−81,963−22.2%Reduced
Sofinnova Investments, Inc.392,712$6.44M0.41%−17,907−4.4%Reduced
UBS Asset Management Americas Inc410,215$6.72M0.00%−257,774−38.6%Reduced
Artal Group S.A.450,000$7.38M0.22%00.0%Unchanged
Millennium Management LLC514,915$8.44M0.01%+275,102+114.7%Added
Cormorant Asset Management, LP600,000$9.83M0.58%−350,000−36.8%Reduced
Alyeska Investment Group, L.P.670,340$11.0M0.13%+374,417+126.5%Added
Point72 Asset Management, L.P.750,500$12.3M0.05%+750,500New
Camber Capital Management LP800,000$13.1M0.51%+50,000+6.7%Added
BlackRock Inc.811,098$13.3M0.00%+32,799+4.2%Added
Redmile Group, LLC874,397$14.3M0.33%−7,700−0.9%Reduced
BNP PARIBAS ASSET MANAGEMENT Holding S.A.1,145,718$18.8M0.06%+296,993+35.0%Added