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Zymeworks Inc.

ZYME
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001937653

No open-market purchases or sales by Zymeworks Inc. insiders were filed in the last 90 days; 202 institutions reported holding it in 13F filings for Q2 2026, worth $1.79B in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Zymeworks Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
186
+15 vs. Q4 2024
Shares held
70.6M
+5.43M (+8.3%) vs. Q4 2024
Total value
$840.9M
−$113.0M (−11.8%) vs. Q4 2024
New holders
32
60 more added
Sold out
17
64 more reduced

3 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ZYME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 186 institutions
Q1 2021: 125 institutionsQ2 2021: 109 institutionsQ3 2021: 123 institutionsQ4 2021: 114 institutionsQ1 2022: 120 institutionsQ2 2022: 114 institutionsQ3 2022: 91 institutionsQ4 2022: 96 institutionsQ1 2023: 116 institutionsQ2 2023: 137 institutionsQ3 2023: 140 institutionsQ4 2023: 157 institutionsQ1 2024: 171 institutionsQ2 2024: 164 institutionsQ3 2024: 163 institutionsQ4 2024: 174 institutionsQ1 2025: 186 institutionsQ2 2025: 182 institutionsQ3 2025: 184 institutionsQ4 2025: 210 institutionsQ1 2026: 212 institutionsQ2 2026: 202 institutions
Value heldQ1 2025: $840.9M
Q1 2021: $1.12BQ2 2021: $1.20BQ3 2021: $1.07BQ4 2021: $693.9MQ1 2022: $327.3MQ2 2022: $253.3MQ3 2022: $293.7MQ4 2022: $449.9MQ1 2023: $512.6MQ2 2023: $547.9MQ3 2023: $395.5MQ4 2023: $674.0MQ1 2024: $713.0MQ2 2024: $580.6MQ3 2024: $834.7MQ4 2024: $973.2MQ1 2025: $840.9MQ2 2025: $949.0MQ3 2025: $1.26BQ4 2025: $1.88BQ1 2026: $1.76BQ2 2026: $1.79B
Institutions holding ZYME and their total value by quarter
QuarterHoldersValue
Q2 2026202$1.79B
Q1 2026212$1.76B
Q4 2025210$1.88B
Q3 2025184$1.26B
Q2 2025182$949.0M
Q1 2025186$840.9M
Q4 2024174$973.2M
Q3 2024163$834.7M
Q2 2024164$580.6M
Q1 2024171$713.0M
Q4 2023157$674.0M
Q3 2023140$395.5M
Q2 2023137$547.9M
Q1 2023116$512.6M
Q4 202296$449.9M
Q3 202291$293.7M
Q2 2022114$253.3M
Q1 2022120$327.3M
Q4 2021114$693.9M
Q3 2021123$1.07B
Q2 2021109$1.20B
Q1 2021125$1.12B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Zymeworks Inc.; share changes are against Q4 2024.

Institutions holding ZYME in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Zurcher Kantonalbank (Zurich Cantonalbank)24,531$292.2K0.00%+4,920+25.1%Added
Price T Rowe Associates Inc24,113$288.0K0.00%+2,530+11.7%Added
Duncan Williams Asset Management, LLC22,095$263.2K0.10%+22,095New
Schonfeld Strategic Advisors LLC21,900$260.8K0.00%−900−3.9%Reduced
Cresset Asset Management, LLC21,320$253.9K0.00%−9,486−30.8%Reduced
Manufacturers Life Insurance Company, The20,460$243.7K0.00%−498−2.4%Reduced
XTX Topco Ltd20,205$240.6K0.01%−13,497−40.0%Reduced
Janus Henderson Group PLC18,200$225.0K0.00%00.0%Unchanged
Susquehanna Fundamental Investments, LLC17,090$203.5K0.00%−80,463−82.5%Reduced
Voya Investment Management LLC15,653$186.4K0.00%−43,861−73.7%Reduced
State Board of Administration of Florida Retirement System15,340$182.7K0.00%00.0%Unchanged
ProShare Advisors LLC14,912$177.6K0.00%−3,711−19.9%Reduced
Quantinno Capital Management LP14,245$169.7K0.00%+14,245New
China Universal Asset Management Co., Ltd.13,816$164.5K0.02%−789−5.4%Reduced
New York State Common Retirement Fund13,371$159.2K0.00%00.0%Unchanged
Virtus Investment Advisers, Inc.13,006$154.9K0.04%+13,006New
FMR LLC12,830$152.8K0.00%−9,136−41.6%Reduced
Magnetar Financial LLC12,448$148.3K0.00%+12,448New
Engineers Gate Manager LP12,399$147.7K0.00%+12,399New
CIBC World Markets Corp12,102$144.1K0.00%+12,102New
Shell Asset Management Co12,101$144.0K0.01%−256−2.1%Reduced
Jacobs Levy Equity Management, Inc12,040$143.4K0.00%−344,128−96.6%Reduced
Arizona State Retirement System11,846$141.1K0.00%−1,566−11.7%Reduced
Creative Planning11,822$140.8K0.00%+11,765+20,640.4%Added
Police & Firemen's Retirement System of New Jersey11,669$139.0K0.00%00.0%Unchanged
Janney Montgomery Scott LLC11,567$138.0K0.00%+1,300+12.7%Added
Teacher Retirement System of Texas11,168$133.0K0.00%−2,575−18.7%Reduced
Man Group plc10,859$129.3K0.00%+10,859New
James Investment Research Inc10,578$126.0K0.02%00.0%Unchanged
One Wealth Advisors, LLC10,404$123.9K0.02%−3,575−25.6%Reduced
KLP Kapitalforvaltning AS10,300$122.7K0.00%00.0%Unchanged
Exchange Traded Concepts, LLC10,126$120.6K0.00%−3,260−24.4%Reduced
TPG Financial Advisors, LLC10,017$119.3K0.05%00.0%Unchanged
Northwest & Ethical Investments L.P.10,030$119.3K0.00%+4,559+83.3%Added
Ameritas Investment Partners, Inc.5,616$66.9K0.00%00.0%Unchanged
Clearstead Advisors, LLC5,000$59.5K0.00%00.0%Unchanged
Simplex Trading, LLC4,168$49.0K0.00%+3,081+283.4%Added
BNP Paribas Arbitrage, SA4,000$47.6K0.00%−3,363−45.7%Reduced
DekaBank Deutsche Girozentrale3,843$47.0K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)3,816$45.4K0.00%−5,888−60.7%Reduced
Lazard Asset Management LLC3,787$45.0K0.00%+3,787New
Russell Investments Group, Ltd.3,053$36.4K0.00%−41,892−93.2%Reduced
Mirae Asset Global Investments Co., Ltd.2,330$28.8K0.00%+35+1.5%Added
CWM, LLC2,299$27.0K0.00%+2,106+1,091.2%Added
Aquatic Capital Management LLC2,049$24.4K0.00%+2,049New
Amalgamated Bank1,880$22.0K0.00%+81+4.5%Added
GF Fund Management Co. Ltd.1,763$21.0K0.00%+317+21.9%Added
Curio Wealth, LLC1$14.6K0.01%−999−99.9%Reduced
Sterling Capital Management LLC941$11.2K0.00%−778−45.3%Reduced
Wayfinding Financial, LLC981$11.0K0.00%+981New
Federation des caisses Desjardins du Quebec870$10.4K0.00%+810+1,350.0%Added
GAMMA Investing LLC543$6.47K0.00%+10+1.9%Added
National Bank of Canada524$6.24K0.00%−24−4.4%Reduced
US Bancorp423$5.04K0.00%−65−13.3%Reduced
Smartleaf Asset Management LLC401$4.96K0.00%+158+65.0%Added
Advisor Group Holdings, Inc.405$4.82K0.00%−312−43.5%Reduced
Lindbrook Capital, LLC371$4.42K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC332$3.95K0.00%00.0%Unchanged
Parallel Advisors, LLC329$3.92K0.00%00.0%Unchanged
Truvestments Capital LLC309$3.68K0.00%−125−28.8%Reduced
TD Waterhouse Canada Inc.311$3.60K0.00%00.0%Unchanged
Skopos Labs, Inc.289$3.44K0.00%−300−50.9%Reduced
HighMark Wealth Management LLC280$3.33K0.00%00.0%Unchanged
Daiwa Securities Group Inc.286$3.00K0.00%00.0%Unchanged
Aster Capital Management (DIFC) Ltd217$2.91K0.00%+147+210.0%Added
The PNC Financial Services Group, Inc.230$2.74K0.00%−54−19.0%Reduced
Meeder Asset Management Inc206$2.45K0.00%+206New
Parkside Financial Bank & Trust156$1.86K0.00%+156New
Farther Finance Advisors, LLC139$1.61K0.00%−11−7.3%Reduced
Coldstream Capital Management Inc129$1.54K0.00%+129New
Allworth Financial LP110$1.38K0.00%+76+223.5%Added
Amundi106$1.25K0.00%+54+103.8%Added
Group One Trading, L.P.100$1.19K0.00%−700−87.5%Reduced
Rothschild Investment LLC100$1.19K0.00%+50+100.0%Added
Steward Partners Investment Advisory, LLC53$6310.00%00.0%Unchanged
Stephens Consulting, LLC30$3580.00%+30New
True Wealth Design, LLC20$2390.00%+20New
Ameriflex Group, Inc.20$2380.00%+20New
Signaturefd, LLC19$2260.00%+19New
CoreCap Advisors, LLC18$2140.00%00.0%Unchanged
EverSource Wealth Advisors, LLC13$1550.00%+3+30.0%Added
Versant Capital Management, Inc12$1430.00%+12New
SBI Securities Co., Ltd.10$1190.00%00.0%Unchanged
Innovative Advisory Group, LLC8$950.00%00.0%Unchanged
IFP Advisors, Inc0$480.00%0Unchanged
Covestor Ltd27$00.00%00.0%Unchanged
Point72 Asset Management, L.P.0$00.00%−330,127−100.0%Sold out
Acadian Asset Management LLC0$00.00%−230,970−100.0%Sold out
Panagora Asset Management Inc0$00.00%−214,338−100.0%Sold out
Ameriprise Financial Inc0$00.00%−121,526−100.0%Sold out
Public Employees Retirement System of Ohio0$00.00%−50,583−100.0%Sold out
STRS Ohio0$00.00%−49,000−100.0%Sold out
Jump Financial, LLC0$00.00%−48,612−100.0%Sold out
Polar Asset Management Partners Inc.0$00.00%−36,000−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−21,868−100.0%Sold out
Monaco Asset Management SAM0$00.00%−15,000−100.0%Sold out
Jain Global LLC0$00.00%−10,010−100.0%Sold out
Compagnie Lombard Odier SCmA0$00.00%−7,000−100.0%Sold out
Virtus ETF Advisers LLC0$00.00%−5,633−100.0%Sold out
SRS Capital Advisors, Inc.0$00.00%−169−100.0%Sold out